Quercetin attenuates cisplatin-induced fatigue through mechanisms associated with the regulation of the HPA axis and MCP-1 signaling by Cheng-Hung Chuang, Yu-An Tai, Ting-Jing Wu, Ying-Jui Ho, Shu-Lan Yeh, Shu-Lan Yeh

“…The main objective of the present study was to investigate whether quercetin regulates the hypothalamic-pituitary-adrenal (HPA) axis and chemoattractant protein-1 (MCP-1) signaling, two factors contributing to CRF in mice exposed to cisplatin.MethodsMale BALB/c mice were randomly assigned to the following five groups for 15 weeks: Control, CDDP, CDDP+TAK779 (an antagonist of MCP-1 receptor, human CC chemokine receptor R2 (CCR2)), CDDP+OQ (a diet containing 1% quercetin) and CDDP+IQ (quercetin given by ip, 10 mg/kg, 3 times/week).ResultsThe results first showed that OQ and IQ significantly increased grip strength and locomotor activity, decreased plasma cortisol/corticosterone levels, and decreased the corticotropin releasing hormone (CRH) mRNA level in the brain tissues in mice exposed to CDDP. …”
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Nomenclatural standards for the spring oat cultivars (<i>Avena sativa</i> L.) developed in the Urals and Siberia by I. V. Varganova, V. Е. Kardashina, L. V. Bessonova, R. I. Vyatkina, N. V. Lebedeva

“…Each herbarium sheet contains the entire plant in the state of milky ripeness, as well as mature spikes and grains.Results and conclusion. …”
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A Promising Approach to Ultra‐Flexible 1 Ah Lithium–Sulfur Batteries Using Oxygen‐Functionalized Single‐Walled Carbon Nanotubes by Junyoung Heo, Jeong‐Won Hong, Ha Won Gu, Junghwan Sung, Dong‐Hee Kim, Jung Hoon Kim, Sung Kang, You‐Jin Lee, Hye Young Choi, Doohun Kim, Kang‐Jun Baeg, Joong Tark Han, Jun‐Woo Park

“…Additionally, oxygen‐containing functional groups on the SWCNTs significantly improve electrochemical performance by promoting the adsorption of lithium polysulfides. …”
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Angiogenic Potential of Human Neonatal Foreskin Stromal Cells in the Chick Embryo Chorioallantoic Membrane Model by Radhakrishnan Vishnubalaji, Muhammad Atteya, May Al-Nbaheen, Richard O. C. Oreffo, Abdullah Aldahmash, Nehad M. Alajez

“…CAMs transplanted with endothelial-differentiated hNSSCs displayed a higher number of blood vessels containing hNSSCs compared to CAMs transplanted with undifferentiated hNSSCs. …”
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Addition of basil leaf (Ocimum basicilum L.) extract to AndroMed® extender improved the quality of spermatozoa of frozen thawed Simmental bull semen by Aditya Irawan, Fajar Ramadhan Subiyantoro, Suherni Susilowati, Tri Wahyu Suprayogi, Sri Pantja Madyawati, Pudji Srianto, Nove Hidajati, Eduardus Bimo Aksono Herupradoto, Kadek Rachmawati

“…Ejaculate that met the motility qualification of more than 70%, was divided into three groups, each extended in AndroMed® without the addition of basil leaf extract (T0), with the addition of 0.1% basil leaf extract (T1) and with the addition of 0.3% basil leaf extract (T2). Straw containing semen with 30 million spermatozoa/straw was processed using an IceCube automatic freezer (Minitube, Germany). …”
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The Role of Glucocorticoid Receptors in Dexamethasone-Induced Apoptosis of Neuroprogenitor Cells in the Hippocampus of Rat Pups by Chun-I Sze, Yung-Chieh Lin, Yuh-Jyh Lin, Ting-Hui Hsieh, Yu Min Kuo, Chyi-Her Lin

“…Since the hippocampus contains a high density of glucocorticoid receptors (GCRs), we hypothesized that Dex affects neurogenesis in the hippocampus through inflammatory mediators. …”
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Dynamics of blackleg epizootic process in the Republic of Kazakhstan by A. Abutalip, B. D. Aitzhanov, A. K. Mussayeva, V. Yu. Sushchikh, N. N. Yegorova, Ye. K. Ospanov, M. A. Berdikulov, K. A. Kalkabayev, N. Matikhan

“…Within the mentioned period, the average number of blackleg-infected animals per one outbreak ranged between1 and 3 animals, which proves that blackleg is anon-contagious disease. The research indicates that blackleg is a seasonal disease in the Republic of Kazakhstan with an incidence rise in autumn. …”
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Use of Hybrid Flame Retardants in Chemically Foamed rPET Blends by Veronika Anna Szabó, Sándor Kálmán Jakab, András Kovács, Tamara Zsuzsanna Böcz, Gábor Dogossy

“…Three different kinds of halogen-free flame retardant agents were used: ammonium polyphosphate-based Exolit AP 422 (AP), organic aluminum phosphate in the form of Exolit OP 1240 (OP), and Budit 342 containing melamine polyphosphate (MPP). The hybrid flame retardant mixture, by combining the swelling and charring mechanism, increased the flame retardancy of the samples. …”
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Dataset of speech produced with delayed auditory feedbackOpen Science FrameworkOpen Science Framework by Matthias Heyne, Monique C. Tardif, Alexander Ocampo, Ashley P. Petitjean, Emily J. Hacker, Caroline N. Fox, Megan A. Liu, Madeline Fontana, Vincent Pennetti, Jason W. Bohland

“…To our knowledge, there are currently no publicly available research datasets containing recordings of speech produced with DAF. Here we describe a large dataset of speech produced with DAF using modern experimental methods with systematic controls and varied speaking materials, including phonotactically legal, nonword syllable sequences and American English sentences. …”
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Role of the androgen receptor in melanoma aggressiveness by Marzia Di Donato, Costanza Maria Cristiani, Mariaelena Capone, Cinzia Garofalo, Gabriele Madonna, Lucia Carmela Passacatini, Margaret Ottaviano, Paolo Antonio Ascierto, Ferdinando Auricchio, Ennio Carbone, Antimo Migliaccio, Gabriella Castoria

“…Novel therapies targeting receptor tyrosine kinases, kinases and immune checkpoints have been employed with a significant improvement of the overall survival and long-term disease containment. Nevertheless, the disease often progresses and becomes resistant to the therapies. …”
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Effectively alleviate rheumatoid arthritis via maintaining redox balance, inducing macrophage repolarization and restoring homeostasis of fibroblast-like synoviocytes by metformin-... by Rui Zhang, Xingyu Lin, Rongjie Lin, Zhenbin Chen, Chenfang Miao, Yao Wang, Xiaoqin Deng, Jianlong Lin, Shishui Lin, Shaohuang Weng, Min Chen

“…In addition, MCDs eliminated the cellular ROS in M1 phenotype macrophages in RA microenvironment through the enzyme-like catalytic activity as well as inhibiting NOD-like receptor family, pyrin domain containing 3 (NLRP3) inflammasome signaling pathway, effectively polarizing them into the M2 phenotype to realize the anti-inflammatory effect. …”
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Influence of Gd alloying and ultrasonic vibration hybrid treatment on the microstructures, mechanical properties and strengthening mechanisms of Al/Mg interface by compound casting by Qingqing Li, Wenming Jiang, Yuancai Xu, Linghui Yu, Ziwei Peng, Yunchang Xin, Zitian Fan

“…The coherent relationships among Mg2Si, Al12Mg17 and δ-Mg as well as the Gd contained precipitates and Al12Mg17 were revealed. …”
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Improving the Reporting of Primary Care Research: Consensus Reporting Items for Studies in Primary Care—the CRISP Statement by Phillips William R., Sturgiss Elizabeth, Glasziou Paul, olde Hartman Tim C., Orkin Aaron M., Prathivadi Pallavi, Reeve Joanne, Russell Grant M., van Weel Chris

“…The CRISP Checklist contains 24 items that describe the research team, patients, study participants, health conditions, clinical encounters, care teams, interventions, study measures, settings of care, and implementation of findings/results in PC. …”
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Ultrahigh piezoelectric performances of (K,Na)NbO3 based ceramics enabled by structural flexibility and grain orientation by Li-Feng Zhu, Dong Liu, Xiaoming Shi, Shiqing Deng, Jiecheng Liu, Li-Yu Wei, Zi-Qi Yang, Qi Wang, Bo-Ping Zhang, Houbing Huang, Shujun Zhang, Jing-Feng Li

“…Abstract (K,Na)NbO3-based ceramics are deemed among the most promising lead-free piezoelectric materials, though their overall piezoelectric performance still lags behind the mainstream lead-containing counterparts. Here, we achieve an ultrahigh piezoelectric charge coefficient d33 ∼ 807 pC·N−1, along with a high longitudinal electromechanical coupling factor (k33 ∼ 88%) and Curie temperature (Tc ∼ 245 °C) in the (K,Na)(Nb1-x Sb x )O3-Bi0.5Na0.5ZrO3-BiFeO3 (KNN-xSb) system through structural flexibility and grain orientation strategies. …”
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Recovery of Bioactive Constituents from Olive Leaf Pruning Waste of Five Different Cultivars: A Comparison of Green Extraction Techniques to Maximize Health Benefits by Hamid Mushtaq, Simona Piccolella, Jose A. Mendiola, Lidia Montero, Elena Ibáñez, Severina Pacifico

“…PLE extracts showed better antiradical activities, putatively due to a higher content of flavonoids, secoiridoids, and HCA derivatives than UAM-EtOH ones, as these latter also contained 20–40% (cultivar-dependent) of triterpenes. …”
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Novel (Q)SAR models for prediction of reversible and time-dependent inhibition of cytochrome P450 enzymes by Sadegh Faramarzi, Arianna Bassan, Kevin P. Cross, Xinning Yang, Glenn J. Myatt, Donna A. Volpe, Lidiya Stavitskaya

“…The non-proprietary training database for the QSAR models contains data for 10,129 chemicals harvested from FDA drug approval packages and published literature. …”
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Complete genome sequence of Pseudarthrobacter sp. NIBRBAC000502770 from coal mine of Hongcheon on Republic of Korea by Min-Kyu Park, Yeong-Jun Park, Myung-Suk Kang, Min-Ha Kim, Soo-Young Kim, Jae-Ho Shin

“…NIBRBAC000502770, isolated from the rhizosphere of Sasamorpha in a heavy metal-contaminated coal mine in Hongcheon, Republic of Korea. …”
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A Study to Inform the Design of a National Multicentre Randomised Controlled Trial to Evaluate If Reducing Serum Phosphate to Normal Levels Improves Clinical Outcomes including Mor... by Ramya Bhargava, Philip A. Kalra, Paul Brenchley, Helen Hurst, Alastair Hutchison

“…Dual centre prospective parallel group study: 100 dialysis patients randomized to lower (phosphate target 0.8 to 1.4 mmol/L) or higher range group (1.8 to 2.4 mmol/L). Non-calcium-containing phosphate binders and questionnaires will be used to achieve target phosphate. …”
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2-Aminothiophene Derivatives—New Drug Candidates Against Leishmaniasis: Drug Design, Synthesis, Pharmacomodulation, and Antileishmanial Activity by Rodrigo Santos Aquino de Araújo, Vitória Gaspar Bernardo, Robert da Silva Tibúrcio, Danilo Cesar Galindo Bedor, Michel Leandro de Campos, Roberto Pontarolo, Julyanne Maria Saraiva de Sousa, Klinger Antonio da Franca Rodrigues, Marcus Tullius Scotti, Anuraj Nayarisseri, Pascal Marchand, Francisco Jaime Bezerra Mendonça-Junior

“…<b>Background/Objectives</b>: Leishmaniasis is one of the 20 Neglected Tropical Diseases according to the WHO, affecting approximately 12 million people in four continents, generating serious public health problems. …”
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A Hybrid Framework for Detection and Analysis of Leaf Blight Using Guava Leaves Imaging by Sidrah Mumtaz, Mudassar Raza, Ofonime Dominic Okon, Saeed Ur Rehman, Adham E. Ragab, Hafiz Tayyab Rauf

“…Guava is a common fruit found in different countries. It is considered the fourth primary fruit in Pakistan. …”
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