Synaptotagmin-1 attenuates myocardial programmed necrosis and ischemia/reperfusion injury through the mitochondrial pathway by Teng Sun, Jialei Li, Shuang Wang, Yu Han, Xiangyu Tao, Min Yuan, Zhijie Jing, Ting Liu, Yuehong Qi, Siqi Liu, Yanlin Feng, Jiasong Chang, Lan Zhou, Lijuan Gao, Jianyun Shi, Ruihong Ning, Jimin Cao

“…We showed here that Syt1 expression was significantly down-regulated in mice I/R injured heart tissues, H2O2-challenged cardiomyocytes and hypoxia/reoxygenation (H/R)-damaged cardiomyocytes. Enforced expression of Syt1 significantly inhibited myocardial necrotic cell death and interstitial fibrosis, and improved cardiac function in mice subjected to I/R operation. …”
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An Unusual Case of Peripheral Nerve Vasculitis by S. Wang, Arsany A., D. Feinstein, P. Traisak, H. Eid, M. Karpoff

“…The EMG showed severe peripheral nerve damage and denervation, which is unusual for ANCA-associated systemic vasculitis.…”
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TAK-242 improves sepsis-associated acute kidney injury in rats by inhibiting the TLR4/NF-κB signaling pathway by Yan-mei Xia, Yu-qian Guan, Ji-fang Liang, Wei-dong Wu

“…The pathological changes in the kidneys were observed by hematoxylin-eosin staining, and tubular damage was scored. Oxidative stress-related factors, mitochondrial dysfunction-related indicators in each group were measured; the levels of inflammatory factors in serum and kidney tissue of rats were examined. …”
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Study of possible intrauterine infection of goat fetus with caprine arthritis-encephalitis virus by V. Yu. Koptev, N. A. Shkil, N. Yu. Balybina, T. N. Belenkova

“…The disease is quite widespread in our country, causing serious economic damage to the backyard and family-operated farm owners. …”
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Structural Characterization and Antioxidant Activity in Vivo of Polysaccharides from the Leaves of Hippophae rhamnoides L. by Niannian SONG, Yuxin YI, Xiaoping ZHANG, Bo YANG, Mangsier SAINAWAER, Abuduwaili AYITUXUN

“…The HE staining results indicated that HRLP had protective effect on liver and kidney tissue cells and structure damage in mice. The medium dose group of HRLP could increase the number of gut microbiota species in mice and promote the synthesis of short-chain fatty acids in the body. …”
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Perioperative complications following spinal fusion in idiopathic scoliosis: A review of 825 cases from the German Spine Registry (DWG-register) – Perioperative complications in id... by Juan Manuel Vinas-Rios, Vincent J. Heck, Fatima Azucena Medina-Govea, Mario Alberto Islas-Aguilar, Nikolaus Kernich

“…A 1.3% rate of major complications and 1.6% rate of minor complications were recorded as follows: spinal cord damage n = 2 (8.4%), subfaszial hematoma n = 2 (8.4%), motor dysfunction n = 1 (4.2%), cerebrospinal fluid (CSF)-leakage n = 7 (29.2%), sensory dysfunction n = 6 (25%), bowel/bladder dysfunction n = 1 (4.2%), superficial site infection n = 2 (8.4%), and pulmonary lung atelectasis n = 3 (12.5%). …”
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Hierarchizing multi-scale environmental effects on agricultural pest population dynamics: a case study on the annual onset of Bactrocera dorsalis population growth in Senegalese or... by Caumette, Cécile, Diatta, Paterne, Piry, Sylvain, Chapuis, Marie-Pierre, Faye, Emile, Sigrist, Fabio, Martin, Olivier, Papaïx, Julien, Brévault, Thierry, Berthier, Karine

“…Implementing integrated pest management programs to limit agricultural pest damage requires an understanding of the interactions between the environmental variability and population demographic processes. …”
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Determinants of Diabetic Nephropathy among Diabetic Patients in General Public Hospitals of Tigray, Ethiopia, 2018/19 by Teklewoini Mariye Zemicheal, Degena Bahrey Tadesse, Hagos Tasew Atalay, Girmay Teklay Weldesamuel, Gebrewahd Bezabh Gebremichael, Haben Nuguse Tesfay, Teklehaimanot Gereziher Haile

“…Diabetic nephropathy is real damage resulting from having uncontrolled diabetes mellitus. …”
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Self-Assembled Peptide Hydrogels PPI45 and PPI47: Novel Drug Candidates for <i>Staphylococcus aureus</i> Infection Treatment by Quanlong Wu, Mengyin Deng, Ruoyu Mao, Na Yang, Ya Hao, Manli Cao, Da Teng, Jianhua Wang

“…Flow cytometry analysis after 2×MIC peptides treatment for 2 h revealed a 20–38% membrane disruption rate in bacteria, corroborated by scanning electron microscopy (SEM) observations of membrane damage and bacterial collapse. The peptide treatment also led to reduced hyperpolarized membrane potential. …”
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Transformer Outage Contingency in the Southern Interconnected Grid of Cameroon Based on Dynamic Power Flow Simulation by Chu Donatus Iweh, Wirnkar Basil Nsanyuy, Nde Donatus Nguti, Emmanuel Tanyi

“…The power system is a network of components having specific operational limits such that any violation of these limits during their operation could lead to more damage in the grid. The grid in Cameroon has been facing several undesired loading events at some sections of the network and the utility company has over the years, employed measures to mitigate these issues. …”
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Amplifying the Sensitivity of Electrospun Polyvinylidene Fluoride Piezoelectric Sensors Through Electrical Polarization Process for Low-Frequency Applications by Asra Tariq, Amir H. Behravesh, Muhammad Tariq, Ghaus Rizvi

“…Therefore, it is essential to explore methods for polarizing PVDF at the lowest possible voltage to prevent structural damage. In this study, a Design of Experiments (DoE) approach was employed to systematically optimize the polarization parameters using a definitive screening design. …”
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Pulsed Radiofrequency of the Trigeminal Ganglion for Treating Postherpetic Neuralgia of the Ophthalmic Branch by Dong-Yang Liu, Jin-Sheng Chen, Ze-Zang Fang, Shao-Yan Liu, Li Wan

“…Postherpetic neuralgia (PHN) is a painful, long-lasting condition as a consequence of nerve damage resulting from a herpes zoster infection. Although there are many different treatments available to reduce pain duration and severity, PHN is often refractory to them and no single therapy shows an effective cure for all cases of PHN, especially for those involving the ophthalmic branch of the trigeminal nerve. …”
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Moxibustion Regulates the BRG1/Nrf2/HO-1 Pathway by Inhibiting MicroRNA-222-3p to Prevent Oxidative Stress in Intestinal Epithelial Cells in Ulcerative Colitis and Colitis-Associat... by Xuejun Wang, Haiyang Ji, Yanting Yang, Dan Zhang, Xiehe Kong, Xiaoying Li, Hongna Li, Yunqiong Lu, Guang Yang, Jie Liu, Huangan Wu, Jue Hong, Xiaopeng Ma

“…After herb-partitioned moxibustion (HPM) intervention, the disease activity index (DAI) and colon macroscopic damage index (CMDI) were significantly reduced in UC mice, and the number and volume of intestinal tumors were decreased considerably in CAC mice. …”
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LDHA-mediated glycolysis in stria vascularis endothelial cells regulates macrophages function through CX3CL1-CX3CR1 pathway in noise-induced oxidative stress by Ying Yi, Min-Yu Wu, Kai-Tian Chen, An-Hai Chen, Lin-Qiu Li, Qin Xiong, Xian-Ren Wang, Wen-Bin Lei, Guan-Xia Xiong, Shu-Bin Fang

“…Oxidative stress-mediated damage to the stria vascularis (SV) is one of the pathogenic mechanisms of NIHL. …”
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Severe Lipoatrophy in a Growth Hormone Deficient Toddler Girl Treated with a Non-Pegylated Long-Acting Growth Hormone by Atilla Büyükgebiz, And Demir

“…However, lipoatrophy, characterized by irreversible damage to subcutaneous fat, was first reported in 1999 and linked to antibody formation. …”
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Cytological Effects of Serum Isolated from Polytraumatized Patients on Human Bone Marrow-Derived Mesenchymal Stem Cells by Yazhou Long, Katrin Bundkirchen, Pascal Gräff, Christian Krettek, Sandra Noack, Claudia Neunaber

“…However, it is promising to use hBMSCs to treat polytrauma after five days, combined with the concept of “Damage Control Orthopedics” (DCO).…”
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Preimplantation genetic testing for aneuploidy in severe male factor infertility: protocol for a multicenter randomised controlled trial by Li Wang, Li Jin, Yao Lu, Chen Zhang, He-Feng Huang, Yun Sun, Xian-hua Lin, Meng-xi Guo, Dan-dan Wu, Jian-lin Zhang, Cheng-liang Zhou, Chen-ming Xu, Song-chang Chen, Song-ying Zhang, Xiao-xi Sun, Yan-ting Wu

“…However, there are controversies regarding the selection and the damage to gametes during the ICSI procedure. Although preimplantation genetic testing for aneuploidies (PGT-A) can give genetic information about embryos for transfer and improve fertility rate, and it is widely used in women with recurrent spontaneous abortion or advanced age, PGT-A is not only more expensive but also has unclear effectiveness with respect to the improvement of fertility rate among couples with severe male infertility. …”
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Hydrological Behavior of an Infiltration-Induced Landslide in Colorado, USA by Alexandra Wayllace, Barbara Thunder, Ning Lu, Aziz Khan, Jonathan W. Godt

“…When they occur near transportation corridors, they can impact public safety, impede transport of goods and people, and damage transportation infrastructure. This work presents a study of the hydrological behavior and its effects on the stability of an active landslide located on an embankment along Interstate-70 west of the Eisenhower Tunnel in central Colorado, USA. …”
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Changes in Ganglion Cell Complex and Peripapillary Retinal Nerve Fiber Layer after Femtosecond Laser-Assisted Cataract Surgery Compared to Manual Phacoemulsification in Patients Re... by Carmen Sánchez-Sánchez, Laureano A. Rementería-Capelo, Virginia Carrillo, Juan Pérez-Lanzac, Inés Contreras

“…During femtosecond laser-assisted cataract surgery (FLACS), there is a significant increase in intraocular pressure, which might lead to ganglion cell damage. We aimed to determine whether there were differences in the changes produced in the ganglion cell complex (GCC) and peripapillary retinal nerve fiber layer (pRNFL) thickness, as evaluated with optical coherence tomography (OCT), between phacoemulsification and FLACS, after implantation of a trifocal intraocular lens (IOL). …”
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MASFNet: Multi-level attention and spatial sampling fusion network for pine wilt disease trees detection by Dong Ren, Meng Li, Ziyu Hong, Li Liu, Jingfeng Huang, Hang Sun, Shun Ren, Pan Sao, Wenbin Wang, Jingcheng Zhang

“…Pine wilt disease (PWD) is a lethal pest and disease that can result in considerable ecological and economic damage. Using deep learning in combination with unmanned aerial vehicle (UAV) orthophoto remote sensing images to detect PWD trees is an advanced and effective method. …”
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