Potential alternative and novel biomarkers for paediatric MAFLD: exploratory evidence from a Chinese cohort by Fan Yang, Mengyuan Hu, Lulian Xu, Xiaowei Zheng, Lihong Zhu, Le Zhang, Haoyang Zhang

“…Results Out of 1,108 participants who completed all examinations (N biomarker = 91), 113 participants were diagnosed with MAFLD (prevalence: 14.99% in boys and 5.18% in girls). 27 biomarkers that were strongly correlated with diagnostic biomarkers were identified as alternative biomarkers. …”
Get full text

Impact on CD4+ CD25High-CD127low regulatory T (Treg) cells of neoadjuvant therapy for rectal cancer patients by Liu Maoxi, Liu Haiyi

“…Materials and Methods: Rectal cancer patients who had received neoadjuvant therapy prior to surgery at Shanxi Cancer Hospital between January and September 2018 were enrolled in the study. …”
Get full text

Strength training for osteoporosis prevention during early menopause (STOP-EM): a pilot study protocol for a single centre randomised waitlisted control trial in Canada by Leigh Gabel, Lauren A Burt, Christina J Alexander, Leah Kaluta, Patrick W Whitman, Emma O Billington

“…However, this has not been investigated in perimenopausal and early postmenopausal women who are in the midst of the menopausal transition.Methods and analysis This study is a 9-month randomised controlled feasibility trial evaluating a HiRIT programme in perimenopausal and early postmenopausal women. …”
Get full text

Prenatal genetic detection in foetus with gallbladder size anomalies: cohort study and systematic review of the literature by Yimo Zeng, Rong Hu, Jian Lu, Yiming Qi, Dan Chen, Chaoxiang Yang, Jing Wu

“…Objectives The aim of the study was to evaluate the detection rate of genetic abnormalities in cases of foetal gallbladder (FGB) size abnormalities to determine whether these abnormalities justify prenatal diagnosis.Methods Two hundred and twenty-seven foetuses with gallbladder (GB) size anomalies who underwent prenatal diagnosis between January 2015 and June 2024 were included in the study. …”
Get full text

Axial spondyloarthritis in India: determining the delay in diagnosis, impact on work productivity, and attitude of patients toward treatment by Kamini Narendra Reddy, Asawari Raut, Pravin Patil

“…Methodology: A cross-sectional study was conducted on 100 axSpA patients who fulfilled the ASAS criteria. Ethical approval was obtained. …”
Get full text

EGOISM AS A WAY OUT OF EXISTENTIAL CRISIS FOR A PERSON IN DISABILITY SITUATION by N. A. Mrinskaya

“…The theory that divides the being of a person into various types (ordinary, ultimate, and being beyond the bounds) is able to most fully structure the concept of egoism in the being of a person who has disability. Originality. I made an attempt to prove the positive role of egoism in a situation related to the body transformation into new conditions. …”
Get full text

Associations between neutrophil-percentage-to-albumin ratio level and all-cause mortality and cardiovascular disease-cause mortality in diabetes population by Geng Shen, Yuting Liu, Can Zhou, Wei Luo, Yun-xiao Yang, Shuai Guo, Jiayi Yi, Lin Wang, Wei Li, Zhao-gong Zhi, Xiu-huan Chen, Chen Li, Yanyan Jin, Hai Gao

“…Methods This prospective cohort study included 3602 adults aged 20 or above who were diagnosed with diabetes by the American Diabetes Association criteria in the US National Health and Nutrition Examination Survey (NHANES) database from 1999 to 2016, and followed up until 2019. …”
Get full text

Transition zone-based prostate-specific antigen density for differentiating clinically significant prostate cancer in PI-RADS score 3 lesions by Yongming Jin, Fei Chen, Gang Xu, Chaogang Wei, Congsong Dong

“…Between September 2018 and August 2023, patients who underwent mpMRI examination and scored as PI-RADS 3 were queried from our institution. …”
Get full text

Hip and Groin Problems in Female Team-Sport Athletes: A Cross-Sectional Study by Juan Diego Stadelmann, Freddy Reichmann, Romana Franceschini-Brunner, Andrea Mosler, Nicola A. Maffiuletti, Mario Bizzini

“… # Methods Female athletes who participated in various sports underwent preseason assessment of isometric hip adduction and abduction strength, with pain levels recorded during respective contractions, and self-reported function on the Copenhagen Hip and groin Outcome Score (HAGOS). …”
Get full text

Quadriceps Strength following Anterior Cruciate Ligament Reconstruction: Normative Values based on Sex, Graft Type and Meniscal Status at 3, 6 & 9 Months by Nicole A. Schwery, Michael T. Kiely, Christopher M. Larson, Corey A. Wulf, Christie S. Heikes, Ryan W. Hess, M. Russell Giveans, Braidy S. Solie, Chrisopher P. Doney

“… # Methods One hundred and twenty-five participants who underwent ACLR with either a hamstring tendon (HT), bone-patellar tendon-bone (BPTB) or quadriceps tendon (QT) autograft were included. …”
Get full text

Effects of Microsatellite Instability on the Clinical and Pathological Characteristics of Colon Cancer and the Diagnostic Accuracy of Preoperative Abdominal CT Scans by Rıdvan Yavuz, Orhan Aras, Hüseyin Çiyiltepe, Onur İlkay Dinçer, Ahmet Şükrü Alparslan, Tebessüm Çakır

“…<b>Results</b>: A total of 131 CC patients who had undergone surgical resection were analyzed. …”
Get full text

Risk Factors for Single and Multiple Recurrences for Endoscopic Retrograde Cholangiopancreatography and Open Choledochotomy in Treating Choledocholithiasis by Yao Wu, Ying Zhang, Xiao Meng Jiang, Chen Jing Xu, Yan Yan Wang, Jin Yuan Gu, Yi Li, Shun Fu Xu

“…A total of 1255 patients with choledocholithiasis who underwent ERCP or OCT were retrospectively studied. …”
Get full text

Efficacy and safety of anti-thrombotic therapy after surgical mitral valve repair: a scoping review by Jian Ye, Jenny Chen, Hazal Ece Babadagli, Ricky Turgeon, Erica HZ Wang

“…This scoping review aimed to summarise current evidence on the safety and efficacy of anti-thrombotic therapy after MVr, identify knowledge gaps and propose a future study design.Methods We searched MEDLINE, Embase, Cochrane Central Register of Controlled Trials, Clinicaltrials.gov, the WHO International Clinical Trials Registry Platform and bibliographies of included trials, guidelines and other reviews from inception to 17 September 2024. …”
Get full text

Impact of leadership behaviour on physician well-being, burnout, professional fulfilment and intent to leave: a multicentre cross-sectional survey study by Mihriye Mete, Charlotte Goldman, Tait Shanafelt, Daniel Marchalik

“…Physicians in the top tertile were also 48% less likely to be burned out (OR=0.52, 95% CI: 0.45 to 0.61) and reported 66% lower intent to leave (OR=0.34, 95% CI: 0.26 to 0.44). Individuals who rated their supervisor’s leadership in upper tertiles relative to lower tertiles exhibited lower levels of burnout (18% vs 35% vs 47%, p&lt;0.001), and intent to leave (16% vs 24% vs 50% p&lt;0.001).Conclusion Perceived leadership behaviours have a strong relationship with burnout, professional fulfilment and intent to leave among physicians. …”
Get full text

Role of the very low frequencies of the renal oxygen saturation signal in acute kidney injury in newborns with perinatal asphyxia by Daniel Botero-Rosas, Sergio Agudelo-Pérez, Sergio Agudelo-Pérez, Gloria Troncoso, Maria C. Gómez, Eduardo Tuta-Quintero

“…This component demonstrated good predictive ability for AKI (ROC curve 0.77, 95% CI 0.63–0.90).ConclusionAmong neonates with perinatal asphyxia who developed AKI, a lower power of the very-low-frequency component in FFT (approximately 0.01 Hz) was observed on the second day of therapeutic hypothermia. …”
Get full text

Care Burden and Coping Strategies among Caregivers of Paediatric HIV/AIDS in Northern Uganda: A Cross-Sectional Mixed-Method Study by Ibrahim Mujjuzi, Paul Mutegeki, Sarah Nabuwufu, Ashim Wosukira, Fazirah Namata, Patience Alayo, Sharon Bright Amanya, Richard Nyeko

“…This places an enormous demand and care burden on the caregivers who often struggle to cope in various ways, some of which may be maladaptive. …”
Get full text

Early and Midterm Outcome of Surgical Repair of Total Anomalous Pulmonary Venous Connection by Sandy Adel, Karam Mosallam Eisa, Mohamed Adel Elgamal, Asmaa Gaber Rizk

“…Patients and methods: This prospective study was carried out on 27 TAPVC patients who underwent different single-stage surgical techniques. …”
Get full text

The absolute number of circulating Treg cells is reduced in difficult-to-treat RA patients and is ameliorated by low-dose IL-2 by Huanhuan Yan, Huanhuan Yan, Huanhuan Yan, Xiaoyu Zi, Xiaoyu Zi, Xiaoyu Zi, Huer Yan, Xiaoying Zhang, Xiaoying Zhang, Xiaoying Zhang, Jie Bai, Jie Bai, Jie Bai, Chong Gao, Xiaofeng Li, Xiaofeng Li, Xiaofeng Li, Caihong Wang, Caihong Wang, Caihong Wang

“…This study focused on the uniqueness of D2T RA lymphocyte subsets and the feasibility of low-dose IL-2 therapy.MethodsParticipants included 1,042 RA patients who were divided into three groups according to the presence or absence of treatment and their response to treatment in the last 6 months—new group, treated group, and D2T group—and 339 healthy controls (HCs). …”
Get full text

Physical activity and exercise recommendations for people receiving dialysis: A scoping review. by Kelly Lambert, Courtney J Lightfoot, Dev K Jegatheesan, Iwona Gabrys, Paul N Bennett

“…<h4>Conclusion</h4>Future guidelines should include specific guidance regarding physical activity, safety precautions, and timing and intensity of exercise for individuals who undertake dialysis. Collaborative multidisciplinary guideline development and appropriate exercise counselling may lead to increased participation in physical activity and exercise and facilitate better patient outcomes.…”
Get full text

Using the Hospital Frailty Risk Score to predict length of stay across all adult ages. by Huda Kutrani, Jim Briggs, David Prytherch, Claire Spice

“…We calculated HFRS for patients who had been previously admitted to the hospital within the previous 2 years. …”
Get full text