piR-26441 inhibits mitochondrial oxidative phosphorylation and tumorigenesis in ovarian cancer through m6A modification by interacting with YTHDC1 by Jing Yuan, Bu-Min Xie, Yu-Meng Ji, Hai-Juan Bao, Jie-Lin Wang, Jia-Chen Cheng, Xiang-Chun Huang, Yang Zhao, Shuo Chen

“…The resultant TSFM loss reduced mitochondrial complex I activity and mitochondrial OXPHOS, leading to mitochondrial dysfunction in OC cells, increased reactive oxygen species levels, and thus, DNA damage and apoptosis in OC cells, thereby inhibiting OC progression. …”
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Complications and Mortality Characterization in Acute Ischemic Cerebrovascular Disease by Ricardo Leyva Tornés, Lázaro Ibrahim Romero García, Esther Mayor Guerra, Yordanis Páez Candelaria, Karima Gondres Legró, Pedro Alexei Bacardí Zapata

“…<br /><strong>Objective:</strong> to describe the most frequent complications incidence in the patients suffering from cerebrovascular disease population, as well as the burden of mortality associated with this neurological damage. <br /><strong>Method:</strong> a descriptive study was carried out in patients with ischemic cerebrovascular disease who leaved from the Neurology Service of the Saturnino Lora Torres Provincial Clinical Surgical Teaching Hospital in the 2017-2019 triennium. …”
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The First Report of Tomato Yellow Leaf Curl Virus (TYLCV) Occurrence in Tomato Greenhouses of Lorestan Province by Farzaneh Rostami, Samira Pakbaz, Mostafa Darvishnia

“…Tomato yellow leaf curl virus (TYLCV) is one of the most important tomatoes (Solanum lycopersicum L.) viral diseases in tropical, subtropical, and temperate regions of the world. The amount of damage caused by this virus is severe and may reach 100%. …”
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Relations on Ensuring the Rights and Freedoms of a Man and Citizen as a Component of the Subject Matter of Administrative Law by A. T. Komziuk, Ye. A. Lypii

“…However, it is no less important to maintain proper public order and security, to counteract to various illegal manifestations that infringe on these rights and freedoms, causing some damage, sometimes quite significant. The conclusion is made about the expediency of taking into account the relations concerning the provision of human rights and freedoms and its elements, in particular protection and defense in the construction of the system of administrative law.…”
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Functional Connectivity and MRI Radiomics Biomarkers of Cognitive and Brain Reserve in Post-Stroke Cognitive Impairment Prediction—A Study Protocol by Hanna Maria Dragoș, Adina Stan, Livia Livinț Popa, Roxana Pintican, Diana Feier, Nicu Cătălin Drăghici, Dragoș-Cătălin Jianu, Diana Chira, Ștefan Strilciuc, Dafin F. Mureșanu

“…Brain reserve refers to the brain’s structural capacity to compensate for damage, with markers like hippocampal atrophy and white matter lesions indicating reduced reserve. …”
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Cystatin C Levels in Middle-Aged Patients with Obstructive Sleep Apnea Syndrome by Kostas Archontogeorgis, Evangelia Nena, Christina Tsigalou, Athanasios Voulgaris, Maria Xanthoudaki, Marios Froudarakis, Paschalis Steiropoulos

“…Cystatin C (Cyst C) is a novel biomarker of both latent renal damage and cardiovascular disease. Aim of the study was to measure serum levels of Cyst C, as well as IL-8 and CRP, in otherwise healthy OSAS patients. …”
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Selective laser trabeculoplasty for the treatment of intraocular pressure elevation after viscocanalostomy with Ologen implant in the management of primary open-angle glaucoma: a r... by Ahmed AM Gad, Bahaa-Eldin Hasan Abdulhalim, Amal F Gharib, Amr Mahfouz Mohammed

“…These eyes showed a progression of glaucomatous damage, the IOP was above 21 mmHg, or with intolerable glaucoma medications. …”
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Profiles of systemic lupus erythematosus patients with co-existing sickle cell disease: a coincidence or true association? by Hakeem Babatunde Olaosebikan, Etseoghena Igebu, Adebukola Khairat Orolu, Gbenga Joshua Odunlami, Ilo Azizat Bamisebi, Akin Dada, Ebele Uche, Olufemi Adelowo

“…We hope this report will raise diagnostic suspicion and prompt early diagnosis and treatment to prevent multiorgan damage that may ensue from such an association.…”
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Evaluation of the Anthropogenic Impacts of Yusufeli Dam in terms of Landscape Planning by Belgin Yılmam, Hilal Turgut

“…This study aims to determine the anthropogenic pressures in the construction and production processes of the Yusufeli Dam. Kılıçkaya, Öğdem, and Yusufeli regions were chosen as the study area because they were affected by the Yusufeli Dam. …”
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Clinical Practice Guidelines of the Scientific Society for the Clinical Study of Human Microbiome, of the Russian Gastroenterological Association and the Russian Society for the Pr... by V. T. Ivashkin, O. S. Lyashenko, O. M. Drapkina, O. P. Alexeeva, S. A. Alekseenko, D. N. Andreev, A. Yu. Baranovsky, O. V. Goloshchapov, N. V. Zheleznova, O. Yu. Zolnikova, I. L. Kliaritskaia, N. V. Korochanskaya, T. L. Lapina, I. V. Maev, R. V. Maslennikov, R. G. Myazin, P. V. Pavlov, M. V. Perekalina, N. A. Pisarenko, A. V. Povtoreyko, E. A. Poluektova, L. A. Sekretareva, A. V. Tkachev, Yu. M. Troshkina, A. S. Trukhmanov, A. I. Ulyanin, S. G. Filatova, V. V. Tsukanov, O. S. Shifrin

“…C. difficile-associated disease is a disease that develops when the diversity of the intestinal microbiota decreases and C. difficile excessively colonizes the colon, the toxins of which damage the intestinal muco-epithelial barrier, followed by the development of inflammation in the colon wall, with diarrhea being a characteristic clinical manifestation. …”
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Metagenomic analysis of goat feces from Ogliastra (Sardinia, Italy) by Monica Rosaria Molotzu, Piera Angela Cabras, Lisa Di Marcantonio, Rossano Atzeni, Nicolò Pietro Paolo Macciotta, Antonella Canu

“…We also evaluated possible differences in the composition of the intestinal microbiota between healthy and Caprine arthritis encephalitis (CAE)-affected goats. The economic damage caused by this pathology is due to the reduction in milk production, with infected animals having greater susceptibility to contract diseases. …”
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Assessing the impact of climate and land use change on flood vulnerability: a machine learning approach in coastal region of Tamil Nadu, India by Devanantham Abijith, Subbarayan Saravanan, K S S Parthasarathy, Nagireddy Masthan Reddy, Janardhanam Niraimathi, Ahmed Ali Bindajam, Javed Mallick, Maged Muteb Alharbi, Hazem Ghassan Abdo

“…They can cause significant damage to infrastructure and disrupt economies. Tamil Nadu coast is severely prone to flooding due to land use and climate changes. …”
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Resistance of European plum to fungal diseases in the foothill zone of Adygea by V. V. Sherstobitov, M. A. Kolesova

“…Weather and climate conditions during the flowering, fruit growth and ripening periods of European plum affected the degree of damage inflicted by fungal diseases. Many years of testing resulted in identifying P. domestica cultivars with different scores of resistance to brown rot, shot hole, and rust. …”
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Numerical Modeling of Reactive Transport and Self-Sealing Processes in the Fault-Controlled Geothermal System of the Guide Basin, China by Zhaoyun Hou, Tianfu Xu, Guanhong Feng, Bo Feng, Yilong Yuan, Zhenjiao Jiang

“…The modeling domain was discretized based on multiple interacting continua (MINC) approach, to address the nonequilibrium heat transport processes between the matrix and conduit in the fractured fault damage zone. Once the model was validated by observations of major ions in spring water and downhole temperature logs in the discharge area, it was used to determine the coupled processes of fluid, heat, and chemical transport in the reservoir and the resultant sealing ranges. …”
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Genome-wide CRISPR-based screen identifies E2F transcription factor 1 as a regulator and therapeutic target of aristolochic acid-induced nephrotoxicity by Ziqi Liu, Huan Gao, Guoliang Li, Yongjiang Yu, Mengxing Cui, Honghao Peng, Xinchao Guan, Xue Zhang, Zhihan Zhang, Xiaoyu Shen, Shen Chen, Daochuan Li, Liping Chen, Yongmei Xiao, Wen Chen, Lili Liu, Qing Wang

“…Aristolochic Acid I (AAI) is widely present in traditional Chinese medicines derived from the Aristolochia genus and is known to cause significant damage to renal tubular epithelial cells. Genome-wide screening has proven to be a powerful tool in identifying critical genes associated with the toxicity of exogenous substances. …”
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The effects of postpartum routine intrauterin treatments on fertility in cows by Yunus Çetin, Örsan Güngör, İbrahim Taşal, Cevat Sipahi, Sait Şendağ, Mehmet Yıldız, Axel Wehrend

“…In addition, the use of high irritation chemicals in this period propably may cause damage to the healthy endometrial tissue, leading to a decrease in fertility rates.…”
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Vitronectin regulates focal adhesion turnover and migration of human placenta-derived MSCs under nutrient stress by Srishti Dutta Gupta, Nitish Pal, Malancha Ta

“…At sites of tissue damage and wound healing, the mesenchymal stem cells (MSCs) are often challenged by nutrient availability due to blood supply disruption. …”
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Effectiveness of post-harvest treatments for Manzanilla table olives and the suitability of Hojiblanca as a substitute for mechanical harvesting by Paz Shemesh, Arnon Dag, Nizar Abd Elhadi, Reza Ehsani, Louise Ferguson, Ayelet Fishman

“…Hojiblanca and Picual olives were more robust during mechanical harvesting with a trunk shaker or electrical comb, however, using an overhead harvester severely damaged even the relatively resistant cultivars. Sensory evaluation through a paired-comparison test and ranking tests indicated no significant preference difference between Hojiblanca and Manzanilla (p < 0.05), supporting Hojiblanca's potential as a substitute for Manzanilla in table olive production. …”
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The “Nixon China Shock” in the Mirror of Japanese Domestic Politics by V. V. Nelidov

“…It proves that these factors were one of the reasons for Japan’s political leadership avoiding decisive actions to normalize relations with the PRC before the “Nixon shock”, cautious that it might damage its relations with the U.S. and unable to discern the signs of upcoming U.S.…”
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Pharmacological Effects of Antioxidant Mycosporine-Glycine in Alleviating Ultraviolet B-Induced Skin Photodamage: Insights from Metabolomic and Transcriptomic Analyses by Kai Wang, Ling Qin, Huan Lin, Mengke Yao, Junhan Cao, Qing Zhang, Changfeng Qu, Yingying He, Jinlai Miao, Ming Liu

“…These findings highlight M-Gly’s potential as an endogenous antioxidant for protecting skin from UVB-induced damage.…”
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