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Macrophage Plasticity and the Role of Inflammation in Skeletal Muscle Repair
Published 2013-01-01“…If damage persists, as in skeletal muscle pathologies such as Duchenne muscular dystrophy (DMD), macrophage infiltration perpetuates and leads to progressive fibrosis, thus exacerbating disease severity. …”
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2163
Single-Pixel Compressive Digital Holographic Encryption System Based on Circular Harmonic Key and Parallel Phase Shifting Digital Holography
Published 2022-01-01“…The digital mirror device (DMD) is placed between the object and a single-pixel detector for acquiring fewer hologram measurements. …”
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2164
The effect of vermicompost leachate and split root system of tomato on the growth and crop per drop
Published 2024-03-01Get full text
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2165
Development of proactive mode of providing tax deductions for personal income tax
Published 2024-05-01“…The authors analysed the practice of application of the simplified procedure for obtaining property and investment tax deductions; statistical data of the Federal Tax Service of Russia on the provision of tax deductions in a simplified manner (1-DDK statistical form “On the declaration of personal income”). …”
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2166
PGC-1α Promotes mitochondrial biosynthesis and energy metabolism of goose fatty liver
Published 2025-01-01“…However, the mRNA expression levels of PGC-1β, SIRT5 and AMPKα were decreased after PGC-1α interference. Furthermore, we observed a significant increase in the mitochondrial DNA (mtDNA) copy number, the activity of mitochondrial respiratory chain complex Ⅳ (MRCC Ⅳ), succinate dehydrogenase (SDH), malate dehydrogenase (MDH), and the NAD+/NADH ratio in fatty liver. …”
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2167
Stimulation of Alpha1-Adrenergic Receptor Ameliorates Cellular Functions of Multiorgans beyond Vasomotion through PPARδ
Published 2020-01-01“…Widely distributed α1-adrenergic receptors (ARs) are physiologically stimulated during exercise, were reported to associate with the activating energetic AMPK pathway, and are expected to have biological effects beyond their hemodynamic effects. …”
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2168
Dipeptidyl-Peptidase 4 Inhibitor Sitagliptin Ameliorates Hepatic Insulin Resistance by Modulating Inflammation and Autophagy in ob/ob Mice
Published 2018-01-01“…Moreover, sitagliptin increased the levels of phosphorylation of AMPK and decreased those of mTOR. This study indicates that sitagliptin significantly ameliorates the development of hepatic steatosis and insulin resistance in ob/ob mice by inhibiting inflammatory responses and activating autophagy via AMPK/mTOR signaling pathway.…”
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2169
Drug Repositioning for Gynecologic Tumors: A New Therapeutic Strategy for Cancer
Published 2015-01-01“…Metformin, an antidiabetic drug, is effective for endometrial cancer through inhibition of the PI3K-Akt-mTOR pathway by activating LKB1-AMPK and reduction of insulin and insulin-like growth factor-1 due to AMPK activation. …”
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2170
Predictor’s of Mortality in Patients with Aneurysmal Subarachnoid Haemorrhage and Reebleding
Published 2015-01-01“…“Ameijeiras Brother’s” and “Cmdt. Manuel Fajardo” Hospitals enrolled 64 patients (multicentre retrospective cohort) with aneurysmal subarachnoid haemorrhage and rebleeding. …”
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2171
Impact of frequent ARID1A mutations on protein stability provides insights into cancer pathogenesis
Published 2025-01-01“…By combining computational stability from web server tools, the structural dynamics from replica exchange discrete molecular simulation (rexDMD), and thermal and chemical denaturation experiments, we found that the R1020S mutation severely decreases structural stability, making it the most impactful, while M1022K has minimal effect, and others lie in between. …”
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2172
Unsteady Flow Mechanisms of the Stability Improvement for an Optimized Compressor
Published 2025-02-01“…Then, the unsteady mechanisms of the flow stability enhancement for the optimized compressor are analyzed by the dynamic-mode-decomposition (DMD) method. It is found that the decrease of the energy proportion of the inherent mode and the increase of the low-frequency multi-scale modes are correlated to the flow instability of the compressor. …”
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2173
Wharton’s Jelly-Derived Mesenchymal Stem Cells with High Aurora Kinase A Expression Show Improved Proliferation, Migration, and Therapeutic Potential
Published 2022-01-01“…Moreover, AURKA from human WJ-MSCs regulated the antiapoptotic effect of skeletal muscle cells by upregulating the chemokine (C motif) ligand (XCL1); this was further confirmed in the mdx mouse model. Taken together, the results indicated that AURKA and DOCK2 can be used as potential biomarkers for proliferation and migration of human WJ-MSCs. …”
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2174
IMAGE PROCESSING AT ELLIPSOIDAL PHOTOMETRY
Published 2016-06-01“…As a CCD detector was used monochrome camera DMK-21Au04.AS, and ellipsoidal reflector with an eccentricity of 0.66 and working aperture of 33.75 mm. …”
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Diurnal changes of corneal epithelial and stromal thickness maps and visual quality in mild form of Fuchs’ endothelial corneal dystrophy
Published 2025-01-01“…Testing included measurement of uncorrected distance visual acuity (UDVA), best corrected twilight vision (TV), and contrast sensitivity function (CSF) testing (Vista Vision Far-Pola, DMD MedTech charts). Corneal epithelial and stromal parameters were evaluated with anterior segment optical coherence tomography (AngioVue, AvantiRTVue-XR; Optovue, CA, USA). …”
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2176
“The Body Hair that Grows on the Head”
Published 2018-11-01“…In this chapter, we introduce readers to the Amdo Tibetan comedian, poet and performance artist Menla-kyap [sMan bla skyabs] through a translation of his 2009 autobiographical narrative, “Views on Hair and Hairstyles.” …”
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Energy metabolism and the intestinal barrier: implications for understanding and managing intestinal diseases
Published 2025-01-01“…Pharmacological strategies to elevate SCFA levels can activate the AMPK pathway and rectify abnormalities in energy metabolism. …”
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2178
Fimasartan Ameliorates Nonalcoholic Fatty Liver Disease through PPARδ Regulation in Hyperlipidemic and Hypertensive Conditions
Published 2017-01-01“…Consequently, fimasartan ameliorates nonalcoholic fatty liver disease mainly through the activation of oxidative metabolism represented by PPARδ-AMPK-PGC-1α pathway.…”
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ALDOA contributes to colorectal tumorigenesis and metastasis by targeting YAP
Published 2025-01-01“…Herein, ALDOA was identified to be a new metabolic regulator of YAP that suppresses the activation of AMPK signaling. This could suggest a novel avenue for treating CRC by inhibiting both ALDOA and YAP signaling.…”
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Protective Effect of Thalidomide on 2,4,6-Trinitrobenzenesulfonic Acid-Induced Experimental Colitis in Rats via the Inhibition of T Helper 17 Cells
Published 2020-01-01“…After 7 days, the disease activity index (DAI), colon macroscopic damage index (CMDI), and tissue damage index (TDI) were evaluated. …”
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