Improving the integrity and reproducibility of research that uses antibodies: a technical, data sharing, behavioral and policy challenge by M. Biddle, P. Stylianou, M. Rekas, A. Wright, J. Sousa, D. Ruddy, M. I. Stefana, K. Kmiecik, A. Bandrowski, R.A. Kahn, C. Laflamme, E. M. Krockow, H.S. Virk

“…This interacts with the batch-to-batch variability of these biological reagents, and the paucity of available characterization data for most antibodies, making it more difficult for researchers to choose high quality reagents and perform necessary validation experiments. The open-science company YCharOS works with major antibody manufacturers and knockout cell line producers to characterize antibodies, identifying high-performing renewable antibodies for many targets in neuroscience. …”
Get full text

Effect of potato glycoside alkaloids on mitochondria energy metabolism of Fusarium solani, the root rot pathogen of Lycium barbarum by Ruiyun Li, Bin Wang, Wei Chen, Chongqing Zhang, Nan Li, Yupeng Wang, Yuke Yan, Yuyan Sun, Jing He, Jing He

“…Furthermore, a total of 195 pathways were identified through KEGG analysis, with significant enrichment in critical pathways including pentose and glucuronate interconversions, propanoate metabolism, various types of N-glycan biosynthesis, the pentose phosphate pathway, and carbon fixation in photosynthetic organisms. …”
Get full text

Cs+ Adsorption and Pyrolytic Volume Reduction Performance of KR-01 Mixed Ion Exchange Resin by Weilei GUO, Hongyi GAO, Jinchi MAO, Renliang YUE, Haidi LIU

“…Cesium-137 (137Cs) is one of the most common radioactive substances in nuclear reactor wastewater, developing efficient Cs+ adsorbing materials is of paramount importance for sustainable development of nuclear energy, human health protection, and environmental conservation. The company has developed a KR-01 mixed ion exchange resin by blending the synthesized cation and anion exchange resins in a 1:1.8 mass ratio. …”
Get full text

Activated B Lymphocyte Inhibited the Osteoblastogenesis of Bone Mesenchymal Stem Cells by Notch Signaling by Mengxue Pan, Wei Hong, Ye Yao, Xiaoxue Gao, Yi Zhou, Guoxiang Fu, Yuanchuang Li, Qiang Guo, Xinxin Rao, Peiyuan Tang, Shengzhi Chen, Weifang Jin, Guoqiang Hua, Jianjun Gao, Xiaoya Xu

“…Osteoporosis did not happen in SPX rats which is still companied with a high increase of B lymphocytes. LPS-pretreated B lymphocytes suppressed the osteogenesis of BMSCs, but the normal B lymphocytes could not. …”
Get full text

Hybrid Quality-Based Recommender Systems: A Systematic Literature Review by Bihi Sabiri, Amal Khtira, Bouchra El Asri, Maryem Rhanoui

“…As a result, recommender systems have achieved considerable economic, social, and global advancements. Companies are improving their algorithms with hybrid techniques that combine more recommendation methodologies as these systems are a major research focus. …”
Get full text

Supporting Smart Manufacturing in the Space Industry: A Case Study by Ala Arman, Andrea Lombardo, Flavia Monti, Massimo Mecella

“…This paper focuses on how Industry 4.0 principles enhance data analysis and automation in space manufacturing, illustrated through a case study at an aerospace company, with a focus on the composite sandwich panel manufacturing line. …”
Get full text

mRNA technology as one of the promising platforms for the SARS-CoV-2 vaccine development by A. A. Ilyichev, L. A. Orlova, S. V. Sharabrin, L. I. Karpenko

“…After the genome sequence of SARS-CoV-2 (Severe acute respiratory syndrome-related coronavirus 2) was published and the number of infected people began to increase rapidly, many global companies began to develop a vaccine. Almost all known approaches to vaccine design were applied for this purpose, including inactivated viruses, mRNA and DNA-vaccines, vaccines based on various viral vectors, synthetically generated peptides and recombinant proteins produced in cells of insects and mammals. …”
Get full text

Carbidopa/levodopa dose elevation and safety concerns in Parkinson's patients: a cross-sectional and cohort design by Michael S Okun, Peter Schmidt, David W Brodell, Nicole T Stanford, Charles E Jacobson

“…Many patients will likely need to eclipse the 800 mg threshold and pharmacies and insurance companies should be aware of the requirements that may extend beyond approval limits.…”
Get full text

Homeland security video surveillance system utilising the internet of video things for smart cities by Yasser Ismail, Mohamed Hammad, Mahmoud Darwich, Wael Elmedany

“…This is because of the high cost of the video surveillance cameras and the sensor installations, and the non‐standardisation of security cameras and sensors manufacturing, which is due to the differentiated infrastructure of companies or organizations that provide home security. …”
Get full text

Environmental, social, and governance performance: The role of Chinese employee stock ownership plans by Yasi Liu, Shaun McDowell, Chunxiao Xue, Jianing Zhang

“…This study investigates how the ESG performance of publicly listed companies in China is influenced by employee stock ownership plans (ESOPs). …”
Get full text

Using group model building to frame the commercial determinants of dietary behaviour in adolescence – findings from online system mapping workshops with adolescents, policymakers a... by Yanaina Chavez-Ugalde, Frank De Vocht, Russell Jago, Martin White, Zoi Toumpakari

“…Policymakers and public health practitioners reflected on the power and the deep level of influence food companies exert on adolescents’ behaviour. They recognised that the coexisting influence of food marketing and social media on mental health and body image is not well reflected in current policy and research efforts. …”
Get full text

A multi-objective mathematical model for the multi-warehouse order picking system using Benders decomposition algorithm by Fatemeh Nikkhoo, Ali Hosseinzadeh Kashan, Bakhtiar Ostadi, Ehsan Nikbakhsh

“…The data related to the warehouses of a company producing sanitary products in Iran was used as a case study to validate the applicability of the proposed model, and its results were reported in the article.Findings: The proposed model's results indicate that CPLEX can solve these problems up to small sizes in an acceptable time. …”
Get full text

Identification of duplicate accessions in the sweet maize collection by means of zein electrophoresis by V. V. Sidorova, Yu. A. Kerv, A. V. Konarev

“…The leading seed-growing companies and research institutions around the world are engaged in breeding this crop. …”
Get full text

Evaluation of Sharia-based Sustainability Reporting Framework Influenced by the Emergence of Metaverse Axes in Accounting by Hossein Keshavarzi Nejhad, Maryam Shahri, Vahid Oskou, Mohammad Reza Abdoli

“…The obtained results indicate that Sharia-based sustainability reporting can lead to the grounding of anti-corruption social behaviors and Islamic financing methods in companies' strategies and thus provide higher accountability to stakeholders.…”
Get full text

Identification of antibiotic use patterns in poultry farms in the southwest region of Bangladesh by Sarder Safiqul Islam, Ratna Ghosh, Md. Shafiqul Islam, Minhazul Abedin Sun, Mustajabur Rahman, Dhiman Mondol

“…The use of antibiotics was suggested by various people such as veterinary doctors (35.56%), animal health workers (23.33%), drug company representatives (20.00%) and self (5.56%). …”
Get full text

In silico methods for immunogenicity risk assessment and human homology screening for therapeutic antibodies by Aimee E. Mattei, Andres H. Gutierrez, Soorya Seshadri, Jacob Tivin, Matt Ardito, Amy S. Rosenberg, William D. Martin, Anne S. De Groot

“…To facilitate larger scale analyses and accelerate preclinical immunogenicity risk assessment, our group developed an integrated web-based platform called ISPRI, (Immunogenicity Screening and Protein Re-engineering Interface) that provides hands-on access through a secure web-based interface for scientists working in large and mid-sized biotech companies in the US, Europe, and Japan. This toolkit has evolved and now contains an array of algorithms that can be used individually and/or consecutively for immunogenicity assessment and protein engineering. …”
Get full text

Examines The Impact of Product And Service Quality On Customer Satisfaction at PT. BMTP With Personal Branding by Andi Nadirah M., Indrawan, Suparman Parintak, Anne Attas, Burhanuddin Harahap

“…Originality/value (State of the art): Personal branding can improve customers' perceptions of the company's product and service quality, leading to increased customer satisfaction. …”
Get full text

Comprehensive analysis of histophysiology, transcriptomics and metabolomics in goslings exposed to gossypol acetate: unraveling hepatotoxic mechanisms by Jun Yu, Jun Yu, Haiming Yang, Jian Wang, Zixin Huang, Shi Chen, Hongchang Zhao, Jun Wang, Zhiyue Wang

“…Key affected pathways included carbon metabolism, glycolysis/gluconeogenesis, pyruvate metabolism, propanoate metabolism, TCA cycle, fatty acid degradation, primary bile acid biosynthesis, tryptophan metabolism, cysteine and methionine metabolism, focal adhesion, and the PPAR signaling pathway. …”
Get full text

Design and assembly of plant-based COVID-19 candidate vaccines: reсent development and future prospects by E. A. Uvarova, P. A. Belavin, E. V. Deineko

“…With two plant expression systems – stable and transient – as examples, the development of work on the creation of recombinant subunit vaccines against COVID-19 in various laboratories and commercial companies is shown. The authors emphasize that plant expression systems have promise for the development of not only protective means under conditions of rapid response (subunit vaccines), but also therapeutic agents in the form of monoclonal antibodies against COVID-19 synthesized in plant cells.…”
Get full text

Established Numerical Techniques for the Structural Analysis of a Regional Aircraft Landing Gear by F. Caputo, A. De Luca, A. Greco, A. Marro, A. Apicella, R. Sepe, E. Armentani

“…In particular, Magnaghi Aeronautica S.p.A. Company performed the experimental test, consisting of a drop test according to EASA CS 25 regulations. …”
Get full text