Expression and Clinical Significance of DAP3 in Breast Cancer and Effect of Bruceine D on Expression of DAP3:Analysis Based on Data-mining from Bioinformatics by Wenlong WANG, Qingzhi KONG, Hongda LU, Qingdong XIANG, Dianlei LIU

“…In addition, CCLE database analysis indicated that DAP3 was also highly expressed in breast cancer cell lines and its mRNA expression ranked ahead in all kinds of cancer cell lines. Finally, Bruceine D can down-regulate the DAP3 gene expression in breast cancer cells, which was found by analyzing the datasets of GSE85871 in the GEO database(<italic>P</italic>&lt;0.05).Conclusion:DAP3 gene is high-expressed in breast cancer and its expressionlevel is closely associated with the prognosis of breast cancer patients, which may be a new intervening target of Bruceine D on breast cancer cells.…”
Get full text

Bacterial Isolates and Their Antimicrobial Susceptibility Patterns Among Pediatric Patients with Urinary Tract Infections: A Retrospective Cross-Sectional Study at Tertiary Level i... by Esmat E, Saadaat R, Saedi NH, Hakimi A, Baryali AT, Rasooli AJ, Noor S, Ahmad M, Haidary AM

“…Esmatullah Esmat,1 Ramin Saadaat,1 Noor Hassan Saedi,1 Ahmadullah Hakimi,1 Abdul Tawab Baryali,2 Abdul Jamil Rasooli,3 Sahar Noor,3 Maryam Ahmad,1 Ahmed Maseh Haidary1 1Department of Pathology and Clinical Laboratory, French Medical Institute for Mother and Children (FMIC), Kabul, Afghanistan; 2Department of Quality and Patient Safety, French Medical Institute for Mothers and Children (FMIC), Kabul, Afghanistan; 3Department of Paediatric Medicine, French Medical Institute for Mother and Children (FMIC), Kabul, AfghanistanCorrespondence: Ahmed Maseh Haidary, Department of Pathology and Clinical Laboratory, French Medical Institute for Mother and Children (FMIC), Behind Kabul Medical University, Kabul, PO, BOX:472, Afghanistan, Email ahmed.maseh9t9@gmail.comIntroduction: The widespread use of antibiotics is a serious and alarming situation in terms of the development of antimicrobial resistance. …”
Get full text

Explainable AI in Diagnostic Radiology for Neurological Disorders: A Systematic Review, and What Doctors Think About It by Yasir Hafeez, Khuhed Memon, Maged S. AL-Quraishi, Norashikin Yahya, Sami Elferik, Syed Saad Azhar Ali

“…We also present medical domain experts’ opinions and summarize the challenges up ahead that need to be addressed in order to fully exploit the tremendous potential of XAI in its application to medical diagnostics and serve humanity. …”
Get full text

Light People: Prof. Henry Snaith’s (FRS) perovskite optoelectronics journey by Ruidong Xia, Ying Hu

“…When asked about the potential for a Nobel Prize, Henry acknowledged that PSC technology could be worthy of such recognition, given its scientific advancements and significant contributions to addressing the global challenge of climate change. Looking ahead, Henry has expressed an interest in contributing to public policy, particularly in the areas of renewable energy and education reform, with an emphasis on the creation of an inclusive education system that better supports neurodiversity.…”
Get full text

A Randomized, Placebo-Controlled, Single-Center, Crossover Study to Evaluate the Effects of Pre-Meal Whey Protein Microgel on Post-Prandial Glucometabolic and Amino Acid Response i... by Ian J Neeland, Luiz H de Gregório, Roberto Zagury, Bo Ahrén, Joel Neutel, Christian Darimont, John Corthesy, Yohan Grzywinski, Emilie Perrin, Maximilian von Eynatten, Odd Erik Johansen

“…After an overnight fast and a standardized breakfast, 10 g (125 mL) WPM (40 kcal) or placebo (125 mL water, 0 kcal) was consumed 15 min ahead of the mixed-nutrient meal. Effects on PPG (primary endpoint), insulin, GLP-1, and branched-chain amino acids (BCAAs) were evaluated with frequent blood sampling. …”
Get full text

Türkiye’de Seçim İttifakları: 1950-2018 by Aslıhan Çoban Balcı, Özhan Demirkol

“…Büyük partiler ise cumhurbaşkanlığı seçimlerinde adaylarının ilk turda seçilme ihtimalini arttırmak için ortak sayısını arttırmaya ve küçük partilerin yanı sıra mikro partilerle de ortaklık kurmaya başlamışlardır. Dahası, büyük partiler ideolojik olarak farklı partilerle de ortaklığın kapısını aralamış ve ilk defa iktidardaki bir parti muhalefette olan küçük ve mikro partilerle ittifaklara yönelmiştir.…”
Get full text

6 Şubat Depremi Sonrasında Manevi Danışmanlık Hizmetleri: Kırşehir Örneği by Suzan Yıldırım

“…Bir kamu kurumu olan Diyanet İşleri Başkanlığı’na (DİB) bağlı İl ve İlçe Müftülükleri personeli, merkez teşkilatı ve Diyanet Vakfı çalışanları da sahada görev yapmıştır. DİB personelinin deprem bölgesinde manevi danışman olarak hizmet vermesi, o tarihlerde, bazı kesimler tarafından eleştirilmiştir. …”
Get full text

Automatic Recognition of Authors Identity in Persian based on Systemic Functional Grammar by Fatemeh Soltanzadeh, Azadeh Mirzaei, Mohammad Bahrani, Shahram Modarres Khiabani

“…Method A corpus was compiled from the works of seven contemporary Persian writers: Hoshang Golshiri, Bozorg Alavi, Ahmad Mahmoud, Mahmoud Dolatabadi, Nader Ebrahimi, Jalal Al-e Ahmad, and Gholamhossein Saedi, totaling 2,069,243 words. …”
Get full text

Reasons Why Patients Do Not Return to Sport Post ACLReconstruction: A Cross-Sectional Study by Hamdan M, Haddad BI, Amireh S, Abdel Rahman AMA, Almajali H, Mesmar H, Naum C, Alqawasmi MS, Albandi AM, Alshrouf MA

“…Mohammad Hamdan,1 Bassem I Haddad,1 Saadat Amireh,2 Anas Mohammad Ahmad Abdel Rahman,2 Hala Almajali,2 Hazim Mesmar,2 Christina Naum,2 Mahmmud Sameer Alqawasmi,1 Alaa M Albandi,2 Mohammad Ali Alshrouf2,3 1Department of Special Surgery, Division of Orthopedics, School of Medicine, The University of Jordan, Amman, 11942, Jordan; 2School of Medicine, The University of Jordan, Amman, 11942, Jordan; 3Special Accident and Joint Surgery, Sportklinik Hellersen, Lüdenscheid, 58515, GermanyCorrespondence: Mohammad Ali Alshrouf, Special Accident and Joint Surgery, Sportklinik Hellersen, Paulmannshöher Street 17, Lüdenscheid, 58515, Germany, Tel +491622462460, Email M.Alshrouf@outlook.comBackground: Patients who incur an anterior cruciate ligament (ACL) injury and undergo ACL reconstruction (ACLR) have the intention of returning to sports at their pre-injury level; however, many do not return to the pre-injury level. …”
Get full text

The Lived Experience of Adult Cancer Survivors After Hematopoietic Stem Cell Transplantation: A Qualitative Study From Saudi Arabia by Almutairi H, Aboshaiqah A, Alzahrani M, Almutairi AF, Salam M

“…Hamdan Almutairi,1,2 Ahmad Aboshaiqah,2 Mohsen Alzahrani,3 Adel F Almutairi,4 Mahmoud Salam5 1Transfusion Medicine Services, Department of Pathology and Laboratory Medicine, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia; 2College of Nursing, King Saud University, Riyadh, Saudi Arabia; 3Division of Hematology and Stem Cell Transplant, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia; 4King Abdullah International Medical Research Center, Riyadh, Saudi Arabia, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia; 5Alice Ramez Chagoury School of Nursing, Lebanese American University, Byblos, LebanonCorrespondence: Hamdan Almutairi, Transfusion Medicine Services, Department of Pathology and Laboratory Medicine, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia, Tel +966503414140, Email MotairiH@mngha.med.sa Mahmoud Salam, Alice Ramez Chagoury School of Nursing, Lebanese American University, Byblos, Lebanon, Tel +96170054397, Email mahmoud.salam@lau.edu.lbBackground: Hematopoietic stem cell transplantation (HSCT) is a high-intensity treatment with the potential to extend the life expectancy of some patients with cancer. …”
Get full text

Hubungan Pelaksanaan Strategi Directly Observed Treatment Short Course dengan Hasil Pengobatan Tuberkulosis Paru Puskesmas Padang Pasir Kota Padang 2011-2013 by Nurmadya ., Irvan Medison, Hafni Bachtiar

“…Hasil uji statistik Chi-Square menunjukkan adanya hubungan antara pelaksanaan komitmen oleh petugas kesehatan (p-value : 0,000), pelaksanaan pemeriksaan dahak (p-value: 0,005, ketersedian OAT (p-value : 0,002) dengan hasil pengobatan TB paru. …”
Get full text

Tr ansatlantic Trade and Investment Partnership: Consigned to Oblivion or Waiting for a Second Chance? by A. О. Mamedova

“…These unilateral measures turned into leverage ahead of negotiations. In June 2018 the U.S. and the EU issued a Joint Statement: the parties agreed to ‘work together toward zero tariffs, zero non-tariff barriers, and zero subsidies on non-auto industrial goods.’ …”
Get full text

Mu‘tezilî Âlim Kâdî Abdülcebbâr Şâfiî miydi? by Bahaddin Karakuş, Ahmet Yaman

“…Abdülcebbâr’ın usûl görüşlerini İmam Şâfiî’nin usûl görüşleriyle mukayese ederek ilerleyen işbu araştırma, onun amelî sahada Şâfiî mezhebini benimsemiş olduğu iddiasının çok isabetli olmadığı sonucuna ulaşmıştır. …”
Get full text

Muՙtezilî Usûlcülerin Mecaz Tanımları Üzerine Bir Değerlendirme by Yasin Akan

“… Dini sahada tartışılan bazı kavramlar birden fazla disipline konu olmuş ve bu kavramlar her disiplinde farklı açılardan ele alınmıştır. …”
Get full text

Gazzâlî’nin Mûcizeye Yaklaşımının Tehâfütü’l-Felâsife Bağlamında Kuantum Kuramı Açısından Değerlendirilmesi by Ahmet Çelik, Ayşe Kocabaş

“…Klasik fizik anlayışını değiştiren kuantum kuramı, bilimsel sahada ilk defa ortaya çıkan indeterminizm olması bakımından felsefe ve teoloji alanlarında da büyük etkiler meydana getirmiştir. …”
Get full text

Kırâat İlmine Olan Teveccühün Azalması Üzerine Hocazâde Ahmed Hilmi’nin Cerîde-i Sûfiyye’de Kaleme Aldığı ‘Ravzatü’l-Kurrâ’ İsimli Makalelerinin Neşri by Yaşar Akaslan

“…Bu çerçevede kırâat ilmi en parlak dönemlerinden birisini Osmanlı coğrafyasında yaşamıştır. Sahada yetişen mütehassıs âlimler, kaleme alınan pek çok mufassal ve muhtasar eser, kırâat tedris birikiminin bir neticesi olarak tesis edilen ekoller kırâat tarihinin konuları arasına girmekle kalmamış, İslâm ilim tarihinin önemli bir bölümünü oluşturmuştur. …”
Get full text

Esbâb-ı Nüzûl'de Hz. Hamza by Ahmet Gündüz

“…Doğru ve kapsamlı bir sonuca ulaşmak için Vâhidî’nin eserinin yanı sıra, aynı sahada farklı eserlere de müracaat edilmiştir. Bunun için aynı metotla Suyûti’nin Lübâbü’n-nükûl adlı eseri ile İbn Hacer’in el-‘Ucâb fî beyâni’l-esbâb adlı telifleri gözden geçirilmiştir. …”
Get full text

Mu‘tezile’de Aklî Teklif by Yunus Eraslan

“…Bir diğer mesele ise Mu‘tezile değerlerin tayin ve tespitinde akla birincil, vahye ise ikincil rol yüklediğine göre, aklın vahiyden bağımsız olarak insanlara bir sorumluluk yükleme yetkinliği var mıdır? Dahası bu sorumluluğun neticesinde akıl sahipleri için ceza ve mükâfat söz konusu olacak mıdır? …”
Get full text

Nahiv İlminin Güncel Anlatımında Modern Dilbilim Yaklaşımlarının Etkisi: et-Taṭbîḳu’n-naḥvî Örneği by Esma Sağ Şencal

“…Böylece Râciḥî, güncel dil kullanımlarına yer vererek ve dahası dil toplumu tarafından kullanım sıklıklarına dikkat ederek çağdaş fasih Arapçadaki değişimin farkında olduğunu ve nahiv kurallarının hala geçerli olduğunu okuyucuya göstermektedir. …”
Get full text

Editorial by Editor

“…Wishing you a wonderful year ahead! …”
Get full text