Case report: JAK inhibitor treatment of immune dysregulation symptoms in a patient with PTPN2 deficiency by Anna Roppelt, Ulyana Markina, Irina Beloglazova, Irina Beloglazova, Vasily Parshin, Dmitry Kanner, Dmitry Pershin, Mariia Fadeeva, Elena Raykina, Maxim Aleksenko, Alexander Karaulov, Mariana Lysenko, Mariana Lysenko, Daria Fomina, Daria Fomina, Daria Fomina

“…At the 9- and 16-month checkpoint, after 6 and 13 months correspondingly of monotherapy with ruxolitinib at a dosage of 30 mg per day, the patient had stable blood counts, lymphadenopathy decreased, and the lung interstitial disease improved. …”
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Oxidative and Excitatory Neurotoxic Stresses in CRISPR/Cas9-Induced Kynurenine Aminotransferase Knockout Mice: A Novel Model for Despair-Based Depression and Post-Traumatic Stress... by Ágnes Szabó, Zsolt Galla, Eleonóra Spekker, Mónika Szűcs, Diána Martos, Keiko Takeda, Kinuyo Ozaki, Hiromi Inoue, Sayo Yamamoto, József Toldi, Etsuro Ono, László Vécsei, Masaru Tanaka

“…Little is known about the consequences of deleting the KYN enzyme gene. …”
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Haematobiochemical alterations and lesion characterization induced by haemonchosis in slaughtered sheep at Gondar ELFORA abattoir, Ethiopia by Birhan Anagaw Malede, Mersha Chanie Kebede, Asnakew Mulaw Berihun, Muluken Yayeh Mekonnen, Mohammed Yesuf, Tadegegn Mitiku, Mastewal Birhan, Ambaye Kenubih, Abraham Belete Temesgen

“…Due to hypoproteinemia observed, it is advisable to supplement helminth-infected animals with protein-rich feeds, such as legumes.…”
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Surgical Outcomes and Associated Morbidity of Active and Expectant Management of Second-Trimester Placenta Accreta Spectrum (PAS) by Jessian L. Munoz, Rachel Counts, Amanda E. Lacue, Kayla E. Ireland, Patrick S. Ramsey, Kristyn Brandi

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Analysis of clinical characteristics and risk factors for patients with heat stroke in western China in 2022: a multicenter retrospective study by Xin Zheng, Yuchun Gao, Qinli Xie, Qiulan Chen, Chuan Guo, Qionglan Dong, Jin Tang, Jun Luo, Ying Ge, Jian He, Xiaolin Hou, Guanghong Zhou, Yuan Chen, Haiquan Cao, Jiujia Xiao, An Lan, Qiu Chen, Yonghong Zeng, Jing Huang, Huaicong Long

“…HS patients with high blood cell counts, impaired coagulation, liver and kidney diseases, and those with a specific type of CHS may face a poor prognosis. …”
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Burden of chronic obstructive pulmonary disease in adults aged 70 years and older, 1990-2021: Findings from the Global Burden of Disease Study 2021. by Kaifang Meng, Xu Chen, Zhishang Chen, Jing Xu

“…Although the death and DALY rates attributed to COPD have globally decreased in older adults, the absolute counts are rapidly increasing. The inequalities across different regions and countries underscore a multi-faceted approach to COPD management in older adults.…”
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Factors affecting the design of the management dashboard framework with an emphasis on the components of human resources productivity by Hassan Barmaki, Farshad Faezy Razi, Ehtesham Rashidi

“…Personal or career development is an ongoing process of assessing the educational needs of each individual and planning to meet these needs. This process helps employees to reflect on their knowledge, performance or success; and to plan their personal and educational development.…”
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Effect of miR-144-3p-Targeted Regulation of PTEN on Proliferation, Apoptosis, and Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells under Stretch by Shiyong Ling, Xi Luo, Bo Lv, Hua Wang, Mengzhi Xie, Kai Huang, Jingchuan Sun

“…To investigate the effects of miR-144-3p-targeted regulation of phosphatase and tensin homolog deleted on chromosome ten (PTEN) gene on proliferation, apoptosis, and osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) under retraction force. …”
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AN INTEGRATED INFORMATION SYSTEM ON BIORESOURCE COLLECTIONS OF THE FASO OF RUSSIA by S. A. Lashin, D. A. Afonnikov, M. A. Genaev, F. V. Kazantsev, E. G. Komyshev, E. A. Oschepkova, А. V. Petrov, D. A. Rasskazov, A. A. Smirnova, N. A. Kolchanov

“…Collection materials have generally been formed over hundreds of years and may describe a vast number of samples counted by billions. Great efforts are made to preserve these materials, as well as to obtain more and more samples. …”
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