Acquired sperm hypomethylation by gestational arsenic exposure is re-established in both the paternal and maternal genomes of post-epigenetic reprogramming embryos by Keiko Nohara, Takehiro Suzuki, Kazuyuki Okamura, Tomoko Kawai, Kazuhiko Nakabayashi

“…Abstract Background DNA methylation plays a crucial role in mammalian development. …”
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The ichthyofauna of the upper Neretva River by Jakob Neuburg, Thomas Friedrich, Elisabeth Haring, Sarah Höfler, Ana Maric, Saša Marić, Stephanie Popp, Predrag Simonović, Aleš Snoj, Simona Sušnik Bajec, Simon Vitecek, Alexandra Wanka, Steven Weiss, Kurt Pinter

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Rare Taxa Are Key Links in Regional Antimicrobial Resistance Profiles in Dusts Across Diverse North American Regions by Paul B. L. George, Florent Rossi, Marc Veillette, Amélia Bélanger Cayouette, Samantha Leclerc, Cindy Dumais, Nathalie Turgeon, Caroline Duchaine

“…In addition, bioaerosols are powerful composite samples representative of the surrounding environment and can be used as sentinels of many local habitats. Evidence suggests that using environmental DNA from dust collected on vehicle cabin air filters can define regional resistance profiles. …”
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Comparative Genomics Reveals Evidence of the Genome Reduction and Metabolic Potentials of <i>Aliineobacillus hadale</i> Isolated from Challenger Deep Sediment of the Mariana Trench by Shaofeng Yang, Jie Liu, Yang Liu, Weichao Wu, Jiahua Wang, Yuli Wei

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Uncovering Diversity within the Glomeromycota: Novel Clades, Family Distributions, and Land Use Sensitivity by Camille S. Delavaux, Alexis Aellen, Sidney L. Stürmer, Silmar Primieri, Ursel M. E. Schütte, Devin M. Drown, Robert J. Ramos, Thomas W. Crowther, James D. Bever

“…Using a recently developed pipeline for phylogenetic placement of eDNA, we find evidence for three putative novel clades within the Glomeromycota, sister to Entrophosporaceae, Glomeraceae, and Archaeosporaceae, with evidence for geographic structuring. …”
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Association of hepatitis B virus DNA levels with efficacy and safety and the impact of antiviral therapy on prognosis in liver cancer patients receiving immune checkpoint inhibitor... by Hongxia Cui, Su Li, Wu Lv, Jing Xiang

“…BackgroundThe current evidence regarding the relationship between baseline hepatitis B virus (HBV) DNA levels and survival outcomes in liver cancer patients receiving immune checkpoint inhibitors (ICIs) remains inconsistent. …”
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Timing of dietary effects on the epigenome and their potential protective effects against toxins by Lynnea A. Nicholls, Kendall A. Zeile, London D. Scotto, Rebecca J. Ryznar

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The Impact of Modifiable Risk Factors on the Endothelial Cell Methylome and Cardiovascular Disease Development by Hashum Sum, Alison C. Brewer

“…Thus, it is speculated that changes in DNA methylation within endothelial cells may, in part, be causal in ED, leading to atherosclerosis and CVD generally. …”
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Enhancing epigenetic aging clocks in cetaceans: accurate age estimations in small endangered delphinids, killer whales, pilot whales, belugas, humpbacks, and bowhead whales by Joseph A. Zoller, Ake T. Lu, Amin Haghani, Steve Horvath, Todd Robeck

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Multi-omics analysis reveals novel causal pathways in psoriasis pathogenesis by Hua Guo, Jinyang Gao, Liping Gong, Yanqing Wang

“…Results Our analyses identified significant causal associations between DNA methylation, gene expression, protein abundance, and psoriasis risk. …”
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Real-world enrollment for a prospective clinico-genomic database using a pragmatic technology-enabled platform by Alexia Exarchos, Ariel B. Bourla, Maneet Kaur, Katja Schulze, Sophia Maund, Yi Cao, Yihua Zhao, Elizabeth H. Williams, Sarah C. Gaffey, Richard Zuniga, Shaily Lakhanpal, Vladan Antic, Michelle Doral, Johanna Sy, Neal J. Meropol, Anne C. Chiang

“…Serial blood samples at pre-specified timepoints (baseline, during treatment and at disease progression/end of therapy) were used for circulating tumor DNA (ctDNA) genomic profiling. Results: Between December 2019 and May 2021, 944 patients enrolled, representing ≈25 % of eligible patients. …”
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Epigenetic regulation in coronary artery disease: from mechanisms to emerging therapies by Rui Gao, Rui Gao, Rui Gao, Meilin Liu, Meilin Liu, Meilin Liu, Haoyi Yang, Haoyi Yang, Haoyi Yang, Yuhan Shen, Yuhan Shen, Yuhan Shen, Ni Xia, Ni Xia, Ni Xia

“…Epigenetics is a field investigating heritable alterations in gene expression without DNA sequence changes, such as DNA methylation, histone modifications, and non-coding RNAs. …”
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Greater residential greenness is associated with reduced epigenetic aging in adults by Andrey I. Egorov, Shannon M. Griffin, Jo Klein, Wei Guo, Jennifer N. Styles, Jason Kobylanski, Mark S. Murphy, Elizabeth Sams, Edward E. Hudgens, Timothy J. Wade

“…Epigenetic age acceleration (EAA) is a composite biomarker of biological aging based on DNA methylation measurements; it is predictive of morbidity and mortality. …”
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Molecular Data Confirm the Occurrence of the Allochthonous <i>Gambusia holbrooki</i> (Pisces: Poeciliidae) in Sicily and the Maltese Archipelago by Luca Vecchioni, Mirko Liuzzo, Arnold Sciberras, Jeffrey Sciberras, Justin Formosa, Alan Deidun, Gabriele Giacalone, Vincenzo Arizza, Marco Arculeo, Federico Marrone, Francesco Paolo Faraone

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PCR-based detection of Botryosphaeria canker pathogens in fig trees by Mahdiyeh Ghaedi, Zeinab Bolboli, Hamed Negahban, Reza Mostowfizadeh-Ghalamfarsa

“…Moreover, multiplex PCR enabled simultaneous DNA detection of the target Botryosphaeriaceae pathogens. …”
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Temperature-dependent toxicity and mechanisms of florfenicol on the embryonic development of marine medaka (Oryzias melastigma) by Xingying Guo, Xu Gong, Jinhui Wang, Tan-Duc Nguyen, Syed Shabi Ul Hassan Kazmi, Jiezhang Mo, Feng Hua, Wenhua Liu, Zhen Wang

“…Conversely, gene upregulation was also observed for all treatments at 30 °C, while predominantly downregulation was observed for all treatments at 20 °C. For genes related to DNA damage and apoptosis (pi3k, akt, foxo1, tp53, bcl-2, bax, apaf-1, caspase 9, and 3), alterations in gene expression were evident for all florfenicol treatments at both 20 °C and 30 °C. …”
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Inhibition of miMOMP-induced SASP to combat age-related disease by Xiaoli Liao, Zhennan Guo, Zhennan Guo, Mouhai He, Yichun Zhang

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Targeted detection of endogenous LINE-1 proteins and ORF2p interactions by Mathias I. Nielsen, Justina C. Wolters, Omar G. Rosas Bringas, Hua Jiang, Luciano H. Di Stefano, Mehrnoosh Oghbaie, Samira Hozeifi, Mats J. Nitert, Alienke van Pijkeren, Marieke Smit, Lars ter Morsche, Apostolos Mourtzinos, Vikram Deshpande, Martin S. Taylor, Brian T. Chait, John LaCava

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Forensic technology: concepts, objectives and principles by V. M. Kyselov

“…The article establishes that the key tasks of forensic technology are as follows: collecting, recording and documenting physical evidence at the crime scene; analysing the collected evidence, including photo and video materials, audio recordings, DNA samples, fingerprints, etc.; examining physical evidence to prove its relevance to the crime and connection with the suspect or accused; creating a reconstruction of events to understand the course of the crime and prove the guilt of the suspect or accused; preparing expert reports and testimony for use in court proceedings; supporting investigators and prosecutors in the use of scientific methods and techniques to collect and analyse evidence; conducting research and improving forensic techniques to improve law enforcement and increase the effectiveness of crime investigations. …”
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Interplay between Epigenetics and Genetics in Cancer by Jae Duk Choi, Jong-Soo Lee

“…Mechanisms involve both genomic instability and epigenomic aberrations that lose or gain the function of genes that impinge on tumor suppression/prevention or oncogenesis. Growing evidence points to an epigenome-wide disruption that involves large-scale DNA hypomethylation but specific hypermethylation of tumor suppressor genes, large blocks of aberrant histone modifications, and abnormal miRNA expression profile. …”
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