Scurvy as a Cause of Leg Pain and Limp in Pediatric and Adolescent Patients by Christopher J. DeFrancesco, MD, David Kell, BA, Sean Owens, BS, Matt Grady, MD, Naomi Brown, MD

“…Key Concepts: (1) Scurvy, the condition caused by vitamin C deficiency, is not a historical disease, with research suggesting that its incidence in the US is on the rise. (2) Scurvy can result in lower extremity pain and limping among children, who may present for orthopaedic evaluation. (3) An increased index of suspicion for vitamin C deficiency should be maintained for any child with a history of restrictive eating, especially those with a history of autism spectrum disorder. (4) Orthopaedic providers should know the specific MRI and x-ray findings characteristic of vitamin C deficiency. (5) Vitamin C levels can be repleted in weeks with proper supplementation, but children with scurvy due to restrictive eating generally require continued intervention from nutrition and/or feeding specialists.…”
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Study of Long-term Spectral Evolution and X-Ray and γ-Ray Correlation of Blazars Seen by HAWC by R. Alfaro, C. Alvarez, A. Andrés, J.C. Arteaga-Velázquez, D. Avila Rojas, H.A. Ayala Solares, R. Babu, E. Belmont-Moreno, A. Bernal, K.S. Caballero-Mora, T. Capistrán, A. Carramiñana, F. Carreón, S. Casanova, U. Cotti, J. Cotzomi, S. Coutiño de León, E. De la Fuente, D. Depaoli, N. Di Lalla, R. Diaz Hernandez, B.L. Dingus, M.A. DuVernois, M. Durocher, J.C. Díaz-Vélez, K. Engel, C. Espinoza, K.L. Fan, N. Fraija, S. Fraija, J.A. García-González, F. Garfias, A. Gonzalez Muñoz, M.M. González, J.A. Goodman, S. Groetsch, J.P. Harding, S. Hernández-Cadena, I. Herzog, D. Huang, F. Hueyotl-Zahuantitla, A. Iriarte, V. Joshi, S. Kaufmann, D. Kieda, A. Lara, W.H. Lee, J. Lee, H. León Vargas, J.T. Linnemann, A.L. Longinotti, G. Luis-Raya, K. Malone, O. Martinez, I. Martinez-Castellanos, J. Martínez-Castro, J.A. Matthews, P. Miranda-Romagnoli, J.A. Montes, E. Moreno, M. Mostafá, A. Nayerhoda, L. Nellen, M.U. Nisa, R. Noriega-Papaqui, N. Omodei, M. Osorio, Y. Pérez Araujo, E.G. Pérez-Pérez, C.D. Rho, D. Rosa-González, E. Ruiz-Velasco, H. Salazar, D. Salazar-Gallegos, A. Sandoval, M. Schneider, J. Serna-Franco, A.J. Smith, Y. Son, R.W. Springer, O. Tibolla, K. Tollefson, I. Torres, R. Torres-Escobedo, R. Turner, F. Ureña-Mena, E. Varela, L. Villaseñor, X. Wang, I.J. Watson, K. Whitaker, E. Willox, S. Yun-Cárcamo, H. Zhou, C. de León, HAWC collaboration, Abraham D. Falcone, Fredric Hancock

“…The HAWC Observatory collected 6 yr of extensive data, providing an ideal platform for long-term monitoring of blazars in the very high energy (VHE) band, without bias toward specific flux states. HAWC continuously monitors blazar activity at TeV energies, focusing on sources with a redshift of z ≤ 0.3, based on the Third Fermi-LAT Catalog of High-Energy sources. …”
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Oral dydrogesterone versus oral micronized progesterone in threatened miscarriage: protocol paper for a randomized controlled trial by Alka Kriplani, Gouri Shankar Kamilya, T Ramani Devi, Ashima Taneja, Amol Pawar, Gayathri Karthik Nagesh, Tapan Pattanaik, Tanusree Gupta, Mahima Jain, Monjori Mitra

“…A total of 304 eligible pregnant women aged 20–39 years, diagnosed with threatened miscarriage, will be enrolled during 5–12 weeks of gestation and randomized equally to receive either oral dydrogesterone (40 mg stat, followed by 10 mg three times a day) or oral micronized progesterone (200 mg two times a day) up to one week after stoppage of bleeding or if bleeding does not stop, then treatment will be continued till a maximum of 14 weeks of gestation (unless miscarriage is confirmed earlier or the investigator decides to prolong treatment for better outcome or if bleeding relapses). …”
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Automatic Segmentation of Abdominal Aortic Aneurysm From Computed Tomography Angiography Using a Patch-Based Dilated UNet Model by Merjulah Roby, Juan C. Restrepo, Haehwan Park, Satish C. Muluk, Mark K. Eskandari, Seungik Baek, Ender A. Finol

“…NURBS enables the creation of continuous curves that seamlessly conform to the intricate contours of anatomical structures, offering a significant improvement in segmentation accuracy. …”
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Comparison of three recent discrete stochastic inversion methods and influence of the prior choice by Juda, Przemysław, Straubhaar, Julien, Renard, Philippe

“…To assess the quality of the results, we propose a framework based on continuous ranked probability score (CRPS), which compares single true values with predictive distributions. …”
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Differentiating the Acceleration Mechanisms in the Slow and Alfvénic Slow Solar Wind by Yeimy J. Rivera, Samuel T. Badman, J. L. Verniero, Tania Varesano, Michael L. Stevens, Julia E. Stawarz, Katharine K. Reeves, Jim M. Raines, John C. Raymond, Christopher J. Owen, Stefano A. Livi, Susan T. Lepri, Enrico Landi, Jasper. S. Halekas, Tamar Ervin, Ryan M. Dewey, Rossana De Marco, Raffaella D’Amicis, Jean-Baptiste Dakeyo, Stuart D. Bale, B. L. Alterman

“…Instead, the solar wind continues to accelerate, and it cools far more slowly than a freely expanding adiabatic gas. …”
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Minute-cadence Observations of the LAMOST Fields with the TMTS. VI. Physical Parameters of Contact Binaries by Qiqi Xia, Xiaofeng Wang, Kai Li, Xiang Gao, Fangzhou Guo, Jie Lin, Cheng Liu, Jun Mo, Haowei Peng, Qichun Liu, Gaobo Xi, Shengyu Yan, Xiaojun Jiang, Jicheng Zhang, Cui-Ying Song, Jianrong Shi, Xiaoran Ma, Danfeng Xiang, Wenxiong Li

“…With the development of wide-field surveys, a large amount of data on short-period W UMa contact binaries have been obtained. Continuous and uninterrupted light curves as well as high-resolution spectroscopic data are crucial in determining the absolute physical parameters. …”
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Evaluating ChatGPT-4's performance on oral and maxillofacial queries: Chain of Thought and standard method by Kaiyuan Ji, Zhihan Wu, Jing Han, Guangtao Zhai, Guangtao Zhai, Jiannan Liu

“…ObjectivesOral and maxillofacial diseases affect approximately 3.5 billion people worldwide. With the continuous advancement of Artificial Intelligence technologies, particularly the application of generative pre-trained transformers like ChatGPT-4, there is potential to enhance public awareness of the prevention and early detection of these diseases. …”
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Myocardial functional recovery following durable ventricular assist device in children by Bhavikkumar Langanecha, Osami Honjo, Alyssa Power, Oshri Zaulan, Christoph Haller, Kristen George, Linda Fazari, Andrea Maurich, David Chiasson, Aamir Jeewa

“…Material and Methods: Retrospective, single-center study of pediatric patients who were supported with durable VADs, both intracorporeal continuous flow devices (CFD) and paracorporeal pulsatile flow devices (PFD), between 2004 and 2022. …”
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Forty years of HIV infection and AIDS in Taiwan: Reflection on the past and looking toward the future by Sung-Hsi Huang, Hsun-Yin Huang, Stephane Wen-Wei Ku, Po-Hsien Kuo, Kuan-Yin Lin, Guan-Jhou Chen, Chia-Chi Lee, Yen-Fang Huang, Chien-Ching Hung

“…Unprotected sex, particularly among men who have sex with men, continues to be the leading risk for HIV transmission after implementation of harm reduction program to control an outbreak of HIV infection among people who inject drugs that occurred in 2003–2007. …”
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Qualitative and quantitative characteristics of black patch trait in Oujiang color common carp by Ke Jing, Huifan Chen, Nusrat Hasan Kanika, Penghui Zhang, Roland Nathan Mandal, Chunxiao Zeng, Zhiyi Zhang, Jun Wang, Chenghui Wang

“…The coverage ratio of the black patches (CRB) in the hybrid was found continuous and nearly normal distribution. Compared with the parent RB, the sizes of melanocytes were significantly smaller, but the number of melanocytes was significantly higher in the hybrid. …”
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A qualitative study exploring depressed participants’ experiences of receiving Augmented Depression Therapy (ADepT) by Rebecca Watson, Kim A Wright, Nigel Reed, Barney Dunn, Emily Widnall, Kalliopi Demetriou, Laura Warbrick, Katie Marchant, Nicole Geschwind, Isabella Magner-Parsons, Rachel Barter

“…Perceived mechanisms of change were reorienting to the positive, engaging with valued goals, taking a proactive life stance, gaining confidence and motivation for change, breaking down tasks into small steps, cultivating self-care and self-compassion, enhancing help seeking and interpersonal effectiveness, changing the relationship to depression, and rediscovering the self beyond depression.Conclusions Findings suggest that the wellbeing focus of ADepT is acceptable and leads to positive impacts, supports the logic model underpinning the intervention, and warrants continuation to a definitive trial.Trial registration number ISRCTN85278228.…”
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Development of High Dietary Fiber Cereal Bar as Emergency Food Product and The Chemical-Microbiological Properties and Nutritional Content by Ani Radiati, Sumarto Sumarto, Fahmi Hafid, Emma Kamelia, Lia Nurcahyani, Dini Mariani, Siti Badriah, Tjahja Muhandri

“…Its high fiber content and lack of harmful contaminants make it safe and nutritious for disaster victims. Continued testing and development with diverse flavors and formulations are recommended to improve acceptance across age groups in emergency situations.…”
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Dynamic recrystallization and mechanical behavior of Mg alloy AZ31: Constraints from tensile tests with in-situ EBSD analysis by Boissonneau, Gaëtan, Tommasi, Andréa, Barou, Fabrice, Lopez-Sanchez, Marco Antonio, Montagnat, Maurine

“…Both in-situ microstructural observations and statistical analysis of microstructural properties document continuous DRX with nucleation by association of bulging and subgrain rotation starting at strains as low as 6%. …”
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Observations of Loki Patera by Juno during Close Flybys by Alessandro Mura, Rosaly M. C. Lopes, Federico Tosi, Francesca Zambon, Roberto Sordini, Peter J. Mouginis-Mark, Julie Rathbun, Scott Bolton, Jani Radebaugh, Alberto Adriani, Andrea Cicchetti, Davide Grassi, Melissa Mirino, Raffaella Noschese, Giuseppe Piccioni, Christina Plainaki, Giuseppe Sindoni

“…Loki shows a thermal structure unlike other active lava lakes previously reported, with some brightening near the lake’s perimeter but lacking the continuous “hot ring” seen at other paterae. Modeling the slow rate of cooling suggests there is a significant volume of magma beneath the crust to provide the latent heat necessary to decelerate the cooling. …”
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The maternal and newborn health eCohort to track longitudinal care quality: study protocol and survey development by Catherine Arsenault, Katherine Wright, Tefera Taddele, Ashenif Tadele, Anagaw Derseh Mebratie, Firew Tiruneh Tiyare, Rose J. Kosgei, Jacinta Nzinga, Bethany Holt, Irene Mugenya, Emma Clarke-Deelder, Adiam Nega, Dorairaj Prabhakaran, Sailesh Mohan, Nompumelelo Gloria Mfeka-Nkabinde, Londiwe Mthethwa, Damen Haile Mariam, Gebeyaw Molla, Theodros Getachew, Prashant Jarhyan, Monica Chaudhry, Munir Kassa, Margaret E. Kruk

“…The final MNH eCohort instrument is centered around six key domains of high-quality health systems including competent care (content of ANC, delivery, and postnatal care for the mother and newborn), competent systems (prevention and detection, timely care, continuity, integration), user experience, health outcomes, confidence in the health system, and economic outcomes. …”
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CD8+T cells and monocytes were associated with brain alterations in human immunodeficiency virus-infected individuals with cognitive impairment by Xin Zhang, Zhen Li, Jiahao Ji, Yundong Ma, Guangqiang Sun, Xue Chen, Ling Zhang, Tong Zhang, Yulin Zhang, Yang Zhang

“…Cognitive impairment (CI) continues to be a concern for people living with HIV-1 (PLWH) in the era of antiretroviral therapy (ART), yet the underlying mechanisms remain unclear. …”
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Long-Term Results of the Etiotropic Therapy of Subcompensed Liver Cirrhosis in the Outcome of Chronic Hepatitis C by P. O. Bogomolov, A. O. Bueverov, V. E. Bakirova, E. O. Lyusina, E. A. Fedosyina, S. V. Koblov, O. V. Sumtsova

“…Longterm follow-up results indicate a significant improvement of liver function, but also a continuing high risk of developing complications of underlying disease, primarily HCC.…”
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Targeting transforming growth factor-β1 by methylseleninic acid/seleno-L-methionine in clear cell renal cell carcinoma: Mechanisms and therapeutic potential by Aseel O. Rataan, Yan Xu, Sean M. Geary, Yousef Zakharia, Eman S. Kamel, Youcef M. Rustum, Aliasger K. Salem

“…Clear cell renal cell carcinoma (ccRCC) poses a significant global health challenge as its incidence continues to rise, resulting in a substantial annual mortality rate. …”
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A study on the differences in the gut microbiota and metabolism between male and female mice in different stress periods by Yajun Qiao, Yajun Qiao, Yajun Qiao, Juan Guo, Qi Xiao, Jianv Wang, Jianv Wang, Xingfang Zhang, Xingfang Zhang, Xinxin Liang, Xinxin Liang, Lixin Wei, Lixin Wei, Hongtao Bi, Tingting Gao, Tingting Gao

“…After 14 days of stress withdrawal, the depression-like behavior continued to worsen in female mice, and the levels of 5α-pregnane-3,20-dione, estrone glucuronide and f-Erysipelotrichaceae were significantly different from those in male mice. …”
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