How the Suboxone Education Programme presented as a solution to risks in the Canadian opioid crisis: a critical discourse analysis by Quinn Grundy, Fiona Webster, Daniel Z Buchman, Sheryl Spithoff, Ross E G Upshur, Abhimanyu Sud, Matthew Strang

“…Within this context, this study examined how the ‘Suboxone Education Programme’, developed and delivered by a pharmaceutical company as part of a federally regulated risk management program, was presented as a solution to various kinds of risks relating to opioid use in public documents from medical institutions across Canada.Setting These documents were issued during the Canadian opioid crisis, a time when the involvement of industry in health policy was being widely questioned given industry’s role in driving the overprescribing of opioid analgesics and contributing to population-level harms.Design A critical discourse analysis of 69 documents collected between July 2020 and May 2021 referencing the Suboxone Education Program spanning 13 years (2007–2021) from medical, nursing and pharmacy institutions sourced from every Canadian province and territory. …”
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A Randomized, Double-Masked, Active-Controlled, Crossover Phase III Equivalence Study of Generic Dorzolamide 2% versus Innovator Trusopt® Eye Drop Solution in Subjects with Open-An... by Katharina Bell, Christina Korb, Christina Butsch, Bert Constantin Giers, Anna Beck, Alicja Strzalkowska, Christian Ruckes, Ulrike Klingberg, Norbert Pfeiffer, Katrin Lorenz

“…After washout, patients were randomized to reference product (Trusopt®) or test product (dorzolamide 2% eye drops, Rompharm Company SRL) for a 4-week period. Subsequent washout and crossover were performed. …”
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Collection accessions and source material as a determining factor for producing new melon cultivars by E. A. Varivoda, Т. G. Koleboshina, М. S. Kornilova

“…In total, during the period of 2015–2017, over 100 melon accessions were studied: 45 accessions from the VIR collection, 61 from various companies, and 12 developed at various research institutions. …”
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The effect of replacing red algae on histomorphology and enzymes of digestive tract of Nile tilapia, Oreochromis niloticus by Sanaz Kord, Rahim Abdi, Isaac Zamani, Rhima Peyghan

“…Materials and methods: A total of 120 pieces of tilapia with an average weight of 30 ± 1 g after acclimation for 6 weeks in 100-L aquariums were divided in 4 groups and three replicates (10 fish in each tank) and then fed with basic diet (BioMar Company, France) containing zero, 3%, 6%, and 9% red algae (C, T3%, T6% and T9%). …”
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Co-designing a film showcasing the dental experiences of community returners (ex-offenders) by Joelle Booth, Joelle Booth, Heather McMullen, Andrea Rodriguez, Vanessa Muirhead

“…A community film production company produced the film and used professional actors who had contact with the justice system to depict the characters in the film.ResultsThe final film, titled “My Story, My Words, My Mouth” explored themes such as self-care oral health behaviours, dental care provision in prison, access to healthcare, stigmatisation, disclosure and improving oral health to support societal reintegration. …”
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Society for Immunotherapy of Cancer: updates and best practices for multiplex immunohistochemistry (IHC) and immunofluorescence (IF) image analysis and data sharing by Ignacio I Wistuba, Michael T Tetzlaff, Carlo B Bifulco, Benjamin Green, Sacha Gnjatic, Scott J Rodig, Joel C Sunshine, Janis M Taube, Keith E Steele, Marlon C Rebelatto, David L Rimm, Ana Lako, Edwin R Parra, Guray Akturk, Michael Angelo, Shirley Greenbaum, Noah F Greenwald, Cyrus V Hedvat, Travis J Hollmann, Kurt A Schalper, Cláudia S Ferreira, Konstanty Korski, Emanuel Schenck, Michael J Surace, Jennifer H Yearley, Jeffrey S Roskes, Margaret Eminizer, Logan L Engle, Daniel Jiménez-Sánchez, Jamie Rodriguez-Canales, Alexander S Szalay

“…The current effort represents a complementary manuscript for mIHC/IF analysis focused on the associated image analysis and data management.Methods The Society for Immunotherapy of Cancer convened a task force of pathologists and laboratory leaders from academic centers as well as experts from pharmaceutical and diagnostic companies to develop best practice guidelines for the quantitative image analysis of mIHC/IF output and data management considerations.Results Best-practice approaches for image acquisition, color deconvolution and spectral unmixing, tissue and cell segmentation, phenotyping, and algorithm verification are reviewed. …”
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Improving the integrity and reproducibility of research that uses antibodies: a technical, data sharing, behavioral and policy challenge by M. Biddle, P. Stylianou, M. Rekas, A. Wright, J. Sousa, D. Ruddy, M. I. Stefana, K. Kmiecik, A. Bandrowski, R.A. Kahn, C. Laflamme, E. M. Krockow, H.S. Virk

“…This interacts with the batch-to-batch variability of these biological reagents, and the paucity of available characterization data for most antibodies, making it more difficult for researchers to choose high quality reagents and perform necessary validation experiments. The open-science company YCharOS works with major antibody manufacturers and knockout cell line producers to characterize antibodies, identifying high-performing renewable antibodies for many targets in neuroscience. …”
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Analyzing the rainfed wheat yield gap in Northwest Iran by Arash Mohammadzadeh, Yaser Azimzadeh, Ramin Lotfi, Esmail Zadhasan, Khoshnood Alizadeh, Hamid Hassaneian Khoshro

“…Wheat is one of the major crops in Iran, covering more than 36% of the total croplands and more than 70% of rainfed farmlands. However, the trend of crop yield in the past decades does not show promising performance and the average yield of rainfed wheat in Iran is as low as 1250 ​kg ​ha−1. …”
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Effect of potato glycoside alkaloids on mitochondria energy metabolism of Fusarium solani, the root rot pathogen of Lycium barbarum by Ruiyun Li, Bin Wang, Wei Chen, Chongqing Zhang, Nan Li, Yupeng Wang, Yuke Yan, Yuyan Sun, Jing He, Jing He

“…Furthermore, a total of 195 pathways were identified through KEGG analysis, with significant enrichment in critical pathways including pentose and glucuronate interconversions, propanoate metabolism, various types of N-glycan biosynthesis, the pentose phosphate pathway, and carbon fixation in photosynthetic organisms. …”
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Cs+ Adsorption and Pyrolytic Volume Reduction Performance of KR-01 Mixed Ion Exchange Resin by Weilei GUO, Hongyi GAO, Jinchi MAO, Renliang YUE, Haidi LIU

“…Cesium-137 (137Cs) is one of the most common radioactive substances in nuclear reactor wastewater, developing efficient Cs+ adsorbing materials is of paramount importance for sustainable development of nuclear energy, human health protection, and environmental conservation. The company has developed a KR-01 mixed ion exchange resin by blending the synthesized cation and anion exchange resins in a 1:1.8 mass ratio. …”
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Activated B Lymphocyte Inhibited the Osteoblastogenesis of Bone Mesenchymal Stem Cells by Notch Signaling by Mengxue Pan, Wei Hong, Ye Yao, Xiaoxue Gao, Yi Zhou, Guoxiang Fu, Yuanchuang Li, Qiang Guo, Xinxin Rao, Peiyuan Tang, Shengzhi Chen, Weifang Jin, Guoqiang Hua, Jianjun Gao, Xiaoya Xu

“…Osteoporosis did not happen in SPX rats which is still companied with a high increase of B lymphocytes. LPS-pretreated B lymphocytes suppressed the osteogenesis of BMSCs, but the normal B lymphocytes could not. …”
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Hybrid Quality-Based Recommender Systems: A Systematic Literature Review by Bihi Sabiri, Amal Khtira, Bouchra El Asri, Maryem Rhanoui

“…As a result, recommender systems have achieved considerable economic, social, and global advancements. Companies are improving their algorithms with hybrid techniques that combine more recommendation methodologies as these systems are a major research focus. …”
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Supporting Smart Manufacturing in the Space Industry: A Case Study by Ala Arman, Andrea Lombardo, Flavia Monti, Massimo Mecella

“…This paper focuses on how Industry 4.0 principles enhance data analysis and automation in space manufacturing, illustrated through a case study at an aerospace company, with a focus on the composite sandwich panel manufacturing line. …”
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mRNA technology as one of the promising platforms for the SARS-CoV-2 vaccine development by A. A. Ilyichev, L. A. Orlova, S. V. Sharabrin, L. I. Karpenko

“…After the genome sequence of SARS-CoV-2 (Severe acute respiratory syndrome-related coronavirus 2) was published and the number of infected people began to increase rapidly, many global companies began to develop a vaccine. Almost all known approaches to vaccine design were applied for this purpose, including inactivated viruses, mRNA and DNA-vaccines, vaccines based on various viral vectors, synthetically generated peptides and recombinant proteins produced in cells of insects and mammals. …”
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Carbidopa/levodopa dose elevation and safety concerns in Parkinson's patients: a cross-sectional and cohort design by Michael S Okun, Peter Schmidt, David W Brodell, Nicole T Stanford, Charles E Jacobson

“…Many patients will likely need to eclipse the 800 mg threshold and pharmacies and insurance companies should be aware of the requirements that may extend beyond approval limits.…”
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Homeland security video surveillance system utilising the internet of video things for smart cities by Yasser Ismail, Mohamed Hammad, Mahmoud Darwich, Wael Elmedany

“…This is because of the high cost of the video surveillance cameras and the sensor installations, and the non‐standardisation of security cameras and sensors manufacturing, which is due to the differentiated infrastructure of companies or organizations that provide home security. …”
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Environmental, social, and governance performance: The role of Chinese employee stock ownership plans by Yasi Liu, Shaun McDowell, Chunxiao Xue, Jianing Zhang

“…This study investigates how the ESG performance of publicly listed companies in China is influenced by employee stock ownership plans (ESOPs). …”
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Using group model building to frame the commercial determinants of dietary behaviour in adolescence – findings from online system mapping workshops with adolescents, policymakers a... by Yanaina Chavez-Ugalde, Frank De Vocht, Russell Jago, Martin White, Zoi Toumpakari

“…Policymakers and public health practitioners reflected on the power and the deep level of influence food companies exert on adolescents’ behaviour. They recognised that the coexisting influence of food marketing and social media on mental health and body image is not well reflected in current policy and research efforts. …”
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Integrated Business and Engineering Educational Experience for Medical Students in the Development of Pediatric Medical Devices by Jennifer J. Li, Jonathan Lee, Mayilone Sathialingam, Nhi Ha, Tamara Galoyan, Ethan Faye, Michael Kim, Tara Shelby, Rishabh Shah, Yelim Lee, Melissa Bent, Juan C. Espinoza

“…METHODS An internship program was developed by the Keck Translational Biotechnology Association and the West Coast Consortium for Technology & Innovation in Pediatrics (CTIP), a Food and Drug Administration-funded pediatric medical device accelerator. Students and companies applied to participate and were paired based on students’ interests and experience, and project plans were developed together. …”
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A multi-objective mathematical model for the multi-warehouse order picking system using Benders decomposition algorithm by Fatemeh Nikkhoo, Ali Hosseinzadeh Kashan, Bakhtiar Ostadi, Ehsan Nikbakhsh

“…The data related to the warehouses of a company producing sanitary products in Iran was used as a case study to validate the applicability of the proposed model, and its results were reported in the article.Findings: The proposed model's results indicate that CPLEX can solve these problems up to small sizes in an acceptable time. …”
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