Harnessing defective interfering particles and lipid nanoparticles for effective delivery of an anti-dengue virus RNA therapy by Min-Hsuan Lin, Pramila Maniam, Dongsheng Li, Bing Tang, Cameron R. Bishop, Andreas Suhrbier, Lucy Wales- Earl, Yaman Tayyar, Nigel A.J. McMillan, Li Li, David Harrich

“…DENV vaccine efficacy varies depending on the vaccine type, the circulating serotype, and vaccine coverage. We investigated defective interfering particles (DIPs) and lipid nanoparticles (LNPs) to deliver DI290, an anti-DENV DI RNA. …”
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Determinants of non-testing for HIV among women during antenatal care follow up in sub-saharan Africa: a hierarchical analysis of recent Demographic and Health Survey datasets by Tadesse Tarik Tamir, Alebachew Ferede Zegeye, Enyew Getaneh Mekonen, Bikis Liyew, Belayneh Shetie Workneh

“…At the community level, low media exposure and high illiteracy rates were significant, while at the country level, high fertility rates and low literacy rates were also associated with lower rates of HIV testing during antenatal care. …”
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Overall compilation of adverse effects of non-steroidal anti-inflammatory drugs: a hypothesis-free systematic investigation using a nationwide cohort study by Hyein Han, Du Hyun Ro, Du Hyun Ro, Du Hyun Ro, Du Hyun Ro, Hyuk-Soo Han, Hyuk-Soo Han, Sungho Won, Sungho Won, Sungho Won, Sungho Won

“…They also contribute to better diagnosis and management of AEs while providing valuable guidelines for both patients and clinicians.…”
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Alternative therapeutic approaches for combating multi-drug-resistant bacteria: Reverse vaccinology against Enterobacter cloacae by Gabriela Guerrera Soares, Marcelo Silva Folhas Damas, Pedro Mendes Laprega, Rebecca Elizabeth Shilling, Eduarda Oliva Ribeiro Rangel, Louise Teixeira Cerdeira, Murillo Rodrigo Petrucelli Homem, André Pitondo-Silva, Andrea Soares da Costa-Fuentes, Maria-Cristina da Silva Pranchevicius

“…They were all processed and presented through the MHC class pathway, while also showing high population coverage. VEC1 showed the most consistent performance, with the highest average binding affinity (−24.07 kcal/mol), docking score (−322.21), and the most favorable dissociation constant at 37 °C. …”
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Adherence to Attendance at Outpatient Clinic and Longterm Survival of Patients after Stroke in Outpatient Setting: the Data of REGION-M Registry by S. Yu. Martsevich, S. N. Tolpygina, M. I. Chernysheva, A. V. Zagrebelny, V. P. Voronina, M. M. Lukyanov, N. P. Kutishenko, N. A. Dmitrieva, O. V. Lerman, Yu. V. Lukina, S. V. Blagodatskikh, E. Yu. Okshina, N. E. Parsadanyan

“…At the same time, there is a reserve in improving the long-term prognosis of the lives of patients who have suffered a cerebral stroke or transient ischemic attack, due to greater coverage of patients with medical supervision in the clinic.…”
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Seroprevalence against SARS-CoV-2 after booster vaccination in a prison in Alicante (Spain) by Ana C. Montagud, Raul Moragues, Nancy Vicente-Alcalde, Nancy Vicente-Alcalde, Emilia Montagud, José Antonio Hurtado-Sánchez, José Antonio Hurtado-Sánchez, José Tuells, José Tuells

“…The staff received more booster doses and obtained a better response to seropositivity, with 72.5% of anti-SARS-CoV-2 result positive while prisoners reached 56.3%.ConclusionThe COVID-19 vaccination status within the prison community following the initiation of primary immunization and subsequent booster doses, shows a low immunization coverage (60.9%), which is below expectations given the immunization strategies implemented since the start of the pandemic. …”
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Soil organic carbon estimation using spaceborne hyperspectral composites on a large scale by Xiangyu Zhao, Zhitong Xiong, Paul Karlshöfer, Nikolaos Tziolas, Martin Wiesmeier, Uta Heiden, Xiao Xiang Zhu

“…The SOC maps indicate that water-associated areas, such as coastal soils and bogs, tend to have higher SOC, while mountain areas tend to contain lower SOC. Such findings align with SOC distribution across soil types and show the effectiveness of the model.…”
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Performance of RIS-Secured Short-Packet NOMA Systems With Discrete Phase-Shifter to Protect Digital Content and Copyright Against Untrusted User by Nguyen Quang Sang, Hye-Young Kim, Tan N. Nguyen, Minh Bui Vu, Phuong T. Tran, Tran Trung Duy, Byung-Seo Kim, Miroslav Voznak

“…In this strategy, untrustworthy users will be allocated higher power levels than trustworthy users, while the latter will be configured with sub-optimal phase shift criteria at RIS to maximize its cascaded channel gain. …”
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Acceptability of the R21/Matrix-M malaria vaccine alongside existing malaria interventions in the trial context by Jayne Webster, Brian Greenwood, Daniel Chandramohan, Alassane Dicko, Issaka Sagara, Djibrilla Issiaka, Adrian VS Hill, Halimatou Diawara, Fatoumata Koita, Seydou Traoré, Jane Grant, Mehreen Datoo, Mala Sylla, Abdrahmane Boncane Dicko

“…Implementation research is needed to evaluate and ensure co-coverage of complementary malaria control interventions, including SMC in seasonal settings, in the face of the scale-up of R21/Matrix-M and other malaria vaccines.…”
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Landscape characteristics influencing habitat use of grassland birds in the Pampas ecoregion of Argentina by Clara Trofino-Falasco, María G. Pizzarello, María V Simoy, María F. Aranguren, Rosana E. Cepeda, Adrián S Di Giacomo, Claudia B. Marinelli, Gaston Moran, Maria C. Neyra, David G. Vera, Igor Berkunsky

“…Granivores and omnivores used sites with greater perennial pasture coverage, while insectivores and also granivores used sites near groves and away from streams. …”
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Knowledge, attitude and practices regarding Hepatitis B vaccination among students of a government medical college in Mumbai by Subhana Siyad, Kamran Qureshi, Deepika Bishnoi, Smita Chavhan, Akanksha Singh

“…It emphasized the need for institutional support, funding, and research to improve vaccination rates. While the study has strengths, such as its relevance and potential impact, limitations include reliance on self-reported data, a cross-sectional design, and limited generalizability. …”
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Long-term hydro-economic analysis tool for evaluating global groundwater cost and supply: Superwell v1.1 by H. Niazi, S. B. Ferencz, N. T. Graham, J. Yoon, T. B. Wild, M. Hejazi, D. J. Watson, C. R. Vernon

“…The supply–cost curves produced by the model show that most (90 %) nonrenewable groundwater in storage globally is extractable at costs lower than USD 0.57 m<span class="inline-formula">⁻³</span>, while half of the volume remains extractable at under USD 0.108 m<span class="inline-formula">⁻³</span>. …”
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Prevalence and determinants of cervical cancer screening among women aged 15–49 years in Tanzania: analysis of demographic and health survey 2022 by Gladys Reuben Mahiti, Jovinary Adam, Pankras Luoga

“…The dependent variable was CCS status, while independent variables included demographic characteristics, socio-economic factors, and health system factors. …”
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Vaccination status and its determinants among children aged 12-23 months in Tigray, northern Ethiopia: A zero-inflated Poisson regression analysis. by Hailay Gebretnsae, Brhane Ayele, Fana Gebresilassie, Tsegay Hadgu, Hayelom Kahsay, Asfawosen Aregay, Kiros Demoz, Mulugeta Tilahun, Ataklti Gebretsadik, Znabu Hadush, Liya Mamo, Tsegay Wellay, Reda Shamie, Adhena Ayaliew Werkneh, Mebrahtu Kalayu, Assefa Ayallew, Ferehiwot Hailemariam, Abrham Gebrelibanos, Tadele Tesfean, Haben Haileselassie, Mohammedtahir Yahya, Melaku Abraha, Haftu Gebrehiwot, Desalegn Meresa, Gebrekiros Gebremichael Meles, Atakilti Fisseha, Yaynshet Gebreyohannes, Moges Mekonnen, Ashenafi Asmelash, Teame Zegeye, Mitswat Mulaw, Tesfu Alemu, Gebrehaweria Gebrekurstos, Rieye Esayas, Tsegay Berihu, Amanuel Haile, Araya Abrha Medhanyie, Mussie Alemayehu, Afework Mulugeta

“…The overall proportion of fully vaccination was 59.9% (95% Confidence Interval (CI): 57.7-62.3%), while 29.4% (95% CI: 27.1-31.7%) were under-vaccinated and 10.7% (95% CI: 9.1-12.2%) were zero-dose. …”
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Early essential newborn care is associated with improved newborn outcomes following caesarean section births in a tertiary hospital in Da Nang, Vietnam: a pre/post-intervention stu... by Zhao Li, Howard Lawrence Sobel, Priya Mannava, John Charles Scott Murray, Hoang Thi Tran, Le Thi Huynh, Phuong Thi Thu Nguyen, Hoang Thi Nam Giang, Tuyen Thi Mong Le, Tuan Anh Hoang, Vinh Duc Nguyen, Nga Thi Quynh Pham

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LevelWAN: a cost-effective, open-source IoT system for water level monitoring in highly dynamic aquatic environments by Ilane Cherif, Frédéric Cherqui, Franck Perret, Bastien Bourjaillat, Lionel Lord, Jean-Luc Bertrand-Krajewski, Nicolas Walcker, Maria Gisi, Laëtitia Bacot, Oldrich Navratil

“…The deployment of low-cost network sensors (LCNS) for environmental monitoring has become increasingly prevalent in recent years, offering a cost-effective solution for enhancing spatial sensor coverage while minimizing financial constraints. This study presents LevelWAN, a water level monitoring system specifically designed for highly dynamic aquatic environments such as rivers, ponds or lakes. …”
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The impact of participation status on the colorectal cancer incidence, stage and survival outcomes in the Shanghai colorectal cancer screening program by PENG Peng, DOU Jianming, WU Chunxiao, PANG Yi, GONG Yangming, WU Mengyin, SHI Yan, GU Kai

“…The 5-year relative survival rate of the screening group was 73.94%, while the non-screening group was 59.66%. The survival rate indicators of the former were significantly higher than those of the latter, and the difference was statistically significant. …”
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Synergistic effect of photobiomodulation and leukocyte-platelet rich fibrin on bone regeneration in rat critical defects by Ali Sadeghian, Bita Rohani, Sadegh Hasannia, Fatemeh Mashhadiabbas, Reza Fekrazad

“…Connective tissue analysis revealed that BL and BLP groups had 81.8% loose connective tissue, while the Control group had 91.7% loose connective tissue and 8.3% fibrosis. …”
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Dosimetric Comparison of Noncoplanar VMAT Without Rotating the Patient Couch Versus Conventional Coplanar/Noncoplanar VMAT for Head and Neck Cancer: First Report of Dynamic Swing A... by Kouta Hirotaki, MS, Kento Tomizawa, MD, PhD, Satoe Kitou, BS, Shunta Jinno, MS, Shunsuke Moriya, PhD, Takeshi Fujisawa, MD, Sadamoto Zenda, MD, PhD, Takeji Sakae, PhD, Masashi Ito, BS

“…Conclusions: DSA plans using OXRAY for HNSCC maintained PTV coverage while reducing parotid gland and oral cavity mean doses compared to coplanar VMAT plans, although delivery times increased. …”
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Revolutionising young adult diabetes care: a patient-centred transformation to improve access, engagement and outcomes in one of England's most deprived areas by Tala Balafshan, Heather Sullivan, Suzanne Keigan, Amanda Wilson, Ifeoluwa Oyedeji

“…Eight of nine care processes exceeded national benchmarks, including 89.6% coverage for retinal screening and 80% for blood pressure monitoring. • Mental health integration3: CORE 10 screening, conducted every 4 months, identified 28% of patients with moderate to severe mental health concerns, enabling timely psychological referrals. • Enhancing patient engagement: pre-clinic questionnaires empowered patients to guide consultations, personalising care. …”
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