The impact of margins and re‐resection in pediatric synovial sarcoma by Andres F. Espinoza, Priya B. Shetty, Jillian C. Jacobson, Hannah Todd, Kelley Harrell, Alfred F. Trappey, John Doski, Eumenia C. Castro, Nicole I. Montgomery, M. Fatih Okcu, Rajkumar Venkatramani, Dai H. Chung, Sanjeev A. Vasudevan

“…Patients with R1 on initial or re‐resection had significantly worse OS than patients who had R0 resection on initial or re‐resection (HR = 10.12, p = 0.005). …”
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Efficacy of ceftazidime-avibactam with or without polymyxin for carbapenem-resistant Klebsiella pneumoniae infections after initial treatment with polymyxin by Jingli Lu, Yani Ma, Zhe Cao, Baoling Zhu, Luna Fan, Haiyang Meng

“…We retrospectively reviewed cases of infections caused by CRKP in adults who received CAZ-AVI as salvage therapy. Clinical features and outcomes were described, and a logistic regression model was used to assess the risk factors associated with in-hospital crude mortality. …”
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Clinical Analysis of the Patients with Isolated Low-Velocity Penetrating Neck Injury by Junepill Seok, Hyun Min Cho

“…The patients who had deep injuries showed significant difference against the patient with superficial injury (98.0 vs. 129.1, p=0.008). …”
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Next-Generation Sequencing Analysis on Image-Guided Biopsy Samples in Early-Stage Lung Cancer: Feasibility Study and Comparison With Surgical Samples by Louis Gros, MD, Rowena Yip, PhD, MPH, Arel Golombeck, MD, David F. Yankelevitz, MD, Claudia I. Henschke, PhD, MD

“…Results: Among the 654 participants with lung tumors of 30 mm or less who underwent surgery, 70 had NGS on prior biopsies. …”
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Can primary care research be conducted more efficiently using routinely reported practice-level data: a cluster randomised controlled trial conducted in England? by Jeremy Horwood, Alastair D Hay, Patricia Jane Lucas, Clare Clement, Peter S Blair, Jodi Taylor, Christie Cabral, Martin C Gulliford, Jenny Ingram, Padraig Dixon, Nick Francis, Athene Lane, Grace Young, Elizabeth Beech, Penny Seume, Scott Bevan, Sam T Creavin

“…By using aggregate level, routinely collected data for the coprimary outcomes, we removed the need to recruit individual participants.Setting Primary care.Participants Baseline data from general practitioner practices and interviews with individuals from Clinical Research Networks (CRNs) in England who helped recruit practices and Clinical Commission Groups (CCGs) who collected outcome data.Intervention The intervention included: (1) explicit elicitation of parental concerns, (2) a prognostic algorithm to identify children at low risk of hospitalisation and (3) provision of a printout for carers including safety-netting advice.Coprimary outcomes For 0–9 years old—(1) Dispensing data for amoxicillin and macrolide antibiotics and (2) hospital admission rate for RTI.Results We recruited 294 of the intended 310 practices (95%) representing 336 496 registered 0–9 years old (5% of all 0–9 years old children). …”
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The role of diet therapy in insulin resistance in women with polycystic ovary syndrome by H.B. Semenyna, T.V. Fartushok, N.V. Fartushok, N.Ya. Dumanchuk, O.M. Yurchyshyn

“…The study did not include pregnant, lactating women who took hormonal therapy and/or insulin sensitizers during the last 2 months, had liver, kidney, and heart diseases that failed local treatment of hirsutism, with congenital hyperplasia of the adrenal glands, androgen-secreting tumors, Cushing's syndrome. …”
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Efficacy and safety of hemoporfin photodynamic therapy in treating port-wine stains in Chinese children: a systematic review and meta-analysis by Jing Xu, Hongxin Li

“…Regardless of whether the outcome variable was efficacy I or efficacy II, the therapeutic efficacy in children with PWS aged 0–3 years was superior to those aged 3–6 and 6–18 years, and children who underwent a treatment course of ≥3 sessions showed better outcomes compared to those who have only 1 or 2 sessions. …”
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Comparison of the Efficacy and Safety of Two Cryotherapy Protocols in the Treatment of Common Viral Warts: A Prospective Observational Study by Jihan M. Muhaidat, Firas A. Al-qarqaz, Diala M. Alshiyab, Hadeel S. Alkofahi, Yousef Khader, Mawaddah Y. Ababneh

“…A prospective observational study was conducted; it involved 80 patients with common warts on the hands and feet who were treated with cryotherapy done by two dermatologists who use different protocols; group 1 (45 patients) were treated by a single cycle of 10 seconds of freezing at 2 weekly intervals, and group 2 (35 patients) received a single cycle of 20 seconds of freezing at 4-weeks intervals. …”
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Five lessons from a mid-level health manager intervention to increase uptake of tuberculosis prevention therapy in Uganda: ‘it is a completely different thing to implement what you... by Jason Johnson-Peretz, Canice Christian, Cecilia Akatukwasa, Fred Atwine, Elijah Kakande, Moses R. Kamya, Diane V. Havlir, Carol S. Camlin, Gabriel Chamie

“…Conclusion These practices reached beyond outcome measures to address root problems around the DHO’s range of authority and elicit buy-in from district health workers. …”
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HDL proteome and apolipoproteins concentrations in severe ICU COVID-19 patients by Floran Begue, Bryan Veeren, Philippe Rondeau, Aline-Marie Florence, Simon Jamard, Philippe Montravers, Sébastien Tanaka, Olivier Meilhac, on behalf of French COVID Study Group

“…The study aimed to assess apolipoprotein levels in COVID-19 patients who either survived or died following ICU admission. …”
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Fatal toxoplasmic encephalitis triggered by anti-TNF therapy by Rodrigo A. Montoro, Michael Moran, Katherine A. Overmyer, Andrew Periaccante, Joshua J. Coon, Swapnil Lanjewar, Laura J. Knoll, Rob Striker

“…Here we present a 74-year-old woman who developed fatal cerebral toxoplasmosis after anti-tumor necrosis factor-α (TNF-α). …”
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Interrelationship between altered metabolites and the gut microbiota in people living with HIV with different immune responses to antiretroviral therapy by Xuebin Tian, Zhongyao Gao, Yiwen Xie, Xiangyun Lu, Yulong Zhao, Peng Yao, Mingqing Dong, Lifeng Yu, Nanping Wu

“…Methods: We analyzed the gut microbiota composition, metabolites, and immune markers in 38 PLWH who showed an immunological response (IR) and 32 who did not (INR), as classified according to CD4+ T-cell levels after 24 months of ART. …”
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Prevalence of digestive diseases in patients with excessive body weight and obesity (<i>according to data of polyclinic department of versatile clinic</i>) by I. R. Popova

“…Retrospective study of diseases of digestive organs prevalence included 1504 patients, who have visited polyclinic department in 2010 : 659 with excessive body weight – body mass index (BMI) 25,0 to 29,9 kg/m2), 610 with obesity (BMI ≥30 кг/м2) and 235 with normal weight (BMI 18,5 to 24,9 kg/m2), the latter made control group. …”
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Relationship between maternal pre-pregnancy BMI and neonatal birth weight in pregnancies with gestational diabetes mellitus: a retrospective cohort study by Qiuping Liao, Qiuping Liao, Qiuping Liao, Tiantian Yu, Tiantian Yu, Tiantian Yu, Jiajia Chen, Jiajia Chen, Jiajia Chen, Xiuqiong Zheng, Xiuqiong Zheng, Xiuqiong Zheng, Lianghui Zheng, Lianghui Zheng, Lianghui Zheng, Jianying Yan, Jianying Yan, Jianying Yan

“…The percentage of LGA babies was higher in women who were overweight or obese compared to those of normal weight. …”
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The Old Woman’s Farcical Rejuvenation in The Rejuvenation of Miss Semaphore (1897) by Somi Ahn

“…My goal is therefore to discuss how Eccles uses humour in letting her protagonist accidentally live backward and develop into a social activist, who testifies in court as a victim and witness of child abuse in the workhouse. …”
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Non-linear dose-response relationship between uterine artery pulsatility index and risk of preeclampsia in early pregnancy: A secondary analysis based on a nested cohort study. by Shaou Wang, Hao Dong

“…<h4>Methods</h4>A total of 5000 pregnant women who underwent prenatal examination and delivery at the same hospital were included in this nested cohort study. …”
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Clinical Profile and Outcome of Esophageal Button Battery Ingestion in Children: An 8-Year Retrospective Case Series by Mustafa Erman Dörterler

“…A total of 17 children who presented after ingesting a button battery and were treated at a tertiary care clinic over an 8-year period were included in this retrospective case series study. …”
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Navigating DR-TB Treatment care: a qualitative exploration of barriers and facilitators to retention in care among people with history of early disengagement from drug-resistant tu... by Ndiviwe Mphothulo, Sindisiwe Hlangu, Jennifer Furin, Mosa Moshabela, Marian Loveday

“…As a consequence, advances in DR-TB diagnostics and treatment have not resulted in DR-TB programs meeting the 75% treatment success targets set by the World Health Organization (WHO). Methods We interviewed people with DR-TB who had disengaged from care and their family members to identify barriers and facilitators to retention in care as well as possible strategies to address these barriers. …”
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Real life experience of a screening strategy for latent tuberculosis before treatment with biologicals in indian patients with rheumatic diseases by Anand N Malaviya, Ravita Thakaran, Roopa Rawat, Sanjiv Kapoor, Shriram Garg, Sadhana S Baghel, Christy Messi, Vivekanand, Qamar Zaheer

“…The proportion of patients developing active TBI during the same period of follow-up did not differ between those who were and those who were not treated with bDMARDs. …”
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The Impact of Insulin Degludec on Glucocorticoid-Induced Hyperglycemia in Patients with Diabetes and COVID-19 Infection by Varun Prasanna, Ravindranath Venketesan

“…Conclusion: IDeg is an effective and safe insulin for managing hyperglycemia in PWD who developed SIH during hospitalization for moderate-to-severe COVID-19.…”
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