Analysis of the effect of initial hemostasis resuscitation with recombinant human coagulation factor VII a on the treatment of postoperative hemorrhage in cardiac surgery by Yan Yu, Maomao Liu, Xuran Lu, Li Yu, Nan Liu

“…Abstract Objective To investigate the effectiveness of initial hemostatic resuscitation(IHR) on the treatment of bleeding with recombinant human coagulation factor VIIa after cardiac surgery. …”
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Intramural pregnancy after intrauterine insemination in a nulligravid patient without previous uterine trauma, complicated by idiopathic thrombocytopenic purpura: A case report by Koyo Yamamoto, Tsuyoshi Takiuchi, Kengo Kiso, Saki Ishii, Satoshi Nakagawa, Yasuto Kinose, Michiko Kodama, Yutaka Ueda, Kenjiro Sawada, Takahiro Tsuboyama, Tadashi Kimura

“…Early diagnosis and appropriate management of IMP are critical to prevent severe intraperitoneal bleeding, while preserving future fertility.…”
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Case report: Successful treatment of hyperbaric oxygen for radiation-induced hemorrhagic cystitis in a 95-year-old patient with bladder cancer by Li Lin, Li Lin, Man He, Yanyan Zeng, Xiaoxiao Ni, Yequn Guo, Xiaojuan Xie, Lingling Sun, Huai Huang

“…After the 196th HBOT, pelvic MRI revealed a reduction in the size of the lesion on the left posterior wall of the bladder compared to prior assessments. …”
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Impact of antiplatelet therapy on hemostatic plug formation in the setting of thrombocytopenia by Robert H. Lee, Abigail Ballard-Kordeliski, Summer R. Jones, Wolfgang Bergmeier

“…Results: In the saphenous vein laser injury model, neither single nor dual APT significantly increased bleeding compared with vehicle at platelet counts >2 × 108/mL. …”
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Immune thrombocytopenia in infants: a retrospective study with comparison to toddlers by Anselm Chi-wai Lee

“…Besides age, the sex ratio, severity of bleeding, platelet counts and proportion that required treatment were comparable between infants and toddlers. …”
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Editorial – Revista Ambiente Contábil – Volume 17 – Número 1 – Ano 2025 (Jan./Jun. 2025) by Prof. Dr. Maurício Corrêa da Silva

“…The general objective of the article is to analyze whether the electoral accountability of mayoral candidates during the 2020 Amazonian municipal elections promotes transparency in campaign financing and to compare financing with re-election in the electoral contest. …”
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Darunnajah Vote System Application Design Using PHP Programming Language by Supriadi Panggabean, Wahyu Joko Saputro, Faishal Wafiq Zakiy, Tutik Lestari, Ahmad Rifqi

“…Voting is the most important part of choosing leaders in an organization or institution, especially for those of us who use a democratic system. The election of organizational leaders in Darunnajah is still carried out conventionally, elections still use paper to select organizational leaders which is carried out by recording and counting the name or picture of one of the candidates. …”
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Argonaute2 modulates megakaryocyte development and sex-specific control of platelet protein expression and reactivity by Sophia Lazar, Jeremy G.T. Wurtzel, Shayan Askari, Matthew Cooper, Xuefei Zhao, Peisong Ma, Lawrence E. Goldfinger

“…We generated megakaryocyte/platelet-specific Ago2-deleted (Ago2 KO) mice and assessed proteomic and functional effects. …”
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SAFETY OF BRONCHOALVEOLAR LAVAGE IN HEMATOLOGICAL PATIENTS WITH THROMBOCYTOPENIA – A RETROSPECTIVE COHORT STUDY by Ivan GUR, Roei Tounek, Yaniv Dotan, Elite Vainer Evgrafov, Stav Rakedzon, Eyal Fuchs

“…Any other bleeding were recorded as secondary outcomes.    …”
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Spontaneous Hemopericardium Leading to Cardiac Tamponade in a Patient with Essential Thrombocythemia by Anand Deshmukh, Shanmuga P. Subbiah, Sakshi Malhotra, Pooja Deshmukh, Suman Pasupuleti, Syed Mohiuddin

“…ET is characterized by elevated platelet counts that can lead to thrombosis but paradoxically it can also lead to a bleeding diathesis. …”
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Current Status for Gastrointestinal Nematode Diagnosis in Small Ruminants: Where Are We and Where Are We Going? by Sarah Jane Margaret Preston, Mark Sandeman, Jorge Gonzalez, David Piedrafita

“…This review describes much of the research investigated to date to improve the current diagnostic for the above practices which is based on counting the number of parasite eggs in faeces.…”
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Diagnosis and clinical management of hepatosplenic schistosomiasis: A scoping review of the literature. by Francesca Tamarozzi, Veronica A Fittipaldo, Hans Martin Orth, Joachim Richter, Dora Buonfrate, Niccolò Riccardi, Federico G Gobbi

“…The most common diagnostic approaches to stratify patients based on the risk of variceal bleeding included the use of ultrasonography and platelet counts; on the contrary, evaluation and use of noninvasive tools to guide the choice of therapeutic interventions are lacking. …”
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Matrix Metalloproteinase-9 Production following Cardiopulmonary Bypass Was Not Associated with Pulmonary Dysfunction after Cardiac Surgery by Tso-Chou Lin, Feng-Yen Lin, Yi-Wen Lin, Che-Hao Hsu, Go-Shine Huang, Zhi-Fu Wu, Yi-Ting Tsai, Chih-Yuan Lin, Chi-Yuan Li, Chien-Sung Tsai

“…Thirty patients undergoing elective cardiac surgery were included. Arterial blood was sampled at 6 sequential points (before anesthesia induction, before CPB and at 2, 4, 6, and 24 h after beginning CPB) for plasma MMP-9 concentrations by ELISA. …”
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Neutrophils Are Dysregulated in Patients with Hereditary Angioedema Types I and II in a Symptom-Free Period by Tereza Grymova, Marcela Vlkova, Premysl Soucek, Roman Hakl, Jana Nechvatalova, Peter Slanina, Julie Stichova, Jiri Litzman, Tomas Freiberger

“…In summary, the results showed neutrophils’ alerted state and dysregulation at the transcript level in patients with HAE types I and II even in a symptom-free period, which might make them more susceptible to edema formation. …”
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Extracting Regular Building Footprints Using Projection Histogram Method from UAV-Based 3D Models by Yaoyao Ren, Xing Li, Fangyuqing Jin, Chunmei Li, Wei Liu, Erzhu Li, Lianpeng Zhang

“…Utilizing the projection histogram method, these facets are grouped and processed to extract regular building footprints. …”
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Impact of Thrombopoietin Receptor Agonists on Pathophysiology of Pediatric Immune Thrombocytopenia by Paschalis Evangelidis, Konstantinos Tragiannidis, Eleni Gavriilaki, Athanasios Tragiannidis

“…ITP is commonly manifested with skin and mucosal bleeding, and it is a diagnosis of exclusion. In some ITP cases, the disease is self-limiting, and treatment is not required, but chronic-persistent disease can also be developed. …”
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Molecular and pharmacological heterogeneity of ETV6::RUNX1 acute lymphoblastic leukemia by Zhenhua Li, Huanbin Zhao, Wenjian Yang, Maud Maillard, Satoshi Yoshimura, Yu-Chih Hsiao, Xin Huang, Yoshihiro Gocho, Lauren Rowland, Anthony Brown, Landon Choi, Kristine R. Crews, Charles G. Mullighan, Samuel W. Brady, Cheng Cheng, Ti-Cheng Chang, Gang Wu, Mignon L. Loh, Allen Eng Juh Yeoh, Federico Antillon-Klussmann, Sima Jeha, Hiroto Inaba, Jiyang Yu, Ching-Hon Pui, Seth E. Karol, William E. Evans, Jun J. Yang

“…Compared to C1, the C2 subtype features higher white blood cell counts and younger age at diagnosis, as well as better early treatment responses. …”
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The role of TRECs/KRECs as immune indicators that reflect immunophenotypes and predict the risk of infection in systemic autoimmune diseases by Takuji Itakura, Hirokazu Sasaki, Tadashi Hosoya, Natsuka Umezawa, Tetsuya Saito, Hideyuki Iwai, Hisanori Hasegawa, Hiroyuki Sato, Akihiro Hirakawa, Kohsuke Imai, Tomohiro Morio, Naoki Kimura, Shinsuke Yasuda

“…T cell receptor rearrangement excision circles (TRECs) and immunoglobulin κ-deleting recombination excision circles (KRECs) represent the lymphopoiesis capacity, widely used for newborn screening of inborn errors of immunity. …”
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Modulation of Blood Coagulation and Hematological Parameters by Crassocephalum crepidioides Leaf Methanol Extract and Fractions in STZ-Induced Diabetes in the Rat by Opeyemi O. Ayodele, Funmilayo D. Onajobi, Omolaja R. Osoniyi

“…The methanol extract and fractions of C. crepidioides at concentrations of 50, 100, and 200 mg/kg significantly prolonged the bleeding (58–200%), clotting (65–133%), prothrombin (176–441%), and activated partial thromboplastin (209–518%) times in diabetic rats compared to the control rats (LD50 ≥ 5000 mg/kg). …”
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Blockchain-based high transparent PKI authentication protocol by Liquan CHEN, Xiao LI, Zheyi YANG, Sijie QIAN

“…The public key infrastructure (PKI), as an significant component of the current Internet security infrastructure, guarantees the information transmission with the necessary authenticity, integrity, confidentiality and non-repudiation.However, the existing PKI also has shortcomings of excessive power of certification authority and difficulties in revoking and querying.Blockchain can be used to solve those problems by leveraging its advantages, such as decentralization, high transparency and flat structure.Furthermore, the ability and efficiency of the entire Internet to establish trust relationships may be improved.The transparent public key infrastructure (PKI) certification protocol based on the blockchain was proposed.The TS-PBFT algorithm was designed in the proposed protocol by adopting the threshold signature technology to the Practical Byzantine fault tolerance (PBFT) algorithm.The TS-PBFT algorithm reduced the communication overhead via reducing the communication complexity, strengthened the supervision via introducing external monitoring mechanism in the master node election of the view change protocol, and also improved the performance of the consensus mechanism via adding a batch processing mechanism.Moreover, a transparent blockchain-based PKI certification protocol was designed.The proposed protocol increased the security of certificate revocation and query, it also improved the efficiency of the certificate query by the introduction of counting bloom filters.Besides, the proposed protocol added audit function into the certificate lifecycle management.Accordingly, it can supervise the behavior of the certificate authority (CA), prompt it to improve security standards, and then achieve the purpose of limiting its authority.According to the security analysis and efficiency experiments, the proposed protocol was equipped with security properties, such as the resistance to spoofing certificate application attacks, and it achieved the best performance on TLS/SSL handshake time compared with existing PKI protocols.…”
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