Cost of TB care and equity in distribution of catastrophic TB care costs across income quintiles in India by Kathiresan Jeyashree, Jeromie W. V. Thangaraj, Devika Shanmugasundaram, Sri Lakshmi Priya Giridharan, Sumit Pandey, Prema Shanmugasundaram, Sabarinathan Ramasamy, Venkateshprabhu Janagaraj, Sivavallinathan Arunachalam, Rahul Sharma, Vaibhav Shah, Bhavani Shankara Bagepally, Joshua Chadwick, Hemant Deepak Shewade, Aniket Chowdhury, Swati Iyer, Raghuram Rao, Sanjay K. Mattoo, Manoj V. Murhekar

“…Direct costs accounted for 34% of the total costs, with a median of US$78.4 (43.3, 153.6), while indirect costs had a median of US$279.8 (18.9,699.4). …”
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Identifying pre-diabetes ‘hotspots’ in Northern California using geospatial analysis: opportunities to target diabetes prevention strategies and improve health equity by Tannaz Moin, Luis A Rodriguez, Obidiugwu Kenrik Duru, Julie Schmittdiel, Tainayah W Thomas, Maher Yassin, Yelba Castellon-Lopez

“…Individual-level characteristics were derived from electronic health records and administrative data, while census-level characteristics were derived from the 2019 American Community Survey.Results A total of 760 044 adults met the study inclusion criteria and 40% had pre-diabetes. …”
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Comparing the protection of heterologous booster of inhaled Ad5-nCoV vaccine and hybrid immunity against Omicron BA.5 infection: a cohort study of hospital staff in China by Kai Wang, Ting Zeng, Zihao Guo, Jing Liang, Shengzhi Sun, Yongkang Ni, Chunyan Yan, Liang Yin, Lan Wang, Hui Li, Kailu Wang, Marc K.C. Chong, Naijun Tang, Jianghong Dai, Zhaohui Luo, Shi Zhao

“…Our findings supported the rollout of a heterologous vaccination strategy regardless of preexisting vaccine coverage.…”
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Safety and efficacy of edoxaban monotherapy after bioabsorbable polymer everolimus-eluting stent implantation in a human-like coronary atherosclerotic porcine model by Daisuke Kitano, Suguru Migita, Yuxin Li, Yutaka Koyama, Katsunori Fukumoto, Sayaka Shimodai-Yamada, Akira Onishi, Daiichiro Fuchimoto, Shunichi Suzuki, Yoshiyuki Nakamura, Atsushi Hirayama, Hiroyuki Hao, Yasuo Okumura

“…No in-stent thrombi were observed in either group. iMap-IVUS findings indicated that edoxaban monotherapy significantly suppressed the increase in lipidic and necrotic plaque area while promoting fibrotic area expansion. Conclusions: Edoxaban monotherapy demonstrated superior efficacy in suppressing neointimal hyperplasia and stabilizing coronary plaques compared to DAPT with equivalent safety in preventing in-stent thrombus formation. …”
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Cervical precancer screening using self-sampling, HPV DNA testing, and mobile colposcopy in a hard-to-reach community in Ghana: a pilot study by Kofi Effah, Ethel Tekpor, Comfort Mawusi Wormenor, John Allotey, Yaa Owusu–Agyeman, Seyram Kemawor, Dominic Agyiri, Johnpaul Amenu, Jonathan M. Gmanyami, Martin Adjuik, Kwabena Obeng Duedu, Joyce B. Der, Nana Owusu Mensah Essel, Margaret Kweku

“…Abstract Background The World Health Organization has set ambitious goals to eliminate cervical cancer, necessitating evidence on increasing coverage and access to screening and treatment in high-burden areas. …”
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Advancements and challenges in personalized neoantigen-based cancer vaccines by Parminder Singh, Parminder Singh, Mahalaqua Nazli Khatib, Roopashree R, Mandeep Kaur, Manish Srivastava, Amit Barwal, G. V. Siva Rajput, Pranchal Rajput, Rukshar Syed, Gajendra Sharma, Sunil Kumar, Muhammed Shabil, Sakshi Pandey, Manvinder Brar, Ganesh Bushi, Rachana Mehta, Sanjit Sah, Sanjit Sah, Sanjit Sah, Khang Wen Goh, Khang Wen Goh, Prakasini Satapathy, Prakasini Satapathy, Abhay M. Gaidhane, Shailesh Kumar Samal

“…Additionally, these vaccines contribute towards achieving Sustainable Development Goal 3.8, promoting universal health coverage by advancing access to safe and effective cancer treatments. …”
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Number of tetanus toxoid injections before birth and associated factors among pregnant women in low and middle income countries: Negative binomial poisson regression by Alebachew Ferede Zegeye, Tadesse Tarik Tamir, Enyew Getaneh Mekonen, Mohammed Seid Ali, Almaz Tefera Gonete, Masresha Asmare Techane, Mulugeta Wassie, Alemneh Tadesse Kassie, Medina Abdela Ahmed, Sintayehu Simie Tsega, Yilkal Abebaw Wassie, Berhan Tekeba, Belayneh Shetie Workneh

“…Therefore, the ministries of health in low and middle-income countries should give attention to those women who had no antenatal care visits and women from poor wealth quantiles while designing policies and strategies.…”
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Analytical validation of Aspyre Clinical Test for Lung (Blood): A multiplexed PCR and pyrophosphorolysis-based assay for detecting actionable NSCLC variants in plasma cfDNA and cfR... by Ryan Thomas Evans, Katherine Elizabeth Knudsen, Elizabeth Gillon-Zhang, Julia Natalie Brown, Candace King, Mary Beth Rossi, Cory Kiser, James Alexander Schaffernoth, Amanda Shull Green, Ana-Luisa Silva, Kristine von Bargen, Justyna Malgorzata Mordaka, Rebecca Natalie Palmer, Alessandro Tomassini, Alejandra Collazos, Simonetta Andreazza, Iyelola Turner, Chau Ha Ho, Dilyara Nugent, Jinsy Jose, Christina Xyrafaki, Prarthna Barot, Magdalena Stolarek-Januszkiewicz, Sam Abujudeh, Eleanor Ruth Gray, Jeffrey Gregg, Wendy Jo Levin, Barnaby William Balmforth, Kelly Pitts, Shari Brown

“…NGS-based methods require high sample quality, high sequencing depth and associated cost, with complex workflows, while PCR assays are limited in variant coverage. …”
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Identification and characterization of a male-specific region in largemouth bass (Micropterus Salmoides) by whole-genome sequencing, resequencing and genomics comparison by Xinhui Zhang, Xinhui Zhang, Xinhui Zhang, Junjian Dong, Zhiqiang Ruan, Fengying Gao, Wenchuan Zhou, Xinxin You, Jieming Chen, Qiong Shi, Qiong Shi, Xing Ye, Chengfei Sun

“…They were homozygous in females while heterozygous in males. We therefore speculate that largemouth bass owns a XX/XY sex determination system. …”
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Economic burden of Chagas disease in Brazil: a nationwide cost-of-illness studyResearch in context by Mônica Viegas Andrade, Kenya Valeria Micaela de Souza Noronha, Aline de Souza, Nayara Abreu Julião, André Soares Motta-Santos, Paulo Estevão Franco Braga, Henrique Bracarense, Yasmim Caroline Silva, Bruno Ramos Nascimento, Mariângela Carneiro, Francisco Rogerlândio Martins-Melo, Isis Eloah Machado, Pablo Perel, Yvonne Geissbühler, Caroline Demacq, Antônio Luiz Pinho Ribeiro

“…Lifetime direct medical costs represent around 72% of the total lifetime economic burden, while indirect costs, 28%. Annual direct medical costs represent around 11% of the Ministry of Health budget. …”
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The malaria care cascade and factors associated with receiving a malaria test in children under 5 years of age and pregnant women with fever: a cross-sectional household survey fro... by Alexandre Delamou, Heide Weishaar, Charbel El Bcheraoui, Francisco Pozo-Martin, Abdul Karim Mbawah, Hanna-Tina Fischer, Gerrit Burger, Klara Röbl, Lukas Feddern, Brogan Geurts, Habibata Baldé, Ibrahima Kaba, Sara Menelik-Obbarius, Karoline Stein, Vitali Merhi, Macmond M M Kallon, Karim Dumbuya, Josephine Sellu

“…Between 54% and 81% of children and 24% to 69% of pregnant women with malaria received treatment within 2 days of fever-onset by region/district, while delays were reported at all steps of the care cascade. …”
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Attractive targeted sugar baits for malaria control in western Kenya (ATSB-Kenya): enrolment characteristics of cohort children and households by Alice Kamau, Kizito Obiet, Caroline Ogwang, Daniel P. McDermott, Maia Lesosky, Julia Janssen, Wycliffe Odongo, Julie R. Gutman, Jonathan S. Schultz, Wycliffe Nicholas, Brian Seda, Mercy Chepkirui, Frank Aduwo, Oliver Towett, Kephas Otieno, Martin J. Donnelly, Eric Ochomo, Simon Kariuki, Aaron M. Samuels, Feiko O. ter Kuile, Sarah G. Staedke

“…Of these, only 199 (8%) were categorized as ‘improved’, as most houses had open eaves. While 99% of households owned at least one bed net, only 51% were adequately covered (one net per two household residents). …”
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Incidence of PJI in Total Knee Arthroplasty Patients Following Expanded Gram-Negative Antibiotic Prophylactic Protocol by Anzar Sarfraz, Cameron Bussey-Sutton, Emily M. Ronan, Farouk Khury, Joseph A. Bosco, Ran Schwarzkopf, Vinay K. Aggarwal

“…The findings of this study suggest that while EGNAP is safe to use and has minimal nephrotoxic effects, its prophylactic benefits do not extend to the primary TKA population. …”
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Identification and Interpretation of Cultural Landscape Field from the Integral Conservation Perspective by Zhitong LIANG, Yan DU, Haiyan XIA

“…However, current research is still in its infancy and faces dual challenges: ambiguous criteria for integrity definition and insufficient methodologies for revealing intra-systemic relationships. While cultural landscape approaches have gained international traction, their application predominantly focuses on protected areas, rarely addressing critical aspects of integrity assessment, resource selection, or boundary delineation, for which a relational network has yet to be established in the sense of a system. …”
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Health risk perception and behavioral decision-making among online-dating MSM in Shandong, China: perspectives on HIV and new psychoactive substances by Yuyao Chen, Haiying Yu, Xiaoyan Zhu, Ling Li, Lin Wang, Yangji Zhuoma, Na Zhang, Guoyong Wang, Wei Ma, Meizhen Liao

“…Among them, 37.8% (1,052) perceived their risk of HIV infection as low or negligible, while 10.8% (302) believed that using NPS posed little or no harm to their health. …”
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Global Trajectories of Colorectal Cancer Burden From 1990 to 2021 and Projection to 2040 by Xiaolu Chen, Xuesi Dong, Yadi Zheng, Chenran Wang, Zilin Luo, Jiaxin Xie, Zeming Guo, Xiaoyue Shi, Xinyue Zhu, Yongjie Xu, Wei Cao, Fei Wang, Ni Li

“…Higher sociodemographic index, universal health coverage, health expenditure, and gross domestic product per capita were linked to decreasing trends (all p < 0.05). …”
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Profitability and cost-effectiveness analysis of brucellosis control in Armenia: A One Health approach by Uchenna Anyanwu, Artemiy Dimov, Jakob Zinsstag, Fabrizio Tediosi, Tigran Markosyan

“…Control of the disease is currently using the test-and-slaughter strategy, reportedly at a coverage level deemed insufficient to interrupt transmission by the authorities responsible for disease control. …”
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Evaluating ChatGPT and DeepSeek in postdural puncture headache management: a comparative study with international consensus guidelines by Jiayi Deng, Xu Qiu, Chengqi Dong, Li Xu, Xiaoxue Dong, Shiyue Yang, Qinghua Li, Tao Mei, Shi Chen, Yali Wu, Jianliang Sun, Feifang He, Hanbin Wang, Liang Yu

“…Healthcare professionals must exercise caution when using AI tools and should critically evaluate outputs before clinical application. While promising, their partial guideline coverage requires careful human oversight. …”
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A Framework for High-Spatiotemporal-Resolution Soil Moisture Retrieval in China Using Multi-Source Remote Sensing Data by Zhuangzhuang Feng, Xingming Zheng, Xiaofeng Li, Chunmei Wang, Jinfeng Song, Lei Li, Tianhao Guo, Jia Zheng

“…However, SC1 was able to achieve a revisit time of 1–3 days over 60.73% of China’s area in 2021 and 69.36% in 2022, while the area covered by SC2 and SC3 at this revisit time accounted for less than 1% of China’s total area. …”
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A vegetation phenology dataset developed by integrating multiple sources using the reliability ensemble averaging method by Y. Cui, S. Chen, Y. Gong, M. Li, Z. Jia, Y. Zhou, Y. Zhou, Y. H. Fu, Y. H. Fu, Y. H. Fu

“…The new dataset has a spatial resolution of 0.05° and covers the period from 1982 to 2020, with geographic coverage extending above 30° N in the Northern Hemisphere. …”
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