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miR-142 deficit in T cells during blast crisis promotes chronic myeloid leukemia immune escape
Published 2025-02-01Get full text
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Bcl2 Family Functions as Signaling Target in Nicotine-/NNK-Induced Survival of Human Lung Cancer Cells
Published 2014-01-01Get full text
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Chromosome-level reference genome assembly for the mountain hare (Lepus timidus)
Published 2025-01-01Get full text
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The Role of Epigenetic in Dental and Oral Regenerative Medicine by Different Types of Dental Stem Cells: A Comprehensive Overview
Published 2022-01-01“…Several lines of evidence have shown that epigenetic modification of DNA and DNA-correlated histones are necessary for determining cells’ phenotypes and regulating stem cells’ pluripotency and renewal capacity. …”
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The Critical Role of Bach2 in Shaping the Balance between CD4+ T Cell Subsets in Immune-Mediated Diseases
Published 2019-01-01“…Here, we reveal a critical role of Bach2 in regulating T cell biology and the correlation with these immune-mediated diseases.…”
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Practical techniques in molecular biotechnology /
Published 2021Table of Contents: “…Recombinant DNA and protein technology -- Enzyme kinetics, proteomics and mass spectrometry -- Bioanalytical techniques -- Molecular biology -- Cell culture -- Antibody technology.…”
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Ubiquitination Enzymes in Cancer, Cancer Immune Evasion, and Potential Therapeutic Opportunities
Published 2025-01-01“…The ubiquitin–proteasome system (UPS) is critical in maintaining essential life processes such as cell cycle control, DNA damage repair, and apoptosis. …”
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Evaluating H2BC9 as a potential diagnostic and prognostic biomarker in head and neck squamous cell carcinoma
Published 2025-01-01“…Silencing H2BC9 suppressed cell proliferation, induced G2/M cell cycle arrest, and enhanced apoptosis and DNA damage in HNSCC cells. …”
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Epigenetic Mechanisms in Type-2 Diabetes Mellitus: A Narrative Review
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Gastric Cancer Cell Lines Have Different MYC-Regulated Expression Patterns but Share a Common Core of Altered Genes
Published 2018-01-01“…We were able to detect 11 significant gene sets when comparing our samples to the hallmark collection of gene expression, enriched mostly for the following hallmarks: proliferation, pathway, signaling, metabolic, and DNA damage response. When we analyzed our DEGs considering KEGG metabolic pathways, we found 12 common branches covering a wide range of biological functions, and three of them were common to all three cell lines: ubiquitin-mediated proteolysis, ribosomes, and system and epithelial cell signaling in Helicobacter pylori infection. …”
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CRISPR/Cas9, a universal tool for genomic engineering
Published 2016-09-01“…First, we describe the basic mechanism of the CRISPR/Cas9 DNA recognition and binding, focusing in particular on its off-target activity. …”
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