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12441
Permeability Effect of Green Roof Drainage Board
Published 2023-07-01“…The outputs of this study can be used to manage the flood disasters that may occur in cities due to the increased rainfall intensity due to climate change and to reduce the material and moral damage that may occur. …”
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12442
Augmenter of Liver Regeneration (ALR) Protects Kidney from Ischemia/Reperfusion (I/R) Injury via Regulation of TLR4/MAPK Signaling Pathway
Published 2022-01-01“…In this study, rats induced by renal I/R were treated with recombinant human ALR (rhALR) and demonstrated that the animals were protected from kidney I/R injury, implying that the rhALR-treated rats had less tubular damage than those untreated rats. Meanwhile, tubular epithelial cell apoptosis, neutrophil (24 h) and macrophage (72 h) infiltration to tubulointerstitium, and levels of inflammatory cytokines were decreased considerably in the rhALR-treated rats as compared to control. …”
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12443
Spatial-Temporal Analysis of Crash Severity: Multisource Data Fusion Approach
Published 2022-01-01“…Fatalities, injuries, and medical costs, as well as road and car damage and mental side effects, are more important consequences of severe crashes. …”
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12444
Clinical Characteristics and Prognostic Factors of Posterior Segment Intraocular Foreign Body: Canadian Experience from a Tertiary University Hospital in Quebec
Published 2021-01-01“…Predictive factors for poor VA outcome included poor baseline VA, larger IOFB size, high number of additional diagnoses, an anterior chamber extraction, a second intervention, the use of C3F8 or silicone tamponade, and the presence of vitreous hemorrhage, hyphema, and iris damage. Predictive factors for a better visual outcome included first intention intraocular lens (IOL) implantation and the use of air tamponade. …”
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12445
Management of acute bacterial meningitis in a limited resource setting: an Egyptian consensus model
Published 2025-01-01“…Those who do recover, especially if there was delayed appropriate intervention, can have permanent disabilities, such as brain damage, hearing loss, and learning disabilities. Rapid intervention in such cases is mandatory, which is not easy in countries with limited income due to weak capabilities and resources. …”
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12446
Effect of Locally Delivered Melatonin as an Adjunct to Nonsurgical Therapy on GCF Antioxidant Capacity and MMP-9 in Stage II Periodontitis Patients: A Randomized Controlled Clinica...
Published 2021-01-01“…The increase in reactive oxygen species (ROS) is responsible for the oxidative damage occurring in periodontal tissues. Melatonin has important immunomodulatory, anti-inflammatory, and powerful antioxidant functions. …”
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12447
Our Surgical Results in Popliteal and Infrapopliteal Artery Injuries: 21 Cases without Amputation
Published 2024-01-01“…No patient developed amputation. Foot drop developed with nerve damage in 2 patients. Conclusion. …”
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12448
Multi-pathway oxidative stress amplification via controllably targeted nanomaterials for photoimmunotherapy of tumors
Published 2025-01-01“…This multi-pathway oxidative stress amplification and photothermal effect can trigger immunogenic cell death in tumors, promoting the release of relevant antigens and damage-associated molecular patterns, thereby increasing dendritic cell maturation and sensitivity of tumor cells to immunotherapy. …”
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12449
Hydroxyurea mitigates diabetic kidney disease through mTOR-S6K signaling pathway in STZ-induced diabetic mice
Published 2025-01-01“…Lastly, the mTOR-S6K pathway was explored by detecting the protein expression of S6K and phosphorylated S6K.ResultsIn STZ-induced diabetic mice, administration of HU (20 mg/kg) in drinking water for 16 weeks resulted in significant reductions in creatinine and urea nitrogen levels, alongside mitigating histopathological damage. Additionally, HU effectively suppressed the inflammatory response and apoptosis within the kidneys. …”
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12450
Serum Levels of Mitochondrial Fission- and Fusion-Related Genes of Coal Workers’ Pneumoconiosis and Risk Factor Analysis Based on a Generalized Linear Model
Published 2022-01-01“…With the aggravation of CWP, the degree of fibrosis and inflammation increased oxidative damage, increased mitochondrion division, and decreased fusion, which were more sensitive in the second and third stages of CWP. …”
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12451
Combination of ataxia telangiectasia and Rad3-related inhibition with ablative radiotherapy remodels the tumor microenvironment and enhances immunotherapy response in lung cancer
Published 2024-11-01“…ATR inhibition enhanced radiation-induced damage-associated molecular patterns determined by high mobility group box 1 quantification and activated the cyclic GMP-AMP synthase-stimulator of interferon genes pathway. …”
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12452
Design of a Combined Solar Powered Pasture Chopping and Conveying Machine.
Published 2023“…Zero grazing provides advantages like Animals are kept inside hence more secure, feeds are utilized well, reduces pasture damage, maximum use of land, urban and peri-urban farmers can keep cattle, many animals can be fed from a small area, easy collection of manure, crop and biogas production, and easy detection of heat in animals. [1]. …”
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12453
Effect of High Alcohol Consumption Among the Youth in Kitumba Sub County-Kabale District.
Published 2024“…The effects of alcohol consumption on the youths according to the study findings were; school dropout, increased thefts, loss of jobs, committing suicide, wastage of money, increased stress, poor coordination, slurred speech, destruction of the reproductive system, damage of; the brain, liver, kidney, and breast, contraction of HIV, and death. …”
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12454
Tecnopolítica, participación electrónica y comunicación digital
Published 2021-03-01“…• Nombre del doctorando: D.ª Dafne Calvo Miguel • Universidad: Universidad de Valladolid • Fecha de lectura: 13/10/2020 • Dirección: D.ª Eva María Campos Domínguez Las características de Internet como un espacio abierto y descentralizado despertaron en sus pri- meros años la esperanza de una mayor autonomía y libertad de la ciudadanía ciberconectada. …”
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12455
FTO rs17817449 Variant Increases the Risk of Severe Obesity in a Brazilian Cohort: A Case-Control Study
Published 2025-01-01“…Kaio Cezar Rodrigues Salum,1,2 Izadora Sthephanie da Silva Assis,1,2 Úrsula de Almeida Kopke,3 Lohanna Palhinha,4 Gabriella de Medeiros Abreu,2,5 Laura Wendling Gouvêa,1,2 Myrela Ribeiro Teixeira,2,6,7 Fernanda Cristina C Mattos,5 José Firmino Nogueira Neto,8 Rafaela de Freitas Martins Felício,9,10 Eliane Lopes Rosado,5 Verônica Marques Zembrzuski,2 Mario Campos Junior,2 Clarissa Menezes Maya-Monteiro,4 Pedro Hernán Cabello,2 João Regis Ivar Carneiro,1 Patrícia Torres Bozza,4 Fabiana Barzotto Kohlrausch,6 Ana Carolina Proença da Fonseca2,4,11 1Medical Clinic Department, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil; 2Human Genetics Laboratory, Oswaldo Cruz Institute, Rio de Janeiro, Brazil; 3Chester Medical School, University of Chester, Chester, UK; 4Laboratory of Immunopharmacology, Oswaldo Cruz Institute, Rio de Janeiro, Brazil; 5Institute of Nutrition Josué de Castro, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil; 6Human Genetics Laboratory, Institute of Biology, Federal Fluminense University Niterói, Rio de Janeiro, Brazil; 7Postgraduate in Sciences and Biotechnology, Fluminense Federal University Niterói, Rio de Janeiro, Brazil; 8Department of Pathology and Laboratory, Rio de Janeiro State University, Rio de Janeiro, Brazil; 9Birth Defect Epidemiology laboratory, Oswaldo Cruz Institute, Rio de Janeiro, Brazil; 10Health Care Network for Congenital Anomalies of the Central Nervous System, Instituto Oswaldo Cruz, Rio de Janeiro, Brazil; 11Genetics Laboratory, Grande Rio University, Rio de Janeiro, BrazilCorrespondence: Ana Carolina Proença da Fonseca, Laboratory of Immunopharmacology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation (Fiocruz), 4365 Brasil Avenue, 108 Building – Office 44, Rio de Janeiro, 21040-360, Brazil, Tel +55(21)38658192, Email ana.proenca@ioc.fiocruz.br Kaio Cezar Rodrigues Salum, Human Genetics Laboratory, Oswaldo Cruz Institute, Oswaldo Cruz Foundation (Fiocruz), 4365 Brasil Avenue, Leônidas Deane Building – Office 611/615, Rio de Janeiro, 21040-360, Brazil, Tel +55 21 38658213, Fax +55 21 38658239, Email kaio.salum@hotmail.comPurpose: Obesity is a complex disease caused by a combination of genetic, environmental, and epigenetic factors, and is associated with an increased risk of chronic diseases. …”
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12456
PhotoD with LSST: Stellar Photometric Distances Out to the Edge of the Galaxy
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Fu Tu Sheng Jin Rehabilitation Formula Mitigate Airway Inflammation, Mucus Secretion and Immune Dysfunction Induced by SARS-CoV-2 Spike Protein
Published 2025-01-01“…The D10 group of mice displayed increased levels of IL-4, TNF-α, IL-33 and mucin genes such as MUC1, MUC4, etc, and FTSJRF inhibited the expression of these molecules, mucus secretion and lung damage in SARS-CoV-2 spike protein-induced mouse model. …”
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12460
Surfactin alleviated hyperglycaemia in mice with type 2 diabetes induced by a high-fat diet and streptozotocin
Published 2023-11-01“…Bioactive peptides (BAPs) have been reported to ameliorate T2DM by preventing oxidative damage to the liver. Bacillus amyloliquefaciens fmb50 produces the lipopeptide surfactin with a wide range of biological activities. …”
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