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12361
Sex-based disparities in the association between uric acid levels and anxiety: a cross-sectional analysis of nationwide data in Korea
Published 2025-01-01“…Despite reports of increased oxidative damage and decreased antioxidants in anxiety disorders, findings remain inconclusive. …”
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12362
The periplasmic protein HslJ is the first-line of defense against oxidative stress in Acinetobacter baumannii
Published 2025-01-01“…In this study, we demonstrate the pivotal function of HslJ as the first line of defense against oxidative damage induced by hydrogen peroxide (H2O2). Methods An isogenic site-specific hslJ mutant of A. baumannii AB5075 was used to evaluate its sensitivity to H2O2, survival rate in human macrophages, biofilm, cell surface hydrophobicity, and motility. …”
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12363
Extensive In Silico Analysis of ATL1 Gene : Discovered Five Mutations That May Cause Hereditary Spastic Paraplegia Type 3A
Published 2020-01-01“…The aim of this work was to categorize the most damaging SNPs in ATL1 gene and to predict their impact on the functional and structural levels by several computational analysis tools. …”
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12364
Dynamic 19F-MRI of pulmonary ventilation in lung transplant recipients with and without chronic lung allograft dysfunction
Published 2025-02-01“…Background: By the time chronic lung allograft dysfunction (CLAD), with its main phenotypes bronchiolitis obliterans syndrome (BOS) and restrictive allograft syndrome (RAS), is diagnosed by pulmonary function testing, irreversible damage to the lung allograft may already have occurred. …”
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12365
Hypericin-Mediated Photodynamic Therapy for Head and Neck Cancers: A Systematic Review
Published 2025-01-01“…Photodynamic therapy (PDT) has emerged as a promising alternative, leveraging photosensitizers such as hypericin to selectively target tumour cells with minimal damage to surrounding healthy tissues. <b>Objectives</b>: We aimed to evaluate the efficacy and underlying mechanisms of hypericin-mediated PDT (HY-PDT) in treating head and neck cancers. …”
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12366
Extracellular CIRP Upregulates Proinflammatory Cytokine Expression via the NF-kappaB and ERK1/2 Signaling Pathways in Psoriatic Keratinocytes
Published 2022-01-01“…C23, a short peptide derived from CIRP, competitively binds CIRP receptors and reduces damage in inflammatory diseases. However, the effect of eCIRP in psoriasis has not been studied. …”
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12367
Effect of nanocurcumin (Curcuma longa) on lung histopathology in rats exposed to carbon black
Published 2025-01-01“…Conclusion Nanocurcumin administration demonstrates potential in mitigating alveolar septal thickening and fibrosis in rat lungs subjected to carbon black exposure, suggesting a protective role against pulmonary damage from particulate matter. …”
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12368
Clinical Evaluation of Acute Pancreatitis Caused by SARS-CoV-2 Virus Infection
Published 2021-01-01“…The rate of pancreatic damage in SARS-CoV-2 infection was found to be 19% (n=29) in our study. …”
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12369
Assessment of 8-hydroxy-2-deoxyguanosine activity, apoptosis, acetylcholinesterase and antioxidant enzyme activity in Capoeta umbla brain exposed to chlorpyrifos
Published 2022-06-01“…The obtained data indicate a significant increase in the MDA level and inhibition of antioxidant enzymes in the brain (p < 0.05). Considering DNA damage and the apoptotic process, no significant changes were found in 8-OHdG and caspase-3 activity at both doses exposed for 24 h, but a significant increase was detected in both markers at 96 hours compared to the control group (p < 0.05). …”
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12370
Disastrous Mechanism of Water Discharge in Abandoned Gob above the Stope in Mining Extra-Thick Coal Seam
Published 2021-01-01“…With the exploitation of the 3-5# extra-thick coal seam in the Carboniferous system, the scope of overburden damage is greatly increasing, and the mining fracture field is further developed. …”
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12371
Usp11 maintained the survival of marginal zone B cells under ionizing radiation by deubiquitinating DLL1 and JAG2
Published 2025-02-01“…In conclusion, Usp11 played a crucial role in modulating immune system damage induced by ionizing radiation, primarily through ubiquitination of Notch ligands. …”
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12372
Using the fuzzy cognitive map in designing a decision support system in diabetes insipidus
Published 2024-11-01“…But with a faster and timely diagnosis, it can be prevented from progressing and the damage of lack of treatment, which can be irreparable. …”
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12373
Influence of Wheel Profile Wear Coupled with Wheel Diameter Difference on the Dynamic Performance of Subway Vehicles
Published 2021-01-01“…Later, the interaction between the effects of WPW and equivalent in-phase WDD on the vehicle dynamic performance was analyzed, and the dynamic response in the presence of coupled damage was compared between the outer and inner wheels. …”
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12374
Strengthening Russia’s International Prestige during the Northern War: Russian Diplomatic Institutions and Instruments
Published 2022-05-01“…To limit the dissemination of information damaging Russia’s prestige, Russian diplomats began to use the same instruments of influence (newspapers, magazines, and pamphlets), which European diplomats used at that time: various methods of pressure and bribery, propaganda, and censorship. …”
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12375
Suitability Analysis of Three Quick-Freezing Techniques for Application in Bamboo Shoot Freezing
Published 2024-12-01“…In addition, the structure of vascular bundles was seriously damaged by PSF, resulting in 6.12%-10.47% thawing loss and more serious water migration. …”
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12376
Ishophloroglucin A Isolated from <i>Ishige okamurae</i> Protects Glomerular Cells from Methylglyoxal-Induced Diacarbonyl Stress and Inhibits the Pathogenesis of Diabetic Nephropath...
Published 2025-01-01“…IPA protected cells from MGO-induced oxidative stress by inhibiting intracellular MGO accumulation (untreated cells: 1.62 μg/mL, MGO treated cells: 25.27 μg/mL, and IPA 5 μM: 11.23 μg/mL) (<i>p</i> < 0.001) and AGE generation and inhibited MGO-induced renal cell damage via the downregulation of MGO-induced RAGE protein expression (relative protein expression levels of MGO treated cells: 9.37 and IPA 5 μM:1.74) (<i>p</i> < 0.001). …”
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12377
INONDATIONS TORRENTIELLES EN ZONES MONTAGNEUSES AFFÉRENTES AU GOLFE DU MEXIQUE
Published 2009-12-01“…The consequences of these devastating floods were many casualties andmaterial damage over large areas. After a time, erosion processes become more numerous with disastrous soil loss, particularly in mountainous areas (slopes), moreover so, if used for farming or grazing. …”
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12378
The N‐terminal domain of gasdermin D induces liver fibrosis by reprogrammed lipid metabolism
Published 2025-01-01“…Results Doxycycline‐treated GSDMD‐NTki/wt × Alb‐creki/wt mice showed severe liver damage, vacuolation of hepatocytes, increased collagen fibers, and accumulation of lipid droplets. …”
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12379
High Frequency Vibration Fatigue Behavior of Ti6Al4V Fabricated by Wire-Fed Electron Beam Additive Manufacturing Technology
Published 2020-01-01“…Following foreign object damage (FOD), a decision to repair components using novel additive manufacturing (AM) technologies has good potential to enable cost-effective and efficient solutions for aircraft gas turbine engine maintenance. …”
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12380
Role of cytokines in myocardial ischemia and reperfusion
Published 1997-01-01“…At the cellular level it has been shown that hypoxia causes a series of well documented changes in cardiomyocytes that includes loss of contractility, changes in lipid metabolism and subsequent irreversible cell membrane damage leading to cell death. For instance, hypoxic cardiomyocytes produce interleukin-6 (IL-6) which could contribute to the myocardial dysfunction observed in ischemia reperfusion injury. …”
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