A study on the current status of home-based pulmonary rehabilitation in stable chronic obstructive pulmonary disease patients and its impact on quality of life (稳定期慢性阻塞性肺疾病患者居家肺康复现... by WANG Tao (王涛), YAN Qiaoyuan (颜巧元), WU Hongyan (吴红艳), YANG Hualu (杨华露), ZHOU Juan (周娟), MO Beirong (莫蓓蓉), LIU Xianliang (刘贤亮)

“…The patents’ quality of life was associated with frequency of alcohol consumption, smoking habits, attempts to quit smoking, adherence to medication prescriptions, home oxygen therapy, duration of continuous oxygen therapy and number of days of respiratory training per week(P＜0. 01). …”
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Identifying the components of the administrative system employee empowerment model based on organizational intelligence and interpersonal relationships by fatemeh khoshhal, ali reza sargolzaie, zahra vazife

“…Semi-structured interviews were used to collect data and continued until reaching the theoretical saturation stage. …”
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Categorising implementation determinants and strategies within the US HIV implementation literature: a systematic review protocol by Justin D Smith, Brian Mustanski, Virginia McKay, James Lorenz Merle, Dennis Li, Brennan Keiser, Alithia Zamantakis, Artur Queiroz, Carlos G Gallo, Juan A Villamar, Juan Pablo Zapata, Nanette Benbow

“…Introduction Despite decreased rates of new infections, HIV/AIDS continues to impact certain US populations. In order to achieve the goals laid out in the Ending the HIV Epidemic (EHE) in the US initiative, implementation science is needed to expand the sustained use of effective prevention and treatment interventions, particularly among priority populations at risk for and living with HIV/AIDS. …”
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A first evaluation of the efficacy of minibeam radiation therapy combined with an immune check point inhibitor in a model of glioma-bearing rats by Lorea Iturri, Emmanuel Jouglar, Cristèle Gilbert, Julie Espenon, Marjorie Juchaux, Yolanda Prezado

“…Glioblastoma multiforme (GBM) continues to be a hopeless case today. Its treatment involves the use of multiple modalities. …”
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Optimization of Rh blood group antigen precision transfusion strategy across multiple hospital campuses by PDCA circle by YING Qiming, CHEN Luyan, DONG Kedi, HE Yiwen, ZHAN Yating, YANG Yexiaoqing, ZHAO Feng, LYU Dingfeng

“…[Results] After the continuous improvement with the PDCA cycle, the compatibility rate for the five Rh blood group antigen phenotypes between donors and recipients from August to October 2023 reached 81.90%, significantly higher than the 70.54% recorded during the pre-intervention phase (May to July 2022, P<0.01), and displayed a quarterly upward trend (β=0.028, P<0.05). …”
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Changes in the Expression of Mitochondrial Morphology-Related Genes during the Differentiation of Murine Embryonic Stem Cells by Jeong Eon Lee, Bong Jong Seo, Min Ji Han, Yean Ju Hong, Kwonho Hong, Hyuk Song, Jeong Woong Lee, Jeong Tae Do

“…During embryonic development, cells undergo changes in gene expression, signaling pathway activation/inactivation, metabolism, and intracellular organelle structures, which are mediated by mitochondria. Mitochondria continuously switch their morphology between elongated tubular and fragmented globular via mitochondrial fusion and fission. …”
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Metabolomic profiles of <i>Ribes nigrum</i> L. and <i>Lonicera caerulea</i> L. from the collection of the N.I. Vavilov Institute in the setting of Northwest Russia by T. V. Shelenga, V. S. Popov, A. V. Konarev, N. G. Tikhonova, O. A. Tikhonova, Y. A. Kerv, A. E. Smolenskaya, L. L. Malyshev

“…Because the direction of use depends on the biochemical properties of fruits, which are determined not only by species and varietal characteristics, but also by reproduction conditions, the study of the biochemical composition of fruits grown in various regions of the world continues to be relevant. In this regard, the collection of N.I. …”
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Annotated Checklist of Poroid Hymenochaetoid Fungi in Central Asia: Taxonomic Diversity, Ecological Roles, and Potential Distribution Patterns by Yusufjon Gafforov, Manzura Yarasheva, Xue-Wei Wang, Milena Rašeta, Yelena Rakhimova, Lyazzat Kyzmetova, Kanaim Bavlankulova, Sylvie Rapior, Jia-Jia Chen, Ewald Langer, Burkhon Munnavarov, Zafar Aslonov, Bobozoda Bakokhoja, Li-Wei Zhou

“…Our findings highlight the urgent need for continued mycological and host plant research and expanded conservation initiatives to document and preserve macrofungal and botanical biodiversity in this under-explored area. …”
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Using the optimal seed germination temperature approach to determine the potential distribution of Inga jinicuil in Mexico under climate change scenarios by Salvador Sampayo-Maldonado, Daniel Cabrera-Santos, Patricia Dávila-Aranda, Norma Isela Rodríguez-Arévalo, Alma Orozco-Segovia, Maraeva Gianella, Elizabeth Bell, Michael Way, Robert H. Manson, Gabina S. Quintas, Cesar M. Flores-Ortíz, Tiziana Ulian

“…More research on seed germination and growth is needed to improve the management and conservation of this species and its continued use as a shade tree in coffee agroforestry systems.…”
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Advances in Cell and Immune Therapies for Melanoma by Tanase Timis, Sanda Buruiana, Delia Dima, Madalina Nistor, Ximena Maria Muresan, Diana Cenariu, Adrian-Bogdan Tigu, Ciprian Tomuleasa

“…However, the limitations of the PD-1/PD-L1 and CTLA-4 axes inhibitors, such as low response rates, treatment resistance, and toxicity, have driven the need for continued research and advancements in treatment strategies. …”
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Computerized QT and QTc Measurements From Bedside ICU Monitors Are Similar to Those Derived From a Standard 12‐Lead ECG by Arthur Murray, Karolina Ho, Thomas J. Hoffmann, Gopika K. Ganesh, Shelvin Prasad, Sarah Berger, Cass Sandoval, Amy Larsen, Hildy Schell‐Chaple, Michele M. Pelter

“…Our hospital recently introduced bedside monitors in the intensive care unit (ICU) with continuous QT/QTc software. However, only four of the seven available ECG leads are used. …”
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From Natural Hosts to Agricultural Threats: The Evolutionary Journey of Phytopathogenic Fungi by Asanka Madhushan, Dulan Bhanuka Weerasingha, Evgeny Ilyukhin, Paul W. J. Taylor, Amila Sandaruwan Ratnayake, Jian-Kui Liu, Sajeewa S. N. Maharachchikumbura

“…The study of pathogen evolution has been transformed by advancements in molecular biology, genomics, and bioinformatics, utilizing methods like next-generation sequencing, comparative genomics, transcriptomics and population genomics. However, continuous research remains essential to monitor how pathogens evolve over time and to develop proactive strategies that mitigate their impact on agriculture.…”
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Protocol for the enhanced management of multimorbid patients with COPD and severe asthma: role of indoor air quality by Emili Vela, Isaac Cano, Josep Roca, Antoni Sisó-Almirall, Carme Hernandez, Ebymar Arismendi, Ramon Farré, Alba Gómez-López, María Figols, Antonio Montilla-Ibarra, Núria Sánchez-Ruano, Benigno Sánchez, Marta Sorribes, Jordi Piera-Jiménez, Jaume Benavent, Jose Fermoso, Rubèn González-Colom

“…Accordingly, the main objective is to implement a novel integrated care preventive service for enhanced management of these patients, as well as to evaluate its potential for value generation.Methods and analysis At the end of 2024, the specifics of the novel service will be defined through the articulation of its four main components: (1) enhanced lung function testing through oscillometry, (2) continuous monitoring of indoor air quality as a potential triggering factor, (3) digital support with an adaptive case management (ACM) approach and (4) predictive modelling for early identification and management of exacerbations. …”
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OCT Biomarkers in Neovascular Age-Related Macular Degeneration: A Narrative Review by Cristian Metrangolo, Simone Donati, Marco Mazzola, Liviana Fontanel, Walter Messina, Giulia D’alterio, Marisa Rubino, Paolo Radice, Elias Premi, Claudio Azzolini

“…OCT technology is evolving very quickly, and new retinal biomarkers are continuously described. This up-to-date review article provides a comprehensive description on how structural OCT-based biomarkers provide a valuable tool to monitor the progression of the disease and the treatment response in nAMD patients. …”
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Comprehensive self-tracking of blood glucose and lifestyle with a mobile application in the management of gestational diabetes: a study protocol for a randomised controlled trial (... by Henri Vähä-Ypyä, Harri Sievänen, Seppo Heinonen, Sari Niinistö, Suvi M Virtanen, Ilkka Korhonen, Mikko Kytö, Lisa Torsdatter Markussen, Pekka Marttinen, Giulio Jacucci, Tuuli E Korhonen, Saila B Koivusalo

“…Participants in the intervention group use the eMOM GDM app with continuous glucose metre (CGM) and activity bracelet for 1 week every month until delivery and an electronic 3-day food record every month until delivery. …”
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Axonal regeneration and innervation ratio following supercharged end-to-side nerve transfer by Leopold Harnoncourt, Martin Schmoll, Christopher Festin, Laurenz Pflaum, Markus Breuss, Johanna Klepetko, Dominik C. Dotzauer, Florian J. Jaklin, Udo Maierhofer, Philipp Tratnig-Frankl, Oskar C. Aszmann, Oskar C. Aszmann

“…In these cases, supercharged end-to-side (SETS) nerve transfers preserve the continuity of the original nerves while facilitating additional axonal support to mitigate muscle atrophy. …”
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Preventing Severe COVID-19 with Tixagevimab-Cilgavimab in Hematological Patients Treated with Anti-CD20 Monoclonal Antibodies: An International Multicenter Study by Hovav Azuly, Tali Shafat, Daniel Grupel, Tzvika Porges, Ran Abuhasira, Ana Belkin, Ofir Deri, Yonatan Oster, Shadi Zahran, Ehud Horwitz, Netanel A. Horowitz, Hazim Khatib, Marjorie Vieira Batista, Anita Cassoli Cortez, Tal Brosh-Nissimov, Yafit Segman, Linor Ishay, Regev Cohen, Alaa Atamna, Amy Spallone, Roy F. Chemaly, Juan Carlos Ramos, Michal Chowers, Evgeny Rogozin, Noga Carmi Oren, Şiran Keske, Orit Wolfovitz Barchad, Lior Nesher, on behalf of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Study Group for Respiratory Viruses (ESGREV)

“…Even though T-C is ineffective against current variants, these findings highlight the importance of additional protective measures and the continued development of monoclonal antibodies to protect immunocompromised individuals to mitigate the impact of COVID-19 and other respiratory viral diseases.…”
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EDF1 accelerates ganglioside GD3 accumulation to boost CD52-mediated CD8+ T cell dysfunction in neuroblastoma by Di Li, Meng Li, Zhenjian Zhuo, Huiqin Guo, Weixin Zhang, Yile Xu, Hai-Yun Wang, Jiabin Liu, Huimin Xia, Huiran Lin, Jue Tang, Jing He, Lei Miao

“…Dysfunction and apoptosis in immune cells result from the exposure to continuous tumor-related antigen stimulation and coinhibitory signals. …”
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Compost quality optimization through Plackett-Burman’s design by Luis Felipe Ortiz-Dongo, Yerly Mendez-Revollar, Richard Solórzano-Acosta, Sphyros Lastra, Gladys Carrión-Carrera

“…Conclusion: These findings provide a solid foundation for composting practice's continuous improvement, contributing to high-quality organic fertilizer production more efficiently and sustainably. …”
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LoSI: Large Scale Location Inference Through FM Signal Integration and Estimation by Tathagata Mukherjee, Piyush Kumar, Debdeep Pati, Erik Blasch, Eduardo Pasiliao, Liqin Xu

“…The algorithm uses a large-scale model estimation phase that computes the expected FM spectrum in small rectangular cells (realized using geohashes) across the Contiguous United States (CONUS). We define and use Dominant Channel Descriptor (DCD) features, which can be used for positioning using time varying models. …”
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