Epicardial Fat Tissue: A Potential Marker for Coronary Microvascular Dysfunction by Waiel Abusnina, Ilan Merdler, Matteo Cellamare, Kalyan R. Chitturi, Abhishek Chaturvedi, Irwin M. Feuerstein, Cheng Zhang, Sevket Tolga Ozturk, Teshome Deksissa, Vaishnavi Sawant, Kassandra Lopez, Lior Lupu, Dan Haberman, Itsik Ben‐Dor, Lowell F. Satler, Ron Waksman, Hayder D. Hashim, Brian C. Case

“…Logistic regression analysis was used to investigate the association between EFV and EFV index to CMD. Our study included 130 CMDR patients with associated chest CT; 35 were diagnosed with CMD. …”
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Higher Serum Uric Acid Is Associated with Higher Bone Mineral Density in Chinese Men with Type 2 Diabetes Mellitus by Dian-dian Zhao, Pei-lin Jiao, Jing-jia Yu, Xiao-jing Wang, Lin Zhao, Yan Xuan, Li-hao Sun, Bei Tao, Wei-qing Wang, Guang Ning, Jian-min Liu, Hong-yan Zhao

“…Therefore, we investigated the relationship between the serum UA and BMD in Chinese men with T2DM. In this cross-sectional study of 621 men with T2DM, BMDs at lumbar spine (L2–4), femoral neck (FN), and total hip (TH) were measured by dual-energy X-ray absorptiometry (DXA). …”
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Meteorin-like alleviates hepatic steatosis by regulating hepatic triglyceride secretion and fatty acid oxidation by Lingyu Song, Yali Huang, Lu Liu, Xuebing Chang, Laying Hu, Guifang Wang, Lifen Xu, Tian Zhang, Yuanyuan Wang, Ying Xiao, Hong Yang, Suye Ran, Qing Shi, Tuanlao Wang, Mingjun Shi, Yuxia Zhou, Bing Guo

“…Combining CDP-choline and an AMPK activator was sufficient to rescue hepatic steatosis in LKO-Met mice. …”
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Metformin Ameliorates D-Galactose-Induced Senescent Human Bone Marrow-Derived Mesenchymal Stem Cells by Enhancing Autophagy by Pingting Ye, Lei Feng, Dan Zhang, Ruihao Li, Yixuan Wen, Xiaohan Tong, Shuo Shi, Chunyan Dong

“…Furthermore, the results show that activation of 5′AMP-activated protein kinase (AMPK) by metformin enhances cell autophagy in senescent hBMSCs. …”
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A Molecular and Whole Body Insight of the Mechanisms Surrounding Glucose Disposal and Insulin Resistance with Hypoxic Treatment in Skeletal Muscle by R. W. A. Mackenzie, P. Watt

“…Yet hypoxia is also known to encourage glucose transport using insulin-dependent mechanisms, largely reliant on the metabolic master switch, 5′ AMP-activated protein kinase (AMPK). In addition, hypoxic exposure has been shown to improve glucose control in type 2 diabetics. …”
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Effects of Cow Dung Ash on Chemical and Geotechnical Properties of Lateritic Soil for Road Construction collected Shao-Malete Road in Kwara State, Nigeria by A. G. Adelodun, O. O. Amu, K. J. Ayinde

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A Quantum Perceptron: A New Approach for Predicting Rice Prices at the Indonesian Wholesale Trade Level by Solikhun, Tri Yunita

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Trifolirhizin: A Phytochemical with Multiple Pharmacological Properties by Varun Jaiswal, Hae-Jeung Lee

“…Mechanistic studies of trifolirhizin showed that it could act on important target genes and pathways such as the NF-κB-MAPK, EGFR-MAPK, AMPK/mTOR, and PI3K/Akt signaling pathways. These pathways are also implicated in various other diseases, suggesting the potential of trifolirhizin in therapeutic applications. …”
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Effectiveness of eHealth literacy interventions: a systematic review and meta-analysis of experimental studies by Chiara Barbati, Elvira Maranesi, Cinzia Giammarchi, Matteo Lenge, Manila Bonciani, Elisa Barbi, Giacomo Pietro Vigezzi, Mauro Dragoni, Tania Bailoni, Anna Odone, Roberta Bevilacqua

“…Subgroup analyses by intervention type, stratified by Collaborative Learning (CL) or Individualistic Learning (IL) showed significant increases in eHealth Literacy in the pre-post intervention analysis (CL: UMD = 5.19, CI = 0.01–10.38, N = 402; IL: UMD = 6.05; CI = 3.14–8.97, N = 623) and in the intervention vs. control analysis in the IL group (DMD = 4.98; CI = 1.77–8.12, N = 540). …”
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Systemic delivery of AAV5, AAV8, and AAV9 packaging a C5-12-microdystrophin-FLAG expression cassette in non-human primates by Mengping Liu, Erica Cook, Yanshan Dai, Erich Ehlert, Francois du Plessis, Jacek Lubelski, Bogdan G. Sleczka, Petia Shipkova, Zhuyin Li, Joshua Gamse, David Gordon, Leonard P. Adam, Paul C. Levesque, Glen B. Banks

“…Thus, a systemic dose of ∼1.18 × 1014 vector genomes/kg AAV8 is predicted to be safe and efficacious for treating Duchenne muscular dystrophy (DMD) but has significant room for improvement.…”
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Retraksi: Penerapan Data Mining Menggunakan Algoritma Apriori untuk Menentukan Pola Penyebab Gelandangan dan Pengemis by Wirta Agustin, Yulya Muharmi

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Reversal of neuronal tau pathology via adiponectin receptor activation by Eric R. McGregor, Danny J. Lasky, Olivia J. Rippentrop, Josef P. Clark, Samantha Wright, Mathew V. Jones, Rozalyn M. Anderson

“…AR reduced levels of phospho-tau and lowered NFT burden by a mechanism involving the energy-sensing kinase AMPK and the growth-sensing kinase GSK3b. The transcriptional response to AR included broad metabolic and functional pathways. …”
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Advances in Focal Segmental Glomerulosclerosis Treatment From the Perspective of the Newest Mechanisms of Podocyte Injury by Zhu Y, Xu G

“…Corresponding targeted medications such as Abatacept, chemokine receptor (CCR) inhibitors, CDDO-Im (2-Cyano-3,12-dioxooleana-1,9-dien-28-imidazolide), adenosine monophosphate-activated protein kinase (AMPK) activators, and Adalimumab are currently under investigation. …”
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Manhattan Distance-based K-Medoids Clustering Improvement for Diagnosing Diabetic Disease by Solikhun, Muhammad Rahmansyah Siregar, Lise Pujiastuti, Mochamad Wahyudi

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Unveiling FOXO3's metabolic contribution to menopause and Alzheimer's disease by Christopher O'Mahony, Oscar Hidalgo-Lanussa, George E. Barreto

“…We propose that FOXO3 plays a key role in the intersection of menopause and AD, given its dysregulation in both AD patients and postmenopausal women, modulating cellular metabolism through interactions with the AMPK/AKT/PI3K pathways. This relationship highlights the intersection between hormonal changes and increased AD susceptibility. …”
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Balancing Long Lifetime and Satisfying Fairness in WBAN Using a Constrained Markov Decision Process by Yingqi Yin, Fengye Hu, Ling Cen, Yu Du, Lu Wang

“…We formulate the problem of dynamically choosing which sensor should communicate with the AP to maximize network lifetime under the constraint of fairness as a constrained markov decision process (CMDP). The optimal lifetime and optimal policy are obtained by Bellman equation in dynamic programming. …”
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Bisphenol S exposure interrupted human embryonic stem cell derived cardiomyocytes differentiation through ER-NF-κB/ERK signaling pathway by Yongru Zhou, Lin Tian, Liang Wang, Wenjing Wu, Baofang Liang, Wei Xiong, Lishi Zhang, Xiaomeng Li, Jinyao Chen

“…The benchmark dose lower confidence limit (BMDL) of the relative expression of cTnT mRNA exposed by BPS during DP3 was the lowest among all the BMDLs of a good fit, with BMDL5 of 1.96 × 10−2 µg/mL, which is lower than the current reported exposure levels of BPS in maternal serum (0.03–0.07 ng/mL) and maternal umbilical cord serum (0.03–0.12 ng/mL).…”
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Dietary intake and risk assessment of nitrosamine in processed meat products among medical staff during their night shift by Dalia Ibrahim Tayel, Noorhan K. Farrag, Samar Mohamed Aborhyem

“…The Margin of Exposure (MOE) was calculated to assess risk, with a Benchmark Dose Lower Confidence Limit (BMDL)10 value of 29 µg/kg BW/day as the reference point. …”
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The Effect of Sleep Disruption on Cardiometabolic Health by SeokHyun Hong, Da-Been Lee, Dae-Wui Yoon, Seung-Lim Yoo, Jinkwan Kim

“…Sleep loss affects key metabolic regulators, including AMPK signaling and disrupts the secretion of metabolic hormones such as leptin and ghrelin. …”
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An optimized ensemble grey wolf-based pipeline for monkeypox diagnosis by Ahmed I. Saleh, Asmaa H. Rabie, Shimaa E. ElSayyad, Ali E. Takieldeen, Fahmi Khalifa

“…Statistical analysis also confirmed that the proposed AMDS outperformed other models after running 50 times. …”
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