Real world study on combining local interventions with systemic therapy in unresectable hepatocellular carcinoma by Zhaosong Xue, Ming Yao, Kang Chen, Taiyun Huang, Jianjun Li, Jian Chen, Fei Huang, Yubin Huang, Xiaoyong Cai, Yihe Yan

“…Other independent risk factors related to overall survival contained extrahepatic metastasis (HR, 2.152; 95% CI, 1.076–4.302; P = 0.030), tumor number ≥ 4 (HR, 2.058; 95% CI, 1.001–4.234; P = 0.049) and radiological remission (HR, 0.233; 95% CI, 0.071–0.768; P = 0.017). …”
Get full text

The effect of Ocimum basilicum on the prevention of postpartum depression symptoms and sleep quality: A triple-blind randomized controlled clinical trial by Monireh Abdi, Elham Rezaei, Mojgan Mirghafourvand, Fatemeh Ebrahimi, Laleh Payahoo, Alireza Shafiei-Kandjani, Solmaz Ghanbari-Homaie

“…The intervention group received two daily capsules containing dried basil leaf powder, while the control group received 500 mg of starch. …”
Get full text

Thermal radiation effects of ternary hybrid nanofluid flow in the activation energy: Numerical computational approach by Hakeem Ullah, Syed Arshad Abas, Mehreen Fiza, Aasim Ullah Jan, Ali Akgul, Magda Abd El-Rahman, Seham M. Al-Mekhlafi

“…Purpose: This study introduces a novel investigation into heat transport phenomena of ternary hybrid, hybrid and nanofluid containing copper, silver and alumina nanoparticles within two stretchy rotating disks maintaining a constant distance. …”
Get full text

Investigating the potential immunomodulatory effects of commercial oral probiotic supplements on equine gastrointestinal tract barrier function by Agnieszka Żak-Bochenek, Paulina Żebrowska-Różańska, Joanna Bajzert, Łukasz Łaczmański, Bogumiła Szponar, Natalia Siwińska, Klaudia Gładysz, Katarzyna Sikorska, Anna Chełmońska-Soyta

“…Such a study has not yet been conducted in horses.MethodsThis study involved 12 healthy horses, which were randomly divided into a control group and a group that received a commercial oral probiotic formula containing Lactobacillus rhamnosus, Pedioccus acidilactici or Enterococcus faecium for 84 days. …”
Get full text

PDZRN3 regulates adipogenesis of mesenchymal progenitors in muscle by Hiroki Iida, Minako Kawai-Takaishi, Yoshihiro Miyagawa, Yasuhiko Takegami, Akiyoshi Uezumi, Takeshi Honda, Shiro Imagama, Tohru Hosoyama

“…Recently, we found that PDZ domain-containing ring finger 3 (PDZRN3), an E3-ubiquitin ligase, was highly expressed in MPs. …”
Get full text

Characterization and Probiotic Potential of <i>Levilactobacillus brevis</i> DPL5: A Novel Strain Isolated from Human Breast Milk with Antimicrobial Properties Against Biofilm-Formi... by Ivan Iliev, Galina Yahubyan, Elena Apostolova-Kuzova, Mariyana Gozmanova, Daniela Mollova, Iliya Iliev, Lena Ilieva, Mariana Marhova, Velizar Gochev, Vesselin Baev

“…Furthermore, genome-wide sequencing and analysis of <i>L. brevis</i> DPL5 with cutting-edge Nanopore technology has uncovered over 50 genes linked to probiotic activity, supporting its ability to adapt and thrive in the harsh gut environment. The genome also contains multiple biosynthetic gene clusters such as lanthipeptide class IV, Type III polyketide synthase (T3PKS), and ribosomally synthesized, and post-translationally modified peptides (RiPP-like compounds), all of which are associated with antibacterial properties. …”
Get full text

Impact of meropenem exposure on fluoroquinolone and carbapenem resistance in Pseudomonas aeruginosa infection in inpatients in a Japanese university hospital: Insights into oprD mu... by Tadanori Yamochi, Kazuhisa Ugajin, Rintaro On, Sho Inoue, Hiromi Ikeda, Toshiko Yamochi, Masafumi Takimoto, Issei Tokimatsu

“…Additionally, seven of eight dual fluoroquinolone and carbapenem-resistant isolates carried a premature termination codon within oprD, containing either F170L or L7 shortening. Conclusions: In dual fluoroquinolone- and carbapenem-resistant P. aeruginosa, alterations in the OprD porin and the presence of an active EP are primary resistance mechanisms. …”
Get full text

Nanoliposomal L-Asparaginase and Its Antitumor Activities in Lewis Lung Carcinoma Tumor-Induced BALB/c Mice by Thi Thao Do, Thi Phuong Do, Thi Nga Nguyen, Thi Cuc Nguyen, Thi Thu Phuong Vu, Thi Giang An Nguyen

“…The average size of the liposomes containing purified L-asparagine was 93.03 ± 0.49 nm. …”
Get full text

Silicon-based all-solid-state batteries operating free from external pressure by Zhiyong Zhang, Xiuli Zhang, Yan Liu, Chaofei Lan, Xiang Han, Shanpeng Pei, Linshan Luo, Pengfei Su, Ziqi Zhang, Jingjing Liu, Zhengliang Gong, Cheng Li, Guangyang Lin, Cheng Li, Wei Huang, Ming-Sheng Wang, Songyan Chen

“…Under the cold-pressed sintering of Li21Si5 alloys, the anode forms a top layer (Li21Si5 layer) with mixed ionic/electronic conduction and a bottom layer (Si–Li21Si5 layer) containing a three-dimensional continuous conductive network. …”
Get full text

Sustainability index analysis of microalgae cultivated in biorefinery palm oil mill effluent by A. Santoso, T. Handayani, D. Pinardi, K. Kusrestuwardani, N. Widyastuti, I. Djarot, J. Haryanti, A. Sitomurni, H. Apriyanto

“…BACKGROUND AND OBJECTIVES: Palm oil mill effluent is a liquid waste produced at a palm oil mill industry during the production process containing abundant organic pollutants such as nitrogen and phosphorus that will be harmful to the environment. …”
Get full text

Unveiling the prognostic value of ARID3A in breast cancer through bioinformatic analysis by Wen-Run Cai, Xu-Gang Sun, Yue Yu, Xin Wang, Xu-Chen Cao, Xiao-Feng Liu

“…Recent studies highlight the AT-rich interactive domain-containing protein (ARID) family, particularly ARID3A, as influential in cancer progression, though its specific role in breast cancer remains unclear. …”
Get full text

PretoxTM: a text mining system for extracting treatment-related findings from preclinical toxicology reports by Javier Corvi, Nicolás Díaz-Roussel, José M. Fernández, Francesco Ronzano, Emilio Centeno, Pablo Accuosto, Celine Ibrahim, Shoji Asakura, Frank Bringezu, Mirjam Fröhlicher, Annika Kreuchwig, Yoko Nogami, Jeong Rih, Raul Rodriguez-Esteban, Nicolas Sajot, Joerg Wichard, Heng-Yi Michael Wu, Philip Drew, Thomas Steger-Hartmann, Alfonso Valencia, Laura I. Furlong, Salvador Capella-Gutierrez

“…Much of this information is contained in toxicology reports, which summarise the results of animal studies designed to analyse the effects of the tested compound, including unintended pharmacological and toxic effects, known as treatment-related findings. …”
Get full text

Mitophagy mediated by HIF-1α/FUNDC1 signaling in tubular cells protects against renal ischemia/reperfusion injury by Wenjun Zhang, Chao Guo, Yi Li, Hao Wang, Huabing Wang, Yingying Wang, Tingting Wu, Huinan Wang, Gang Cheng, Jiangwei Man, Siyu Chen, Shengjun Fu, Li Yang

“…Moreover, H/R treatment enhanced expression of the FUN14 domain-containing 1 (FUNDC1) protein. Additionally, FUNDC1 overexpression reversed the effects of LW6 on the altered expression of light chain 3 (LC3) BII and voltage-dependent anion channels as well as blocked the effects of HIF-1α inhibition in cells. …”
Get full text

Malva neglecta essential oil: A promising approach for bio-preserving mayonnaise and assessing variable correlations through principal component analysis and heat map by Amin Abbasi, Hedayat Hosseini, Hadi Pourjafar, Samaneh Moradi, Saeedeh Shojaee-Aliabadi

“…Based on the determined MIC/MBC, various concentrations of MNEO have been utilized in the preparation of mayonnaise and evaluated for microbial, chemical, and sensorial characteristics for 40 days at 4 °C. MNEO contains podocarpa-8,11,13-trien-3-one, 12-hydroxy-13-isopropyl, δ-elemene, γ-elemene, bicyclogermacrene, β-ylangene, viridiflorol, spathulenol, 6,10,14-trimethyl-2-pentadecanone, L-linalool, γ-curcumene, germacrene D, n-tetradecane, β-elemene, β-damascenone, δ-cadinene, α-muurolol, cis-muurola-3,5-diene, and α-cadinol with substantial antibacterial and antioxidant properties. …”
Get full text

Isolation, Identification, and Pathogenicity of Potential Probiotics Isolated from Intestinal Coconut Crab (Birgus latro Linnaeus, 1767) by Muhammad Aris, Tamrin Tamrin, Waode Munaeni, Sudirto Malan, Juharni Juharni, Rusmawati Labenua

“…The scouring liquid was taken in 0.1 ml and spread on a petri dish containing Nutrient Agar. The isolated used were marked with BL1, BL2, BL3, BL4, and BL5. …”
Get full text

Isolation of competent actinomycetes strains from soil planted with three species of mint irrigated with olive mill wastewater by Oumaima Beroigui, Lahsen El Ghadraoui, Faouzi Errachidi

“…Results: Analysis revealed that OMWW contained high levels of organic matter and mineral salts, resulting in elevated chemical oxygen demand and salinity. …”
Get full text

Assessment of Protein Quality and Nutritional Characteristics of Commonly Consumed Pulses in the Caribbean Diet by Different In Vitro Assays by Daniel J. Thomas, Zhanhui Lu, Yolanda Brummer, Yan Zhu, Ronghua Liu, Lili Mats, Rong Tsao, D. Dan Ramdath, Matthew G. Nosworthy

“…Protein quality, determined via three in vitro protein digestibility methods, starch, and phenolic content were determined in pre- and post-cooked samples using established methods. Pulses contained 20–26% protein, and cooking improved protein digestibility on average by 14.0 ± 2.5% (<i>p</i> < 0.05). …”
Get full text

Image depth estimation assisted by multi-view projection by Liman Liu, Jinshan Tian, Guansheng Luo, Siyuan Xu, Chen Zhang, Huaifei Hu, Wenbing Tao

“…The depth estimation network with single-view input can only extract features from a single 2D image, often neglecting the information contained in neighboring views, resulting in learned features that lack real geometrical information in the 3D world and stricter constraints on the 3D structure, leading to limitations in the performance of image depth estimation. …”
Get full text

Genomic regions of Solanum tuberosum L. associated with the tuber eye depth by I. V. Totsky, I. V. Rozanova, A. D. Safonova, A. S. Batov, Yu. A. Gureeva, A. V. Kochetov, E. K. Khlestkina

“…The results of localization in the region 48.1–48.9 Mb of chromosome 10 correspond to previously published studies, the remaining three regions were detected for the first time. DNA sections containing SNPs linked to the tuber’s eye depth were studied in the SolTub_3.0 potato genome assembly (https:// plants.ensembl.org/). …”
Get full text

Accumulation conditions and target area evaluation of coalbed methane in eastern uplift of Junggar Basin by Qixiang YU, Mi TIAN, Yu LUO, Fan YANG, Yan'e CHEN, Feng WANG, Yuqiao GAO, Tao GUO

“…Coal seams of the Badaowan Formation are strongly segmented and mainly distributed in parts of the sags. ② This region contains self-sourced biogenic gas from coal seams, low-maturity thermogenic gas, and high-maturity deep-seated exogenous gas. ③ The organic components in coal rocks are mainly inertinite, followed by vitrinite with small amounts of exinite. …”
Get full text