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Assessment of the Ground Vulnerability in the Preveza Region (Greece) Using the European Ground Motion Service and Geospatial Data Concerning Critical Infrastructures
Published 2025-01-01“…The findings provide valuable insights for local authorities and other stakeholders, who will greatly benefit from the information gathered from this study, which will lay the groundwork for wise decision-making and the creation of practical plans to strengthen the resistance of critical infrastructures to ground motion.…”
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Multicenter Surveillance of Pseudomonas aeruginosa Isolates From Blood: Clinical Distribution Characteristics and Antibiotic Resistance Trends in Hebei Province, China (2016–...
Published 2025-02-01“…Predominantly, patients were in the hematology (20.7%) and critical care medicine (18.4%) departments. During the monitoring period, the resistance rate of P. aeruginosa to various antibacterial drugs, such as aminoglycosides, fluoroquinolones, and carbapenems, decreased to varying degrees, with an average resistance rate of less than 20.0% over six years. …”
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Molecular characterization of ST15 carbapenem-resistant Klebsiella pneumoniae isolated in a single patient
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Phylogenetic Aspects of Antibiotic Resistance and Biofilm Formation of P. aeruginosa Isolated from Clinical Samples
Published 2024-01-01“…Biofilm production and drug resistance phenomenon play a critical role in P. aeruginosa infections. …”
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Targeted Next-Generation Sequencing in Pneumonia: Applications in the Detection of Responsible Pathogens, Antimicrobial Resistance, and Virulence
Published 2025-01-01“…Bing Liu,1– 3,* Zhiyao Bao,1– 3,* Wei Chen,1– 3,* Xiaotong Xi,4,5,* Xiao Ge,1– 3 Jun Zhou,1– 3 Xiaoyan Zheng,6 Peipei Zhang,4,5 Wanglong Deng,4,5 Ran Ding,4,5 Min Zhou,1– 3 Jie Fang7 1Department of Pulmonary and Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People’s Republic of China; 2Institute of Respiratory Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People’s Republic of China; 3Shanghai Key Laboratory of Emergency Prevention, Diagnosis and Treatment of Respiratory Infectious Diseases, Shanghai, 200025, People’s Republic of China; 4State Key Laboratory of Neurology and Oncology Drug Development, Jiangsu Simcere Diagnostics Co., Ltd., Nanjing Simcere Medical Laboratory Science Co., Ltd., Nanjing, 210018, People’s Republic of China; 5Nanjing Simcere Medical Laboratory Science Co., Ltd., Nanjing, 210018, People’s Republic of China; 6Department of Pulmonary and Critical Care Medicine, Zhoushan Branch of Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Zhoushan, 316000, People’s Republic of China; 7Department of Pharmacy, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jie Fang, Department of Pharmacy, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197, Rui Jin 2nd Road, Shanghai, 200025, People’s Republic of China, Email fj40517@rjh.com.cn Min Zhou, Department of Pulmonary and Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197, Rui Jin 2nd Road, Shanghai, 200025, People’s Republic of China, Email doctor_zhou_99@163.comBackground: Targeted next-generation sequencing (tNGS) is a high-throughput and cost-effective diagnostic alternative for pneumonia, with the ability to simultaneously detect pathogens, antimicrobial resistance genes, and virulence genes. …”
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Artesunate, EDTA, and colistin work synergistically against MCR-negative and -positive colistin-resistant Salmonella
Published 2025-02-01“…Discovering new strategies to combat the multidrug-resistant bacteria constitutes a major medical challenge of our time. …”
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128
Nonviolent resistance as a strategy of agitation - impeding or promoting unity through communication in South Africa?
Published 2022-11-01“…By means of critical-analytical argumentation key aspects of nonviolent resistance are posited, placed in historical context, and applied to socio-political reality In South Africa. …”
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129
Metabolomics profiling reveals p-aminobenzoic acid enhances resistance to Fusarium head blight in wheat
Published 2025-02-01“…Abstract Fusarium head blight (FHB) not only causes severe yield losses but also mycotoxin contamination in wheat, posing a serious threat to food security and public health. The mechanisms of resistance to FHB in wheat are critical for effective prevention and control of the pathogen. …”
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Identification of mitochondrial carrier homolog 2 as an important therapeutic target of castration-resistant prostate cancer
Published 2025-02-01“…Abstract We here investigate the expression of the mitochondrial carrier homolog 2 (MTCH2) and its potential function in castration-resistant prostate cancer (CRPC). Bioinformatic analyses reveal that MTCH2 overexpression is associated with critical clinical parameters of prostate cancer. …”
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131
A Study of Composite Salt Erosion Resistance of Nano-Modified Cement Mortar in Early Ages
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WNT11 Promotes immune evasion and resistance to Anti-PD-1 therapy in liver metastasis
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133
The antibiotic procurement saga: a long-neglected stewardship target to combat antimicrobial resistance in Pakistan
Published 2025-02-01“…However, flawed procurement modules result in poor antibiotic supply management within health facilities of low- and middle-income countries (LMICs), including Pakistan, exacerbating antimicrobial resistance (AMR). This study seeks to understand hospital pharmacists’ perspectives on the antibiotic procurement process, its efficiency in ensuring consistent access to antibiotics, and the role of clinical pharmacists in rational procurement. …”
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Multidrug Resistance Tuberculosis in the Context of Co-Infection in Ethiopia: A Systematic Review and Meta-Analysis
Published 2025-02-01“…Abstract The rise of multidrug-resistant tuberculosis (MDR-TB) remains a critical public health challenge, particularly in developing countries like Ethiopia. …”
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Activity of Antiseptics Against <i>Pseudomonas aeruginosa</i> and Its Adaptation Potential
Published 2025-01-01“…Background/Objectives: <i>Pseudomonas aeruginosa</i> rapidly acquires antibiotic resistance and demonstrates increasing tolerance to antiseptics. …”
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Trajectory of peripheral inflammation during index ECT in association with clinical outcomes in treatment-resistant depression
Published 2025-02-01“…Improved understanding of these processes may provide critical insight into effective intervention for treatment-resistant depression (TRD). …”
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Prevalence and Molecular Characterization of Carbapenemase-Producing Multidrug-Resistant Bacteria in Diabetic Foot Ulcer Infections
Published 2025-01-01“…The increasing incidence of multidrug-resistant (MDR) bacteria in DFUs complicates treatment strategies and worsens patient prognosis. …”
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Epidemiology and Resistance Profiles of Bacteria Isolated From Blood Samples in Septic Patients at Emergency Department Admission: A 6-Year Single Centre Retrospective Analysis Fro...
Published 2025-03-01“…Age is a critical factor in guiding empirical antibiotic therapy in the ED.…”
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Quinazoline scaffold as a target for combating microbial resistance: Synthesis and antimicrobial profiling of quinazoline derivatives
Published 2025-01-01“…Synthetic methods include transition metal-mediated reactions, microwave-assisted techniques, and Aza reactions. The review critically evaluates the efficacy of quinazoline derivatives against drug-resistant pathogens and explores avenues for developing quinazoline-based antimicrobials. …”
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