Structural development of the HIV-1 apex-directed PGT145-PGDM1400 antibody lineage by Rosemarie D. Mason, Baoshan Zhang, Nicholas C. Morano, Chen-Hsiang Shen, Krisha McKee, Ashley Heimann, Renguang Du, Alexandra F. Nazzari, Shelby Hodges, Tapan Kanai, Bob C. Lin, Mark K. Louder, Nicole A. Doria-Rose, Tongqing Zhou, Lawrence Shapiro, Mario Roederer, Peter D. Kwong, Jason Gorman

“…Despite similar breadth and potency, the two antibodies differ in their residue-level interactions with important apex features, including N160 glycans and apex cavity, with residue 100i of PGT145 (sulfated tyrosine) penetrating ∼7 Å farther than residue 100i of PGDM1400 (aspartic acid). While apex-directed bNAbs from other donors use maturation pathways that often converge on analogous residue-level recognition, our results demonstrate that divergent residue-level recognition can occur within the same lineage, thereby enabling improved coverage of escape variants.…”
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Bayesian Tapered Narrowband Least Squares for Fractional Cointegration Testing in Panel Data by Oyebayo Ridwan Olaniran, Saidat Fehintola Olaniran, Ali Rashash R. Alzahrani, Nada MohammedSaeed Alharbi, Asma Ahmad Alzahrani

“…Monte Carlo simulations demonstrate that BTNBLS outperforms conventional estimators (OLS, NBLS, TNBLS), achieving minimal bias (0.041–0.256), near-nominal coverage probabilities (0.87–0.94), and robust control of Type 1 errors (0.01–0.07) under high cross-sectional dependence (<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>ρ</mi><mo>=</mo><mn>0.8</mn></mrow></semantics></math></inline-formula>), while the Bayesian Chen–Hurvich test attains near-perfect power (up to 1.00) in finite samples. …”
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Assessment of salt tolerance in peas using machine learning and multi-sensor data by Zehao Liu, Qiyan Jiang, Yishan Ji, Rong Liu, Hongquan Liu, Xiuxiu Ya, Zhenxing Liu, Zhirui Wang, Xiuliang Jin, Tao Yang

“…Structural traits (pH and canopy coverage [CC]), texture features, and spectral data were extracted from these images. …”
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Protektem pikinini blong yu trial: protocol for a single arm field trial to assess the effectiveness of treating-all pregnant women with hepatitis B infection with tenofovir prophy... by Leila Bell, Aleesha Kalulu, Kali Ameara, Nicole Allard, Sereana Natuman, Zeshi Fisher, Caroline SE Homer, Annie Taissets, Kathy Jackson, Navin Karan, Kaylene Kalmos, Emily Deed, Leiwia Dick, Leias Obed, Florita Toa, Harriet Obed, Ben John Taura, Philippe Guyant, Jessica Howell, Jason Iopa, Junior George Pakoa, Minado Paul, Harriet Sam, Tim Spelman, Jenny Stephens, Sale Vurobaravu, Margaret Hellard, Caroline van Gemert

“…Hepatitis B vaccination is available in Vanuatu, but coverage rates for first dose within 24 h of birth and third dose are suboptimal. …”
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A multi-country comparison between mobile phone surveys and face-to-face household surveys to estimate the prevalence of non-communicable diseases behavioural risk factors in low-... by Gulam Muhammed Al Kibria, Saifuddin Ahmed, Dustin G Gibson, Kennedy Lishimpi, Jones K Masiye, Daksha Shah, Melanie Cowan, Wilbroad Mutale, Namasiku Siyumbwa, Julián A Fernández-Niño, Champika Wickramasinghe, Leanne Riley, Stacy Davlin, Rachael Phadnis, Romina Costa Beltrán, Juan Carlos Zevallos Lopez, Juan Vásconez, Hicham El Berri, Samir Mounach, Mangla Gomare, Gulnar Khan, Niraj Dave, Udara Perera

“…MPS sampling frames were generated by random digit dialling, while data collection was done by interactive voice response and SMS. …”
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Access to timely cancer treatment initiation in India: extent, determinants and trendsResearch in context by Pritam Halder, Jyoti Dixit, Nidhi Gupta, Nikita Mehra, Ashish Singh, Pankaj Malhotra, Anisha Mathew, Lalit Kumar, Amal Chandra Kataki, Sudeep Gupta, Shankar Prinja

“…Upon stratifying by enrolment under PMJAY, we found that while the access for timely treatment initiation increased by 33% for those who were not enrolled, vs. 90% among those enrolled under PM-JAY. …”
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Efficacy and safety of a novel short course rifapentine and isoniazid regimen for the preventive treatment of tuberculosis in Chinese silicosis patients: a pilot study (SCRIPT-TB) by Qiao-Ling Ruan, Qing-Luan Yang, Chun-Lian Ma, Miao-Yao Lin, Xi-Tian Huang, Ya-Pin Mao, Ji-Mei Gao, Jin-Ju Li, Xia-Ning Zhang, Zhi-Xiang You, Quan-Qing Zheng, Yan-Fei Ren, Xue-Feng Liu, Ling-Yun Shao, Wen-Hong Zhang

“…Background: Tuberculosis preventive treatment (TPT) is essential for the end TB Strategy, but shorter and better tolerated regimens are needed to boost its coverage and acceptance.Methods: Silicosis patients aged 18 to 65 years received a novel 1H3P3 regimen (400 mg isoniazid and 450 mg rifapentine, thrice-weekly for 4 weeks) under direct observation and were actively followed up for 3 years. …”
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High chromosomal instability is associated with higher 10‐year risks of recurrence for hormone receptor‐positive, human epidermal growth factor receptor 2‐negative breast cancer pa... by Yu‐Yang Liao, Jianfei Fu, Xiang Lu, Ziliang Qian, Yang Yu, Liang Zhu, Jia‐Ni Pan, Pu‐Chun Li, Qiao‐Yan Zhu, Xiaolin Li, Wenyong Sun, Xiao‐Jia Wang, Wen‐Ming Cao

“…Cross‐validation analysis found that high consistency (83.8%) was observed between CIN and MammaPrint score, while only 45% between CIN and Adjuvant! Online score. …”
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Remotely Sensed Comparative Spatiotemporal Analysis of Drought and Wet Periods in Distinct Mediterranean Agroecosystems by Stavros Sakellariou, Nicolas R. Dalezios, Marios Spiliotopoulos, Nikolaos Alpanakis, Ioannis Faraslis, Georgios A. Tziatzios, Pantelis Sidiropoulos, Nicholas Dercas, Alfonso Domínguez, Higinio Martínez López, Francisco Montoya, Ramón López-Urrea, Fadi Karam, Hacib Amami, Radhouan Nsiri

“…The results indicated that Spain and Tunisia (western Mediterranean) exhibit similar patterns over the studied period, while Lebanon demonstrates contrasting trends. Comparing the two extreme dry hydrological years, the Spanish study area faced the highest drought intensity, areal extent and duration (SPI₁₂ = −1.18; −1.84; 28–78%; 9–12 months), followed by the Lebanese (SPI₁₂ = −1.28; −1.39; 37–50%; 7–12 months) and the Tunisian ones (SPI₁₂ = −1.05; −1.08; 10–34%; 8 months). …”
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BONE MARROW ASPIRATION: COST ANALYSIS OVER 12 YEARS IN BRAZIL by RC Venâncio, JISD Gomes, AEO Rego, JEB Silva, PRC Passos, JVC Goes, MFD Nascimento, GM Penha, CCV Costa, EBS Martins

“…In the third four-year period, the total requested was R$213,407.86, while the allocation was R$204,965.23 (96%). Additionally, it was observed that between the first and second four-year periods, there was a reduction in the presented values by R$14,183.92 (6.7%), and approved values fell by R$13,563.13 (6.5%). …”
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Research Progress on CO2 Capture in the Steel Industry Under the Dual Carbon Background by Jing WEI, Min DENG, Dengguo YIN, Long SHI, Zikang QIN, Junfeng ZHENG, Lu YAO, Wenju JIANG, Lin YANG, Zhongde DAI

“…The Japanese COURSE50 project has achieved a 30% reduction in CO2 emissions per ton of crude steel, while BaYi Iron & Steel has upgraded its molten reduction ironmaking furnace to a European smelting furnace, attaining a CO2 capture rate of over 97%. …”
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The prevalence, awareness, and treatment status of diabetic retinopathy among individuals aged 18-75 years in Hubei province in 2019 by Miaoyan SHEN, Lan ZHANG, Shuzhen ZHU, Yumeng TANG, Jingju PAN, Qian LI, Mengge ZHOU, Tianjing HE

“…Multivariable logistic regression analysis showed that poor fasting blood glucose control (>7 mmol/L, Wald χ2=6.563), longer diabetes duration (≥5 years, Wald χ2=22.171), and having hypertension (Wald χ2=5.760) were associated with a higher risk of DR, while having urban employee medical insurance (Wald χ2=4.612) was associated with a lower risk of DR (all P<0.05). …”
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Engaging the private sector as part of HIV pre-exposure prophylaxis service delivery in Vietnam: a comparative analysis of uptake, persistence and HIV seroconversion from 2018 to 2... by Bao Ngoc Vu, Kimberly Green, Huong Phan, Long Tran, Phuong Phan, Tham Tran, Linh Doan, Yen Vu, Chau Pham, Dao Nguyen, Anh Doan, Trang Ngo, Phuong Tran, Vuong Nguyen, Bieu Nguyen, Thai Phan, Ha Nguyen

“…Private-sector PrEP providers play a pivotal role in increasing PrEP uptake and coverage in Vietnam, and will be critical to delivery of new long-acting options.…”
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Utilizing an mHealth Platform and Community Health Workers to Enhance Epilepsy Screening and Treatment in a Rural Setting in Mali: A Closed Cohort Study by Housseini Dolo, Mohamed Kamaforo, Fatoumata dite Nènè Konipo, Oumar Sangho, Mariam Daou, Boubacar Camara, Abdoulaye Konate, Mohamed Sininta, Moussa Sangare, Drissa M. Toure, Hannah C. Fritz, Peter J. Winch, Hamadoun Sangho, Yaya Ibrahim Coulibaly, Youssoufa M. Maiga, Seydou Doumbia

“…This innovative approach resulted in excellent patient outcomes, including a high retention rate over the follow-up period and statistically significant reduction in seizures. While challenges such as mobile network coverage and varying literacy levels among Relais were encountered, the findings strongly support this mHealth strategy as a viable solution to bridge the healthcare gap, significantly improving access to and management of epilepsy for remote and hard-to-reach populations.…”
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Prevalence of Plasmodium spp. in humans and cattle: Implications for zoonotic malaria transmission in Indonesia by Hamzah Hasyim, Babucarr Jassey, Ririh Yudhastuti, Misnaniarti Misnaniarti, Iche Andriyani Liberty, Elvi Sunarsih, Langgeng Priyanto, Dalilah Dalilah, Yusri Yusri, Fadhilah Eka Maharani, Lukman Hakim, Siti Herlinda, Fildzah Hashifah Taufiq

“…The absence of infections in humans suggests the effectiveness of current public health measures, while the presence of Plasmodium DNA in cattle underscores the potential role of cattle as parasite reservoirs. …”
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Biases and complementarity in gut viromes obtained from bulk and virus-like particle-enriched metagenomic sequencing by Yun Li, Chuqing Sun, Jiaying Zhu, Mingyan Geng, Min Li, Xing-Ming Zhao, Wei-Hua Chen

“…Nevertheless, bulk sequencing can suffer from lower coverage, leading to fragmented sequences and potentially missing some viral species. …”
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High-throughput method for improving rice AGB estimation based on UAV multi-source remote sensing image feature fusion and ensemble learning by Jinpeng Li, Jinpeng Li, Jinxuan Li, Jinxuan Li, Dongxue Zhao, Dongxue Zhao, Qiang Cao, Qiang Cao, Fenghua Yu, Fenghua Yu, Fenghua Yu, Yingli Cao, Yingli Cao, Yingli Cao, Shuai Feng, Shuai Feng, Shuai Feng, Tongyu Xu, Tongyu Xu, Tongyu Xu

“…However, vegetation indices (VIs) often suffer from saturation due to high canopy coverage and vertical organs, limiting their accuracy across multiple growth stages. …”
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Seasonal water level changes affect plant diversity and littoral widths at different elevation zones in the Erhai Lake by Feng Zhu, Feng Zhu, Feng Zhu, Jing Yuan, Jing Yuan, Zeying Hou, Zeying Hou, Xia Guo, Xia Guo, Wanxue Liao, Wanxue Liao, Shenglin Yang, Shenglin Yang, Shenglin Yang, Zhaosheng Chu, Zhaosheng Chu, Zhaosheng Chu

“…The results revealed that species with monotonically increasing distributions had the widest niche breadths, followed by symmetric unimodal species, while monotonically decreasing species exhibited the narrowest. …”
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Analisis Dukungan Petugas Kesehatan Dalam Optimalisasi Competence Baby Care Pada Ibu muda Melalui Pendekatan Maternal Sensitivity Models Berbasis Keluarga (Analysis of Health Of... by diyan indriyani

“…The data were collectedusing Focus Group Discussion (FGD) and indept interview on health officials in both public health centers of Sumbersari and Sukorambi Jember with 9 participants, while the number of respondents who became the subject of this research were 50 families. …”
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EGFL7 enhances surface expression of integrin α5β1 to promote angiogenesis in malignant brain tumors by Nevenka Dudvarski Stanković, Frank Bicker, Stefanie Keller, David TW Jones, Patrick N Harter, Arne Kienzle, Clarissa Gillmann, Philipp Arnold, Anna Golebiewska, Olivier Keunen, Alf Giese, Andreas von Deimling, Tobias Bäuerle, Simone P Niclou, Michel Mittelbronn, Weilan Ye, Stefan M Pfister, Mirko HH Schmidt

“…We found that the encoded extracellular matrix protein epidermal growth factor‐like protein 7 (EGFL7) was secreted by glioma blood vessels but not glioma cells themselves, while no major role could be assigned to the parasitic miRNAs miR‐126/126*. …”
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