Mitochondrial haplogroup M contributes to asthma risk in the Kuwaiti population by Mohammed Dashti, Hussain Bahbahani, Hussain Alsaleh, Thangavel Alphonse Thanaraj, Fahd Al-Mulla

“…In Kuwait, the prevalence of asthma among young adults is approximately 11%, with a strong maternal influence on asthma risk. While nuclear genetic studies have identified several asthma-associated loci, the role of maternally inherited mitochondrial DNA (mtDNA) in asthma susceptibility remains poorly understood, particularly in Middle Eastern populations.MethodsIn this exploratory study, we analysed mtDNA from 287 Kuwaiti individuals, including 48 asthmatics and 239 controls, extracted from whole-exome sequencing data (average coverage 27×), with variant calling via GATK and haplogroup assignment using HaploGrep2. …”
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Making a Difference from Day One: The Urgent Need for Universal Neonatal Hearing Screening by Michail Athanasopoulos, Pinelopi Samara, Georgios Batsaouras, Ioannis Athanasopoulos

“…Countries like the United States and Australia have successfully implemented NHS, leading to earlier diagnoses, improved language development, and better educational outcomes. In Europe, while many nations have adopted NHS, consistency remains a challenge. …”
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Extent of Integration of Priority Interventions into General Health Systems: A Case Study of Neglected Tropical Diseases Programme in the Western Region of Ghana. by Ernest O Mensah, Moses K Aikins, Margaret Gyapong, Francis Anto, Moses J Bockarie, John O Gyapong

“…Service delivery was most integrated while financing and planning were least integrated. …”
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From ferromagnetic semiconductor to antiferromagnetic metal in epitaxial Cr x Te y monolayers by Naina Kushwaha, Olivia Armitage, Brendan Edwards, Liam Trzaska, Jennifer Rigden, Peter Bencok, Deepnarayan Biswas, Tien-Lin Lee, Charlotte Sanders, Gerrit van der Laan, Peter Wahl, Phil D. C. King, Akhil Rajan

“…We find, however, that monolayer CrTe2 forms as an antiferromagnetic metal, while monolayer Cr2+ε Te3 hosts an intrinsic ferromagnetic semiconducting state. …”
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Advancing the Fight Against Cervical Cancer: The Promise of Therapeutic HPV Vaccines by Qian Zheng, Misi He, Zejia Mao, Yue Huang, Xiuying Li, Ling Long, Mingfang Guo, Dongling Zou

“…Human papillomavirus (HPV) is a major global health issue and is recognized as the leading cause of cervical cancer. While prophylactic vaccination programs have led to substantial reductions in both HPV infection rates and cervical cancer incidence, considerable burdens of HPV-related diseases persist, particularly in developing countries with inadequate vaccine coverage and uptake. …”
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Trade-offs and synergistic evolution of ecosystem services and land use driving mechanisms in karst ecologically vulnerable areas of China by Dan Zhang, Zhongfa Zhou, Lu Zhang, Quan Chen, Dan Luo, Denghong Huang, Qing Feng, Changli Zhu

“…ES synergies were enhanced through optimized land use restructuring via increased forest/grassland coverage from ecological projects.…”
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Ten years of tropospheric ozone from DSCOVR EPIC: science and applications by Jerry R. Ziemke, Jerry R. Ziemke, Natalya A. Kramarova, Stacey M. Frith, Stacey M. Frith, Kai-Liang Huang, Kai-Liang Huang, Kanghyun Baek, Kanghyun Baek, Jay R. Herman, Jay R. Herman

“…No current satellite instruments other than EPIC make measurements every 1–2 h over the sunlit disk of the Earth while still obtaining near-global coverage each day. …”
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Exploring disparities in satisfaction with obstetric-gynecological care among insured and uninsured women in Almaty, Kazakhstan: a comparative cross-sectional study by Sholpan Aliyeva, Sholpan Aliyeva, Vyacheslav Lokshin, Maksut Kamaliev, Sholpan Sarmuldayeva, Gani Kaldybayev, Oxana Tsigengagel

“…The observed “satisfaction paradox” highlights that policy must adopt a dual focus: promoting enrolment while simultaneously improving the quality of patient-provider interactions to meet the higher expectations of insured patients.…”
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Letermovir use for cytomegalovirus prophylaxis following lung transplantation: A single-center review by Alyssa K. Mezochow, MD, MSc, Kevin D. He, MD, Kathryn Whitaker, MD, Emily Blumberg, MD, Maria M. Crespo, MD, Andrew Courtwright, MD, PhD

“…Results: Over the study period, 88 LTRs were prescribed letermovir with most (93%) switching due to myelosuppression while on valganciclovir. Of those prescribed letermovir, 67 (76%) actually started letermovir, with the primary barrier being insufficient insurance coverage or high copay cost. …”
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An Intelligent Field Monitoring System Based on Enhanced YOLO-RMD Architecture for Real-Time Rice Pest Detection and Management by Jiangdong Yin, Jun Zhu, Gang Chen, Lihua Jiang, Huanhuan Zhan, Haidong Deng, Yongbing Long, Yubin Lan, Binfang Wu, Haitao Xu

“…Addressing critical challenges in real-time detection accuracy and environmental adaptability, the proposed system integrates three innovative components: (1) a novel Receptive Field Attention Convolution module enhancing feature extraction in complex backgrounds; (2) a Mixed Local Channel Attention module balances local and global features to improve detection precision for small targets in dense foliage; (3) an enhanced multi-scale detection architecture incorporating Dynamic Head with an additional detection head, enabling simultaneous improvement in multi-scale pest detection capability and coverage. The experimental results demonstrate a 3% accuracy improvement over YOLOv8n, achieving 98.2% mean Average Precision at 50% across seven common rice pests while maintaining real-time processing capabilities. …”
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Effects of direction and gender on lower limb biomechanics during forward lunges in badminton players: a preliminary analysis by Li Huang, Yan Zhang, Shunxiang Gao, Junxia Lin, Fei Zheng, Yaodong Gu

“…While previous studies have examined the influence of lunge direction on lower limb biomechanics, the effects of gender have yet to be explored. …”
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Private sector quality interventions to improve maternal and newborn health in low- and middle-income countries: a scoping review by Anne-Sophie Jung, Nuhu Yaqub, Samantha R. Lattof, Joe Strong, Blerta Maliqi

“…Findings are presented as a systematic narrative synthesis using the WHO’s National Quality Policy and Strategy (NQPS) framework’s quality intervention groups. While various interventions exist, public–private partnership (PPP) schemes and vertical programmes have received more scholarly attention. …”
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Biomechanical Analysis of Pediatric Dental Crowns: A Comparative Study of Zirconia, Bioflex, and PEEK Using Finite Element Analysis by Leena Kumari, Aradhana Agrawal, Anusmita Mandal, Divyani Nandekar, Jagruti Narlawar, Shilpa Ghosh

“…Restorative approaches, including full-coverage crowns, are commonly used to preserve primary teeth, with zirconia crowns being the preferred choice for durability and aesthetics. …”
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Single cell metabolic phenome and genome via the ramanome technology platform: Precision medicine of infectious diseases at the ultimate precision? by Jian Xu, Jianzhong Zhang, Yingchun Xu, Yi‐Wei Tang, Bo Ma, Yuzhang Wu

“…Moreover, to source track a cell, Raman‐activated cell sorting followed by sequencing or cultivation proceeds, producinging an indexed, high coverage genome assembly or a pure culture from precisely one pathogenic cell. …”
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Enhancing Functional Properties and Mold Resistance of Gypsum Plasters with Caffeine by Klára Kobetičová, Jitka Krejsová, Martin Keppert, Vojtěch Pommer, Ivana Burianová, Martin Böhm, Robert Černý

“…The plasters directly mixed with caffeine were about 72% less attacked by molds than the control, while immersed samples showed only a 20% reduction in mold coverage. …”
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Study on the rainfall erosion resistance of xanthan gum- guar gum ecological substrates by Juan Wan, Yunlong Jia, Henglin Xiao, Shaoping Huang, Zhonggeng Tang

“…It analyses the effects of different types and dosages of gums on plant germination rates and projected coverage, determining the optimal dosage for each gum. …”
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Building an integrated healthcare system of China: an assessment of coupling coordination between disease prevention, medical services, and healthcare financing from 2012 to 2021 by Guowu Huang, Wanying Wu, Qiaoxi Wen, Liyong Lu, Jay Pan

“…Abstract Background Universal Health Coverage (UHC) is a central component of the Sustainable Development Goals, and integrated healthcare is recognized as a key pathway to achieving UHC. …”
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Development and validation of Mental Health Literacy Assessment Scale among community health workers in Nepal by Shishir Paudel, Anisha Chalise, Prashabdhi Shakya, Tulsi Ram Bhandari

“…While these findings support its utility in this context, further validation is needed to establish its applicability across other low- and middle-income countries to assess its effectiveness in diverse cultural and geographic settings.…”
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Expert consensus and recommendations on the live attenuated hepatitis A vaccine and immunization practices in India by Nitin Shah, M.M.A. Faridi, Sheila Bhave, Apurba Ghosh, S. Balasubramanian, Vidya Arankalle, Raju Shah, Amar Jeet Chitkara, Arun Wadhwa, Jaydeep Chaudhry, Ramesh Srinivasan, M. Surendranath, Amita Sapru, Monjori Mitra

“…While Hepatitis A Virus (HAV) vaccination in global immunization programs has shown a virtual elimination of the disease within few years of the vaccination program, changing epidemiological landscape in India underscores the need for evidence-based, updated guidance on immunization practices. …”
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NanoAbLLaMA: construction of nanobody libraries with protein large language models by Xin Wang, Haotian Chen, Bo Chen, Lixin Liang, Fengcheng Mei, Bingding Huang

“…Statistical analysis of CDR regions confirmed diversity, particularly in CDR3, enabling the creation of synthetic libraries with high humanization (>99.9%) and low risk.DiscussionThis work establishes a paradigm shift in nanobody library construction by integrating LLMs, significantly reducing time and resource demands. While NanoAbLLaMA excels in germline-specific generation, limitations include restricted germline coverage and framework flexibility. …”
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