Intranasal racemic ketamine maintenance therapy for patients with treatment-resistant depression: a naturalistic feasibility study by Katelyn Halpape, Raelle Pashovitz, Annabelle Wanson, Monika Hooper, Evyn M. Peters

“…Participants were adult inpatients with treatment-resistant depression who had been successfully treated with intranasal racemic ketamine in hospital and were being referred for outpatient maintenance therapy with an intranasal racemic ketamine spray, administered at a specialized community treatment centre. …”
Get full text

Does therapy with immunosuppressive drugs improve gastrointestinal symptoms in patients with systemic sclerosis? by Oliver Distler, Cosimo Bruni, Suzana Jordan, Carina Mihai, Muriel Elhai, Rucsandra Dobrota, Alexandru Garaiman, Mike Oliver Becker, Lea Stamm, Sherif Ismail, Norina Zampatti, Aurora Maria Tatu

“…We aimed to identify an association between immunosuppressive therapy and the the severity of GI symptoms, measured by the University of California at Los Angeles/Scleroderma Clinical Trial Consortium Gastro-Intestinal Tract instrument 2.0 (GIT).Methods We selected patients with SSc who had at least two visits (further referred to as ‘baseline’ and ‘follow-up’) with completed GITs, within an interval of 12±3 months. …”
Get full text

Ibuprofen-Induced Multiple Fixed Drug Eruption Confirmed by Re-Challenge: A Case Report and Literature Review by Yoshihito Mima, Masako Yamamoto, Hiyo Obikane, Yuta Norimatsu, Ken Iozumi

“…<b>Case Presentation:</b> Herein, we report the case of a 23-year-old man who developed ibuprofen-induced multiple FDE. The diagnosis was confirmed by detecting a rash immediately following ibuprofen administration, and histopathological findings were consistent with FDE. …”
Get full text

Assessment of factors implicated in bone fusion after percutaneous endoscopic lumbar intervertebral fusion by Zheng Huang, Xialin Li, Weihong Yi, Junfeng Gong, Yue Zhou, Yu Tang

“…Methods: This single-center retrospective study reviewed the medical records of 96 patients who underwent single-level PELIF for degenerative pathologies between 2018 and 2020. …”
Get full text

1-year data on patient-reported outcome is enough after surgery for degenerative cervical myelopathy: a cohort study from the Swedish Spine register by Lovisa Gerdhem, Anna MacDowall, Paul Gerdhem

“…Similar findings were seen in individuals who also had 5-year data. Bland–Altman plots indicated good agreement between 1- and 2-year data, and between 1- and 5-year data and were without proportional bias. …”
Get full text

High‐risk cytogenetic abnormalities in multiple myeloma: PETHEMA‐GEM experience by Veronica González‐Calle, Paula Rodriguez‐Otero, Maria J. Calasanz, Manuela Guijarro, Joaquin Martínez‐López, Laura Rosiñol, Miguel T. Hernández, Ana I. Teruel, Mercedes Gironella, Albert Oriol, Javier de laRubia, Ana P. González‐Rodríguez, Joan Bargay, Felipe deArriba, Luis Palomera, Marta‐Sonia González‐Pérez, Anna Sureda, Enrique Ocio, Juan J. Lahuerta, Joan Bladé, Jesus F. San Miguel, Maria V. Mateos, Norma C. Gutiérrez

“…Del(17p) was linked to poor prognosis using a cut‐off level of ≥20% positive cells, without any impact of higher cut‐off in prognosis, except for patients with clonal fraction ≥80% who had a dismal outcome. Cosegregation of cytogenetic abnormalities patients worsened the prognosis in t(4;14) patients but not in patients with del(17p), which retained its adverse prognosis even as a solitary abnormality. …”
Get full text

Effectiveness of Traditional Healers in Program to Control Leprosy in Nagan Raya District in Aceh by Teuku Alamsyah, Said Usman, Mutia Yusuf, Said Devi Elvin

“…The main object of this study, which used a quasi-experimental design, was to find out and to improve the treatment of leprosy patients by the Tabib who treat them there. Data was gathered using a questionnaire with an interview and the intervention was to provide training and a pocket book about leprosy and how to detect, control, and manage it there and the role that the Tabib can play in controlling leprosy in the future. …”
Get full text

The Feasibility and Safety of the Clip-and-Snare Method with a Prelooping Technique for Gastric Submucosal Tumors Removal: A Single-Center Experience (with Video) by Qi Tang, Rui-Yue Shi, Jun Yao, Li-Sheng Wang, De-Feng Li

“…We retrospectively enrolled a matched group of 86 patients who received ESD combined with CSM-PLT or ESD alone from July 2010 to July 2020. …”
Get full text

Multimodal Imaging Characteristics of ADRP in a Family with p.Thr58Arg Substituted RHO Mutation by Misty Ruppert, John Pyun, K. V. Chalam, David Sierpina

“…Additionally, we compare the patient’s phenotypic findings to those of her offspring, who was also affected by adRP. Results. The 58-year-old female and her son with symptoms of nyctalopia and decreased vision showed macular pigmentary changes in a bull’s-eye pattern along with bone spicules in periphery with retinal atrophy. …”
Get full text

Determining barriers and facilitators to engagement for families in a family-based, multicomponent healthy lifestyles intervention for children and adolescents: a qualitative study by Yvonne C Anderson, Paul L Hofman, Cervantée EK Wild, Ngauru T Rawiri, Esther J Willing

“…Semistructured, home-based interviews were conducted and thematically analysed with peer debriefing for validity.Participants Families were selected through stratified random sampling to include a range of levels of engagement, including those who declined their referral, with equal numbers of interviews with Indigenous and non-Indigenous families.Results Three interactive and compounding determinants were identified as influencing engagement in Whānau Pakari: acute and chronic life stressors, societal norms of weight and body size and historical experiences of healthcare. …”
Get full text

Use Of Anti-Epileptics For Seizure Prophylaxis After Traumatic Brain Injury In The Pediatric Population by Aroosh Khan, Sidra Tul Muntaha, Hammad Ayaz, Afrah Tariq, Huma Mughal

“…A total of 160 children aged from 2 to 18 years who presented with traumatic brain injury within 24 hours of trauma were included. …”
Get full text

Hermann Karl von Keyserlingk and the Recognition of the Russian Imperial Title by the Holy Roman Empire in 1745–1746 by M. A. Petrova

“…The author managed to find out, it was Keyserlingk who had the idea to send the official representative of Russia to the election of the Emperor in Frankfurt in 1745 and then in 1746 to the Imperial Diet in Regensburg, which approved the election results. …”
Get full text

Association between Bioelectrical Impedance Parameters, Magnetic Resonance Imaging Muscle Parameters, and Fatty Liver Severity in Children and Adolescents by Kyungchul Song, Eun Gyung Seol, Eunju Lee, Hye Sun Lee, Hana Lee, Hyun Wook Chae, Hyun Joo Shin

“…Methods: Children and adolescents who underwent BIA and liver magnetic resonance imaging between September 2022 and November 2023 were included. …”
Get full text

Une famille transatlantique : les Fleuriau by Jacques de Cauna

“…We can clearly see today, through the new context of cultural studies, how French families dealt with colonial contingencies characterized in particular by the presence of Blacks and free men of color in La Rochelle (he brought back with him two of his daughters of color and gave plantations and slaves to his sons of color who stayed back in Saint-Domingue) with an undeniable flexibility in the adaptation of their traditional strategies regarding kinship, marriage, godparents, and inheritance.The family of La Rochelle is in a way remodelled in the light of the Domingan slave society, but still seeking to preserve the interests of its members. …”
Get full text

Anticoagulation Status and Outcome in Cerebral Venous Thrombosis: A Single-Center Retrospective Study from South India by Deepak Menon, Manisha Gupta, Sangeeth Thuppanattumadam Ananthasubramanian, Karthik Kulanthaivelu, Pritam Raja, Subasree Ramakrishnan, Sangeetha Seshagiri Karnam, Jitender Saini, PR Srijithesh, Girish B Kulkarni

“…Methods: We retrospectively collected data of patients admitted with CVT over a 5-year period, who had a minimum of 6 months of clinical follow-up and three or more prothrombin time international normalized ratio (INR) values spread over 6 months. …”
Get full text

A Nomogram Based on Apelin-12 for the Prediction of Major Adverse Cardiovascular Events after Percutaneous Coronary Intervention among Patients with ST-Segment Elevation Myocardial... by Enfa Zhao, Hang Xie, Yushun Zhang

“…Information on 464 patients with STEMI who performed PCI procedures was included. After removing patients with incomplete clinical information, a total of 460 patients followed for 2.5 years were randomly divided into evaluation (n = 324) and validation (n = 136) cohorts. …”
Get full text

A Study of Hypothyroidism in Chronic Kidney Disease (CKD) Patients by Sudharsanan V, Prabhu Shankar S, Viknesh V

“…The study involved 237 CKD patients who provided informed consent and met inclusion criteria. …”
Get full text

From colostomy creation to full enteral feeding in neonates with an anorectal malformation: evaluating the role of central venous access by D. Huijgen, I. K. Schokker-van Linschoten, H. P. Versteegh, C. E. J. Sloots

“…This retrospective cohort study aimed to evaluate the postoperative course regarding enteral feeding tolerance and the necessity for a central venous access device (CVAD) after colostomy formation in newborns with ARMs.MethodsThe files of neonates with ARMs who underwent colostomy formation between January 2014 and August 2023 were reviewed. …”
Get full text

Associations between Driving Status, Frequency of Transport use after Driving Cessation, and Social Frailty among Middle-Aged and Older Adults by Tatsuya Fukuei, Shoma Akaida, Yoshiaki Taniguchi, Daijo Shiratsuchi, Yuto Kiuchi, Mana Tateishi, Yukari Aishita, Ryota Kuratsu, Hyuma Makizako

“…Conclusions Participants who neither drive nor take transport showed significant associations with increased social frailty. …”
Get full text

Effectiveness of home-based walking exercise for patients with peripheral artery disease and intermittent claudication: a systematic review and meta-analysis by Zheng Xu, Jing Chuo, Xiaoqin Zhao

“…Objective This study aimed to assess the effect of home-based exercise interventions on walking performance in patients with peripheral artery disease (PAD) and intermittent claudication (IC).Design Systematic review and meta-analysis.Data sources We searched the Medline, Web of Science, Embase, Scopus and Cochrane Library databases to identify randomised controlled trials of patients with PAD and IC published in English up to August 2024.Eligibility criteria Randomised controlled trials of patients who participated in home-based exercise interventions and were assessed for walking performance were eligible for inclusion. …”
Get full text