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Protocol for the quantitative detection of mtDNA in the supernatants of activated human naive CD8+ T cells
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Lipid nanoparticles deliver DNA-encoded biologics and induce potent protective immunity
Published 2025-01-01“…Abstract Lipid nanoparticles (LNPs) for mRNA delivery have advanced significantly, but LNP-mediated DNA delivery still faces clinical challenges. This study compared various LNP formulations for delivering DNA-encoded biologics, assessing their expression efficacy and the protective immunity generated by LNP-encapsulated DNA in different models. …”
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Mathematical analysis and modeling of DNA segregation mechanisms
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The concept of natural genome reconstruction. Part 1. Basic provisions of the “natural genome reconstruction” concept. Changing the genome of hematopoietic stem cells using several...
Published 2024-11-01“…We present a series of articles proving the existence of a previously unknown mechanism of interaction between hematopoietic stem cells and extracellular double-stranded DNA (and, in particular, double-stranded DNA of the peripheral bloodstream), which explains the possibility of emergence and fixation of genetic information contained in double-stranded DNA of extracellular origin in hematopoietic stem cells. …”
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Protocol for the purification and analysis of nuclear UFMylated proteins
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DNA Methylation in Skeletal Muscle Stem Cell Specification, Proliferation, and Differentiation
Published 2016-01-01“…An unresolved and critically important question in skeletal muscle biology is how muscle stem cells initiate and regulate the genetic program during muscle development. …”
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Synergistic effect of inhibiting CHK2 and DNA replication on cancer cell growth
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Association of Self-DNA Mediated TLR9-Related Gene, DNA Methyltransferase, and Cytokeratin Protein Expression Alterations in HT29-Cells to DNA Fragment Length and Methylation Statu...
Published 2013-01-01“…To understand the biologic role of self-DNA bound to Toll-like Receptor 9 (TLR9), we assayed its effect on gene and methyltransferase expressions and cell differentiation in HT29 cells. …”
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Uptake of Single-Walled Carbon Nanotubes Conjugated with DNA by Microvascular Endothelial Cells
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Challenges in observing transcription–translation for bottom-up synthetic biology
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Cell-free DNA release following psychosocial and physical stress in women and men
Published 2025-01-01“…However, further research is necessary to elucidate the mechanisms of cfDNA release from specific cells and to understand its biological function in the body.…”
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The enigma of cancer polyploidy as deciphered by evolutionary cancer cell biology (ECCB)
Published 2024-06-01“… Evolutionary cancer cell biology reveals that the majority of cancer hallmarks trace their origins back to the premetazoic era. …”
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Modulation of biological activities in adipose derived stem cells by histone deacetylation
Published 2025-01-01“…Pathway enrichment analysis showed cell cycle, ATP-dependent chromatin remodeling and DNA processes were among the affected pathways. …”
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