The Fungi-specific histone Acetyltransferase Rtt109 mediates morphogenesis, Aflatoxin synthesis and pathogenicity in Aspergillus flavus by acetylating H3K9 by Ruilin Sun, Meifang Wen, Lianghuan Wu, Huahui Lan, Jun Yuan, Shihua Wang

“…The amount of aflatoxins synthesized by △rtt109 in the PDB liquid medium was significantly decreased We also found that the △rtt109 strain was extremely sensitive to DNA damage stress. Through the maize seed infection experiment, we found that the growth of △rtt109 on the surface of affected corn was largely reduced, and the amount of aerial mycelium decreased significantly, which was consistent with the results on the artificial medium. …”
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Biomarkers of Oxidative Stress in Huntington's Disease and Other Neurological Disorders: a Comparative Study by Marisol Peña Sánchez, Gabriel Andrés Peña de los Santos, Gretel Riverón Forment, Gloria Lara Fernández, Tatiana Acosta Sánchez, Alina González-Quevedo Monteagudo

“…Demographic and clinical variables and markers of oxidative damage (malonildialdehyde, advanced protein oxidation products) and antioxidants (superoxide dismutase: catalase: glutathione peroxidase, plasma antioxidant capacity) were collected. …”
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Penyelesaian Kasus Kecelakaan Lalu Lintas Yang Menimbulkan Luka Berat Berdasarkan Keadilan Restoratif by Irvan, Susi Delmiati, Amiruddin

“…Meskipun tergolong kecelakaan berat, namun peristiwa kecelakaan tersebut berhasil diselesaikan secara damai dengan melibatkan peran penyidik Satlantas Polres Padang Panjang. …”
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Experimental Study and Life Prediction of Bolt Loosening Life under Variable Amplitude Vibration by Guangwu Yang, Chengjian Che, Shoune Xiao, Bing Yang, Tao Zhu, Shilin Jiang

“…Linear accumulation of bolt loosening is with similar principle of linear damage accumulation of material fatigue. Therefore, the bolt loosening life can be predicted through bolt displacement-loosening life (D-N) curve attained from the experiment and the established linear accumulation model of bolt loosening.…”
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Obesity and Cytokines in Childhood-Onset Systemic Lupus Erythematosus by Nailú Angélica Sinicato, Mariana Postal, Fernando Augusto Peres, Karina de Oliveira Peliçari, Roberto Marini, Allan de Oliveira dos Santos, Celso Dario Ramos, Simone Appenzeller

“…cSLE patients were assessed for disease and damage. Obesity was definite as body mass index (BMI) ≥30 kg/m2. …”
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Study on Crack Evolution and Failure Mechanism of Fully Penetrated Fracture Grouting Body by Hanqing Wang, Li Li, Xinwang Li, Lichao Cheng, Pengfei Shen

“…Comparisons of the crack inclination in slurry specimens under different loading rates imply that there is a critical value of crack inclination at 45° which concentrates the damage and cracking of the grouted body under compression within the grouted solidified body. …”
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Shallow tunneling's impact on surface settlements by Mohamed Djenane, Kamel Bezih

“…The study focuses on carrying out a numerical analysis and a parametric geotechnical study to investigate the effects of tunnel excavation on the surface ground, particularly with regard to distortion and potential damage to structures above the tunnel. To carry out the study, the researcher used a finite element method (FEM) software package called Plaxis. …”
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Dioscin pretreatment ameliorates ferroptosis in cardiomyocytes after myocardial infarction via inhibiting endoplasmic reticulum stress by Chang Wu, Xueping Shen, Pan Lou, Dongyan Song

“…Abstract Background Myocardial infarction (MI) remains a leading cause of mortality globally, often resulting in irreversible damage to cardiomyocytes. Ferroptosis, a recently identified form of regulated cell death driven by iron-dependent lipid peroxidation, has emerged as a significant contributor to post-MI cardiac injury. …”
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Effect of Homogenization Process on the Production of Arthrospira platensis Carotenoid Nanocapsules Encapsulated with Arabic Gum and Whey Protein Concentrate by Khusnul Alfionita, Siti Ari Budhiyanti, Nurfitri Ekantari

“…Therefore, efforts were needed to protect carotenoids from damage by using an encapsulation system. The emulsion preparation before the encapsulation process had an influence on the stability of the oil-in-water emulsion. …”
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A Novel “Slit Side View” Method to Evaluate Fluid Dynamics during Phacoemulsification by Hisaharu Suzuki, Tsutomu Igarashi, Toshihiko Shiwa, Hiroshi Takahashi

“…However, the corneal endothelium can be damaged during phacoemulsification by multiple factors. …”
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Development of Deep Intelligence for Automatic River Detection (RivDet) by Sejeong Lee, Yejin Kong, Taesam Lee

“…Additionally, the RivDet artificial intelligence model for automatic river path configuration developed in the current study is expected to solve various problems, such as automatic flow rate estimation for river disaster prevention, setting early flood warnings, and calculating the range of flood inundation damage.…”
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Numerical Simulation of Acoustic Emission Events in Supporting Roadways under Different Dynamic Loads by Wenzheng Shang, Zhigang Liu, Jianbo Yuan, Wuchao You, Shuai Han, Lei Yu, Shihua Zhang

“…According to the model dynamic load application criterion, the relationship between the peak velocity of the particle, the distance from the source center to the dynamic impact damage point, and the dynamic load intensity is introduced. …”
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Effects of Chronic Stress and Comfort Food in Testicular Morphology in Adult Wistar Rats by Carina F. Barnabé, Roger G. Marchon, Maria V. C. Pinto, Bianca M. Gregório, Anneliese Fortuna-Costa, Francisco J. B. Sampaio, Diogo B. De Souza

“…While comfort food also reduced the epithelium in C+CF in comparison to controls, for group S+CF the comfort food ameliorated the stress-induced damage. The cell proliferation rate and the relative expression of StAR and BLC2 genes were similar between the groups. …”
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Epidemiological and Clinical Profile of Dermatoses Observed in Chronic Hemodialysis Patients at the National Teaching Hospital (NTH-HKM) of Cotonou, Benin by Hugues Adégbidi, Fabrice Akpadjan, Odile Houngbo, Jacques Vigan, Bérénice Dégboé, Nadège Agbessi, Christiane Koudoukpo, Félix Atadokpèdé

“…Introduction. Dermatological damage in chronic hemodialysis patients is not uncommon. …”
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Investigation of factors that affect post-fire recovery of photosynthetic activity at global scale by Yicheng Shen, I. Colin Prentice, Sandy P. Harrison

“…Fire properties which indicate substantial vegetation damage, such as fire intensity and duration, result in longer recovery times. …”
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Simulation and Analysis of the Optimal Electric Field from Modifications to the Winding Design for the Tesla Transformer by Nattachote Rugthaicharoencheep, Supawud Nedphokaew

“…The winding that has space is dielectric; while there is high voltage in a transformer, it causes flashover voltage between the high-voltage winding and low-voltage winding, which damages the transformer and other devices. Research process: Research was conducted to study the laydown model (positioning) of the two windings in the transformer. …”
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Development of Collagen-Based 3D Matrix for Gastrointestinal Tract-Derived Organoid Culture by Joo Hyun Jee, Dong Hyeon Lee, Jisu Ko, Soojung Hahn, Sang Yun Jeong, Han Kyung Kim, Enoch Park, Seon Young Choi, Sukin Jeong, Joong Woon Lee, Han-Jun Cho, Min-Soo Kwon, Jongman Yoo

“…When mouse colon organoids were transplanted with collagen matrix into the EDTA-colitis mouse model, colon organoids were successfully engrafted in damaged tissue. For that reason, the use of collagen-based matrix in organoid culture will render organoid cultivation less expensive and clinically applicable.…”
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Mesenchymal stem cell-derived extracellular vesicles enriched with miR-124 exhibit anti-inflammatory effects in collagen-induced arthritis by Guo Zhonghua, He Mengyuan, Shi Dongliang, Zhang Zhongbo, Wang Lisha, Ren Bowen, Wang Yunfei, Wang Junjie, Yang Shaoxiang, Yu Hongchao

“…Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by joint inflammation, leading to pain, swelling, stiffness, and joint damage. Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) hold significant promise as therapeutic agents owing to their potent paracrine activities. …”
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Ecological network construction and optimization of typical resource-based regions, and strategies for the enhancement of multiple ecosystem services: Balancing function and struct... by Shaoqing Wang, Yanling Zhao, Qiyuan Wang, He Ren, Shichao Zhu, Jiarui Cao

“…This study also examined the ecological and topological characteristics of ecological sources with or without mining areas (damaged ecological sources (DESs) and basic ecological sources (BESs)). …”
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Magnolol induces cell death through PI3K/Akt‐mediated epigenetic modifications boosting treatment of BRAF‐ and NRAS‐mutant melanoma by Abdullah Al Emran, Brinda Reddy Chinna Chowdary, Farzana Ahmed, Heinz Hammerlindl, Antje Huefner, Nikolas K. Haass, Wolfgang Schuehly, Helmut Schaider

“…Alongside, the repressive histone mark H3K9me3 was increased as a response to DNA damage. Magnolol‐induced alterations of histone modifications are reversible upon activation of the Akt pathway. …”
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