Limited Diagnostic Value of miRNAs in Early Trauma-Induced Liver Injury: Only miRNA-122 Emerges as a Late-Phase Marker by Jason-Alexander Hörauf, Amit Singh, Maika Voth, Hamed Moheimani, Cora Rebecca Schindler, Borna Relja, Liudmila Leppik, Ingo Marzi, Dirk Henrich

“…This study investigates whether specific liver-related microRNAs (miRNAs) are released into the circulation in trauma patients with liver injury and whether they can indicate liver damage in the early phase after major trauma. <b>Methods</b>: A retrospective analysis of prospectively collected data and blood samples from 26 trauma patients was conducted. …”
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Codeswitching – Ergebnisse einer Studie in der albanischen Sprachgruppe in Deutschland und der Schweiz by Naxhi Selimi, Basil Schader, Andrea Cantieni

“…Der vorliegende Beitrag ermöglicht Einblicke in die bilinguale Praxis und das damit zusammenhängende Codeswitching. Hierzu wurden Personen aller drei Generationen (N=120) befragt. …”
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Disproportionate, differential and targeted treatment: people who use drugs’ experiences of policing during the COVID-19 pandemic by Shelley Walker, Kasun Rathnayake, Paul Dietze, Peter Higgs, Bernadette Ward, Margaret Hellard, Joseph Doyle, Mark Stoove, Lisa Maher

“…Studies globally have revealed how the expansion of policing powers produced significant collateral damage for marginalized populations, including people from low-income neighboorhoods, Indigenous Peoples, sex workers, and people from culturally diverse backgrounds. …”
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Die Lobé-Wasserfälle, ein außergewöhnliches geokulturelles Erbe an der kamerunischen Küste zwischen nachhaltigem Tourismus und der Bewahrung kultureller Identitäten by Mesmin Tchindjang, Marcel Hugues Etoga

“…Dabei soll berücksichtigt werden, wie der nachhaltige Tourismus in diese Küsten- und Badegebiete integriert wurde, welcher Logik die Akteure gefolgt sind und welchen Beitrag sie damit geleistet haben sowie schließlich auch welche Probleme diese Entwicklung mit sich gebracht hat. …”
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Urine proteomics defines an immune checkpoint-associated nephritis signature by Cassian Yee, Jamie S Lin, James P Long, Shailbala Singh, Yanlan Dong

“…Delayed or incorrect diagnosis of ICI-AIN is particularly detrimental, as over 50% of patients are at risk of permanent renal damage. Thus, there is an urgent need for non-invasive biomarkers that can rapidly and accurately distinguish ICI-AIN from other causes of AKI.The urine and plasma proteome contain actively secreted proteins that provide real-time insights into dynamic physiological processes. …”
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MT2A promotes angiogenesis in chronically ischemic brains through a copper–mitochondria regulatory mechanism by Ni Mo, Chuyang Tai, Yang Yang, Cong Ling, Baoyu Zhang, Lei Wei, Cian Yao, Hui Wang, Chuan Chen

“…HUVEC activity and mitochondrial structure and function were detected to explore the ability of MT2A to alleviate CPO-induced damage. Finally, a rat model of 2-vessel occlusion plus encephalo-myo-synangiosis (2VO + EMS) with CPO was established to test the proangiogenic effect of MT2A through the copper–mitochondria regulatory mechanism in chronically ischemic brains. …”
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The use of Geographic Information Systems as innovative tools for sustainable development strategies and enhancing the efficiency of forest sector entities by Lutsiv Nataliia, Pavlo Chukhna

“…The study confirms that the use of GIS and mathematical modeling methods allows for achieving maximum economic benefits and developing measures to reduce the environmental damage from forest exploitation. The conclusions emphasize the importance of using GIS to integrate ecological and economic parameters into forestry strategies in order to enhance their efficiency, as well as for participation in international programs supporting sustainable forest management practices, such as REDD+.…”
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Trichinella spiralis excretory/secretory proteins mediated larval invasion via inducing gut epithelial apoptosis and barrier disruption. by Qi Qi Lu, Wen Wen Zheng, Zhao Yu Zhang, Pei Kun Cong, Xin Guo, Yao Zhang, Xin Zhuo Zhang, Shao Rong Long, Ruo Dan Liu, Zhong Quan Wang, Jing Cui

“…<h4>Conclusions</h4>T. spiralis IIL ESP induced gut epithelial apoptosis, reduced the TJs expression, damaged gut epithelial integrity and barrier function, and promoted larval invasion. …”
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Human Umbilical Cord Mesenchymal Stem Cells Attenuate Ocular Hypertension-Induced Retinal Neuroinflammation via Toll-Like Receptor 4 Pathway by Shangli Ji, Jie Xiao, Jian Liu, Shibo Tang

“…Glaucoma is characterized by progressive, irreversible damage to the retinal ganglion cells (RGCs) and their axons. …”
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Optimizing selenium-enriched yeast supplementation in laying hens: Enhancing egg quality, selenium concentration in eggs, antioxidant defense, and liver health by Longfei Zhang, Jianmin Zhou, Uchechukwu Edna Obianwuna, Cheng Long, Kai Qiu, Haijun Zhang, Xiaolong Qi, Shugeng Wu

“…However, higher supplementation levels (6.0 mg/kg) resulted in liver damage, underscoring the importance of careful dosage consideration.…”
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Mitochondrial Gene Expression of Three Different Dragonflies Under the Stress of Chlorpyrifos by Yuxin Chen, Ziwen Yang, Zhiqiang Guo, Lemei Zhan, Kenneth B. Storey, Danna Yu, Jiayong Zhang

“…CPF exhibits its toxicity primarily through the inhibition of the acetylcholinesterase (AChE) enzyme, while mitochondrial damage and dysfunction have also been observed. The present study quantified the transcript levels of mitochondria protein-coding genes (mtPCGs) using quantitative real-time polymerase chain reaction (<i>RT-qPCR</i>) in samples of larvae of three dragonfly species (<i>A. parthenope</i>, <i>E. elegans</i>, and <i>G. confluens</i>) under different levels of CPF stress. …”
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A Prospective Observational Study to Establish a Correlation Between Tinnitus and Hearing Loss by Anshu Chopra, Madhurima Bannerjee, Sanjoy Ghosh

“…Both tinnitus and sensorineural hearing loss can occur when there is damage throughout the auditory pathway from the inner ear to auditory cortex. …”
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Genetic diversity of VIR Raphanus sativus L. collections on aluminum tolerance by A. B. Kurina, I. A. Kosareva, A. M. Artemyeva

“…The effect of various concentrations on the vital activity of plants was revealed: a 66-mM concentration of AlCl3 · 6Н2О had a weak toxic effect on R. sativus accessions slowing down root growth; 83 mM contributed to a large differentiation of the small radish accessions and to a lesser extent for radish; 99 mM inhibited further root growth in 13.0 % of small radish accessions and in 7.3 % of radish and had a highly damaging effect. AlCl3 · 6Н2О at a concentration of 99 mM allowed us to identify the most tolerant small radish and radish accessions that originate from countries with a wide distribution of acidic soils. …”
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Adaption oder Anpassung? Umweltbewusstsein in der Region um den Plattensee/Balaton (Adaptation or a Change in Attitude? Environmental Awareness in the Region of Lake Balaton) by Magdolna Leveleki

“…Our sociology working group at Pannon University carried out a research during the years of 2013-2014 related to the social effects of climate change, entitled „Regional effects of extreme weather conditions due to climate change and the possibilities of reducing damage in the upcoming decades”. The Hungarian eco-philopsophical literature highights two main issues concerning the adaptation and a change in values and in attitude related to climate change. …”
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Leucocytosis and Asymptomatic Urinary Tract Infections in Sickle Cell Patients at a Tertiary Hospital in Zambia by Taonga Musonda, Mildred Zulu, Mulemba Samutela, Annie Kalonda, Hamakwa Mantina, Pauline Okuku, Musalula Sinkala, Panji Nkhoma

“…It is associated with several complications including an altered blood picture and damage in multiple organs, including the kidneys. …”
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Surgical Treatment Patterns, Healthcare Resource Utilization, and Economic Burden in Patients with Tenosynovial Giant Cell Tumor Who Underwent Joint Surgery in the United States by Feng Lin, Winghan J. Kwong, Sherry Shi, Irina Pivneva, Eric Q. Wu, John A. Abraham

“…**Background:** Tenosynovial giant cell tumors (TGCT) are rare and locally aggressive neoplasms in synovium, bursae, and tendon sheaths, which cause pain, joint dysfunction, and damage to the affected joints. **Objective:** To evaluate the surgical patterns and economic burden among patients with TGCT who underwent joint surgery in the United States. …”
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Pain in pancreatitis: issue and ways out by A. V. Okhlobystin

“…Histological study frequently reveals signs of neural damage, inflammatory mediators often can act as pain mediators. …”
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Nutritional Status and Educational Performance of School-Aged Children in Lalibela Town Primary Schools, Northern Ethiopia by Muluken Ayalew, Alemayehu Bayray, Abate Bekele, Simegnew Handebo

“…Failing to provide good nutrition puts them at risk for missing out on meeting that potential and leads to long-term irreversible damage to cognitive development. However, taking action today to provide healthier choices in schools can help set students up for a successful future full of possibilities. …”
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Study on the Mechanism of Black Phosphorus Nanosheets Loading Sr2+ Used in Photothermal Antibacterial Treatment by Ma G, Li B, Diao J, Zhang Y, Zhang B, Wu D, Gui H, Zhong J, Zhu H, Zhang D

“…Finally, the transcriptomic results suggest that bacteria death may be related to membrane destruction, metabolic disorders, and transport damage. HE staining and Gram staining also showed that inflammation was significantly alleviated after laser treatment.Conclusion: These findings propose a great solution for bacterial infection and also enrich the theoretical framework supporting the application of BP-Sr in the field of antibiosis. …”
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Copper Super-Dosing Improves Performance of Heat-Stressed Broiler Chickens through Modulation of Expression of Proinflammatory Cytokine Genes by Sudipto Haldar, Amrita Kumar Dhara, Sayantani Sihi Arora, Arpana Verma Mukherjee, Arup Nayak

“…Continuous exposure to high ambient temperatures brings about a number of oxidative damages in chickens. Copper (Cu), an active component of a number of antioxidative defence components, should arrest these changes to take place although that may not be possible under the standard dosing regimen followed by the industry. …”
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