High vulnerability of the endemic Southern Ocean snail Neobuccinum eatoni (Buccinidae) to critical projected oceanographic changes by Rosvita González, Luis R. Pertierra, Pablo C. Guerrero, Angie Díaz

“…However, in both scenarios, a reduction in habitat suitability is expected in certain sectors around the Antarctic continent and the Kerguelen Archipelago. By 2100, under the moderate emissions scenario (SSP2-4.5), the species is projected to move to deeper areas and lower latitudes, with notable expansions in the Weddell Sea and in the Southern Ocean surrounding the Kerguelen Archipelago. …”
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Clinical value of motor function of digestive system investigation: past, present and future by A. S. Trukhmanov, O. A. Storonova, V. T. Ivashkin

“…This method allows to estimate obturative function of rectal sphincter, intestinal component of stool continence.Conclusion. Clinical value of digestive system motor function investigation grows steadily and skill to diagnose disorders of peristaltic activity according to symptoms can and should be complemented by with modern methods of esophageal, gastric and intestinal motor activity registration.…”
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Educating the future: Serbian healthcare students’ knowledge and attitudes toward urinary incontinence by Dragana Milutinović, Dragana Simin, Marijana Ostoić, Sonja Golubović, Dragana Živković

“…In many countries, they, as future healthcare professionals, must also have continence care competency before graduation. Therefore, the study aimed to assess the knowledge and attitudes of healthcare students toward UI. …”
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Enhanced recovery after surgery society’s recommendations for liver surgery reduces non surgical complications by Robert Oehring, Eriselda Keshi, Karl-Herbert Hillebrandt, Pia F. Koch, Matthäus Felsenstein, Simon Moosburner, Wenzel Schöning, Nathanael Raschzok, Johann Pratschke, Jens Neudecker, Felix Krenzien

“…The effect of the ERAS program progressively improved over the years, highlighting the need for continuous effort to maintain and further enhance outcomes.…”
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Evaluation Method of the Gas Hydrate and Free Gas System and Its Application in the Shenhu Area, South China Sea by Pibo Su, Tingwei Li, Shurong Liang, Jinqiang Liang, Xiaoxue Wang, Xiaoming Wan, Feifei Wang, Fang Liu

“…Gas hydrate is located above free gas and distributed continuously. In plane form, gas hydrate and free gas both present subelliptical distribution in the NW-SE direction. …”
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A multicenter, randomized, double-blind trial comparing LY01011, a biosimilar, with denosumab (Xgeva®) in patients with bone metastasis from solid tumors by Mingchuan Zhao, Xichun Hu, Pengpeng Zhuang, Aiping Zeng, Yan Yu, Zhendong Chen, Hongmei Sun, Weihua Yang, Lili Sheng, Peijian Peng, Jingfen Wang, Tienan Yi, Minghong Bi, Huaqiu Shi, Mingli Ni, Xiumei Dai, Changlu Hu, Hongjie Xu, Dongqing Lv, Qingshan Li, Kaijian Lei, Xia Yuan, Ou Jiang, Xicheng Wang, Baihui Hu, Zhe Hou, Zhaoping Su, Song Zheng, Ming Zhou, Changlin Dou

“…Materials and methods: Eligible patients with BM from solid tumors were randomized at a 1:1 ratio to receive 120 mg of LY01011 or 120 mg of denosumab subcutaneously every four weeks during a 12-week double-blind treatment period, and then all enrolled patients continued to receive LY01011 until week 53. The primary endpoint was the natural logarithm of change of the urinary N-terminal crosslinked telopeptide of type I collagen level normalized to the urine creatinine level (uNTX/uCr) at week 13 from baseline. …”
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Towards faster plan adaptation for proton arc therapy using initial treatment plan information by Benjamin Roberfroid, Margerie Huet-Dastarac, Elena Borderías-Villarroel, Rodin Koffeing, John A. Lee, Ana M. Barragán-Montero, Edmond Sterpin

“…Background and Purpose: Proton arc therapy (PAT) is an emerging modality delivering continuously rotating proton beams. Current PAT planning approaches are time-consuming, making them unsuitable for online adaptation. …”
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Error-Prone Translesion DNA Synthesis by Escherichia coli DNA Polymerase IV (DinB) on Templates Containing 1,2-dihydro-2-oxoadenine by Masaki Hori, Shin-Ichiro Yonekura, Takehiko Nohmi, Petr Gruz, Hiroshi Sugiyama, Shuji Yonei, Qiu-Mei Zhang-Akiyama

“…Reactive oxygen species (ROS) are generated continuously during normal metabolism and as a result of exogenous stress such as ionizing radiation. …”
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Long-term effect of island industrial construction on groundwater health risk by Yong Huang, Daqing Wang, Haoli Xu, Zhao Lu, Zijian Cheng, Zhibin Ding, Yi Wang, Yue Shi, Huiru Cui, Xiaoying Lian

“…On some islands, the main source of residential water is groundwater, whose quality is seriously threatened by continuous industrial construction in island areas. …”
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Molecular profiling of bladder cancer xenografts defines relevant molecular subtypes and provides a resource for biomarker discovery. by Sharada Mokkapati, Ganiraju Manyam, Alexis R. Steinmetz, Côme Tholomier, Alberto Martini, Woonyoung Choi, Bogdon Czerniak, Byron H Lee, Colin P Dinney, David J McConkey

“…Ki67 was assessed as a continuous percentage of positively stained cells. Morphological assessment of xenografts included H&E and α-SMA staining. …”
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Predicting cardiovascular disease and all-cause mortality using the lymphocyte-to-monocyte ratio: Insights from explainable machine learning models by Jichao Wu, Die Huang, Jiefang Li, Jingxing Yi, Yu Lei, Jun Yin

“…Background: Cardiovascular disease (CVD) is a leading cause of death globally, with its incidence and mortality rates continuing to rise. While commonly used biomarkers such as low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and blood glucose are widely applied, they have certain limitations. …”
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The evolutionary journey to a new normal for learning and capacity building of healthcare workers to prepare and respond to health emergencies across Africa by Boukaré Bonkoungou, Fausta Mosha, Amarachi Abianuru, Joseph Okeibunor, Heini Utunen, Giselle Balaciano, Ana C. Barbosa de Lima, Lauren Burke, Shannon McKenna, Sukriti Nag, Abdou Salam Gueye, Bruce Struminger

“…However, to sustain this momentum and further expand access to critical knowledge, stakeholders must commit to continued investment in digital learning infrastructure, training, and technology.…”
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Possible accumulation of emerging contaminants of concern in treated wastewater on the soil plant system of a processing tomato-wheat succession by Giuseppe Gatta, Federica Carucci, Anna Gagliardi, Michele Perniola, Michele Denora, Francesco De Mastro, Gennaro Brunetti, Sapia Murgolo, Cristina De Ceglie, Alfieri Pollice, Marcella Michela Giuliani

“…These findings underscore the potential of using TWW for irrigation without compromising food safety in crops like tomatoes and durum wheat. However, continued monitoring and further research are essential to fully understand the long-term effects of ECCs on agricultural systems and ensure the protection of both human health and the environment.…”
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AI-based carbon peak prediction and energy transition optimization for thermal power industry in energy-intensive regions of China by Chenhao Huang, Zhongyang Lin, Jian Wu, Penghan Li, Chaofeng Zhang, Yanzhao Liu, Weirong Chen, Xin Xu, Jinsong Deng

“…Despite its recent increasing adoption of renewable energy, China continues to generate excessive emissions, particularly from its dominant thermal power sector. …”
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Healthy lifestyle before and during pregnancy to prevent childhood obesity: study protocol for a parallel group randomised trial — the PRE-STORK trial by Tina Vilsbøll, Signe S Torekov, Julie Lyng Forman, Romain Barrès, Andreas Andersen, Filip K Knop, Signe Foghsgaard, Klaus Bønnelykke, Thomas Bergholt, Karoline Kragelund Nielsen, Christina Anne Vinter, Majken Lillholm Pico, Louise Groth Grunnet, Nina Kornerup, Julie Hagstrøm Danielsen, Ronni Eg Sahl, Mette Yun Johansen, Louise Kelstrup, Nida Ghauri, Emilie Grønlund, Lærke Lund

“…The ‘healthy lifestyle before and during pregnancy to prevent childhood obesity — the PRE-STORK trial’ aims to provide insights into the effect of a lifestyle intervention initiated before conception and continued during pregnancy in women with overweight or obesity, on neonatal adiposity in their children.Methods and analysis In this randomised, two-arm, parallel-group, controlled trial, we will include 360 women with overweight or obesity (aged 18–40; body mass index 25–44 kg/m2) and their partners. …”
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Ion beam induced secondary electron tomography of acrylonitrile-styrene-acrylate/polycarbonate polymer blends for fused filament fabrication and injection moulding by J. Hernández-Saz, D. Moreno-Sanchez, L. M. Valencia, Y. Gómez, S. I. Molina, M. Herrera

“…Blends obtained by FFF exhibit strong directionality and a co-continuous morphology, whereas IM objects present a droplet-matrix structure. …”
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Associations of prenatal urinary melamine, melamine analogues, and aromatic amines with gestational duration and fetal growth in the ECHO Cohort by Giehae Choi, Xiaoshuang Xun, Deborah H. Bennett, John D. Meeker, Rachel Morello-Frosch, Sheela Sathyanarayana, Susan L Schantz, Leonardo Trasande, Deborah Watkins, Edo D. Pellizzari, Wenlong Li, Kurunthachalam Kannan, Tracey J. Woodruff, Jessie P. Buckley

“…We estimated beta coefficients and 95% confidence intervals (CIs) using adjusted linear mixed models with continuous dilution-standardized concentrations (log2 transformed and scaled by interquartile range, IQR) or binary indicators for detection. …”
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A self-configuration framework for balancing services in the fog of things by Edson Mota, Jurandir Barbosa, Gustavo B. Figueiredo, Maycon Peixoto, Cássio Prazeres

“…This integration allows the system to continuously monitor the network state and automatically reconfigure the service distribution in response to changes, such as adding or removing nodes. …”
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Tropical Rice Mapping Using Time-Series SAR Images and ESF-Seg Model in Hainan, China, from 2019 to 2023 by Yazhe Xie, Lu Xu, Hong Zhang, Mingyang Song, Ji Ge, Fan Wu

“…As indicated by the rice mapping products, the proposed method preserves the integrity of the rice parcels in the fragmented croplands, thus providing a new opportunity for the continuous monitoring of tropical rice distribution with high accuracy.…”
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Targeting unique ligand binding domain structural features downregulates DKK1 in Y537S ESR1 mutant breast cancer cells by K. S. Young, G. R. Hancock, E. C. Fink, A. Zigrossi, B. Flowers, D. A. Cooper, V. T. Nguyen, M. C. Martinez, K. S. Mon, M. Bosland, D. R. Zak, A. P. Runde, M. N. Sharifi, I. Kastrati, D. D. L. Minh, S. Kregel, Sean W. Fanning

“…Mutations to estrogen receptor alpha (ERα) arise after continued therapeutic pressure. Next generation selective estrogen receptor modulators and degraders/downregulators (SERMs and SERDs) show clinical efficacy, but responses are often non-durable. …”
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