Examining the effect of direct-from-blood bacterial testing on antibiotic administration and clinical outcomes: a protocol and statistical analysis plan for a pragmatic randomised... by Li Wang, Wesley H Self, Todd W Rice, Matthew W Semler, Karen F Miller, Cheryl L Gatto, Andrea Fletcher, Romney M Humphries, Joanna L Stollings, Adrienne Baughman, Jakea Johnson, Edward T Qian, Mary Lynn Dear, David C Gaston, Ariel A Lewis, George E Nelson, Benjamin J Ereshefsky, Matthew A Christensen, Ritu Banerjee, Dan Albert, Alison Benton, Laura Bobbitt, Carleigh Burns, Timothy Duff, David C. Gaston, MLS Sharon Glover, Allyson Hobbie, Austin Ing, Gabriel Kemp, Sheryl Mangrum, Geoff Mavrak, Kelly Moser, David Mulherin, Shannon Pugh, Matthew Rodgers, Chrissie Schaeffer, Adam Turner, Sabrina Shipman, Halden Z VanCleave, Hamilton Wen Li Wang, LaKeysha Wiggins

“…The trial will enrol 500 adult patients presenting to the emergency department at Vanderbilt University Medical Center with suspected bacterial infection who have been initiated on empiric intravenous vancomycin. …”
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Obesity prevalence among healthcare professionals in England: a cross-sectional study using the Health Survey for England by Richard G Kyle, Jane Wills, Catherine Mahoney, Louise Hoyle, Muireann Kelly, Iain M Atherton

“…Objective To estimate obesity prevalence among healthcare professionals in England and compare prevalence with those working outside of the health services.Design Cross-sectional study based on data from 5 years (2008–2012) of the nationally representative Health Survey for England.Setting England.Participants 20 103 adults aged 17–65 years indicating they were economically active at the time of survey classified into four occupational groups: nurses (n=422), other healthcare professionals (n=412), unregistered care workers (n=736) and individuals employed in non-health-related occupations (n=18 533).Outcome measure Prevalence of obesity defined as body mass index ≥30.0 with 95% CIs and weighted to reflect the population.Results Obesity prevalence was high across all occupational groups including: among nurses (25.1%, 95% CI 20.9% to 29.4%); other healthcare professionals (14.4%, 95% CI 11.0% to 17.8%); non-health-related occupations (23.5%, 95% CI 22.9% to 24.1%); and unregistered care workers who had the highest prevalence of obesity (31.9%, 95% CI 28.4% to 35.3%). …”
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Evaluation of de novo donor specific antibodies after kidney transplantation in the era of donor-derived cell-free DNA by Yuan Tian, Lukas Frischknecht, Anna Mallone, Fabian Rössler, Thomas Schachtner, Jakob Nilsson

“…While de novo donor-specific antibodies (dnDSA) are crucial in ABMR, the relationship between dd-cfDNA levels and dnDSA features, such as DSA category, MFI and HLA target loci, remains unclear.MethodsWe analyzed dd-cfDNA levels in 75 kidney transplant recipients who developed dnDSA post-transplant. dnDSA were categorized as “true”, “possible”, or “false” based on bead reactivity patterns and HLA typing. dd-cfDNA was assessed alongside dnDSA detection and sequential follow-up samples in a subgroup.Results“True” dnDSA showed significantly higher dd-cfDNA levels compared to “possible” and “false” groups. …”
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Shoulder Pain in Competitive Swimmers: A Multi-Site Survey Study by Brian D. Stirling, Jonathan C. Sum, Lisa Baek, Lori A. Michener, Adam J. Barrack, Angela R. Tate

“…Further research should investigate shoulder pain prevention programs, and surveillance methods are recommended to identify symptomatic swimmers who may benefit from referral to prevent further pain and disability…”
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Exploring physical activity preferences and motivation in long-term cardiac prevention: An Austrian cross-sectional survey. by Hannah McGowan, Johanna Gutenberg, Veronika Leitner, Kathrin Mühlhauser, Aliz Breda, Michael Fischer, Sebastian Globits, Vincent Grote, David Kiesl, Karl Mayr, Michael Muntean, Andrea Podolsky, Josef Niebauer, Rik Crutzen, Stefan Tino Kulnik

“…Five CR centres in Austria posted 500 questionnaires to former CR patients who had completed CR approximately three years prior, and 117 patients (23%) responded. …”
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Dietary factors associated with anaemia among pregnant women attending antenatal care clinics in Sekota town, Northern Ethiopia: a facility-based cross-sectional study by Kassahun Ayele, Meron Demisew

“…This study assessed the dietary factors associated with anaemia among pregnant women attending antenatal care clinics in Sekota town, Northern Ethiopia.Methods A facility-based cross-sectional study was conducted from June to August 2021 among 367 pregnant women who were selected using systematic random sampling techniques. …”
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Prevalence of metal implants among US adults aged 40 years and older by Qiu-Fu Wang, Yu-Chen Tang, Hao-Ran Liao, Miao Lei, Wei Dong, Ze-Yu Liu, Jie Hao, Zhen-Ming Hu

“…This study conducted a serial cross-sectional analysis of US adults aged ≥ 40 years who participated in the National Health and Nutrition Examination Survey (NHANES) (2015–2016 and 2017–March 2020). …”
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The use of emergency medical services for palliative situations in Western Cape Province, South Africa: A retrospective, descriptive analysis of patient records by C Gage, B Spies, K Crombie, L Gwyther, W Stassen

“…All patient records of those who arrived at the hospitals between 1 January 2020 and 31 December 2020 via EMS conveyance leading to palliative care provision were included in the study. …”
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Risk reduction in SARS-CoV-2 infection and reinfection conferred by humoral antibody levels among essential workers during Omicron predominance. by James Hollister, Cynthia Porter, Ryan Sprissler, Shawn C Beitel, James K Romine, Jennifer L Uhrlaub, Lauren Grant, Young M Yoo, Ashley Fowlkes, Amadea Britton, Lauren E W Olsho, Gabriella Newes-Adeyi, Sammantha Fuller, Pearl Q Zheng, Manjusha Gaglani, Spencer Rose, Kayan Dunnigan, Allison L Naleway, Lisa Gwynn, Alberto Caban-Martinez, Natasha Schaefer Solle, Harmony L Tyner, Andrew L Philips, Kurt T Hegmann, Sarang Yoon, Karen Lutrick, Jefferey L Burgess, Katherine D Ellingson

“…Among those with previous infections, the point estimates of risk reduction associated with antibody levels was greater for those with three vaccine doses compared to those who were unvaccinated.…”
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Functional Outcome of Arthroscopic Management of Anterior Cruciate Ligament Injury using Four-strand Hamstring Tendon Graft: A Prospective Cohort Study by R Kavin Kumar, M Mohan, C Rishab, L Sabari Vaasan

“…Materials and Methods: This prospective cohort study was conducted at SRM Medical College and Hospital, Chennai, Tamil Nadu, India, including 33 patients with Grade II and Grade III ACL tears with or without associated meniscal injuries, who underwent ACL reconstruction using a four-strand hamstring tendon graft. …”
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Clinical and radiological evaluation of the Bristow–Latarjet procedure in patients with 30 or more years of follow-up by Arnaldo Amado Ferreira Neto, MD, PhD, Mauro Emilio Conforto Gracitelli, MD, PhD, Jorge Henrique Assunção, MD, PhD, Fernando Brandão de Andrade e Silva, MD, PhD, Verônica Yulin Prieto Chang, MD, Eduardo Angeli Malavolta, MD, PhD

“…Patients with recurrent anterior dislocation of the shoulder who underwent the Bristow–Latarjet procedure were included and followed-up clinically for at least 30 years. …”
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The Influence of Occupational Therapy on College Students’ Home Physical Exercise Behavior and Mental Health Status under the Artificial Intelligence Technology by Chao SONG, G. E. Sha, Wanxiang Yao, Linhai YANG

“…This indicated that the students who liked family physical exercise were less likely to suffer from depression. …”
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Impact of Disease Activity on the Quality of Life of Crohn’s Disease Patients by T Michael Vallis, Geoffrey K Turnbull

“…A sample of 39 CD patients who were assessed using well validated measures of disease activity and disease-specific quality of life is reported. …”
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Prevalence of Diabetes and Cardiovascular Comorbidity in the Canadian Community Health Survey 20022003 by Frank Mo, Lisa M. Pogany, Felix C.K. Li, Howard Morrison

“…Data included 127,610 individuals who participated in the 2.1 cycles of the Canadian Community Health Survey (CCHS) in 2002—2003. …”
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Safety profile of EZH2 inhibitors for cancer: a systematic review and meta-analysis by Zhou Zhao, Xiufeng Chen, Huayang Pang, Yan Shi, Hao Sun

“…Results Our systematic review and meta-analysis included 22 studies encompassing 1,002 patients who met the inclusion criteria. TRAEs were commonly observed during EZH2 inhibitor therapy, affecting 86% of patients (95% CI [79–94%]%; I2 = 89.5%). …”
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Fecal methylated syndecan-2 (SDC2) testing for early screening of colorectal cancerous and precancerous lesions: A real-world retrospective study in China by Boyu Qin, Haitao Niu, Lupeng Qiu, Hongfeng Zhou, Peng Lyu

“…Methods: We retrospectively collected data on participants who underwent fecal SDC2 methylation testing from January 1, 2019, to May 30, 2023. …”
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Successful Management of Peri-Implantitis around Short and Ultrashort Single-Crown Implants: A Case Series with a 3-Year Follow-Up by Giorgio Lombardo, Mauro Marincola, Andrea Cicconetti, Miguel Angel Simancas-Pallares, Jacopo Pighi, Jeffrey Lehrberg, Annarita Signoriello, Giovanni Corrocher, Xiomara Serpa-Romero, Luis Armando Vila Sierra, Luisa Arevalo-Tovar, Pier Francesco Nocini

“…The study is a retrospective evaluation of patients suffering from peri-implantitis and those who underwent access flap surgery, concomitant chemical and mechanical decontamination of implant surface, and bone grafting using a self-hardening mixture of bone substitutes and biphasic calcium sulfate. …”
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Revalidation and adaptation of the Menstrual Practice Needs Scale (MPNS) in a cross-sectional survey to measure the menstrual experiences of adult women working in Mukono District,... by Julie Hennegan, Kellogg J Schwab, Natalie G Exum, Simon P S Kibira, Fredrick E Makumbi, Justine N Bukenya, Petranilla Nakamya

“…A survey of 525 working women who had menstruated in the past 6 months (435 working in markets, 45 in schools and 45 working in healthcare facilities) in Mukono District, Uganda was used to test the dimensionality, reliability and validity of the measure.Results The 36 scale items were well understood by the study population. …”
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A clinical study exploring the prediction of microvascular invasion in hepatocellular carcinoma through the use of combined enhanced CT and MRI radiomics. by Jiangfa Li, Wenxiang Song, Jixue Li, Lv Cai, Zhao Jiang, Mengxiao Wei, Boming Nong, Meiyu Lai, Yiyi Jiang, Erbo Zhao, Liping Lei

“…<h4>Methods</h4>A retrospective analysis was conducted on 93 HCC patients who underwent partial hepatectomy. The gold standard for MVI was based on the histopathological diagnosis of the tissue. …”
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Prevalence and Factors Associated with Drooling in Parkinson’s Disease: Results from a Longitudinal Prospective Cohort and Comparison with a Control Group by Diego Santos-García, Teresa de Deus Fonticoba, Carlos Cores Bartolomé, Maria J. Feal Painceiras, Maria Cristina Íñiguez-Alvarado, Silvia Jesús, Maria Teresa Buongiorno, Lluís Planellas, Marina Cosgaya, Juan García Caldentey, Nuria Caballol, Ines Legarda, Jorge Hernández Vara, Iria Cabo, Lydia López Manzanares, Isabel González Aramburu, Maria A. Ávila Rivera, Víctor Gómez Mayordomo, Víctor Nogueira, Víctor Puente, Julio Dotor García-Soto, Carmen Borrué, Berta Solano Vila, María Álvarez Sauco, Lydia Vela, Sonia Escalante, Esther Cubo, Francisco Carrillo Padilla, Juan C. Martínez Castrillo, Pilar Sánchez Alonso, Maria G. Alonso Losada, Nuria López Ariztegui, Itziar Gastón, Jaime Kulisevsky, Marta Blázquez Estrada, Manuel Seijo, Javier Rúiz Martínez, Caridad Valero, Mónica Kurtis, Oriol de Fábregues, Jessica González Ardura, Ruben Alonso Redondo, Carlos Ordás, Luis M. L. López Díaz, Darrian McAfee, Pablo Martinez-Martin, Pablo Mir, Study Group COPPADIS

“…Patients and Methods. PD patients who were recruited from January 2016 to November 2017 (baseline visit; V0) and evaluated again at a 2-year ± 30-day follow-up (V2) from 35 centers in Spain from the COPPADIS cohort were included in this longitudinal prospective study. …”
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