Unsupervised machine learning model for phenogroup-based stratification in acute type A aortic dissection to identify postoperative acute gastrointestinal injury by Yuhu Ma, Xiaofang Yang, Chenxiang Weng, Xiaoqing Wang, Baoping Zhang, Ying Liu, Rui Wang, Zhenxing Bao, Peining Yang, Hong Zhang, Yatao Liu

“…ObjectiveWe aimed to explore the application value of unsupervised machine learning in identifying acute gastrointestinal injury (AGI) after extracorporeal circulation for acute type A aortic dissection (ATAAD).MethodsPatients who underwent extracorporeal circulation for ATAAD at the First Hospital of Lanzhou University from January 2016 to January 2021 were included. …”
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A pelvis MR transformer-based deep learning model for predicting lung metastases risk in patients with rectal cancer by Yin Li, Yin Li, Yin Li, Shuang Li, Shuang Li, Ruolin Xiao, Ruolin Xiao, Xi Li, Yongju Yi, Yongju Yi, Liangyou Zhang, Liangyou Zhang, You Zhou, You Zhou, Yun Wan, Chenhua Wei, Liming Zhong, Liming Zhong, Wei Yang, Wei Yang, Lin Yao, Lin Yao, Lin Yao

“…This study aims to develop and validate a transformer-based deep learning (DL) model based on pelvic MR images, integrated with clinical features, to predict RCLM.MethodsA total of 819 patients with histologically confirmed rectal cancer who underwent preoperative pelvis MRI and carcinoembryonic antigen (CEA) tests were enrolled. …”
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Methods to address functional unblinding of raters in CNS trials by Steven D. Targum, William P. Horan, Vicki G. Davis, Alan Breier, Stephen K. Brannan

“…First, we compared the scores of remote (site-independent) raters, blinded to TEAEs, who listened to audio recorded, site-based Positive and Negative Syndrome Scale (PANSS) interviews. …”
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Chronic Atrophic Gastritis Presenting as Hemolytic Anemia due to Severe Vitamin B12 Deficiency by Amanda M. Woodford, Rabhea Chaudhry, Gabriella A. Conte, Varsha Gupta, Madhurima Anne

“…This case describes a 46-year-old male with no past medical history who presented with chest pain, fatigue, and progressive weakness, found to have hemolytic anemia, ultimately attributed to vitamin B12 deficiency. …”
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Intratumoral oncolytic virus OH2 injection in patients with locally advanced or metastatic sarcoma: a phase 1/2 trial by Lu Zhang, Shu Li, Jing Huang, Yan Wu, Liang Han, Tian Gao, Qingxia Fan, Suxia Luo, Binlei Liu, Lixin Zhou, Xinyu Wang, Ling Jia, Jianhua Shi, Zhichao Tan, Zhengfu Fan, Sijuan Ding, Chujie Bai, Ruifeng Xue, Jiayong Liu

“…Here, we examined the safety and efficacy of OH2 as a single agent or in combination with HX008, an NMPA-approved PD-1 inhibitor, in locally advanced or metastatic sarcoma patients.Methods This multicenter, phase 1/2 trial enrolled patients with injectable sarcoma lesions, who had failed at least 1 or more lines of standard treatment. …”
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Association between the intensity of statin therapy and physical activity 1 year after acute coronary syndrome: a multicentre prospective cohort study in Switzerland by David Nanchen, Stephan Windecker, Isabella Locatelli, Nicolas Rodondi, Lorenz Räber, David Carballo, Francois Mach, Olivier Muller, Baris Gencer, Christian M Matter, Roland Klingenberg, Thomas Lüscher, Alex Boudon

“…Objectives To assess the association between the intensity of statin therapy and the level of physical activity in patients 1 year after an acute coronary syndrome (ACS).Design Prospective cohort study from the Special Program University Medicine-Acute Coronary Syndromes.Setting Four university hospital centres in Switzerland.Participants 2274 patients with a main diagnosis of ACS between 2009 and 2017 who were available for a 1-year follow-up visit 1 year after hospital discharge.Outcome measures Self-reported physical activity was assessed with the International Physical Activity Questionnaire. …”
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Understanding the unique role of community-based para-professionals delivering early childhood development in low-resource contexts: a Delphi study by Emma Claire Pearson, Maxwell Peprah Opoku

“…Abstract Background Community-based para-professionals are trained or untrained professionals who assist in the delivery of health-related care in communities where they live. …”
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Lipids and C-reactive protein predict anhedonia and reward circuit functional connectivity responses to anti-cytokine and dopaminergic therapies in patients with depression by Aditya Singh, Mandakh Bekhbat, David R. Goldsmith, Ngoc-Anh Le, Evanthia C. Wommack, Zhihao Li, Ebrahim Haroon, Jennifer C. Felger

“…To extend our previous findings on relationships between plasma lipids and antidepressant response to anti-cytokine therapy, we explored in secondary analyses whether lipid-related biomarkers similarly predicted change in anhedonia or functional connectivity (FC) in dopamine-rich corticostriatal reward circuitry in medically-stable, depressed patients with a range of inflammation levels (indexed by plasma C-reactive protein [CRP]) who were administered inflammation-targeted therapies. …”
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Academic and Socioсultural Adaptation of Students in Russian Universities by P. A. Ambarova, G. E. Zborovsky, V. S. Nikolskiy, N. V. Shabrova

“…The negative trend of decreasing student activity in the research field compared to the school period of study , as well as the preservation of a high proportion of those who are prone to academic fraud due to the lack of adaptive resources, is shown. …”
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IN THE WAKE OF PUGACHEV’S REBELLION: EXPERIENCE IN ORAL HISTORY by N. V. Shevtsov

“…The author of this article visited the places, where the events took place, and repeated the journey of A.S. Pushkin, who visited the region in 60years after Pugachev's Rebellion. …”
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The risk of malnutrition as a predictor of arrhythmia recurrence after catheter ablation in patients with paroxysmal non-valvular atrial Fibrillation and heart failure with preserv... by Zixi Zhang, Cancan Wang, Qiming Liu, Yichao Xiao, Jiabao Zhou, Keke Wu, Yunying Huang, Zeying Zhang, Shiping Liu, Qiuzhen Lin

“…<h4>Methods</h4>We conducted a retrospective analysis of 204 patients with paroxysmal non-valvular AF and HFpEF who underwent radiofrequency or cryoballoon ablation. …”
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Demonstration Exam in Continuing Entrepreneurial Education within the VET and HE Systems by O. A. Romanova, K. V. Anisimova

“…The data also included 4 in-depth semi-structured interviews with VET students who have successful experience in confirming the results of mastered entrepreneurial competencies. …”
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Characterisation of internal tremors and vibration symptoms by Harlan M Krumholz, Mitsuaki Sawano, Richa Sharma, Tianna Zhou, Dorothy Massey, Anna D Baker, Diana Berrent Güthe, Nick Güthe, Suzanne Pincus Shidlovsky, Liza Fisher, Connor B Grady, Cesar Caraballo

“…Objectives To describe the experiences of patients who have postacute sequelae SARS-CoV-2 infection with internal vibrations and tremors as a prominent component, we leveraged the efforts by Survivor Corps, a grassroots COVID-19 patient advocacy group, to gather information from individuals belonging to its Facebook group with a history of COVID-19 suffering from vibrations and tremors.Setting and design A narrative analysis was performed on 140 emails and 450 social media comments from 140 individuals collected as a response to a call to &gt;180 000 individuals participating in Survivor Corps between 15 July and 27 July 2021. …”
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Correlations between Left Ventricular and Left Atrial Function Assessed by Speckle Tracking Echocardiography in Patients with Treated Well-Controlled Arterial Hypertension by Beata Uziębło-Życzkowska, Paweł Krzesiński

“…LA contractile, conduit, and reservoir function, together with echocardiographic signs of LV diastolic function and LV global longitudinal strain (LV GLS), were assessed in 101 patients with treated, well-controlled AH who met the standard criteria of normal LV ejection fraction (LVEF) and normal LV diastolic function. …”
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Effects of Different Organic Fertilizers on Yield and Yield-Related Characteristics in Black Cumin (Nigella sativa L.) Cultivation Under the Ecological Conditions of Tokat, Türkiye... by Abdulkadir Acar, Yasin Bedrettin Karan

“…This finding reveals that the use of organic fertilizer in black cumin cultivation is an important alternative for farmers who want to both increase yield and prefer a natural production method.…”
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The real-world efficacy and toxicity of first-line paclitaxel and cisplatin with bevacizumab in platinum-naïve primary stage IVB cervical cancer by Junhwan Kim, Eun-Byul Park, Shin-Wha Lee, Jeong-Yeol Park, Dae-Yeon Kim, Dae-Shik Suh, Jong-Hyeok Kim, Yong-Man Kim, Ju-Hyun Kim

“…Materials and methods: We retrospectively reviewed patients with stage IVB cervical cancer who received paclitaxel-cisplatin-bevacizumab as first-line treatment between July 2015 and December 2021 at Asan Medical Center, Korea. …”
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A Pilot Study Investigating the Expression Levels of Pluripotency-Associated Genes in Rectal Swab Samples for Colorectal Polyp and Cancer Diagnosis and Prognosis by Ryan Wai-Yan Sin, Dominic Chi-Chung Foo, Deepak Narayanan Iyer, May Sau-Yee Fan, Xue Li, Oswens Siu-Hung Lo, Wai-Lun Law, Lui Ng

“…Further analysis showed that higher c-MYC and CXCR4 level was detected in normal subjects who developed polyps after 5-6 years, in comparison with subjects with no lesion developed, and the AUC of the c-MYC and CXCR4 panel increased to 0.88 (p<0.001), with sensitivity and specificity of 84.4% and 92.3%, respectively, when these patients were included in the polyp group. …”
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Screening and prognostic roles of renal volumetry and scintigraphy in the assessment of living kidney transplant donors, considering the early recovery of the residual renal functi... by Shunta Hori, Mitsuru Tomizawa, Kuniaki Inoue, Tatsuo Yoneda, Kenta Onishi, Yosuke Morizawa, Daisuke Gotoh, Yasushi Nakai, Makito Miyake, Kazumasa Torimoto, Nobumichi Tanaka, Kiyohide Fujimoto

“…Methods We retrospectively reviewed the medical charts of 175 consecutive LKDs who underwent donor nephrectomy (DN) at our institution between 2006 and 2022. …”
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Thyrotoxicosis due to Gestational Trophoblastic Disease: Unmet Needs in the Management of Gestational Thyrotoxicosis by Kalyan Mansukhbhai Shekhda, Vladislav Zlatkin, Bernard Khoo, Eleni Armeni

“…In this report, we present two cases (Patient 1: 43 years, Patient 2: 31 years) who came to emergency department following a history of vaginal spotting, palpitations, and hyperemesis. …”
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Comparing short‐term outcome after implantation of the HeartWare® HVAD® and the Abbott® HeartMate 3® by Rene Schramm, Armin Zittermann, Michiel Morshuis, Michael Schoenbrodt, Ellen vonRoessing, Vera vonDossow, Andreas Koster, Henrik Fox, Kavous Hakim‐Meibodi, Jan F. Gummert

“…Methods and results We retrospectively analysed preoperative and post‐operative patient data of all 106 patients, who received a HeartMate 3 (HM3) at our centre between 2014 and 2018. …”
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