Characterization of demethylating DNA glycosylase ROS1 from Nicotiana tabacum L. by D. V. Petrova, N. V. Permyakova, I. R. Grin, D. O. Zharkov

“…While in mammals active demethylation is based on targeted regulated damage to mC in DNA followed by the action of repair enzymes, demethylation in plants is performed by specialized DNA glycosylases that hydrolyze the N-glycosidic bond of mC nucleotides. …”
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Randomized Clinical Trial of Intraocular Pressure-Lowering Medications on Preventing Spikes in Intraocular Pressure Following Intravitreal Anti-Vascular Endothelial Growth Factor I... by Piriya Soomsawasdi, Kulawan Rojananuangnit, Eakkachai Arayangkoon, Ratchada Chantiwas, Sureeporn Pengrungreungwong, Nontakorn Preawsampran, Natnaree Tinpowong, Rujira Samakhararaksakul, Kanokwan Katkingkaew, Natthapuch Seekhum, Wanwisa Sathim

“…Mean IOP measurements between baseline and 30 min in the brimonidine/timolol two-drop regimen were not significantly different: 13.72 ± 4.63 vs 15.11 ± 4.39 mmHg, p = 0.096. …”
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Echinacea purpurea (L.) Moench crude extract combined with citric acid inactivates Cronobacter sakazakii isolated from powdered infant formula by Peng Fei, Yaping Yu, Chen Liang, Ruxue Fang, Yujun Jiang, Ling Guo

“…Cell membrane hyperpolarization, damaged cell membrane integrity, improved cell membrane permeability, decreased bacterial protein and DNA levels, increased and then decreased intracellular ROS contents, and deformed and ruptured cell morphology were found in C. sakazakii treated by EE combined with CA, and these phenomena were more pronounced than in C. sakazakii treated by EE or CA alone. …”
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Quarantine nematode species and pathotypes potentially dangerous for domestic potato production: populations diversity and the genetics of potato resistance by N. V. Mironenko, T. A. Gavrilenko, A. V. Khiutti, O. S. Afanasenko

“…Potatoes are affected by more than 30 types of parasitic nematodes, but the review focuses on the most harmful representatives of genera that cause great damage to potato production: Globodera, Ditylenchus, Nacob bus and Meloidogyne. …”
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The Life Mission Theory IV. Theory on Child Development by Soren Ventegodt, Joav Merrick

“…Many modifications result in a child with severely damaged self-confidence, self-worth, and poor performance. …”
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Morphopathology of the Prussian carp (Carassius auratus gibelio Bloch, 1782) liver under the effect of allyl acetate by M. Koziy

“…To assess the liver parenchyma of Prussian carp based on the analysis of histological parameters of the organ, to establish the level of the effect of alylacetate on the physiological status of fish and the degree of their damage. To determine the prospects for using the obtained results in ichthyological and ecological practice. …”
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Knowledge, attitudes, and beliefs regarding acute coronary syndrome in patients with type 2 diabetes: a cross-sectional study by Mohammad Amerzadeh, Mahdie Bahrami, Mojtaba Senmar, Zahra Hosseinkhani, Zahra Shafiei Kisomi

“…In the knowledge section, the highest percentage of correct responses was related to awareness of facilities in the hospital to reduce heart attack-related damages (62.3%) and familiarity with the symptoms of arm or hand numbness (43.41%). …”
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Experimental Study on Nanomechanical Properties of Yunnan Red-Bed Mudstone by Xian Ye, Yongcai Liu, Haibin Xue, Guo Li, Jin Xing

“…Under the same loading and holding time conditions, sample 3 (Nanhua) has the deepest residual indentation, and SEM tests show that the damage to indentation is obvious. Sample 2 (Jingdong) has the shallowest residual indentation. …”
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Integrated bioinformatics analysis identified cuproptosis-related hub gene Mpeg1 as potential biomarker in spinal cord injury by Dandan Mao, Qi Chen, Shuolan Tong, Zixia Xu, Guofeng Yu, Chuan Chang, Yao Lv

“…In summary, targeting Mpeg1, as well as cuproptosis and immune cell infiltration, holds promise as a potential strategy for reducing spinal cord tissue damage and promoting recovery after SCI. These findings provide valuable insights for future therapeutic interventions.…”
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Estimation of median LC50 and toxicity of environmentally relevant concentrations of thiram in Labeo rohita by Sana Alam, Gulnaz Afzal, Riaz Hussain, Hafiz Muhammad Ali, Amtul Sami, Rabbiah Manzoor Malik, Raheela Jabeen, Farid Shokry Ataya, Kun Li

“…Moreover, comet assay revealed significant (p < 0.05) DNA damage in the isolated cells of kidneys, heart and brain at higher doses (80 μg/L and 120 μg/L) of thiram that was further confirmed by histo-pathological alterations in these tissues. …”
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The change rule of smoke dispersion and temperature evolution in fires within lithium iron phosphate energy storage prefabricated cabin by ZHANG Yin, QIN Chaoqun, TIAN Shuangshuang, GE Zhichao, DONG Jun, ZHANG Xiaoxing

“…This perfluorohexane fire extinguishing system, with a sprinkler intensity of 20 L/(min ·m2), a sprinkler angle of 120°and a particle size of 50 μm, can successfully controls fires and mitigates fire damage. The research results in the article can provide theoretical guidance for the distributed deployment strategy in energy storage prefabricated cabin and fire safety design of monitoring and warning devices.…”
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New evidence on the nephrotoxicity of fine particulate matter: Potential toxic components from different emission sources by Fu-Jen Cheng, Chien-Er Huang, Pei-Shih Chen, Yu-Lun Tseng, Chung-Shin Yuan, Ching-Shu Lai

“…However, the specific mechanisms and components causing renal damage remain unclear. PM2.5 was collected from an industrial and a rural area. …”
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Effect of Hyperthermic Intraperitoneal Perfusion Chemotherapy Combined with Radical Surgery and Capecitabine on Stage III Gallbladder Cancer by Sulai Liu, Zhendong Zhong, Weimin Yi, Zhangtao Yu, Zhihua Zhang, Guoyi Xia, Bo Jiang, Yinghui Song, Chuang Peng

“…There was no liver and kidney damage in the two groups after surgery. The platelets in the HIPEC group were less than those in the control group (P<0.05). …”
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Biochemical and Histopathological Studies of Key Tissues in Healthy Male Wistar Rats Fed on African Yam Bean Seed and Tuber Meals by Omena Bernard Ojuederie, John Adebayo Ajiboye, Olubukola Oluranti Babalola

“…The consumption of 100% unprocessed AYB seeds caused liver and kidney damage in rats due to increased levels of aspartate aminotransferase (5.04 ± 1.62 U L−I), alanine aminotransferase (8.46 ± 2.43 U L−I), and lipid peroxidation (0.27 ± 0.02-unit mg−1protein). …”
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Effects of carob rich-polyphenols on oxidative stress markers and physical performance in taekwondo athletes by Nawel Gaamouri, Hassane Zouhal, Katsuhiko Suzuki, Mehrez Hammami, Aloui Ghaith, El Hafedh El Mouhab, Anthony C. Hackney, Ismail Laher, Omar Ben Ounis

“…Excessive exercise can induce cell damage and impair muscle function by generating oxidative stress. …”
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Catastrophe Mechanism of Stress-Fissure Coupling Field in Mining Close Distance Seams in Southwest China by Suo Jie, Li Zhen-hua, Huang Cun-han, Cao Zheng-zheng, Xu You-lin, Chen Zu-guo

“…When the 1402 working face advances to 350 m, the top of vertical karst caves in the middle of the model produces extrusion damage, forming a penetrating water inrush passage. …”
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Assessment of fire blight resistance in apple clonal rootstocks using molecular markers by I. N. Shamshin, M. V. Maslova, N. V. Drenova, M. L. Dubrovsky, O. V. Parusova

“…The degree of rootstock damage by fire blight affects the resistance of the variety–rootstock combination. …”
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Systemic Overexpression of GDF5 in Adipocytes but Not Hepatocytes Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver in Mice by Yan Yang, Wenting Zhang, Xiaohui Wu, Jing Wu, Chengjun Sun, Feihong Luo, Zhou Pei

“…Systemic overexpression of GDF5 in adipose tissue in vivo significantly reduced HFD-induced NAFLD liver damage in mice. The overexpression of GDF5 in hepatocytes failed to improve lipid accumulation and inflammation-related reactions induced by mixed fatty acids, suggesting that the protective effect of GDF5 in NAFLD was mainly due to the reduction in adipose tissue and improvements in metabolism. …”
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The multidisciplinary approach to the treatment of paediatric chronic pain: a qualitative analysis through focus groups by Aldana Paola Ercolano, Sabrina Galvan, Tessa Louise Marchesan, Alessia Gavioli, Gerardo Papa, Mariarita Todaro, Lidia Berforini D’Aquino, Alessia Zanatta, Andrea Vianello

“…Pain, defined by the International Association for the Study of Pain (IASP), as an unpleasant sensory and emotional experience associated with actual or potential tissue damage. It becomes chronic when it persists beyond three months, affecting quality of life and clinical prognosis. …”
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Restructuring of Global Pharmaceutical Supply Chains after COVID-19 by N. A. Volgina

“…The aim of this paper is to identify possible firm strategies and models for restructuring pharmaceutical chains aimed at increasing their resilience in response to the damaging effects of Covid-19. We suppose that the resilience of the chain as a whole depends on the resilience of its separate links, and we show that the restructuring of pharmaceutical chains takes place in the form of the so-called “link” restructuring (restructuring of separate links of the chain). …”
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