Showing 221 - 240 results of 885 for search 'Critical Resistance', query time: 0.08s Refine Results
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    Targeting of the HER2/HER3 signaling axis overcomes ligand‐mediated resistance to trastuzumab in HER2‐positive breast cancer by Satomi Watanabe, Kimio Yonesaka, Junko Tanizaki, Yoshikane Nonagase, Naoki Takegawa, Koji Haratani, Hisato Kawakami, Hidetoshi Hayashi, Masayuki Takeda, Junji Tsurutani, Kazuhiko Nakagawa

    Published 2019-03-01
    “…HER3 ligand (heregulin)‐dependent HER2‐HER3 interactions play a critical role in the evasion of apoptosis and are therefore a target for oncotherapy to treat HER2‐positive breast cancer. …”
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    Article
  3. 223

    Multidrug-resistant ESBL E. coli in urban surface waters and public health implications: A Case Study from Goranchatbari, Dhaka by Md. Sakib Hossain, Ahmed Ishtiaque Amin Chowdhury, Mohammad Rafiqul Islam, Ripan Kirtunia, Md. Foysal Abedin, Mohammad Atique Ul Alam, Shampa, Sonia Binte Murshed, Md Shadman Sakib, Siam Alam, M. Shahjahan Mondal, Zahid Hayat Mahmud

    Published 2025-02-01
    “…The presence of pathogenic extended spectrum β-lactamase (ESBL) producing E. coli in surface water poses a critical public health concern by increasing the risk of waterborne diseases and spreading multidrug-resistant (MDR) infections. …”
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    Article
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    Enhanced bacteriostatic effects of phage vB_C4 and cell wall-targeting antibiotic combinations against drug-resistant Aeromonas veronii by Xin Cao, Yanqiong Tang, ZhenZhang Lu, Xiang Ma, Hong Li, Xue Chi, Juanjuan Li, Zhu Liu

    Published 2025-02-01
    “…ABSTRACT Aeromonas veronii is a vital zoonotic pathogen known for its extensive drug resistance and ability to form biofilms, which contribute to its antibiotic resistance. …”
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    Article
  9. 229

    A Comparative Analysis of Morphological Characteristics between Endangered Local Prickly Pear and the Newly Introduced Dactylopius opuntiae-Resistant Species in Eastern Morocco by Ahmed Marhri, Mehdi Boumediene, Aziz Tikent, Reda Melhaoui, Kawtar Jdaini, Aatika Mihamou, Hana Serghini-Caid, Ahmed Elamrani, Christophe Hano, Malika Abid, Mohamed Addi

    Published 2024-01-01
    “…The objective of the present investigation is to explore the morphological parameters of Opuntia robusta and Opuntia dillenii which are resistant to the white cochineal (Dactylopius opuntiae), as well as the local prickly pear that is currently threatened with extinction. …”
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  10. 230

    A Direct and Sensitive Method for Determination of 5-Fluorouracil in Colorectal Cancer Cells: Evaluating the Effect of Stromal Cell on Drug Resistance of Cancer Cells by Fengjing Xu, Zhipeng Wang, Xinhua Song, Mengwei Zhang, Lili Cui, Yanping Liu, Hongxia Yan, Shouhong Gao, Yan Liu, Wansheng Chen

    Published 2021-01-01
    “…Fibroblasts in the stroma play a critical role in tumor evolution. In this study, we assessed the influence of colonic fibroblasts on colon cancer cells treated with 5-fluorouracil (5-FU), and mouse colon cancer cell lines MC38 and colonic fibroblasts NIH3T3 were used in this study. …”
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    Challenging Discourses of Sexual Violence on X: The Linguistic Representation of Victims and Perpetrators in Kavanaugh’s Confirmation Process by Patricia Palomino Manjón

    Published 2024-07-01
    “…In addition, the analysis revealed the creation of discursive protests on X to resist patriarchal discourses and practices in American society.…”
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    TRIM25: A Global Player of Cell Death Pathways and Promising Target of Tumor-Sensitizing Therapies by Wolfgang Eberhardt, Usman Nasrullah, Josef Pfeilschifter

    Published 2025-01-01
    “…Therapy resistance still constitutes a common hurdle in the treatment of many human cancers and is a major reason for treatment failure and patient relapse, concomitantly with a dismal prognosis. …”
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  17. 237

    Theoretical assessment of the relative incidences of sensitive andresistant tuberculosis epidemic in presence of drug treatment by Silvia Martorano Raimundo, Hyun Mo Yang, Ezio Venturino

    Published 2014-02-01
    “…We identify the steady states of the model toanalyse their stability.We establish threshold conditions for possible scenarios:elimination of sensitive and resistant strains and coexistence of both.We find that the effective reproductive number iscomposed of two critical values, relative reproductive number for drug-sensitiveand drug-resistant strains.Our results imply that thepotential for the spreading of the drug-resistant strain should be evaluated withinthe context of several others factors.We have also found that even the considerably less fit drug-resistant strainscan lead to a high MDR-TB incidence, because the treatment is less effective against them.…”
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  18. 238

    Point prevalence survey of antibiotics in a pediatric tertiary hospital in the Republic of Panama by Ximena Norero, Dora Estripeaut, Elizabeth Castaño, Jacqueline Levy, Paola Lichtenberger, José Pablo Díaz-Madriz, José Luis Bustos, Robin Rojas Cortés, Gabriel Levy-Hara

    Published 2025-01-01
    “…The findings suggest it is necessary to assess the need for ampicillin, gentamicin, and piperacillin-tazobactam use in patients admitted to pediatric critical care units, with special emphasis on children with pneumonia and sepsis diagnosis, the most common pathologies for which an antimicrobial was prescribed.…”
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  19. 239

    Structural characteristics, functions, and counteracting strategies of biofilms in Staphylococcus aureus by Yanze Xia, Zhenghui Hu, Qiyuan Jin, Qi Chen, Chenhao Zhao, Rui Qiang, Zonggang Xie, Liubing Li, Haifang Zhang

    Published 2025-01-01
    “…The formation of biofilms contributes to the emergence of resistant strains, further diminishing the efficacy of antibiotics. …”
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  20. 240

    Variation and simulation of tomato transpiration in a greenhouse under different ventilation modes by Jiankun Ge, Sen Wang, Xuewen Gong, Yuhao Zhu, Zihui Yu, Yanbin Li

    Published 2025-03-01
    “…Meteorological conditions inside the greenhouse and water consumption indicators were analyzed to improve the Penman-Monteith (P-M) model’s resistance parameters (canopy resistance, rc and aerodynamic resistance, ra). …”
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    Article