Healthcare utilisation and expenditure patterns for cardio-metabolic diseases in South Asian cities: the CARRS Study by Dorairaj Prabhakaran, Kavita Singh, Roopa Shivashankar, Nikhil Tandon, Mohammed K Ali, Kalpana Singh, V Mohan, Priti Gupta, Ajay Vamadevan, Muhammad Masood Kadir, K M Narayan

“…We also calculated distress financing (DF) as having to borrow or sell assets to pay for CMD treatment and identified sociodemographic groups at most risk of DF using multiple regression.Results Of 16 287 CARRS participants, 2883 (17.7%) reported receiving treatment for CMDs. …”
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Microfluidic-Based F-Labeling of Biomolecules for Immuno–Positron Emission Tomography by Kan Liu, Eric J. Lepin, Ming-Wei Wang, Feng Guo, Wei-Yu Lin, Yi-Chun Chen, Shannon J. Sirk, Sebastian Olma, Michael E. Phelps, Xing-Zhong Zhao, Hsian-Rong Tseng, R. Michael van Dam, Anna M. Wu, Clifton K.-F. Shen

“…We describe an improved method using a digital microfluidic droplet generation (DMDG) chip, which provides computer-controlled metering and mixing of 18 F tag, biomolecule, and buffer in defined ratios, allowing rapid scouting of reaction conditions in nanoliter volumes. …”
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Visualization of Online-Game Players Based on Their Action Behaviors by Ruck Thawonmas, Keita Iizuka

“…The proposed approach consists of two visualization techniques: classical multidimensional scaling (CMDS) and KeyGraph. CMDS is for discovering clusters of players who behave similarly. …”
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Laws of Gas Diffusion in Coal Particles: A Study Based on Experiment and Numerical Simulation by Yongjiang Hao, Xiaofeng Ji, Jiewen Pang

“…The cumulative methane desorption quantity (CMDQ) with time increasing was obtained to show that the reciprocal of CMDQ was in linear relation with the reciprocal of the square root of time, and the correlation coefficients were all above 0.99, on basis of which an empirical formula of CMDQ was established. …”
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Constitutive Androstane Receptor-Mediated Inhibition of Metformin on Phase II Metabolic Enzyme SULT2A1 by Xiaowen Hu, Mengsiyu Li, Chunxue Zhang, Shuguang Pang

“…HepaRG was used to evaluate the protein expression of pregnane X receptor (PXR), the constitutive androstane receptor (CAR), SULT2A1, AMP-activated protein kinase (AMPK), and phosphorylation of AMPK (p-AMPK), respectively, at different concentrations of metformin with or without rifampin (human PXR activator) and CITCO (human CAR activator). …”
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Label-free proteomic analysis of Duchenne and Becker muscular dystrophy showed decreased sarcomere proteins and increased ubiquitination-related proteins by Juliana Cristina Tobar da Silva, Mariângela Rangel Alves Nogueira, Yara Martins da Silva, Fábio César Sousa Nogueira, Nathalie Henriques Silva Canedo, Katia Carneiro, Denise de Abreu Pereira

“…These conditions often result from structural defects in the Dystrophin–Glycoprotein Complex (DGC), as seen in Duchenne Muscular Dystrophy (DMD) and Becker Muscular Dystrophy (BMD). Since MDs currently have no cure, research has focused on identifying potential therapeutic targets to improve patients’ quality of life. …”
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Neuroprotective Role of Transchalcone in Parkinson‘s Disease through AMP-activated Protein Kinase-mediated Signaling Pathway by Yao Cheng, Shaik Althaf Hussain, Turki Mayudh Alrubie, Xiaomin Zhang

“…The expression of phosphorylated AMPK, PGC-1α, and SIRT1 was analyzed by Western blotting. …”
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Boosting Cyberattack Detection Using Binary Metaheuristics With Deep Learning on Cyber-Physical System Environment by Alanoud Al Mazroa, Fahad R. Albogamy, Mohamad Khairi Ishak, Samih M. Mostafa

“…The ACAD-BMDL method uses Z-score normalization to scale the input dataset. …”
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AICAR Protects against High Palmitate/High Insulin-Induced Intramyocellular Lipid Accumulation and Insulin Resistance in HL-1 Cardiac Cells by Inducing PPAR-Target Gene Expression by Ricardo Rodríguez-Calvo, Manuel Vázquez-Carrera, Luis Masana, Dietbert Neumann

“…AMPK activation by AICAR was confirmed by increased phospho-Thr172-AMPK and phospho-Ser79-ACC protein levels in HL-1 cardiomyocytes. …”
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Metabolic Basis for Thyroid Hormone Liver Preconditioning: Upregulation of AMP-Activated Protein Kinase Signaling by Luis A. Videla, Virginia Fernández, Pamela Cornejo, Romina Vargas

“…Reactive oxygen species (ROS) lead to cellular AMPK activation and downstream signaling under several experimental conditions. …”
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District-level differences in the distribution of mental and substance use disorders in Assam by Vijay Gogoi, Priyadarshee Abhishek, Soumik Sengupta, Indrajeet Banerjee, Samir Sarma, H. Sobhana, Sonia P. Deuri, Kangkan Pathak, Gautham M. Sukumar, Vivek Benegal, Girish N. Rao, Mathew Varghese, Gopalkrishna Gururaj

“…Aims: To assess interdistrict differentials in common mental disorders (CMDs), severe mental disorders (SMDs), socioeconomic impact, healthcare utilization, and mental disability across three districts sampled in NMHS in Assam. …”
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The role of adenosine monophosphate-activated protein kinase and serum amyloid A proteins in the early diagnosis of neonatal sepsis by P.A. Orujova, N.H. Sultanova

“…Blood samples were analyzed for CRP, PCT, AMPK, and SAA levels using enzyme-linked immunosorbent assay (ELISA) kits. …”
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Amelioration of Oxidative Stress in Rats with Chronic Obstructive Pulmonary Disease through Shenqi Huatan Decoction Activation of Peroxisome Proliferator-Activated Receptor Gamma-M... by Jingjing Chen, Wenxiao Qiao, Xiaoming Xue, Dian Li, Ye Zhang, Di Xie, Jinyun Wang, Yaoqin Sun, Shuo Yang, Zhuomin Yang

“…In the lung tissue of rats with COPD, large doses of SQHT intervention dramatically increased AMPK protein expression, AMPK-α, FOXO3a, MnSOD, and PPARγ, indicating that SQHT may reduce oxidative stress by activating the PPARγ-mediated AMPK/FOXO3a signaling pathway. …”
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NFP:enabling network function parallelism in NFV by Jun BI, Chen SUN, Heng YU

“…Software-based sequential service chains in network function virtualization (NFV) could introduce significant performance overhead.Current acceleration efforts for NFV mainly target on optimizing each component of the sequential service chain.However,based on the statistics from real world enterprise networks,it was observed that 53.8% network function (NF) pairs could work in parallel.In particular,41.5% NF pairs could be parallelized without causing extra resource overhead.NFP was presented,a high performance framework,that innovatively enabled network function parallelism to improve NFV performance.NFP consisted of three logical components.Firstly,NFP provided a policy specification scheme for operators to intuitively describe sequential or parallel NF chaining intents.Secondly,NFP orchestrator intelligently identified NF dependency and automatically compiled the policies into high performance service graphs.Thirdly,NFP infrastructure performed light-weight packet copying,distributed parallel packet delivery,and load-balanced merging of packet copies to support NF parallelism.An NFP prototype based on DPDK in Linux containers was implemented.The evaluation results show that NFP achieves significant latency reduction for real world service chains.…”
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The Combined Application of Surface Floating Wetlands and Bottom Anaerobic to Remediate AMD-Contaminated Lakes by Tianling Fu, Yonggui Wu, Hu Wang, Kaiju Chen, Yan Zeng, Zhongzheng Wen, Zhengyan Ran, Li He

“…The eco-remediation system (RW) which combined surface floating wetlands and bottom anaerobic sediments (SFW-BAS) was selected for AMD-contaminated lakes (AMDW). Meanwhile, AMDW and nature aquatic ecosystems (NW) were set as the control groups, respectively. …”
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Metformin Regulating miR-34a Pathway to Inhibit Egr1 in Rat Mesangial Cells Cultured with High Glucose by Can Wu, Ningning Qin, Huiwen Ren, Min Yang, Shuang Liu, Qiuyue Wang

“…Background. Activating AMPKα negatively regulates Egr1 to inhibit inflammatory cytokines in high glucose. miR-34a inhibition increases phosphorylated AMPKα through mediating SIRT1 to suppress the development of fatty liver. …”
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Neuroprotective Effects of Metformin and Berberine in Lipopolysaccharide-Induced Sickness-Like Behaviour in Mice by Triveni Kodi, Sharanya Praveen, Sravan Kumar Paka, Runali Sankhe, Adarsh Gopinathan, Nandakumar Krishnadas, Anoop Kishore

“…Metformin, an antidiabetic agent acting via AMPK activation, possesses anti-inflammatory properties. …”
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Effect of variation in gridded cattle diet composition on estimated enteric methane emissions in data sparse tropical regions by J.Y. Mutua, A.J. Duncan, T.P. Robinson, S. Fraval, A.M.O. Notenbaert, G.R. Watmough

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The Impact of Big Math for Little Kids on Children’s Number Skills by Ayşe Kılıçkaya, Canan Avcı

“…Findings indicated that children who were exposed to the global MoNE curriculum supplemented with the BMLK had greater gains than did those who experienced only the MoNE curriculum. …”
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Berberine-induced browning and energy metabolism: mechanisms and implications by Aslıhan Alpaslan Ağaçdiken, Zeynep Göktaş

“…While investigating the mechanism of action of berberine, both the AMPK pathway is being examined in more detail and alternative pathways are being explored. …”
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