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11621
Investigation of morphology changes in Karun River and its hazards (Case Study: Bandagir to Khorramshahr)
Published 2023-03-01“…These changes have resulted in the destruction of natural habitats along the river, the ability to self-purify water, sudden floods, threatening and damaging human structures, agriculture, and so on.…”
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11622
Baicalin: a potential therapeutic agent for acute kidney injury and renal fibrosis
Published 2025-01-01“…Renal fibrosis, defined as the excessive accumulation of collagen and proliferation of fibroblasts within renal tissues, contributes to the structural damage and functional decline of the kidneys, playing a pivotal role in the advancement of Chronic Kidney Disease (CKD). …”
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11623
Video Spectral Methods and Tools for Monitoring of Controlled Parameters of Forest Fires and Oil Spill Accidents
Published 2023-04-01“…Its purpose, composition and main technical parameters were indicated.Spectral-polarization studies of the characteristics of samples that simulates objects (pollution) of natural (forest fires) and man-made (oil spills) emergencies were performed with the help of complex “Vizir” using polarizing nozzles under various conditions (angles of illumination, observation, pollution concentration, the time that passed since the contamination, the degree of wood thermal damage). The results of studies made it possible to increase the accuracy of identification of monitoring objects in emergency zones up to two times.The main provisions of the two developed methods were outlined. …”
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11624
CDK14 regulates the development and repair of lung
Published 2025-01-01“…Genetic knockout of Cdk14 and the CDK14 covalent inhibitor FMF-04-159-2 resulted in reduction of pulmonary vessel covered area and epithelial cell number, exhibiting increased mortality and more severe lung damage after injury. Mechanistically, Cdk14 ablation inhibited the proliferation of epithelial and vascular endothelial cells, inducing cell cycle arrest at the G2/M phase. …”
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11625
Challenges, dilemmas and success criteria of recycling coal mining landscapes
Published 2024-12-01“…As our crowded and warming world continues moving away from fossil fuels such as coal, we are increasingly attempting to transform the landscapes damaged by mining into beneficial, appealing and valuable new uses. …”
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11626
Treatment of Radiation Bone Injury with Transplanted hUCB-MSCs via Wnt/β-Catenin
Published 2021-01-01“…We found that radiation can damage the DNA of osteoblasts; induce apoptosis; reduce the differentiation, migration, and adhesion of osteoblasts, leading to lipogenesis of bone marrow mesenchymal stem cells (BMSCs) and reducing the source of osteoblasts; and increase the number of osteoclasts in bone tissue, while MSC treatment prevents these changes. …”
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11627
The triterpenoids-enriched extracts from Antrodia cinnamomea mycelia attenuate alcohol-induced chronic liver injury via suppression lipid accumulation in C57BL/6 mice
Published 2021-07-01“…ACT suppressed the triglyceride, total cholesterol and low-density lipoprotein levels, and enhanced high-density lipoprotein levels in serum or/and liver of chronic alcohol damaged mice. Combining with the pathological observations, ACT displayed an anti-steatosis effects to restrain the progress of ALD. …”
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11628
UAV With the Ability to Control with Sign Language and Hand by Image Processing
Published 2024-09-01“…Additionally, we developed robust debris and damage-resistant shielding mechanisms to safeguard the drone's integrity. …”
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11629
Health benefits of algae and marine-derived bioactive metabolites for modulating ulcerative colitis symptoms
Published 2025-02-01“…It has been reported that algal sulfated polysaccharides, peptides, pigments, polyphenols, and marine oil are useful for controlling ulcerative colitis via different pathways including modulating of TNF-α and other related inflammatory cytokines secretion, increasing the antioxidant enzymes [superoxide dismutase (SOD) and catalase(CAT)] activities, reduction of myeloperoxidase (MPO) activity and malondialdehyde (MDA) production, improving the intestinal barrier function and repairing histological damage in the colon. This review focused on the pathology of ulcerative colitis, pathogenesis and key inflammatory pathways, and the role of algae and marine-based metabolites for reduction of ulcerative colitis signs via alleviating the inflammation cytokines secretion, and improving the barrier function and gut microbiota.…”
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11630
Reprogramming the tumor immune microenvironment using engineered dual-drug loaded Salmonella
Published 2024-08-01“…Localized secretion of ClyA from SAM-FC induces immunogenic cancer cell death and promotes release of tumor-specific antigens and damage-associated molecular patterns, which establish long-term antitumor memory. …”
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11631
Discovery of Quinazolone Pyridiniums as Potential Broad-Spectrum Antibacterial Agents
Published 2025-01-01“…Preliminary explorations on antibacterial mechanisms revealed that compound <b>19a</b> could cause membrane damage, embed in intracellular DNA to hinder bacterial DNA replication, and induce metabolic dysfunction. …”
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11632
Effects of IQW and IRW on Inflammation and Gut Microbiota in ETEC-Induced Diarrhea
Published 2021-01-01“…The effects of the triple peptides IQW and IRW in gut-damage treatment were explored in this study via an enterotoxigenic Escherichia coli- (ETEC-) induced mouse model. …”
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11633
Young Adults’ Knowledge and Perceptions of Permanent Noise-Induced Tinnitus and its Influence on Behavioural Intentions
Published 2023-12-01“…In light of these results, recommendations for future noise-damage prevention campaigns are made.…”
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11634
Human Activity as a Growing Threat to Marine Ecosystems: Plastic and Temperature Effects on the Sponge <i>Sarcotragus spinosulus</i>
Published 2025-01-01“…Biomarker analyses revealed increased lysozyme, glutathione S-transferase, catalase, and superoxide dismutase activities in healthy sponges during August, while malondialdehyde levels, indicating oxidative damage, were higher in affected sponges. In conclusion, affected sponges exhibited elevated CFU counts of <i>Vibrio</i> spp. and reduced antioxidant and detoxification responses under elevated temperatures. …”
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11635
A Protective Role of Canonical Wnt/β-Catenin Pathway in Pathogenic Bacteria-Induced Inflammatory Responses
Published 2024-01-01“…A baseline extent of inflammation is supposed to be tightly associated with a sequence of immune-modulated processes, resulting in the protection of the host organism against pathogen invasion; however, as a matter of fact is that an uncontrolled inflammatory cascade is the main factor responsible for the host damage, accordingly suggesting a significant and indispensable involvement of negative feedback mechanism in modulation of inflammation. …”
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11636
REFINED ESTIMATES OF DIRECT PYROGENIC CARBON EMISSIONS IN RUSSIAN FORESTS BASED ON REMOTE MONITORING DATA FROM 2011 TO 2023
Published 2024-12-01“…In addition, we use new products of forest species and age structure, the level of fire damage to forest vegetation for mapping the type and fire severity, and the coefficients of fuel consumption in wood debris. …”
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11637
Oral Administration of Piperine as Curative and Prophylaxis Reduces Parasitaemia in Plasmodium berghei ANKA-Infected Mice
Published 2022-01-01“…Additionally, piperine showed an ability to protect organs (lungs, liver, spleen, and kidneys) from some damage in a dose-dependent manner. This study can be used as a basis for further discovery of novel chemotherapeutic or chemoprophylactic compounds.…”
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11638
Predicting Optimum Dilution Factors for BOD Sampling and Desired Dissolved Oxygen for Controlling Organic Contamination in Various Wastewaters
Published 2022-01-01“…High biochemical oxygen demand (BOD) concentrations in water minimize oxygen availability, damage ecosystem biodiversity, impair water quality, and spoil freshwater. …”
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11639
Study on Drainage of Pavement Layers and Improvement Strategies: Case Study
Published 2023-02-01“…Moisture intrusion is one of the main pavement damages that can decline the pavement surface conditions and reduce structural strength and load-carrying capacity. …”
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11640
Potential Analysis of Kavir & Desert Region and Makran Coasts In Order To Obtain Energy From the Sun Using Fuzzy Logic and AHP
Published 2021-12-01“…One of the most important energy sources in the world is solar energy, which is a renewable resource and does not cause any damage to the environment. Which all of these features justify using it as a clean energy source and economically viable cost.. …”
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