IGF2BP2 Regulates the Progression of Alzheimer's Disease Through m6A‐Mediated NLRP3 Inflammasome by Wu Jingrui, Yang Haihui, Yan Jinjin, Fang Le

“…Conclusion Knockdown of IGF2BP2 inhibit neuronal damage and pyroptosis in the hippocampus cells, and improve cognitive function in AD partly through m6A‐mediated NLRP3 inflammasome.…”
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Ameliorative Effect of Hovenia dulcis Fruit Pedicel Polysaccharides on Alcohol-Induced Intestinal Injury in Mice Investigated Using 16S rRNA Sequencing and Metabolomics by ZHANG Yuchao, ZHU Sijie, LIU Liangyu, WANG Jianyun, ZHANG Jiaxin, SU Zexiong, CHEN Jiangyan, LIU Xudong

“…In summary, HDPs has the potential to ameliorate alcohol-induced intestinal damage by improving intestinal barrier function through the modulation of the gut microbiota and bile acid metabolism. …”
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Targeting NF-kappaB-inducing kinase shapes B-cell homeostasis in myasthenia gravis by Xiaoyu Huang, Zhouao Zhang, Zhouyi Wang, Tiancheng Luo, Mingjin Yang, Xinyan Guo, Xue Du, Tianyu Ma, Yong Zhang

“…Intraperitoneal injection of B022 ameliorated the severity of EAMG rats, and reduced proportion of pathogenic B and T cell subsets, antibody levels and postsynaptic membrane damage. Conclusions Targeting NIK with small molecule kinase inhibitors can effectively shape B cell homeostasis, and exhibit protective effects in the EAMG rat model, which may be an effective novel treatment strategy for MG.…”
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Magnetic Resonance Imaging of Contrast-Induced Acute Renal Injury and Related Pathological Alterations In Vivo by Yanfei Li, Dafa Shi, Haoran Zhang, Xiang Yao, Ke Ren

“…The microscopic appearance presents the strongest renal damage in CI-AKI mice that existed between 12 h (P<0.0001) and 24 h (P<0.05) after contrast medium (CM) injection. …”
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KGB Struggle with Antisoviet Manifestation in Lithuania and Abroad: People's Discreditation by Kristina Burinskaitė

“…In a struggle with inner enemies, KGB used the method of discreditation, which aims to damage authority, good name of an opponent, and trust of society in him by leaking out or interpreting negatively the facts of his life and activity in order to suppress their activity, lower the number of supporters and to justify the repression. …”
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Infection‐Related Hospitalization and Incident Heart Failure: The Atherosclerosis Risk in Communities Study by Rebecca L. Molinsky, Amil Shah, Melana Yuzefpolskaya, Bing Yu, Jeffrey R. Misialek, Bruno Bohn, David Vock, Richard MacLehose, Barry A. Borlaug, Paolo C. Colombo, Chiadi E. Ndumele, Junichi Ishigami, Kunihiro Matsushita, Pamela L. Lutsey, Ryan T. Demmer

“…Background The immune response to infections may become dysregulated and promote myocardial damage contributing to heart failure (HF). We examined the relationship between infection‐related hospitalization (IRH) and HF, HF with preserved ejection fraction, and HF with reduced ejection fraction. …”
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Relevance of superoxide dismutase type 1 to lipoid pneumonia: the first retrospective case-control study by Yinan Hu, Yanhong Ren, Yinzhen Han, Zhen Li, Weiqing Meng, Yuhui Qiang, Mengyuan Liu, Huaping Dai

“…Abstract Background Lipoid pneumonia (LP) is a rare disease caused by the accumulation of lipids and lipid-laden macrophages in the alveoli inducing damage. LP is difficult to differentiate from other similar diseases without pathological evidence, such as upper respiratory tract infection (URTI), pneumonia, cryptogenic organizing pneumonia (COP), pulmonary alveolar proteinosis (PAP), lung mucinous adenocarcinoma and pulmonary edema. …”
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Efficient Excavation and Support Cooperation Technology for Surrounding Rock of Deep Buried Long-Distance and Large Section Gob-Side Roadway: A Case Study by Houqiang Yang, Changliang Han, Nong Zhang, Xudong Li, Yitao Liu, Wentao Liu, Kai Song, Yuxin Guo, Wei Yao

“…Supposed that upon the heading face support is completed, the next excavation-support cycle is quickly started during the early stage of stress adjustment, and the time effect can be fully utilized to alleviate the disturbance intensity of the advanced abutment stress in the heading face, as well as reduce the damage of rock mass. This paper puts forward the time-effect collaborative control countermeasures of the roof and rib in gob-side roadway of “hole collapse anchor cable of solid coal rib lag construction and waits for pressure relief and rapid excavation-support cycle in the heading face.” …”
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Detecting, Monitoring, and Analyzing the Surface Subsidence in the Yellow River Delta (China) Combined with CenterNet Network and SBAS-InSAR by Zhenjin Li, Zhiyong Wang, Wei Liu, Xing Li, Maotong Zhou, Baojing Zhang

“…Long-term industrial activities tend to cause surface subsidence and damage to ground facilities and local ecological environment. …”
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Analysis of the Impact of Fault Mechanism Radiation Patterns on Macroseismic Fields in the Epicentral Area of 1998 and 2004 Krn Mountains Earthquakes (NW Slovenia) by Andrej Gosar

“…The radiation patterns of both events were studied to explain their possible impact on the observed variations in macroseismic fields and damage distribution. Radiation amplitude lobes were computed for three orthogonal directions: radial P, SV, and SH. …”
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Syphilis Infection During Pregnancy: The Possible Effect on the Course of Pregnancy and Fetal Outcomes—A Case Report and Literature Review by Dovile Kielaite, Saule Januskiene, Virginija Paliulyte

“…., premature birth, of congenital infections with associated bacterial meningitis, respiratory distress syndrome, multiple organ damage, and insufficient weight. Such associations with many adverse pregnancy outcomes as well as congenital syphilis and neonatal defects are often avoidable. …”
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Structural Covariance of the Ipsilesional Primary Motor Cortex in Subcortical Stroke Patients with Motor Deficits by Xinyuan Chen, Mengcheng Li, Naping Chen, Huimin Lai, Ziqiang Huang, Yuqing Tu, Qunlin Chen, Jianping Hu

“…However, little is known about the interactions between the damaged primary motor cortex (M1) and other brain regions in stroke patients with motor deficits. …”
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Exploring coastal climate adaptation through storylines: Insights from cyclone Idai in Beira, Mozambique by Henrique M.D. Goulart, Panagiotis Athanasiou, Kees van Ginkel, Karin van der Wiel, Gundula Winter, Izidine Pinto, Bart van den Hurk

“…We use cyclone Idai in Beira, Mozambique, as a case study of a powerful cyclone that has caused extensive damage to a coastal city and imagine how these impacts would change under multiple scenarios. …”
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Radioprotective Effects of Vitis vinifera L. Seed against Radiation-Induced Short-Term Memory Loss in Young Adult Wistar Rats by Ayomide Abe, Fatai Balogun, Olugbenga Ayannuga

“…This issue primarily arises from ionizing radiation generating reactive oxygen species, contributing to chronic oxidative stress that can damage brain cells. While dose fractionation, intensity-modulated radiotherapy, and neural stem cell transplantation have demonstrated limited effectiveness, natural plant antioxidants offer a promising alternative. …”
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Determining the Temporal and Spatial Effects of Human Induced Interventions on Some Water Quality Parameters of Murgul Creek by Şenol Osmanaoğlu, Mehmet Özalp

“…It is known that human-induced damaging factors on the quality and quantity of water produced by river watersheds cause some negative consequences (pollution, changes in water regime, decreases in flow rate, etc.). …”
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Experimental prosopis management practices and grassland restoration in three Eastern African countries by René Eschen, Ketema Bekele, Yohana Jumanne, Staline Kibet, Fernadis Makale, John Richard Mbwambo, Berhanu Megersa, Mahamood Mijay, Francis Moyo, Linus Munishi, Mickfanaka Mwihomeke, Winnie Nunda, Moses Nyangito, Arne Witt, Urs Schaffner

“…Abstract Woody species have been introduced in many parts of the world to provide economic benefits, but some of those species are now among the worst invaders, causing widespread economic and environmental damage. Management of woody species to restore original ecosystem services, such as biodiverse grassland that can provide fodder and sequester carbon, are needed to limit the impacts of alien species. …”
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Investigation of Forest Fire Effects on Morel (Morchella spp.) Mushroom Proliferation: A Case Study of Alucra, Giresun by Bülent Sağlam, Mustafa Aybar, Fatma Nur Yılmaz

“…We conclude that forest fires, one of the most important natural disasters that cause damage in the forests, can also be used within the scope of morel mushroom production. …”
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HINT1 suppression protects against age-related cardiac dysfunction by enhancing mitochondrial biogenesis by Michio Sato, Tsuyoshi Kadomatsu, Jun Morinaga, Yuya Kinoshita, Daisuke Torigoe, Haruki Horiguchi, Sumio Ohtsuki, Shuji Yamamura, Ryoko Kusaba, Takanori Yamaguchi, Goro Yoshioka, Kimi Araki, Tomohiko Wakayama, Keishi Miyata, Koichi Node, Yuichi Oike

“…Finally, decreased HINT1 expression due to Caren overexpression antagonized age-related declines in mitochondrial biogenesis, ameliorating age-related cardiac dysfunction, exercise intolerance, and exercise-induced cardiac damage and subsequent death of mice. Conclusion: Our findings suggest that mitochondrial biogenesis in cardiomyocytes decreases with age and could underlie cardiac dysfunction, and that the Caren-HINT1-mitochondrial biogenesis axis may constitute a mechanism linking CR to resistance to cardiac aging. …”
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3-Acetyldeoxynivalenol induces pyroptosis in leydig cells via METTL3-mediated N6-methyladenosine modification of NLRP3 by Yangyun Wang, Chaoliang Shi, Wei Jiao, Xiaoxiang Wan

“…Our results demonstrate that 3-ADON exposure leads to substantial testicular damage in vivo and significantly reduces cell viability while increasing mortality in TM3 cells in vitro (P = 0.012). …”
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Serum fatty acid-binding protein 3 levels differentiate active from inactive myositis and correlate with response to therapy by Latika Gupta, Sanjukta Majumder, Amita Aggarwal, Ramnath Misra, Able Lawrence

“…Background: Delay in the diagnosis of idiopathic inflammatory myopathies (IIMs) and resultant muscle wasting leads to a setting, wherein conventional biomarkers fail to identify inflammation amid damage. Fatty acid-binding protein 3 (FABP3) has a selective location and function lending unique potential as a specific biomarker in IIM. …”
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