Upregulating Nonneuronal Cholinergic Activity Decreases TNF Release from Lipopolysaccharide-Stimulated RAW264.7 Cells by Yi Lv, Sen Hu, Jiangyang Lu, Ning Dong, Qian Liu, Minghua Du, Huiping Zhang

“…Therefore, we explored whether LPS continuous stimulation could upregulate the nonneuronal cholinergic activity in macrophages and whether increasing autocrine ACh could decrease TNF release from the macrophages. …”
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Dual Jet Interaction, Magnetically Arrested Flows, and Flares in Accreting Binary Black Holes by Sean M. Ressler, Luciano Combi, Bart Ripperda, Elias R. Most

“…We provide estimates for the associated electromagnetic emission for both processes, showing that they likely accelerate electrons to high energies and are promising candidates for continuous, stochastic, and/or quasi-periodic higher-energy electromagnetic emission. …”
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DAShip: A Large-Scale Annotated Dataset for Ship Detection Using Distributed Acoustic Sensing Technique by Wenjin Huang, Shaoyi Chen, Yichang Wu, Ruihua Li, Tianrui Li, Yihua Huang, Xiaochun Cao, Zhaohui Li

“…As the emerging remote sensing technology, distributed acoustic sensing (DAS) technology which continuously detects vibrations along underwater optical fiber cables facilitates all-weather, all-day, and real-time ship detection capabilities, possessing the potential for detecting dark ships. …”
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Impact of adjuvant trastuzumab therapy and its discontinuation on cardiac function and mortality in patients with early-stage breast cancer: An analysis based on the Japanese Recei... by Keiko Miyazato, Hiroshi Ohtsu, Akihiko Shimomura, Naohiro Yonemoto, Chikako Shimizu, Kazuhiro Sase, Shinichiro Ueda

“…Incidentally, there are still unclear whether or not trastuzumab treatment should be continued in the setting of reduced cardiac function. …”
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Study on the Adsorption Mechanism of Hydrophobic SiO2 Nanoparticles: A Molecular Dynamics Study by Runnan Zhou, Yuyuan Wang, Dong Zhang, Peng Ye, Jianguang Wei

“…ABSTRACT In recent years, with increasing global demand for oil and gas resources and continuous decline in conventional oil and gas production, the global development focus has shifted from conventional medium to high permeability reservoirs to low permeability and tight oil reservoirs. …”
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Multiple viral infections and antimicrobial use in hospitalized children with respiratory illness during pandemic and early post-pandemic era, Taiwan by Chyi-Liang Chen, Yi-Ching Chen, Hsuan-Ling Hsiao, Yi-Jung Chang, Hsin-Chieh Li, Merve Arslan Aydin, Cheng-Hsun Chiu

“…Pediatric physicians continued to use antibiotics for febrile symptoms in hospitalized children with respiratory illness, even when viral pathogens were identified.…”
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Neural Determinants of Sedentary Lifestyle in Older Adults: A Brain Network Analysis by Mohsen Bahrami, Jonathan H Burdette, Paul J Laurienti, Barbara J Nicklas, W Jack Rejeski, Jason Fanning

“…ABSTRACT Purpose The prevalence of sedentary lifestyles (SL), which includes both high volumes of extended sitting behavior and a low volume of steps accumulated across the day, among older adults continues to rise contributing to increases in associated comorbidities and the loss of independence. …”
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Scurvy as a Cause of Leg Pain and Limp in Pediatric and Adolescent Patients by Christopher J. DeFrancesco, MD, David Kell, BA, Sean Owens, BS, Matt Grady, MD, Naomi Brown, MD

“…Key Concepts: (1) Scurvy, the condition caused by vitamin C deficiency, is not a historical disease, with research suggesting that its incidence in the US is on the rise. (2) Scurvy can result in lower extremity pain and limping among children, who may present for orthopaedic evaluation. (3) An increased index of suspicion for vitamin C deficiency should be maintained for any child with a history of restrictive eating, especially those with a history of autism spectrum disorder. (4) Orthopaedic providers should know the specific MRI and x-ray findings characteristic of vitamin C deficiency. (5) Vitamin C levels can be repleted in weeks with proper supplementation, but children with scurvy due to restrictive eating generally require continued intervention from nutrition and/or feeding specialists.…”
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Revisiting the Synergistic In Vitro Antimicrobial and Antibiofilm Potential of Chlorhexidine Gluconate and Cetrimide in Combination as an Antiseptic and Disinfectant Agent by Diamond Jain, Rimjhim Gupta, Rashmi Mehta, Pratheesh N. Prabhakaran, Deva Kumari, Kulpreet Bhui, Deepa Murali

“…Overall, it can be inferred that the combination of chlorhexidine and cetrimide is a potential biocide that continues to be relevant for use in antisepsis and disinfection against infection-causing pathogens.…”
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Study of Long-term Spectral Evolution and X-Ray and γ-Ray Correlation of Blazars Seen by HAWC by R. Alfaro, C. Alvarez, A. Andrés, J.C. Arteaga-Velázquez, D. Avila Rojas, H.A. Ayala Solares, R. Babu, E. Belmont-Moreno, A. Bernal, K.S. Caballero-Mora, T. Capistrán, A. Carramiñana, F. Carreón, S. Casanova, U. Cotti, J. Cotzomi, S. Coutiño de León, E. De la Fuente, D. Depaoli, N. Di Lalla, R. Diaz Hernandez, B.L. Dingus, M.A. DuVernois, M. Durocher, J.C. Díaz-Vélez, K. Engel, C. Espinoza, K.L. Fan, N. Fraija, S. Fraija, J.A. García-González, F. Garfias, A. Gonzalez Muñoz, M.M. González, J.A. Goodman, S. Groetsch, J.P. Harding, S. Hernández-Cadena, I. Herzog, D. Huang, F. Hueyotl-Zahuantitla, A. Iriarte, V. Joshi, S. Kaufmann, D. Kieda, A. Lara, W.H. Lee, J. Lee, H. León Vargas, J.T. Linnemann, A.L. Longinotti, G. Luis-Raya, K. Malone, O. Martinez, I. Martinez-Castellanos, J. Martínez-Castro, J.A. Matthews, P. Miranda-Romagnoli, J.A. Montes, E. Moreno, M. Mostafá, A. Nayerhoda, L. Nellen, M.U. Nisa, R. Noriega-Papaqui, N. Omodei, M. Osorio, Y. Pérez Araujo, E.G. Pérez-Pérez, C.D. Rho, D. Rosa-González, E. Ruiz-Velasco, H. Salazar, D. Salazar-Gallegos, A. Sandoval, M. Schneider, J. Serna-Franco, A.J. Smith, Y. Son, R.W. Springer, O. Tibolla, K. Tollefson, I. Torres, R. Torres-Escobedo, R. Turner, F. Ureña-Mena, E. Varela, L. Villaseñor, X. Wang, I.J. Watson, K. Whitaker, E. Willox, S. Yun-Cárcamo, H. Zhou, C. de León, HAWC collaboration, Abraham D. Falcone, Fredric Hancock

“…The HAWC Observatory collected 6 yr of extensive data, providing an ideal platform for long-term monitoring of blazars in the very high energy (VHE) band, without bias toward specific flux states. HAWC continuously monitors blazar activity at TeV energies, focusing on sources with a redshift of z ≤ 0.3, based on the Third Fermi-LAT Catalog of High-Energy sources. …”
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Oral dydrogesterone versus oral micronized progesterone in threatened miscarriage: protocol paper for a randomized controlled trial by Alka Kriplani, Gouri Shankar Kamilya, T Ramani Devi, Ashima Taneja, Amol Pawar, Gayathri Karthik Nagesh, Tapan Pattanaik, Tanusree Gupta, Mahima Jain, Monjori Mitra

“…A total of 304 eligible pregnant women aged 20–39 years, diagnosed with threatened miscarriage, will be enrolled during 5–12 weeks of gestation and randomized equally to receive either oral dydrogesterone (40 mg stat, followed by 10 mg three times a day) or oral micronized progesterone (200 mg two times a day) up to one week after stoppage of bleeding or if bleeding does not stop, then treatment will be continued till a maximum of 14 weeks of gestation (unless miscarriage is confirmed earlier or the investigator decides to prolong treatment for better outcome or if bleeding relapses). …”
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Case report: Pseudoprogression mimicking neoplastic recurrence three months after completion of proton beam therapy for an IDH-mutant astrocytoma CNS WHO grade 3 by Liv Cathrine Heggebø, Liv Cathrine Heggebø, Ida Maria Henriksen Borgen, Ida Maria Henriksen Borgen, Hanne Blakstad, Hanne Blakstad, Cathrine Saxhaug, Pål André Rønning, Pitt Frederik Niehusmann, Katja Werlenius, Malin Blomstrand, Malin Blomstrand, Petter Brandal, Petter Brandal

“…Adjuvant chemotherapy with temozolomide was continued.ConclusionThe presented case clearly shows that caution must be taken when interpreting cerebral MRI changes postradiation, and in particular after proton therapy. …”
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Evaluation of the Effectiveness of Using STEAM Projects in Teaching Physics: Student Interest in the Field of Solar Energy by Amin Pattayev, Naci Genc, Sherzod Ramankulov, Serik Polatuly, Meirbek Tuiyebayev, Indira Usembayeva, Gulnara Rizakhojayeva

“…The educational process continued for 15 weeks. In this feature, pre- and post-participation calculations, especially surveys, and progress calculations are used to create a student score. …”
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A Newborn with Genital Ambiguity, 45,X/46,XY Mosaicism, a Jumping Chromosome Y, and Congenital Adrenal Hyperplasia by Lei Zhang, Linda D. Cooley, Sonal R. Chandratre, Atif Ahmed, Jill D. Jacobson

“…Histologically, the right gonad had irregular, distended seminiferous tubules with hyperplastic germ cells contiguous with ovarian stroma and primordial follicles. …”
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Does welfare technology contribute to security, activity, participation and independence within municipal elder care? A qualitative study protocol by Ingrid Hellström, Johannes Österholm, Åsa Larsson Ranada, Katarina Baudin, Vedrana B Baric

“…As the ageing population continues to rise, the strain on welfare resources both, human and financial, intensifies. …”
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DeepGlioSeg: advanced glioma MRI data segmentation with integrated local-global representation architecture by Ruipeng Li, Yuehui Liao, Yueqi Huang, Xiaofei Ma, Guohua Zhao, Yanbin Wang, Chen Song

“…However, this task is hindered by substantial heterogeneity within gliomas and imbalanced region distributions, posing challenges to existing segmentation methods.MethodsTo address these challenges, we propose the DeepGlioSeg network, a U-shaped architecture with skip connections for continuous contextual feature integration. The model includes two primary components. …”
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AutoMEX: Streamlining material extrusion with AI agents powered by large language models and knowledge graphs by Haolin Fan, Junlin Huang, Jilong Xu, Yifei Zhou, Jerry Ying Hsi Fuh, Wen Feng Lu, Bingbing Li

“…While the framework shows promising potential, challenges such as the computational demands of advanced LLMs and the need for continual updates to the KG remain areas for future work. …”
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Development and Implementation of an IoT-Based Early Flood Detection and Monitoring System Utilizing Time Series Forecasting for Real-Time Alerts in Resource-Constrained Environmen... by Nik Nor Muhammad Saifudin Nik Mohd Kamal, Ahmad Anwar Zainuddin, Abu Ubaidah Shamsudin, Muhamad Syariff Sapuan, Muhammad Hazim Amin Samsudin, Mohammad Adam Haikal Zulkfli

“…The system uses commonly accessible components such as NodeMCU ESP8266, HC-SRO4 Ultrasonic Sensors, and MAX7219 Dot Matrix Displays to build a sensor network in flood-prone locations. These sensors continually send data to a central processing unit for analysis, and a machine learning model based on Time Series forecasting is used for predictive analysis in the ThingSpeak platform, which is available via an internet dashboard for real-time monitoring. …”
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Automatic Segmentation of Abdominal Aortic Aneurysm From Computed Tomography Angiography Using a Patch-Based Dilated UNet Model by Merjulah Roby, Juan C. Restrepo, Haehwan Park, Satish C. Muluk, Mark K. Eskandari, Seungik Baek, Ender A. Finol

“…NURBS enables the creation of continuous curves that seamlessly conform to the intricate contours of anatomical structures, offering a significant improvement in segmentation accuracy. …”
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ZSM-Based E2E Security Slice Management for DDoS Attack Protection in MEC-Enabled V2X Environments by Rodrigo Asensio-Garriga, Pol Alemany, Alejandro M. Zarca, Roshan Sedar, Charalampos Kalalas, Jordi Ortiz, Ricard Vilalta, Raul Munoz, Antonio Skarmeta

“…Security requirements are continuously monitored and, upon DDoS detection, our framework reacts with a coordinated E2E strategy. …”
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