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Topical Mitomycin C and Radiation Induce Conjunctival DNA-Polyploidy
Published 2001-01-01“…In five cases image cytometry additionally demonstrated DNA‐stemline aneuploidy as an evidence of tumor recurrence. …”
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22
Conjugates of Phthalocyanines With Oligonucleotides as Reagents for Sensitized or Catalytic DNA Modification
Published 2006-01-01“…<p>Several conjugates of metallophthalocyanines with deoxyribooligonucleotides were synthesized to investigate sequence-specific modification of DNA by them. Oligonucleotide parts of these conjugates were responsible for the recognition of selected complementary sequences on the DNA target. …”
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23
Metazoan diversity in Chilean hypersaline lakes unveiled by environmental DNA
Published 2025-01-01“…Overall, this study provides evidence that eDNA is an effective tool to elucidate fine scale taxa assemblages and can refine conservation efforts in hypersaline lakes.…”
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24
Immunogenicity of RSV F DNA Vaccine in BALB/c Mice
Published 2016-01-01“…Our data evidently showed that the RSV F DNA vaccine activated the Th1 biased immune response and led to the production of neutralizing antibodies, which is the desired immune response required for protection from RSV infections.…”
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25
Re-evaluating evidence for giant genomes in amoebae
Published 2024-12-01“…Traditionally, estimates relied on inaccurate methods like DNA weight measurements, leading to inflated sizes. …”
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26
Decoding mitochondrial DNA damage and repair associated with H. pylori infection
Published 2025-01-01“…In this review, we summarize the molecular mechanisms of spontaneous and H. pylori infection-associated oxidative mtDNA damage, mtDNA replication stress, and its impact on innate immune signaling. …”
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27
Non-B DNA Secondary Structures and Their Resolution by RecQ Helicases
Published 2011-01-01“…Such secondary structures have a range of biological functions but also induce genetic instability. Increasing evidence suggests that genomic instabilities induced by non-B DNA secondary structures result in predisposition to diseases. …”
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28
Anticancer, Antibacterial, Antioxidant, and DNA-Binding Study of Metal-Phenalenyl Complexes
Published 2022-01-01“…Experimental evidence revealed that the complexes bind to DNA through intercalation, and the molecular docking study supported this conclusion.…”
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29
D-2-hydroxyglutarate impairs DNA repair through epigenetic reprogramming
Published 2025-02-01“…These findings provide evidence that CTCF-mediated chromatin interactions play a key role in DNA damage repair proceedings. …”
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30
Age-related changes in DNA methylation in a sample of elderly Brazilians
Published 2025-02-01“…Abstract Background Age-related changes in DNA methylation (DNAm) play a critical role in regulating gene expression. …”
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31
Increased DNA Copy Number Variation Mosaicism in Elderly Human Brain
Published 2018-01-01“…Previous reports have shown that the genome of neuronal cells displays somatic genomic mosaicism including DNA copy number variations (CNVs). CNVs represent a significant source of genetic variation in the human genome and have been implicated in several disorders and complex traits, representing a potential mechanism that contributes to neuronal diversity and the etiology of several neurological diseases and provides new insights into the normal, complex functions of the brain. …”
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32
Diagnostic impact of DNA methylation classification in adult and pediatric CNS tumors
Published 2025-01-01“…The aim of this study is to share our experience using DNA methylation classification in daily routine practice, illustrated through clinical cases. …”
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33
Synthetic genomics in crop breeding: Evidence, opportunities and challenges
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34
Environmental DNA profiling for detecting plant-insect interactions in endangered and native flora
Published 2025-01-01“…This study provides important evidence of the effectiveness of eDNA for studying flower-visiting insects, proving its ability to provide a comprehensive overview of pollinator communities beyond traditional observational methods. …”
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35
Interactions of Neanderthals and Modern Humans: What Can Be Inferred from Mitochondrial DNA?
Published 2005-07-01“…The branching-process method is applied to infer the upper limit of hypothetical Neanderthal admixture, consistent with the evidence based on mitochondrial DNA sequences of contemporary modern humans, as well as Neanderthal and early modern European H. sapiens fossils. …”
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36
DNA methylation and its influence on the pathogenesis of osteoarthritis: a systematic literature review
Published 2025-02-01“…Purpose: Evolving evidence demonstrates the role of epigenetics in the pathogenesis of osteoarthritis (OA), whereas in terms of mechanism, DNA methylation has received the highest attention thus far. …”
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Comparative (Computational) Analysis of the DNA Methylation Status of Trinucleotide Repeat Expansion Diseases
Published 2013-01-01“…Furthermore, comparing our software with MEME software, we have demonstrated that our software identifies more patterns than MEME in these short DNA sequences. Thus, we present evidence that the DNA sequence surrounding CpG can influence its susceptibility to be de novo methylated in a disease state associated with a trinucleotide repeat.…”
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38
SSR analysis of the genomic DNA of perspective Uzbek hexaploid winter wheat varieties
Published 2018-09-01“…Microsatellite markers are now most widely used and effective classes of DNA markers for genotyping, certification and classification of plant varieties. …”
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Absence of MCJ/DnaJC15 promotes brown adipose tissue thermogenesis
Published 2025-01-01“…This study describes the role of the mitochondrial protein Methylation-controlled J protein (MCJ/DnaJC15) in orchestrating brown adipose tissue (BAT) thermogenesis. …”
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40
Epigenetics and Inflammatory Markers: A Systematic Review of the Current Evidence
Published 2019-01-01“…Therefore, we aimed to systematically review studies investigating the association between DNA methylation and histone modifications with circulatory inflammation markers in blood. …”
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