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Identification of the Genomics and Transcriptomics Regulators of the DNA Damage Response in Breast Cancer
Published 2024-02-01Get full text
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New Turns for High Efficiency Knock-In of Large DNA in Human Pluripotent Stem Cells
Published 2018-01-01Get full text
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The Dynamic DNA Demethylation during Postnatal Neuronal Development and Neural Stem Cell Differentiation
Published 2018-01-01Get full text
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Mapping neutron biological effectiveness for DNA damage induction as a function of incident energy and depth in a human sized phantom
Published 2025-01-01“…Abstract We present new developments for an ab-initio model of the neutron relative biological effectiveness (RBE) in inducing specific classes of DNA damage. …”
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COMPUTATIONAL SCREENING TO IDENTIFY GENES INVOLVED IN DNA REPAIR IN ARABIDOPSIS THALIANA
Published 2024-12-01Get full text
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Analysing DNA methylation and transcriptomic signatures to predict prostate cancer recurrence risk
Published 2025-02-01“…Validation using real-time PCR confirmed differential expression and methylation patterns of the identified genes in prostate cancer (PC3) and non-cancerous cell lines (PNT2). In conclusion, our study hihglights the DNA methylation biomarkers linked to PCa recurrence and introduces a promising SVM model for early prediction, potentially improving treatment outcomes. …”
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Correlation among blastocoel fluid DNA level, apoptotic genes expression and preimplantation aneuploidy
Published 2025-02-01Get full text
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Versatile Click Chemistry-based Approaches to Illuminate DNA and RNA G-Quadruplexes in Human Cells
Published 2025-02-01“…The existence and functional relevance of DNA and RNA G-quadruplexes (G4s) in human cells is now beyond debate, but how did we reach such a level of confidence? …”
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Cancer Stem Cells from Tumor Cell Lines Activate the DNA Damage Response Pathway after Ionizing Radiation More Efficiently Than Noncancer Stem Cells
Published 2019-01-01“…CSC are proposed to repair DNA damage more efficiently than the rest of tumor cells, resisting chemotherapy or radiotherapy and causing clinical recurrence and metastasis. …”
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Diagnostics of lung cancer by fragmentated blood circulating cell-free DNA based on machine learning methods
Published 2025-01-01“…The blood plasma circulating cell-free DNA (cfDNA) fragments reflect the genome and chromatin status and are considered as integral cancer biomarkers and the biological entities for ‘cancer-of-origin’ prediction. …”
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N6-Methyladenosine in RNA and DNA: An Epitranscriptomic and Epigenetic Player Implicated in Determination of Stem Cell Fate
Published 2018-01-01“…This review article will highlight the research advances in the role of m6A methylation modifications of DNA and RNA in the regulation of stem cell and genesis of the closely related disorders. …”
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DNA Methylation Is Involved in the Expression of miR-142-3p in Fibroblasts and Induced Pluripotent Stem Cells
Published 2014-01-01“…MicroRNAs are differentially expressed in cells and regulate multiple biological processes. …”
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Restriction Enzyme Analysis of DNA Methylation in “Condensed” Chromatin of Ha-Ras-Transformed NIH 3T3 Cells
Published 2000-01-01Get full text
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DNA hypomethylation-mediated upregulation of GADD45B facilitates airway inflammation and epithelial cell senescence in COPD
Published 2025-02-01“…Accelerated lung aging and inflammation mutually reinforce each other, creating a detrimental cycle that contributes to disease progression. Growth arrest and DNA damage-inducible (GADD45) family has been reported to involve in multiple biological processes, including inflammation and senescence. …”
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