Atezolizumab, bevacizumab, pemetrexed and platinum for EGFR‐mutant NSCLC patients after EGFR TKI failure: A phase II study with immune cell profile analysis by Shang‐Gin Wu, Chao‐Chi Ho, James Chih‐Hsin Yang, Shu‐Han Yu, Yen‐Feng Lin, Shu‐Chin Lin, Bin‐Chi Liao, Ching‐Yao Yang, Yen‐Ting Lin, Chong‐Jen Yu, Ya‐Ting Chuang, Wei‐Yu Liao, Kah Yi Yap, Weng Si Kou, Jin‐Yuan Shih

“…Furthermore, immune cell profiling may aid in identifying patients who may benefit from this approach. Key points The combination regimen yielded promising efficacy in NSCLC patients after EGFR‐TKI resistance, particularly those with PD‐L1‐positive tumours. …”
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Assessment of Ganglion Cell Complex and Peripapillary Retinal Nerve Fiber Layer Changes following Cataract Surgery in Patients with Pseudoexfoliation Glaucoma by Ahmed A. Abdelghany, Moataz A. Sallam, Abdallah A. Ellabban

“…They were divided into two groups; the first group included patients with PEXG and cataract who underwent phacoemulsification (pseudophakic group; n = 40 eyes). …”
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Baska Mask versus I-gel in Spontaneously Breathing Anaesthetised Patients: A Randomised Clinical Study by Bhagyavardhan Botta, Yogarajan Ramalingam, Grishma Robba, Tanya Elizabeth, Kala Balasubramanian, Selvamani Subramanian, Senthil Kumar Vannivedu Santhnam, Kavyasri Morampudi

“…Materials and Methods: A prospective randomised single-blinded study was conducted in the Department of Anaesthesiology, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India from October 2019 to October 2020 on 60 American Soceity of Anaesthesiology (ASA) physical status I and II patients, aged between 18-65 years, who were scheduled for minor surgical procedures while spontaneously breathing under general anaesthesia. …”
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How can competencies in minor surgery in general practice be increased? Assessing the effect of a compact intervention in postgraduate training: a mixed-methodsstudy by Joachim Szecsenyi, Jonas D Senft, Katja Krug, Simon Schwill, Aaron Poppleton, Dorothee Reith, Sandra Stengel

“…Semi-structured interviews were performed after 9 months.Setting In 2019, a 2-day voluntary seminar focussing on minor surgery/injuries was offered on 13 occasions by educators from KWBW Verbundweiterbildungplus (Competence Centre for Postgraduate Medical Education Baden-Württemberg).Participants All enrolled GP trainees were offered participation. GP trainees who did not attend a seminar (non-attendees) were recruited for CG after the 13th intervention.Intervention Attendees took part in an interactive, GP-oriented short course incorporating 270 min of focused minor surgery/injuries training (compact intervention) on the second day of the 2-day seminar.Results 326 GP trainees (IG: n=257; CG: n=69) participated in the study. 17 attendees were interviewed. …”
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Endogenous sex hormone levels are associated with the revised Framingham Stroke Risk Profile in postmenopausal women: a longitudinal study in a Swedish cohort by Kristin Ottarsdottir, Åsa Tivesten, Claes Ohlsson, Ying Li, Margareta Hellgren, Ulf Lindblad, Bledar Daka

“…The participants were physically examined in 2002–2005 and sex hormones were analysed with liquid chromatography-tandem mass spectrometry assay (LC-MS/MS). Women who were ≥55 years old, with estradiol levels below 20 pg/mL, not using hormonal therapy, and with no self-reported history of stroke, were included (N = 133). …”
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Development and Validation of Risk Stratification for Heart Failure After Acute Coronary Syndrome Based on Dynamic S100A8/A9 Levels by Jie Ma, Ke Ma, Jing Chen, Xinying Yang, Fei Gao, Hai Gao, Hui Zhang, Xin‐Liang Ma, Jie Du, Ping Li, Yulin Li

“…Methods and Results This prospective study included 3 independent cohorts of patients with ACS who received reperfusion therapy. The discovery cohort was divided into 2 subgroups: the longitudinal subgroup (n=264) with serum S100A8/A9 levels measured at admission and on days 1, 2, 3, and 4 postadmission, respectively, and the 2‐point subgroup (n=798) with S100A8/A9 levels measured at admission and on day 1 postadmission, respectively. …”
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Karakteristik Penderita Dispepsia Fungsional yang Mengalami Kekambuhan di Bagian Ilmu Penyakit Dalam RSUP Dr. M. Djamil Padang, Sumatera Barat Tahun 2011 by Yui Muya, Arina Widya Murni, Rahmatina B Herman

“…The objective of this study was to investigate the characteristics of hospitalized patients with dyspepsia who have a relapse at Dr M. Djamil Hospital Padang, West Sumatra in 2011. …”
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Eating Habits, Anxiety and Depression in Patients with Irritable Bowel Syndrome: Clinical and Laboratory Comparisons by O. V. Gaus, M. A. Livzan

“…All individuals included in the study were assessed for diet and eating habits using the WHO CINDI program questionnaire, “Information on Nutrition and Eating Behavior”, the severity of anxiety and depression according to the HADS questionnaire, the level of specific anxiety in relation to gastrointestinal symptoms according to the VSI questionnaire, quality of life according to the IBS-QoL questionnaire. …”
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Biomarkers of gastric atrophy at stomach cancer by A. V. Belkovets, S. A. Kurilovich., Yu. I. Ragino, L. V. Scherbakova, O. B. Cheremisina, N. V. Cherdyntseva, N. A. Andryushina, M. I. Voyevoda

“…Original investigation was designed as «case series», that included 85 patients with SC (48 m and 37 f, mean age 61.2±13,6 years) who were consistently referred to two medical institutions. …”
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Ion Chromatography Based Urine Amino Acid Profiling Applied for Diagnosis of Gastric Cancer by Jing Fan, Jing Hong, Jun-Duo Hu, Jin-Lian Chen

“…Forty three urine samples were collected from inpatients and healthy adults who were divided into 4 groups. Healthy adults were in group A (n=15), early gastric cancer inpatients in group B (n=7), and advanced gastric cancer inpatients in group C (n=16); in addition, two healthy adults and three advanced gastric cancer inpatients were in group D (n=5) to test models. …”
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Long-term outcomes of robot-assisted versus minimally invasive esophagectomy in patients with thoracic esophageal cancer: a propensity score-matched study by Toru Sakurai, Akihiro Hoshino, Kenta Miyoshi, Erika Yamada, Masaya Enomoto, Junichi Mazaki, Hiroshi Kuwabara, Kenichi Iwasaki, Yoshihiro Ota, Shingo Tachibana, Yutaka Hayashi, Tetsuo Ishizaki, Yuichi Nagakawa

“…Methods This retrospective study included 86 patients with thoracic esophageal cancer who underwent RAMIE or MIE at our hospital from June 2010 to December 2016. …”
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Is it Time to Normalize Scapular Dyskinesis? The Incidence of Scapular Dyskinesis in Those With and Without Symptoms: a Systematic Review of the Literature by Paul A. Salamh, William J. Hanney, Trey Boles, Daniel Holmes, Alex McMillan, Austin Wagner, Morey J. Kolber

“…More revealing is the number of asymptomatic individuals who do present with SD, suggesting that SD may be a normal finding among nearly half of the asymptomatic population…”
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Non‐invasive telemedical care in heart failure patients and stroke: post hoc analysis of TIM‐HF and TIM‐HF2 trials by Serdar Tütüncü, Marcus Honold, Kerstin Koehler, Oliver Deckwart, Friedrich Koehler, Karl Georg Haeusler

“…A history of PAOD (OR 2.7, 95% CI 1.2–6.2; P = 0.02) and the highest tertile (OR 3.0, 95% CI 1.1–8.3) of N‐terminal pro‐brain natriuretic peptide (NT‐proBNP) on enrolment were associated with stroke/TIA during follow‐up. In patients who suffered acute stroke or TIA during follow‐up, echocardiography was part of the diagnostic workup in only 56% after hospital admission. …”
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Assessment Of Heavy Metals Concentration and Pollution Indices Of Surface Water In Enerhen River, Warri South LGA, Delta State, Nigeria by A. O. Egai, M. Paaru

“…Data obtained show that the result indicated the concentration of Zinc 0.065mg/l - 0.190mg/l, Pb (0.003mg/l -0.142mg/l), Cu (0.081mg/l - 0.213mg/l), Cd (0.02mg/l - 0.282mg/l, Cr (0.041mg/l - 0.171mg/l), Fe (0.162mg/l - 0.278mg/l) and Ni (0.104mg/l - 0.762mg/l)  comparison with WHO 2012 permissible limit the probed water sample falls within the allowable concentration of the standard except the  concentration of lead (Pb) in SW1, SW2, SW4 and SW5 which is a  concern because it exceeded the allowable limit, lead is considered toxic to human at higher concentrations . …”
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Changing Attitudes Towards Research Through a Course-based Undergraduate Research Experience by Keith Brazendale, Michael Rovito, Jeanette Garcia

“…Wilcoxon signed rank tests for paired data were conducted and Mann-Whitney U tests assessed whether there were any differences between students who completed the course face-to-face versus online. …”
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CT-based skeletal muscle loss predicts long term prognosis in patients with distal cholangiocarcinoma undergone pancreaticoduodenectomy by Guangzhen Qu, Shao-Cheng Lyu, Yong Zhang, Kun Gao, Chuanguo Zhou

“…We aimed to explore the value of skeletal muscle changes in the prognosis of distal cholangiocarcinoma (DCC) patients undergone pancreaticoduodenectomy (PD). Patients who underwent PD for DCC between 2015 and 2023 were included in this study. …”
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Development and assessment of a mortality risk prediction nomogram model for pneumocystis disease in ICU within 28 days by Yiru Weng, Tingting Zhou, Honghua Ye

“…Abstract To develop and assess a nomogram predictive model for evaluating the 28-day mortality risk in patients diagnosed with Pneumocystis who have been admitted to the intensive care unit (ICU). …”
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Discrimination of Radiologists' Experience Level Using Eye-Tracking Technology and Machine Learning: Case Study by Stanford Martinez, Carolina Ramirez-Tamayo, Syed Hasib Akhter Faruqui, Kal Clark, Adel Alaeddini, Nicholas Czarnek, Aarushi Aggarwal, Sahra Emamzadeh, Jeffrey R Mock, Edward J Golob

“…These results signify the potential impact of the proposed method for identifying radiologists’ level of expertise and those who would benefit from additional training. …”
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The position of Lithuanian parties towards Poland in 1920-1926: from modus vivendi to permanent confrontation by Andrius Grodis

“…However, despite the hostility to Poland entrenched in society, the leaders of political parties who envisioned the greatest danger to the state's independence from Soviet Russia and Germany actively sought pacific means of resuming the historical capital of the state and for ways of friendly affiliation of interstate relations.  …”
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La escritura borrada de las mujeres. Itinerarios lectores inclusivos y (re)construcción del canon poético / The erased writing of women. Inclusive reading itineraries and (re)const... by Remedios Sánchez-García, Pablo Aparicio-Durán

“…The aim is to integrate into the baccalaureate curriculum significant female authors who, despite their quality and value, have been overshadowed even though they should legitimately be included in order to compose a valid textual corpus that responds to the truth of the historical-literary, seeking exclusively to improve the training of readers. …”
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