BAFF and APRIL immunotherapy following Bacille Calmette-Guérin vaccination enhances protection against pulmonary tuberculosis in mice by Min Xie, Chen-Yu Tsai, Joshua Woo, Frank Nuritdinov, Melissa Cristaldo, Narineh M. Odjourian, Rosleine Antilus-Sainte, Maureen Dougher, Martin Gengenbacher, Martin Gengenbacher

“…Importantly, mice receiving BCG vaccination followed by BAFF or APRIL immunotherapy exhibited superior long-term protection against pulmonary tuberculosis relative to controls that received only BCG.ConclusionIn summary, our findings demonstrate that combining BCG vaccination with B cell targeted immunomodulatory therapies can improve long-term protection against pulmonary tuberculosis, highlighting the continued relevance and underutilized potential of BCG as a vaccine platform.…”
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A Longer Duration of Intravenous Antibiotic Treatment for Patients with Early Periprosthetic Joint Infections Is Not Associated with a Lower Failure Rate by Janneke Meijer, Alex Soriano, Wierd Zijlstra, Bas ten Have, Saad Tarabichi, Paul Jutte, Javad Parvizi, Marjan Wouthuyzen-Bakker

“…Conclusions: In early post-operative PJIs, a longer duration of IV therapy is not associated with a lower failure rate but may be continued until a sufficient bacterial load reduction has been achieved.…”
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Short-term effects of empagliflozin on preventing contrast induced acute kidney injury in patients undergoing percutaneous coronary intervention, a randomised trial by Zeinab Sadat Hosseini, Mohammad Javad Jamili, Behzad Ensan, Ghazaleh Donyadideh, Bahram Shahri, Hamid Eshraghi, Susan Darroudi, Mohsen Moohebati

“…Participants were randomly assigned to receive empagliflozin (10 mg daily) or a placebo, starting one day before PCI and continuing for two days post-procedure. Renal function parameters such as estimated glomerular filtration rate (eGFR), creatinine, cystatin C, and urea were evaluated. …”
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Assessing survey design changes of long-term fishery-independent groundfish trawl surveys in the Gulf of Mexico by Adam G. Pollack, Eric R. Hoffmayer, Theodore S. Switzer, David S. Hanisko, Jill M. Hendon, John Mareska, Fernando Martinez-Andrade, Jeff Rester, Zachary C. Zuckerman, Gilmore Pellegrin

“…Starting in 1981, the Southeast Area Monitoring and Assessment Program began groundfish surveys, continuing the time series. Over time, the survey’s spatial extent and design have been altered to meet changing management needs. …”
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Design of an Integrated Model Combining CycleGAN, PPO, and Vision Transformer for Adaptive Scene Rendering in the Metaverse by Durga Prasad Kavadi, Kailash Chandra Mishra, Sai Babu Veesam, Mudimela Madhusudhan, Palacharla Ravi Kumar, Pannangi Naresh, Yuvaraju Chinnam

“…The CycleGAN module ensures the production of the high-resolution scenes even from low-resolution inputs, whereas PPO provides for continuous adaptation of rendering parameters so as to reduce latency and computational load. …”
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An initial exploration of core collection construction and DNA fingerprinting in Elymus sibiricus L. using SNP markers by Xinrui Li, Xinrui Li, Xinrui Li, Daping Song, Mingfeng Li, Daxu Li, Minghong You, Yan Peng, Jiajun Yan, Shiqie Bai

“…This study not only provides a reference for the continued collection and identification of E. sibiricus germplasm resources but also offers a scientific basis for their conservation and utilization.…”
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The Rise of SARS-CoV-2 Variants and the Role of Convalescent Plasma Therapy for Management of Infections by Mohamed, Moubarak, Keneth Iceland, Kasozi, Helal F., Hetta, Hazem M., Shaheen, Abdur, Rauf, Hayder M., Al-kuraishy, Safaa, Qusti, Eida M., Alshammari, Emmanuel Tiyo, Ayikobua, Fred, Ssempijja, Adam Moyosore, Afodun, Ritah, Kenganzi, Ibe Michael, Usman, Juma John, Ochieng, Lawrence Obado, Osuwat, Kevin, Matama, Ali I., Al-Gareeb, Emmanuel, Kairania, Monica, Musenero, Susan, Christina Welburn, Gaber, El-Saber Batiha

“…Novel therapies for the treatment of COVID-19 are continuing to emerge as the SARS-Cov- 2 pandemic progresses. …”
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First detection of Culex tritaeniorhynchus in Western Australia using molecular diagnostics and morphological identification by Kimberly L. Evasco, Craig Brockway, Tamara Falkingham, Margaret Hall, Nerida G. Wilson, Abbey Potter

“…When the species was detected in the country’s Northern Territory (NT) for the first time, the Western Australia (WA) Department of Health was cognisant of the risk it posed to the State because of the shared border and continuous mosquito habitat adjoining the two jurisdictions. …”
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Treatment Patterns of Long-Acting Somatostatin Analogs for Neuroendocrine Tumors by Callisia N. Clarke, Paul Cockrum, Thomas J.R. Beveridge, Michelle Jerry, Donna McMorrow, Anh Thu Tran, Alexandria T. Phan

“…Dose escalation was defined as increases in quantity or frequency. Continuous variables, categorical variables, and Kaplan-Meier estimated treatment durations were compared using _t_-tests, chi-square/Fisher’s tests, and log-rank tests, respectively. …”
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Evaluation of the Education Plan and Activities of Swiss Sport Integrity. A report of a science-practice co-operation. by Christoffer Klenk, Jonas Personeni

“…Then transferability to other science-practice co-operations is briefly discussed. Concluding, the continuation and expansion of the existing cooperation with the entry into force of the new WADA Code 2027 will be briefly outlined. …”
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Requirements for Universally Accessible Upper-Body Exercise Equipment: The Case of People with Spinal Cord Injuries in Korea by Kwang-Ok An, Myo-Jung Choi, Sung-Shin Kim, Bo-Ra Kang, Young-Hyeon Bae, Hyosun Kweon

“…Especially for individuals with paraplegia with spinal cord injuries, it is necessary to maintain continuous participation in physical activity even after discharge, as it helps to maintain mobility and daily living activities through upper body strength. …”
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ON THE SPECIFICS OF TEACHING, SCHOOLS AND INTELLECTUAL CENTERS OF PALESTINE OF LATE ANTIQUITY by Zhanna M. Sukhova, Irina Yu. Vashcheva

“…The image of the intellectual and educational centers of Palestine is vivid, where debates and discussions continued almost until the end of the era of Late Antiquity. …”
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Chromosomal analysis and short-term outcome of prenatally diagnosed congenital heart disease by Marcellino Verbeke, Laurens Hannes, Koen Devriendt, Kris Van den Bogaert, Bjorn Cools, Luc De Catte, Marc Gewillig, Jeroen Breckpot

“…Interestingly, a prenatal genetic diagnosis was negatively correlated with pregnancy continuation, but it was not a significant predictor for postnatal mortality, while a postnatal diagnosis of a genetic disorder impacted early but not late postnatal mortality. …”
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EVALUATING THE IMPACT OF MASS TOURISM ON THE HOSPITALITY INDUSTRY AND TOURISM DESTINATION DEVELOPMENT OF CROSS RIVER STATE, NIGERIA by Nnana Okoi OFEM, Chinasa UTTAH, Ndem Samuel ETIM, Queen Olubukola AYENI, Josephat Owan EMEKA, Agnes Awoli EWURU, Maxwell-Borjor Achuk EBA, Eja Iwara EJA, Jeremiah ABANBESHIE, Daniel Daniel JAMES, Ayuk Awunghe ACHU, Michael Takim OTU, Fidelis Ngaji AKWAJI, Etta Oyen ETTA

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PICT: A low‐cost, modular, open‐source camera trap system to study plant–insect interactions by Vincent Droissart, Laura Azandi, Eric Rostand Onguene, Marie Savignac, Thomas B. Smith, Vincent Deblauwe

“…We developed PICT (plant–insect interactions camera trap), an inexpensive (<100 USD) do‐it‐yourself CT system based on a Raspberry Pi Zero computer designed to continuously film animal activity. The system is particularly well suited for the study of pollination, insect behaviour and predator–prey interactions. …”
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Evidence that the domesticated fungus Leucoagaricus gongylophorus recycles its cytoplasmic contents as nutritional rewards to feed its leafcutter ant farmers by Caio Ambrosio Leal-Dutra, Lok Man Yuen, Bruno Augusto Maciel Guedes, Marta Contreras-Serrano, Pedro Elias Marques, Jonathan Zvi Shik

“…This imaging showed that the cultivar uses a process called autophagy to recycle its own cellular material (e.g. cytosol, mitochondria) and then shuttles the resulting metabolites into a vacuole whose continual expansion displaces other organelles and causes the gongylidium cell’s bulging bulb-like appearance. …”
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MODERN TREATMENT OF METASTATIC MELANOMA: FROM STANDARDS TO AN INDIVIDUALIZED APPROACH IN REAL CLINICAL PRACTICE by N. V. Zhukova, R. V. Orlova, N. Yu. Antimonik, S. I. Kutukova, N. P. Belyak, N. V. Popova, S. P. Erdniev

“…The life expectancy of the patient from the moment of diagnosing the metastatic stage of the disease is 3.5 years, while 2.5 years on the background of nivolumab therapy. Patient monitoring continues.…”
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Community perceptions and determinants of obstetric fistula across gender lines by Wagaye Fentahun Chanie, Aster Berhe, Ambaye Dejen Tilahun, Bikis Liyew, Chernet Baye, Tarekegn Asemaw Akalie, Destaye Shiferaw Alemu, Miteku Andualem Limenih

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An Interactive Pain Application (MServ) Improves Postoperative Pain Management by Richard Gordon-Williams, Andreia Trigo, Paul Bassett, Amanda Williams, Stephen Cone, Martin Lees, Brigitta Brandner

“…Opioids are the cornerstone of treating severe pain after surgery but cause problems when continued long after discharge. We investigated the efficacy of multifunction pain management software (MServ) in improving postoperative pain control and reducing opioid prescription at discharge. …”
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Deep learning based decision-making and outcome prediction for adolescent idiopathic scoliosis patients with posterior surgery by Kai Chen, Xiao Zhai, Ziqiang Chen, Haojue Wang, Mingyuan Yang, Changwei Yang, Yushu Bai, Ming Li

“…Variables such as age, gender, preoperative and final follow-up horizontal and vertical coordinate vectors, and screw positioning data were preprocessed by parameterizing image data and transforming various data types into a unified, continuous high-dimensional feature space. Four deep learning models were designed, including Multi-Layer Perceptron model, Encoder-Decoder model, CNN-LSTM Attention model and Deep FM model. …”
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