LC-MS/MS Method for Simultaneous Quantification of Dexmedetomidine, Dezocine, and Midazolam in Rat Plasma and Its Application to Their Pharmacokinetic Study by Wenjuan Cui, Qin Liu, Shan Xiong, Lujun Qiao

“…Chromatographic separation was achieved on a C18 column (50 mm × 2.1 mm, 3 µm) using a mobile phase composed of water (containing 0.1% formic acid) and acetonitrile. The lower limits of quantification were 0.1, 0.1, and 0.2 ng/mL for dexmedetomidine, dezocine, and midazolam in rat plasma, respectively. …”
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Predation, reoccupation, cannibalism, and scavenging? Records of small mammals in arctic ground squirrel middens from east Beringia by Scott L. Cocker, Grant D. Zazula, Elizabeth Hall, Christopher N. Jass, John E. Storer, Duane G. Froese

“…Two temporally distinct populations of U. parryii middens were identified from middens in association with Dawson tephra (~30,000 yr B.P.) and Sheep Creek Klondike tephra (~80,000 yr B.P.) containing the remains of arctic ground squirrels, voles (Microtus sp. …”
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Osteoarthritic Synovial Fluid Modulates Cell Phenotype and Metabolic Behavior In Vitro by Eduardo Branco de Sousa, Gilson Costa dos Santos Junior, Ramon Pinheiro Aguiar, Rafaela da Costa Sartore, Ana Carolina Leal de Oliveira, Fabio Ceneviva Lacerda Almeida, Vivaldo Moura Neto, Diego Pinheiro Aguiar

“…Then, we performed a MTT assay exposing SF cells from non-OA and OA patients to a medium containing non-OA and OA synovial fluid. Synovial fluid from non-OA and OA patients was submitted to ELISA to evaluate BMP-2, BMP-4, IL-6, IL-10, TNF-α, and TGF-β1 concentrations and to a metabolomic evaluation using 1H-NMR. …”
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Lipid Nanoparticles With Fine‐Tuned Composition Show Enhanced Colon Targeting as a Platform for mRNA Therapeutics by Riccardo Rampado, Gonna Somu Naidu, Olga Karpov, Meir Goldsmith, Preeti Sharma, Assaf Ezra, Lior Stotsky, Dor Breier, Dan Peer

“…Compared to LNPs with benchmark composition (b‐LNPs), n‐LNPs containing 30% distearoylphosphatidylcholine (DSPC) are well tolerated following intravenous administration and display natural targeting toward the inflamed colon in dextran sodium sulfate (DSS)‐colitis bearing mice, while de‐targeting clearing organs such as the liver and spleen. …”
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Physicochemical properties of water quality of Imeh, Edegelem and Chokocho communities located along Otamiri-oche River in Etche Ethnic Nationality of Rivers State, Nigeria by BM Onyegeme-Okerenta, C Obia, MO Wegwu

“…The results of bacteriological study showed that all the sampling locations contained high numbers of coliform bacteria in both rainy and dry seasons. …”
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Concrete reinforcement using composite fiberglass-based materials by Benzerga Ahmed Lamine, Amieur Mohamed, Rabehi Rachid

“…Additionally, these composite materials can be utilized for column containment as well as shear and bending reinforcement for beams. …”
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Exploring the multifaceted roles of Sonneratia apetala and Nipa fruticans in coastal habitat restoration and bioactive properties discovery by Sabina Yasmine, Rezwana Zaman Proma, Md. Ripaj Uddin, Mohammad Saydur Rahman, Md. Hamedul Islam, Muhammad Abdullah Al Mansur, AHM Shofiul Islam Molla Jamal, Abu Yousuf, Md. Hasnain Mustak, Sarker Kamruzzaman, M. Mahboob Ali Siddiqi

“…The pericarp, though lower in these compounds, still presents significant nutritional value, containing 55.4 mg GAE/g polyphenols and 14.6 mg CE/g flavonoids. …”
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Failure behaviors of anisotropic shale with a circular cavity subjected to uniaxial compression by Xianhui Feng, Huilin Liu, Peitao Wang, Shichao Zhang, Quanqi Zhu, Chun'an Tang, Yaxing Leng

“…In this study, a uniaxial compression test was performed on shale specimens containing a circular hole to investigate the effects of layer inclination and circular holes on the mechanical properties, elastic energy storage, and failure behaviors of these specimens. …”
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Enhancement of Mechanical and Thermal Properties of Poly(L-lactide) Nanocomposites Filled with Synthetic Layered Compounds by Telma Nogueira Caio, Núria Gonçalves, Fernando Wypych, Liliane Maria Ferrareso Lona

“…PLLA nanocomposites containing two different fillers concentrations (1 wt% and 2 wt%) were produced. …”
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The Significance of the 2014 Corporate Governance Code of the Bank of Russia by A. V. Shashkova

“…Compliance is a system based on binding rules of conduct contained in the regulations which are mandatory for the company. …”
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Rubric Design: A Designer’s Perspective by William Furman

“…If you ever have designed rubrics, you know well they resolve some issues but present many more. They contain a conundrum of specific questions: What do I want my students to know? …”
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Multi-hop wireless network oriented multiple jammers localization algorithm by Qi-ping WANG, Xiang-lin WEI, Jian-hua FAN, Tong-xiang WANG, Fei HU

“…The proposed algo-rithm contained three steps, packet delivery ratio (PDR) valley point determination based on gradient descent algorithm, received jamming signal strength (RJSS) peak point determination based on gradient ascent algorithm and cluster analysis. …”
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Research on the scalability of parallel community detection algorithms by Qiang LIU, Yan JIA, Binxing FANG, Bin ZHOU, Yue HU, Jiuming HUANG

“…The social network often contains a large amount of information about users and groups,such as topic evolution mode,group aggregation effect,the law of information dissemination and so on.The mining of these information has become an important task for social network analysis.As one characteristic of the social network,the group aggregation effect is characterized by the community structure of the social network.The discovery of community structure has become the basis and key point of other social network analysis tasks.With the rapid growth of the number of online social network users,the traditional community detection methods have been difficult to be used,which contributes to the development of parallel community detection technology.The current mainstream parallel community detection methods,including Louvain algorithm and label propagation algorithm,were tested in the large-scale data sets,and corresponding advantages and disadvantages were pointed out so as to provide useful information for later applications.…”
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Characterization and genomic insights into bacteriophages Kpph1 and Kpph9 against hypervirulent carbapenem-resistant Klebsiella pneumoniae by Ye Huang, Yuan Huang, Zhiping Wu, Ziyue Fan, Fanglin Zheng, Yang Liu, Xinping Xu

“…Interestingly, both phages have been found to contain two tail fiber proteins that may exhibit potential depolymerase activities. …”
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One-Step Synthesis of TiO2/Perlite Composites by Flame Spray Pyrolysis and Their Photocatalytic Behavior by M. Giannouri, Th. Kalampaliki, N. Todorova, T. Giannakopoulou, N. Boukos, D. Petrakis, T. Vaimakis, C. Trapalis

“…Precursor TIPO-ethanol solutions containing homogeneously dispersed perlite particles were processed through FSP setup at different experimental conditions regarding the gas flow and precursor supply rates. …”
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Image Sequence Fusion and Denoising Based on 3D Shearlet Transform by Liang Xu, Junping Du, Zhenhong Zhang

“…In general, the most existing image fusion methods only consider combining the important information of source images and do not deal with the artifacts. If source images contain noises, the noises may be also transferred into the fusion image together with useful pixels. …”
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Alternative splicing for tuneable expression of protein subunits at desired ratios by Christel Aebischer-Gumy, Pierre Moretti, Timothee Brunstein Laplace, Jana Frank, Ysaline Grand, Farid Mosbaoui, Emilie Hily, Anna Galea, Megane Peltret, Carole Estoppey, Daniel Ayoub, Roberto Giovannini, Martin Bertschinger

“…The pre-mRNA used in this study contains two open reading frames situated on separate exons. …”
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3D-Printed Tablets of Nifurtimox: In Vitro and In Vivo Anti-<i>Trypanosoma cruzi</i> Studies by Giselle R. Bedogni, Ana Luiza Lima, Idejan P. Gross, Tatiana Prata Menezes, Andre Talvani, Marcilio Cunha-Filho, Claudio J. Salomon

“…The printability of the obtained filaments was tested, and the polyvinyl alcohol filament was further used for printing tablets containing 120 and 60 mg of nifurtimox. <b>Results</b>: Three-dimensional tablets showed a remarkable improvement in the drug dissolution rate compared to commercial tablets and a dissolution efficiency 2.8 times higher. …”
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Long non-coding RNA SNHG17 may function as a competitive endogenous RNA in diffuse large B-cell lymphoma progression by sponging miR-34a-5p. by Shengjuan Lu, Lin Zeng, Guojun Mo, Danqing Lei, Yuanhong Li, Guodi Ou, Hailian Wu, Jie Sun, Chao Rong, Sha He, Dani Zhong, Qing Ke, Qingmei Zhang, Xiaohong Tan, Hong Cen, Xiaoxun Xie, Chengcheng Liao

“…We established a prognostic model containing SNHG17 expression, which could effectively predict the overall survival rate of DLBCL patients. …”
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Visual Hybridity: Margaret Murray Cookesley’s Orientalist Aestheticism by Julia Kuehn

“…By analysing a number of Cookesley’s Orientalist-Aestheticist paintings of harem women this essay thus suggests that Aestheticism was by no means a well-defined or self-contained artistic movement but was open enough to invite often bizarre hybrids like Cookesley’s works into its circle.…”
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