Microstructural optimization by two-step tempering treatment and quantitative analysis of microstructure effect on the toughness at −40 °C in CrNiMoV steel by Li Wang, Junwei Qin, Yuzhi Zhu, Kaixuan Chen, Yanlin Wang, Zidong Wang

“…Specifically, the intrinsic relationship between −40 °C impact resistance and microstructure were quantitatively investigated using CVN impact tests, SEM, EBSD, and TEM characterization. …”
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Perforin-2 is dispensable for host defense against Aspergillus fumigatus and Candida albicans by Mariano A. Aufiero, Li-Yin Hung, De'Broski R. Herbert, Tobias M. Hohl

“…The World Health Organization has classified A. fumigatus and C. albicans as critical priority fungal pathogens due to the emergence of drug resistance and the increasing number of susceptible individuals across the globe. …”
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Verification of the Introgression of <i>Narenga porphyrocoma</i> Germplasm into <i>Saccharum officinarum</i> Using Molecular Markers and GISH Analysis by Gang Wang, Wei Zhang, Yuanxia Qin, Qingdan Wu, Qinggan Liang, Jiantao Wu, Shengren Sun, Zhuqing Wang, Yuxing An, Jianqiang Wang, Qinnan Wang, Hailong Chang

“…Sugarcane (<i>Saccharum</i> spp.), a critical crop for sugar and bioenergy production, faces challenges in genetic improvement due to limited genetic diversity from selective breeding. …”
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Nanoparticle-mediated gene delivery techniques in plant systems by Kuber Shivashakarappa, Sureshbabu Marriboina, Korsi Dumenyo, Ali Taheri, Zeinab Yadegari

“…However, delivering the nanoparticles and cargo complexes into plants is a critical step of the gene delivery process, and have not been thoroughly explored. …”
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Difficulties faced by physicians from four European countries in rebutting antivaccination arguments: a cross-sectional study by Fernanda Rodrigues, Cornelia Betsch, Pierre Verger, Harriet Fisher, Philipp Schmid, Dawn Holford, Angelo Fasce, Amanda Garrison, Linda Karlsson, Frederike Taubert, Stephan Lewandowsky, Anna Soveri

“…Introduction Physicians play a critical role in encouraging their patients to get vaccinated, in part by responding to patients’ concerns about vaccines. …”
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Liquid chromatography-high resolution mass spectrometry based analysis of persistent mobile organic compounds in aqueous samples: Method development and optimization by Kyriaki Anagnostopoulou, Vasileios Alampanos, Eleni Evgenidou, Dimitra A. Lambropoulou

“…Persistent Mobile Organic Compounds (PMOCs) represent a critical threat to water resources due to their high solubility, resistance to degradation, and potential toxicity, posing risks to human health and ecosystems. …”
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Militancia, destrucción y resistencias de las mujeres en la Unión Patriótica by Carlos Andrés Torres Mateus

“…Abstract This article proposes a brief overview —with a critical analysis— of the history of women in the Unión Patriótica. …”
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Synthesis and evaluation of nitrochromene derivatives as potential antileishmanial therapeutics through biological and computational studies by Niloofar Javid, Ali Asadipour, Ehsan Salarkia, Mohammad Amin Langarizadeh, Fatemeh Sharifi, Mohammad Mahdavi, Bagher Amirheidari, Aida Iraji, Hojjat Rezaiezadeh, Gholamreza Hassanpour, Yaghoub Pourshojaei

“…This study endeavors to address this critical need by focusing on the design and synthesis of a series of novel compounds. …”
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The analysis of structural fatigue under cyclic temperature loads by I. Yu. Lesnyak, Z. N. Sokolovskiy, S. V. Gavrilenko

“…The formulation of the problem of studying the deformations of materials of structures operating under conditions of cyclic alternating temperature loads using the theories of cyclic strength, low-cycle fatigue and crack resistance is presented. It is assumed that at 16 revolutions of an orbital object around the Earth (the number of temperature loading cycles n ≥ 1,2105 ), cracking occurs or the size of existing cracks increases to a critical size from low-cycle fatigue. …”
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Possible Superconductivity Transition in Nitrogen‐Doped Lutetium Hydride Observed at Megabar Pressure by Xingbin Zhao, Yu Huang, Shuailing Ma, Hao Song, Yanwei Cao, Hao Jiang, Yanping Huang, Tian Cui

“…Resistivity measurements in the Fm3¯m‐LuH3±xNy phase under varying magnetic fields exhibited characteristics consistent with superconductivity, with an upper critical field μ0Hc2(0) of 3.3 T measured at 163 GPa. …”
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Obhajoba oprávněného vzdoru vůči svrchovaným vládcům v díle Christophera Goodmana by Miroslav Beneš

“…Christopher Goodman was well-known thanks to his critical work ’How Superior Powers Ought to Be Obeyed by Their Subjects and Wherein They May Lawfully by God’s Word Be Disobeyed and Resisted’. …”
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Modulating DDAH/NOS Pathway to Discover Vasoprotective Insulin Sensitizers by Li Lai, Yohannes T. Ghebremariam

“…Insulin resistance syndrome (IRS) is a configuration of cardiovascular risk factors involved in the development of metabolic disorders including type 2 diabetes mellitus. …”
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Understanding regular exercise behavior in frail older adults: a structural equation model based on social-cognitive variables by Shiqi Yu, Jie Lin, Siping Song, Shuqi Huang, Fan Liu, Mingzhao Xiao

“…Integrating self-efficacy and outcome expectations into further exercise promotion is critical. Patient-centered approach is essential for developing more effective and sustainable exercise interventions.…”
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Bibliometric analysis of glycolysis and prostate cancer research from 2004 to 2024 by Congxu Zhu, Jingjing Yang, Lumei Liu, Bonan Li, Tiansong Sun, Wen Sheng, Qinghu He

“…Enhanced glycolysis and excessive lactate secretion are recognized as critical factors driving the progression of various cancers. …”
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Phylogenomic analysis reveals exceptions to the co-evolution of ZAR1 and ZRK immune gene families in plants by Li Yang, Shengyi Liu, M. Eric Schranz, Klaas Bouwmeester

“…Abstract Background HOPZ-ACTIVATED RESISTANCE 1 (ZAR1) is a nucleotide-binding leucine-rich repeat (NLR) protein functioning as a recognition hub to initiate effector-triggered immunity against bacterial pathogens. …”
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Comparison of different severe obesity definitions in predicting future cardiometabolic risk in a longitudinal cohort of children by Gilles Paradis, Melanie Henderson, Lisa Kakinami, Angelo Tremblay, Anna Smyrnova

“…Whether SO definitions differentially predict cardiometabolic disease risk is critical for proper clinical care and management but is unknown.Design Prospective cohort studySetting SO definitions were applied at baseline (2005–2008, Mage=9.6 years, n=548), and outcomes (fasting lipids, glucose, homoeostatic model assessment (HOMA-IR) and blood pressure) were assessed at first follow-up (F1: 2008–2011, Mage=11.6 years) and second follow-up (2015–2017, Mage=16.8 years) of the Quebec Adipose and Lifestyle Investigation in Youth cohort in Montreal, Quebec.Participants Respondents were youth who had at least one biological parent with obesity.Primary outcome measures Unfavourable cardiometabolic levels of fasting blood glucose (≥6.1 mmol/L), insulin resistance (HOMA-IR index ≥2.0), high-density lipoprotein &lt;1.03 mmol/L, low-density lipoprotein ≥2.6 mmol/L and triglycerides &gt;1.24 mmol/L. …”
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Collection of microorganisms of ICG SB RAS as a genetic resource for biotechnology by A. V. Bryanskaya, Y. E. Uvarova, A. S. Rozanov, N. M. Slynko, V. N. Shlyakhtun, K. V. Starostin, E. A. Demidov, E. V. Lazareva, O. P. Taran, S. E. Peltek

“…Genetic knowledge of microorganisms plays a critical role in the creation of new biotechnologies, since the effectiveness of any biotechnology is determined by the particular qualities of the structurally functional organization of molecular-genetic systems and their components used for the production of targeted products. …”
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Green building development utilising modified fired clay bricks and eggshell waste by Wafaa Soliman, Yasser M. Z. Ahmed, Ahmed Ghitas, Abdel‑Hamid El‑Shater, M. Abdelhamid Shahat

“…A crucial factor in raising a building’s energy efficiency involves utilizing bricks with high thermal resistance. This issue is accompanied by another critical challenge: recycling and disposing of waste in a way that is both economically and environmentally beneficial, including using it to fuel industrial growth, in order to reduce the harmful effects of waste on the environment as waste generation in our societies grows. …”
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MicroRNA-21 as a Regulator of Cancer Stem Cell Properties in Oral Cancer by Milica Jaksic Karisik, Milos Lazarevic, Dijana Mitic, Maja Milosevic Markovic, Nicole Riberti, Drago Jelovac, Jelena Milasin

“…In conclusion, miRNA-21 plays a critical role in the regulation of oral cancer CD44+ cells properties. …”
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Genome-wide characterization and expression analysis of the ADF gene family in response to salt and drought stress in alfalfa (Medicago sativa) by Mengmeng Shi, Yike Wang, Peng Lv, Yujie Gong, Qi Sha, Xinyan Zhao, Wen Zhou, Lingtao Meng, Zegang Han, Lingxiao Zhang, Lingxiao Zhang, Yongwang Sun, Yongwang Sun

“…Furthermore, the majority of MsADF genes were induced by salt and drought stress by more than two-fold, with MsADF1, 2/3, 6, and 9 being highly induced, suggesting their critical role in resistance to abiotic stress. These results provide comprehensive information on the MsADF gene family in alfalfa and lay a solid foundation for elucidating their biological function.…”
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