Disrupción tecnológica, ¿abandono social?* by Christophe Degryse

“…Discute la posibilidad de que el surgimiento de la economía de plataformas pueda llevar a la desaparición de la empresa tradicional y advierte la existencia de algunas tendencias que darían nacimiento a un nuevo modelo de negocios que abandona el campo de las relaciones sociales al situarse directamente entre la empresa jerarquizada y el mercado. …”
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Tolerogenic Splenic IDO+ Dendritic Cells from the Mice Treated with Induced-Treg Cells Suppress Collagen-Induced Arthritis by Jie Yang, Yiming Yang, Huahua Fan, Hejian Zou

“…Collectively, these findings suggest that transferred iTregs could induce tolerogenic characteristics in splenic DCs and these cells could effectively dampen CIA in an IDO-dependent manner. Thus, the potential therapeutic effects of iTregs in CIA are likely maintained through the generation of tolerogenic DCs in vivo.…”
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Juvenile Cosmology; Or Richard Powers’ Post-Global Doughnut by Judith Roof

“…It spins tales like a revolving planet, wheeling solar system, or careening galaxy. The consciousness enacted by Operation Wandering Soul is not defined, thus, only as the perspective of its wandering soul surgeon protagonist Kraft, but as the accruing of all time and place, layered as an enactment of a complex and networked consciousness belonging to no one and everyone. …”
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Na pograniczu auto/biografii. „Mama” Suzanne Osten by Tadeusz Szczepański

“…Na główny temat filmu składa się zatem daremne dążenie Gerd Osten do filmowej autoekspresji, które jednocześnie tworzy jego autobiograficzny i autotematyczny wymiar: oto córka realizuje marzenie matki, rekonstruując w swoim filmie jej portret jako kobiety bez reszty skoncentrowanej na spełnieniu tego właśnie marzenia, którego jednak nie jest w stanie urzeczywistnić. …”
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CAR T cells for treating autoimmune diseases by Dimitrios Mougiakakos, Ulrike Koehl, Stephan Fricke, Ulrich Blache, Sandy Tretbar

“…Furthermore, in preclinical models, researchers have also developed chimeric autoantibody receptor T cells that can eliminate individual B cell clones producing specific autoantibodies, and regulatory CAR T cells that do not eliminate autoreactive immune cells but dampen their wrong activation. Finally, we will address safety and manufacturing aspects for CAR T cells and discuss mRNA technologies and automation concepts for ensuring the future availability of safe and efficient CAR T cell products.…”
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Site Selection of Appropriate Locations for Development of Orchards Using GIS & RS, by Emphasizing Climatic Factors (Case study: Walnut - Tehran Province) by Fatemeh Falahati, Bahlool Alijani, Manizha Ghohrodi Tali, Mohammadjavad Barati

“…In this study incompatibility of each parameter results in the destruction of the plant and barrenness of the region, so at first step, According to F.A.O classification elevation and slope were determined, as the two main factors, and digital data of them were analyzed, hereby non-potential areas were removed. …”
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Bi-targeting of thioredoxin 1 and telomerase by thiotert promotes cell death of myelodysplastic syndromes and lymphoma by Qiangan Jing, Yunyi Wu, Yanchun Li, Chaoting Zhou, Junyu Zhang, Jun Xia, Keyi Li, Yuhuan Shen, Hongfeng Yao, Xiangmin Tong, Jing Du, Lushan Yu, Ying Wang

“…Meanwhile, pharmacological administration of glutathione (GSH), N-acetylcysteine (NAC), and mitoquinone (MitoQ), or genetic overexpression of TRX1 or TERT in MDS and cells could dampen the toxicity caused by thiotert. Remarkably, the in vivo mouse model of MDS demonstrated that thiotert administration exhibited greater efficacy in tumor reduction compared to the conventional chemotherapy drug cytarabine. …”
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Enhanced Surveillance of Acute Hepatitis B and C in Four Health Regions in Canada, 1998 TO 1999 by Shimian Zou, Jun Zhang, Martin Tepper, Antonio Giulivi, Beverley Baptiste, Gerry Predy, Darlene Poliquin, Manon Morin, Donna Jones, Joy Loewen, Margaret Ogonowski, Stephen Moses, Lawrence Elliott

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Collaborative Online Learning: Plurilingual and Pluricultural Development by O. Polyakova, I. N. Goryacheva, R. Galstyan-Sargsyan

“…Participants were university students aged 20–23 from Teaching Training Faculties from Lomonosov Moscow State University and CEU Cardenal Herrera University. The undergraduates who volunteered to participate in the focus group took part in five telecollaboration sessions (March-May 2020). …”
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Effects of Purple Rice and Morchella esculenta Powder Substitution on the Quality of Dough and Bread by Yuyue QIN, Hongda YU, Kejun CHEN, Guiguang CHENG, Jiliang ZHANG, Thanapop SOTEYOME

“…When the Morchella esculenta powder substitution content maintained was 3%, the content of purple rice powder was in the range from 0 to 12%, the L* value of bread crust and crumb gradually decreased and the ΔE value gradually increased, resulting in a darker color when compared to control group. The substitution of purple rice and Morchella esculenta powder decelerated the starch hydrolysis rate of bread. …”
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Therapeutic Effect and Location of GFP-Labeled Placental Mesenchymal Stem Cells on Hepatic Fibrosis in Rats by Jiong Yu, Guangshu Hao, Dan Wang, Jingqi Liu, Xiaotian Dong, Yanni Sun, Qiaoling Pan, Yang Li, Xiaowei Shi, Lanjuan Li, Hongcui Cao

“…We demonstrated that liver fibrosis was significantly dampened in the hPMSC transplantation group according to the Laennec fibrosis scoring system and histological data. …”
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A Comparative Evaluation of Carcass Quality, Nutritional Value, and Consumer Preference of Oreochromis niloticus from Two Impoundments with Different Pollution Levels in Zimbabwe by Vimbai R. Hamandishe, Petronella T. Saidi, Venancio E. Imbayarwo-Chikosi, Tamuka Nhiwatiwa

“…Lake Chivero fish were darker, greener, and less red while Lake Kariba fish were lighter, less green, and less red. …”
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Neuropeptides SP and CGRP Diminish the Moraxella catarrhalis Outer Membrane Vesicle- (OMV-) Triggered Inflammatory Response of Human A549 Epithelial Cells and Neutrophils by Daria Augustyniak, Justyna Roszkowiak, Izabela Wiśniewska, Jacek Skała, Daiva Gorczyca, Zuzanna Drulis-Kawa

“…Concluding, these findings suggest that SP and CGRP mediate the dampening of proinflammatory action triggered by M. catarrhalis OMVs towards cells engaged in lung inflammation in vitro.…”
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Targeted allele-specific FGFR2 knockdown via human recombinant ferritin nanoparticles for personalized treatment of Crouzon syndrome by Federica Tiberio, Martina Salvati, Luca Polito, Giada Tisci, Alessia Vita, Ornella Parolini, Luca Massimi, Lorena Di Pietro, Pierpaolo Ceci, Gianpiero Tamburrini, Alessandro Arcovito, Elisabetta Falvo, Wanda Lattanzi

“…Here, we show that ferritin-mediated AS FGFR2 knockdown by siRNA represents a suitable strategy to dampen FGFR2 overactivation in patients’ cells.…”
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Selective Immunomodulation of Inflammatory Pathways in Keratinocytes by the Janus Kinase (JAK) Inhibitor Tofacitinib: Implications for the Employment of JAK-Targeting Drugs in Psor... by Martina Morelli, Claudia Scarponi, Laura Mercurio, Francesco Facchiano, Sabatino Pallotta, Stefania Madonna, Giampiero Girolomoni, Cristina Albanesi

“…To limit the detrimental consequences of IFN-γ and IL-22 excessive stimulation, psoriatic keratinocytes activate suppressor of cytokine signaling (SOCS)1 and SOCS3, which in turn dampen molecular signaling by inhibiting JAK1 and JAK2. …”
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SQM Ageing and Atmospheric Conditions: How Do They Affect the Long-Term Trend of Night Sky Brightness Measurements? by Pietro Fiorentin, Stefano Cavazzani, Andrea Bertolo, Sergio Ortolani, Renata Binotto, Ivo Saviane

“…The comparison among the daily irradiance increase, the reduction in the aerosol optical depth, and the NSB measurements highlighted a darker sky for sites contaminated by light pollution (LP) and a brighter sky for sites not affected by LP, showing a significant and predominant role of atmospheric conditions in relation to NSB change. …”
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The interplay of perceived benefit, perceived risk, and trust in Fintech adoption: Insights from Sub-Saharan Africa by Thomas Appiah, Veronica Venyo Agblewornu

“…Furthermore, the findings provide support for the mediation model, suggesting that trust dampens the negative effect of perceived risk on Fintech adoption. …”
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The potential impact of glycine supplementation on the process of aging by Michalina Wójcikiewicz, Julia Kulbacka, Witold Czyż, Julia Kacperczyk, Karol Dziedzic, Marta Chuncia-Ileczko, Maciej Wojszczyk, Damian Zys, Piotr Pasek, Julia Ryniecka, Wiktor Czaja, Michał Krzciuk

“…Emerging studies suggest that glycine supplementation may alleviate oxidative stress, dampen chronic low-grade inflammation, improve insulin sensitivity, enhance mitochondrial function, and even mimic aspects of methionine restriction- a dietary approach known to extend lifespan in animal models. …”
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Role of the androgen receptor in melanoma aggressiveness by Marzia Di Donato, Costanza Maria Cristiani, Mariaelena Capone, Cinzia Garofalo, Gabriele Madonna, Lucia Carmela Passacatini, Margaret Ottaviano, Paolo Antonio Ascierto, Ferdinando Auricchio, Ennio Carbone, Antimo Migliaccio, Gabriella Castoria

“…At last, melanoma cells depleted of the androgen receptor become more responsive to the most commonly used immunocheckpoint inhibitors, suggesting that the receptor dampens the immunotherapy efficacy. Taken together, our findings identify the androgen receptor as a diagnostic guidance in melanoma and support the repositioning of AR blockers in clinical management of patients.…”
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Textural, Color, and Sensory Analysis of Cookies Prepared with Hemp Oil-Based Oleogels by Ana Leahu, Cristina Ghinea, Sorina Ropciuc, Cristina Damian

“…The color of the oleogel cookies was darker than that of the control cookies. The cookie sample with hemp oil and beeswax oleogel was the most appreciated by the evaluators among the oleogel cookie samples. …”
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