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15021
Autoimmune Hepatitis in Children: The Current State of the Problem
Published 2018-11-01“…For a small number of patients, who do not respond to standard treatment and those who suffer from frequent disease relapses, it is advisable to offer an alternative immunosuppressive treatment, the effectiveness of which is still ambiguous and poorly understood (including, in order of priority, mycophenolate mofetil, calcineurin inhibitors, rituximab, Inhibitor of tumor necrosis factor-alpha). …”
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15022
The spiritual way to desistance?
Published 2024-11-01“…Prior to matching, former inmates who participated in the religious activities were considerably less likely to be reconvicted within three years of release (37 percent) compared to those who did not participate (59 percent). …”
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15023
Cost-effectiveness analysis of proactive home visits compared with site-based community health worker care on antenatal care outcomes in Mali: a cluster-randomised trial
Published 2024-12-01“…Introduction Despite recommendations from the WHO, antenatal care (ANC) coverage remains low in many low-income and middle-income countries (LMICs). …”
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15024
A Risk Management Approach to Global Pandemics of Infectious Disease and Anti-Microbial Resistance
Published 2024-11-01“…These distinct motivations necessitate tailored responses, yet the WHO aggregates these attacks in a manner that hampers effective intervention. …”
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15025
The relationship between work-life balance and psychological well-being: an empirical study of metro rail travelers working in the information technology sector
Published 2025-01-01“…The study also investigated the impact of occupational stress and work–life balance on the psychological well-being of metro travelers who work in the information technology sector, modeling lower- and higher-order constructs.MethodsA quantitative survey method was used, and the data were gathered from information technology employees who frequently travel on Metro Rail to commute to the office and return home when the COVID-19 pandemic peaked in India in 2022. …”
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15026
Phase I study of efineptakin alfa (NT-I7) for the treatment of Kaposi sarcoma
Published 2025-02-01“…Absolute lymphocyte counts, CD4+ and CD8+ T-cell counts increased among all participants following administration of NT-I7. Participants who experienced a response had HIV and lower CD4/CD8 ratio at baseline and throughout the study as compared with those who did not have KS response to NT-I7.Conclusions Preliminary data demonstrate safety and activity of IL-7 in patients with KS and activity specifically among individuals HIV-associated KS.Trial registration number NCT04893018.…”
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15027
Representativeness of the dabigatran, apixaban and rivaroxaban clinical trial populations to real-world atrial fibrillation patients in the United Kingdom: a cross-sectional analys...
Published 2012-12-01“…This study aimed to assess the representativeness for the real-world AF population, particularly the population eligible for anticoagulants.Design A cross-sectional database analysis.Setting Dataset derived from the General Practice Research Database (GPRD).Primary and secondary outcomes measure The proportion of real-world patients with AF who met the inclusion/exclusion criteria for RE-LY, ARISTOTLE and ROCKET-AF were compared. …”
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15028
Exploring the clinical profiles and management of juvenile dermatomyositis in Africa: a survey of African rheumatology care providers
Published 2025-01-01“…Results Forty-three (12%) of the 363 providers who received the survey started it. Among the 43 who started the survey, 37 (86%) provided consent and manage JDM patients; of these 37 providers, 4 (11%) partially and 16 (43%) fully completed the survey. …”
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15029
The effect of thermoelectric craniocerebral cooling device on protecting brain functions in post-cardiac arrest syndrome
Published 2025-01-01“…AimThis study aimed to protect brain functions in patients who experienced in-hospital cardiac arrest through the application of local cerebral hypothermia. …”
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15030
Sex disparity in the association between alcohol consumption and sarcopenia: a population-based study
Published 2025-02-01“…Compared to nondrinkers, an increased risk of developing sarcopenia was observed in participants who consumed alcohol 2 days (OR: 2.36; 95% CI: 1.40–3.99) or > 2 days (OR: 1.84; 95% CI: 1.10–3.07) per week, and those who engaged in binge drinking for ≤1 day per month (OR: 1.68; 95% CI: 1.09–2.60) or > 1 day per month (OR: 2.10; 95% CI: 1.10–4.01). …”
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15031
The impact of anticoagulant-related bleeding on quality of life: Development of a novel measure based on perspectives from older adults.
Published 2025-01-01“…<h4>Background</h4>Venous thromboembolism (VTE) and atrial fibrillation (AF) disproportionately affect older adults, who are at increased risk of bleeding from treatment with anticoagulant therapy. …”
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15032
Effect of Mind Sound Resonance Technique on Pulmonary Function and Smoking Behavior among Smokers – A Prospective Randomized Control Trial
Published 2024-12-01“…Methodology: A total of 197 subjects were screened among whom 80 were recruited and randomly allocated (1:1) to a study group (SG) (n = 40) who received 10 days of 25-min MSRT intervention and a control group (CG) (n = 40) who received health education during the same period. …”
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15033
The effectiveness of providing training and ongoing support to foster cultural humility in volunteers serving as mentors to youth of color: a mixed-methods study protocol
Published 2025-01-01“…Abstract Background The aim of this randomized control trial is to test the impact of providing additional training and support to volunteers who are paired with youth of color in the Big Brothers Big Sisters (BBBS) community-based mentoring program. …”
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15034
A comparison of drug‐eluting stent and coronary artery bypass grafting in mildly to moderately ischemic heart failure
Published 2022-06-01“…Methods and results From January 2016 to December 2017, we enrolled patients with mildly to moderately reduced EF (35–50%) who had undergone PCI with DESs or CABG. Patients with a history of CABG, presented with acute ST‐elevation myocardial infarction (MI) or acute heart failure, and patients who had undergone CABG concomitant valvular or aortic surgery were excluded. …”
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15035
Preferences for and acceptability of long-acting HIV prevention products among pregnant and lactating women accessing health services in Kenya: a mixed method cross-sectional analy...
Published 2025-01-01“…The most preferred PrEP formulations were injectable (251/434, 57%) and implantable (175/434, 40%) options. Participants who preferred injectable PrEP had 8.56 times higher odds of considering ease of use as a reason. …”
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15036
Using the diffusion of innovations theory to understand factors associated with COVID-19 vaccination among tobacco users.
Published 2024-01-01“…A population of concern are high-risk individuals such as adults who are tobacco users, since COVID-19 is a respiratory disease that affects the lungs. …”
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15037
Factors associated with non-response and nutritional status of non-responders at 6-month post-discharge: a cohort study nested in a MUAC-based nutrition programme for acutely malno...
Published 2024-08-01“…Logistic regression was used to analyze factors associated with non-responders compared with children who recovered.ResultsOf the 1,112 children enrolled, 909 recovered and 139 were non-responders, of which 127 (80.6%) had significant MUAC gain (mean: +9.6 mm, sd = 5.1) at discharge. …”
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15038
Uptake and 4-week outcomes of an ‘opt-out’ smoking cessation referral strategy in a London-based lung cancer screening setting
Published 2025-02-01“…Here, we report uptake and short-term outcomes of an ‘opt-out’ smoking cessation referral strategy in an LCS cohort.Methods Individuals currently smoking tobacco who attended a face-to-face lung health check in the SUMMIT study (NCT03934866) were offered very brief advice on smoking cessation and where possible, an ‘opt-out’ referral to their local stop smoking service (SSS). …”
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15039
Practical application of a nutraceutical in age-related macular degeneration
Published 2018-07-01“…Group 1 — 20 patients (34 eyes) who received Retinorm 1 capsule 3 per day during meals, group 2 — 20 patients (32 eyes) who received standard conservative therapy for 16 weeks. …”
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15040
Evaluation of Sialic Acid Levels in the Umbilical Cord Blood of Newborns of Diabetic and Non-Diabetic Mothers and the Relation with Poor Neonatal Outcome
Published 2021-04-01“…The others, in decreasing order, were participants with Type II diabetes (33.00±4.1) and gestational diabetes (20.87±3.7) and the difference was statistically significant (p=0.001). Those who were diabetic and on insulin treatment had significantly higher sialic acid values than those who were on diabetic diet only (p=0.007). …”
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