The dual role of CXCL9/SPP1 polarized tumor-associated macrophages in modulating anti-tumor immunity in hepatocellular carcinoma by Yu Gu, Zhihui Zhang, Hao Huang, Wenyong Zhu, Hongjia Liu, Rongxin Zhang, Nan Weng, Xiao Sun

“…Based on medical imaging data, we developed a radiomics tool, RCSP (Radiogenomics-based CXCL9/SPP1 Polarity), to assist in non-invasively predicting the CS polarity in HCC patients.ConclusionOur research sheds light on the regulatory roles of SPP1+ TAMs and CXCL9+ TAMs in the micro-environment and provides new therapeutic targets or insights for the reprogramming of targeted macrophages in HCC.…”
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Machine learning-based viewers’ preference prediction on social awareness advertisements using EEG by Farhan Ishtiaque, Mohammad Tohidul Islam Miya, Fazla Rabbi Mashrur, Khandoker Mahmudur Rahman, Ravi Vaidyanathan, Syed Ferhat Anwar, Farhana Sarker, Noor Azman Ali, Huam Hon Tat, Khondaker A. Mamun, Khondaker A. Mamun

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Gene expression changes in human cerebral arteries following hemoglobin exposure: implications for vascular responses in SAH by Chathathayil M. Shafeeque, Arif O. Harmanci, Sithara Thomas, Ari C. Dienel, Devin W. McBride, Kumar T. Peeyush, Spiros L. Blackburn

“…While animal models have provided substantial and invaluable data in the research of aneurysmal SAH, the specific effects of subarachnoid blood on cerebral arteries remain greatly understudied. …”
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FacaDiffy: Inpainting unseen facade parts using diffusion models by T. Fröch, O. Wysocki, Y. Xia, Y. Xia, J. Xie, B. Schwab, D. Cremers, D. Cremers, T. H. Kolbe

“…To complement the scarcity of real-world training data, we also develop a scalable pipeline to produce synthetic conflict maps using random city model generators and annotated facade images. …”
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The Wizard Apprentice: A Serious Games System in Immersive VR as a Feasible Rehabilitation Approach in Children With Cerebral Palsy by Cristian Camardella, Federica Serra, Caterina Linciano, Chiara Malasoma, Gabriele Carrieri, Sara Aliboni, Ilaria Bortone, Federico Posteraro, Luca Bonfiglio, Daniele Leonardis

“…The presented pilot study (12 CP children, 24 sessions), focuses on the feasibility assessment of the rehabilitation method, then, it allows a more in depth analysis on the adaptation and progress of the exercise parameters through data recorded during the whole treatment. …”
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A distributed brain response predicting the facial expression of acute nociceptive pain by Marie-Eve Picard, Miriam Kunz, Jen-I Chen, Michel-Pierre Coll, Etienne Vachon-Presseau, Tor D Wager, Pierre Rainville

“…We then applied a multivariate pattern analysis to the fMRI data to predict the facial expression of pain. …”
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Energy management system for PV-based distributed generators in AC microgrids using an adapted JAYA optimizer to minimize operational costs, energy losses, and CO2 emissions by Nicolás Ignacio Labra-Cáceres, Luis Fernando Grisales-Noreña, Rubén Iván Bolaños, Jhony Andrés Guzmán-Henao, Oscar Danilo Montoya

“…To solve the model, an adapted version of the JAYA optimization algorithm was implemented, and its performance was compared against four established methodologies: the Chu & Beasley Genetic Algorithm (CBGA), Particle Swarm Optimization (PSO), the Vortex Search Algorithm (VSA), and Ant Lion Optimization (ALO). The analysis was conducted using two test microgrids: one with 33 nodes operating in grid-connected mode and another with 27 nodes operating in islanded mode, utilizing generation and demand data from Medellín and Capurganá, Colombia. …”
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Interannual Variations in Spring Snowmelt Timing of Alaskan Black Spruce Forests Using a Bulk‐Surface Energy Balance Approach by Hiroki Ikawa, Taro Nakai, Robert C. Busey, Yoshinobu Harazono, Kyoko Ikeda, Hiroki Iwata, Hirohiko Nagano, Kazuyuki Saito, Masahito Ueyama, Hideki Kobayashi

“…Abstract Spring snowmelt occurs for a short duration on an annual time scale, but their timings considerably affect the carbon and hydrological cycle in high‐latitude ecosystems. Here, we developed a simple snowmelt model, treating the ecosystem surface as a bulk‐surface layer. …”
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The experiences of family members of persons with intellectual disabilities who used residential care homes during the COVID-19 pandemic by Montserrat Puig Llobet, Montserrat Roca Roger, Teresa Nicolàs Silva, Gemma Pérez Gimenez, Zaida Agüera, Maria-Teresa Lluch Canut, Juan Francisco Roldan Merino, Carmen Moreno Arroyo, Marta Prats Arimon, Maria Aurelia Sánchez Ortega, Xavier Domènech Mascaró, Miguel Angel Hidalgo Blanco, Antonio Moreno Poyato

“…Results Our analysis identified 4 main themes that developed into additional factors: the decision to stay at home or in the residence, fear, illness, and protocol. …”
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Tree‐Ring Insights Into Past and Future Streamflow Variations in Beijing, Northern China by Honghua Cao, Feng Chen, Mao Hu, Tiyuan Hou, Xiaoen Zhao, Shijie Wang, Heli Zhang

“…Comparison of the runoff reconstruction results with climate grid data demonstrated a large magnitude of climate change in North China during the study period. …”
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‘With this study, we have hope that something is coming’: community members’ perceptions of HIV cure-related research in Durban, South Africa – a qualitative focus group study... by Karine Dubé, Deli Mthimkhulu, Wiseman Ngcobo, Deborah Mindry, Luyanda Maphalala, Vanessa Pillay, Whitney Tran, Ana Korolkova, Thumbi Ndung’u, Krista Dong

“…We transcribed audio recordings verbatim and used content analysis to analyze the data. Results Twenty community members (13 women and 7 men) participated in three focus groups (HIV status not included). …”
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A retrospective assessment of COVID-19 vulnerability index indicators and mortality rates pre-COVID-19 (2018–2020) and during COVID-19 (2020–2022) in a health and demographic surve... by Takwanisa Machemedze, Chodziwadziwa Whiteson Kabudula, Jean Juste Harrisson Bashingwa, Beth A. Tippett Barr, Nellie Myburgh, Sana Mahtab, Cleopas Hwinya, Stephen Tollman, Ziyaad Dangor, Shabir A. Madhi

“…We evaluated mortality rates and risk of death, prior to and during the COVID-19 pandemic, in relation to an individual’s COVID-19 vulnerability, based on a scoring algorithm developed in South Africa. Methods The analysis was undertaken using data from a health and demographic surveillance system (HDSS) in Soweto and Thembelihle, Gauteng, South Africa. …”
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Human papillomavirus in vulvar cancer: a systematic review by D. S. Dolgasheva, M. K. Ibragimova, E. A. Kravtsova, I. A. Tsydenova, K. A. Gaptulbarova, M. M. Tsyganov, N. V. Litviakov

“…It is established that vulvar squamous cell cancer develops via two pathways. In the first scenario, the tumor may develop during vulvar dystrophic diseases such as scleroatrophic lichen and differentiated intraepithelial neoplasia. …”
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Preferences for and drivers of adult vaccination clinic site selection: A cross-sectional study in 30 provinces in China by Yuxi Liu, Yanlin Cao, Yugang Li, Siyuan Liu, Yunshao Xu, Weizhong Yang, Luzhao Feng

“…This contributes to developing more efficient, patient-focused vaccination strategies that tackle vaccine hesitancy and improve access to vaccination sites. …”
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Small Scale Multi-Object Segmentation in Mid-Infrared Image Using the Image Timing Features–Gaussian Mixture Model and Convolutional-UNet by Meng Lv, Haoting Liu, Mengmeng Wang, Dongyang Wang, Haiguang Li, Xiaofei Lu, Zhenhui Guo, Qing Li

“…Unlike the basic Gaussian Mixture Model (GMM), the proposed model dynamically adjusts the learning rate according to the content difference between adjacent frames and optimizes the number of Gaussian distributions through time series histogram analysis of pixels. Second, a segmentation framework based on Con-UNet is developed to improve the feature extraction ability of UNet. …”
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Comparative metabolome and transcriptome revealed the CpODO1 transcription factor controlling the varied floral scent traits of three wintersweet cultivars by Yubing Yong, Qi Zhou, Xin Ding, Jianming Cheng, Chengcheng Zhou, Zhiguo Shen, Lin Zhang

“…Overexpression of CpODO1 can enhance the production of benzyl alcohol in transgenic tobacco flowers. Analysis of DAP-seq data, EMSA and dual-luciferase assay revealed that CpODO1 predominantly regulate the expression of CpCYP71, a cytochrome P450 gene encoding a key enzyme in the production of benzyl alcohol, and the transcriptional regulation of CpODO1 is driven by CpEOBII. …”
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A semantic segmentation-based automatic pterygium assessment and grading system by Qingbo Ji, Qingbo Ji, Wanyang Liu, Wanyang Liu, Qingfeng Ma, Qingfeng Ma, Lijun Qu, Lin Zhang, Hui He

“…The construction of the data set should continue to be optimized in future studies.…”
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Psychosocial considerations in pediatric heart transplantation: Initial validation of the Pediatric Psychosocial Assessment Tool at a single center by Michael O. Killian, PhD, MSW, Sonnie E. Mayewski, MSW, Schyler E. Brumm, MSW, Zhe He, PhD, Dipankar Gupta, MBBS, DCH, MD

“…Methods: This study presents initial validation data for the PPAT, based on 189 assessments conducted at a large pediatric heart transplant center. …”
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Magnetic nanoparticles and quantum dots coupled immuno nano fluorescence assay for visual detection of HPV16-induced cervical cancer cells from cytology/biopsy samples by Srishty Raman, Pranay Tanwar, Jyoti Meena, Neerja Bhatla, Subhash C. Yadav

“…Biopsy-based histopathology and immunohistochemistry for cervical cancer detection are costly, time-consuming, and require expert personnel for data interpretation. We developed a simple magnetic nanoparticle (MNPs) and quantum dots (QD) coupled immuno nano fluorescence assay (MNPQDCINFA) for visual detection of HPV16-induced cervical cancer cells under UV light from cytology/biopsy samples exploiting host cancer cells expressing viral E7 protein as a biomarker. …”
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pH-Responsive Bacterial Nanocellulose Smart Labels Derived from Acid Whey for Estimating Beef Mince Quality Alterations During Storage by Dylan Zhe Liu, Sabeen Hassan, Benjamin M. Long, Alan Labas, Jayendra K. Amamcharla, Michelle J. Y. Yoo, Xiaojie Hu, David C. Bean

“…This study develops a pH-responsive label by incorporating anthocyanin from <i>Clitoria ternatea</i> into a bacterial nanocellulose (BNC) film derived from acid whey fermentation. …”
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