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1981
Targeted In Situ Gene Correction of Dysfunctional APOE Alleles to Produce Atheroprotective Plasma ApoE3 Protein
Published 2012-01-01“…In particular, we discuss the possibility and potential benefit of applying in combination two technical advances to repair aberrant APOE genes: (i) an engineered endonuclease to introduce a double-strand break (DSB) in exon 4, which contains the common, but dysfunctional, ε2 and ε4 alleles; (ii) an efficient and selectable template for homologous recombination (HR) repair, namely, an adeno-associated viral (AAV) vector, which harbours wild-type APOE sequence. …”
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1982
Oral administration of hydrolyzed collagen alleviates pain and enhances functionality in knee osteoarthritis: Results from a randomized, double-blind, placebo-controlled study
Published 2025-02-01“…This investigation aimed to evaluate the impact of a dietary supplement containing collagen peptides (MW 1–3 kDa) on knee OA symptoms and inflammatory biomarkers such as C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR). …”
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1983
Electromagnetic Compatibility of Compensating Devices and Converters of an Adjustable Electric Drive in Electrical Networks of Industrial Enterprises
Published 2022-02-01“…The present article identifies problems and proposes solutions in terms of reactive power compensation and improving the quality of electrical energy in electrical networks containing thyristor voltage converters and frequency converters used in adjustable electric drive installations of industrial enterprises.…”
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1984
Association of Choline Intake with Blood Pressure and Effects of Its Microbiota-Dependent Metabolite Trimethylamine-N-Oxide on Hypertension
Published 2022-01-01“…For the animal experimental study, spontaneously hypertensive rats (SHRs) were assigned to the water group or water containing 333 mg/L or 1 g/L TMAO group. After 22 weeks treatment of TMAO, blood pressure measurement, echocardiography, and histopathology of the heart and arteries were evaluated. …”
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1985
Permeation Enhancer in Microemulsions and Microemulsion-Based Gels: A Comparison of Diethylene Glycol Monoethyl Ether and Oleyl Alcohol
Published 2025-01-01“…However, there was a fourfold difference in drug permeation from these gels—a significantly higher permeation from the microemulsion-gel containing oleic acid and oleyl alcohol compared to the DGME formulation. …”
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1986
Search for supersymmetry using vector boson fusion signatures and missing transverse momentum in pp collisions at s $$ \sqrt{s} $$ = 13 TeV with the ATLAS detector
Published 2024-12-01“…The search uses 140 fb −1 of proton-proton collision data at s $$ \sqrt{s} $$ = 13 TeV collected by the ATLAS experiment at the Large Hadron Collider. Events containing at least two jets with a large gap in pseudorapidity, large missing transverse momentum, and no reconstructed leptons are selected. …”
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1987
Base Composition Characteristics of Mammalian miRNAs
Published 2013-01-01“…For this study, the author explored the base composition characteristics of miRNA genes from the six mammalian species that contain the largest number of known miRNAs. It was found that mammalian miRNAs are evolutionarily conserved and GU-rich. …”
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1988
Positive Solutions for a Class of Fourth-Order p-Laplacian Boundary Value Problem Involving Integral Conditions
Published 2015-01-01“…The interesting point of the results is that the nonlinear term contains all lower-order derivatives explicitly. Finally, we give some examples to demonstrate the main results.…”
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1989
Genetics and Molecular Biology of Epstein-Barr Virus-Encoded BART MicroRNA: A Paradigm for Viral Modulation of Host Immune Response Genes and Genome Stability
Published 2017-01-01“…EBV-encoded BZLF-1 (ZEBRA) protein could also regulate BART since ZEBRA contains a terminal region similar to ankyrin proteins such as IκBα that regulate host NF-κB. …”
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1990
Interactions of Cu-substrates with titanium-alloyed Sn-Zn solders
Published 2006-01-01“…The first one consisted in differential thermal analyses of Sn-Zn nearly eutectic alloys containing from 1.3 to 2.2 wt. % Ti. Diffusion couples consisted of Cu-wires and Sn-Zn-Ti liquid solders, produced at 250 and 275 OC have been prepared in the second series,. …”
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1991
Influencing factors of occupational stress and health effect among grassroots medical and health personnel in Xiong’an New Area, Hebei Province based on Bayesian network
Published 2024-12-01“…The final Bayesian network contained 14 nodes and 18 directed edges, and its prediction accuracy was 85.4%. .Job title, daily working hours, overcommitment and exercise directly associated with occupational stress, and other work and personal factors associated with occupational stress indirectly. …”
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1992
Building a sustainable institutional model for ornamental fish farming export villages in Indonesia
Published 2024-12-01“…To improve export competitiveness, it is also necessary to strengthen the cluster competitiveness through institutional development. Indonesia contains several ornamental fish-producing regions, and the government has designated several aquaculture farming villages, including four regions for ornamental fish farming. …”
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1993
The Chemical States of Color-Induced Cations in Tourmaline Characterized by X-Ray Photoelectron Spectroscopy
Published 2018-01-01“…Our results showed that the colorful tourmalines usually contained a small amount of transition metal elements, and a colorful tourmaline sample had several transition metal cations; however, the color of tourmaline resulted from the transition metal cations in the Y site of the crystal structure. …”
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1994
PRA Melting-ICE Project: Svalbard 2022 Expeditions Report [version 1; peer review: 2 approved]
Published 2024-12-01“…Increasing average temperatures over the last five decades have deepened the thawing of the upper-most layer of permafrost across the Arctic, which contains significant amounts of organic carbon. The progressive deepening of seasonal thawing releases carbon that is used by active microorganisms which also produce greenhouse gases, potentially onsetting a positive feedback on global warming. …”
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1995
An Inconsistency in the Spectrum of Bosonic Open 2-Brane
Published 2015-01-01“…Moreover, the spectrum of this open 2-brane only contains half integer mass squared values.…”
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1996
Adult Hip Flexion Contracture due to Neurological Disease: A New Treatment Protocol—Surgical Treatment of Neurological Hip Flexion Contracture
Published 2014-01-01“…Scientific literature contains many studies about children hip flexion related to neurological diseases, mainly caused by cerebral palsy; only few papers focus on this complication in adults. …”
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1997
A Comparative Study of Machine Learning Techniques for Predicting Mechanical Properties of Fused Deposition Modelling (FDM)-Based 3D-Printed Wood/PLA Biocomposite
Published 2025-08-01“…The dataset has been carefully prepared to facilitate machine learning for both training and testing, and it contains the experimental results and associated process parameters. …”
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1998
Composite Materials Based on Henequen Fiber as a Thermal Barrier in the Automotive Sector
Published 2019-01-01“…This research proposes the preparation of a composite material containing henequen natural fiber as a thermal barrier to be used as the roof of the car. …”
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1999
The technological reasons of the project: experiences from the School of Pescara
Published 2018-06-01“…This contribution, by looking at several experiences from the School of Architecture of Pescara, proposes some reflections regarding three emergent reasons that confirm how important it is that the training of future architects contain technological subjects. The relational reason, the reason of the processes and the performance reason can contribute in defining the multi/inter/transdisciplinary horizons of didactics, which are becoming more and more necessary when tackling the complexities of the habitat; both to bring it in line with the working market’s demand for new competences and to develop abilities to relate on more than one level and in multiple scales and temporal interventions.…”
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2000
Icings in the Selenga River basin
Published 2024-12-01“…The GIS dataset of icings is compiled using Landsat and Sentinel-2 satellite images, as well as materials from the field expedition studies. It contains 29,054 individual icings with a total area of 1154.2 km2 (0.25% of the entire basin area), including at least 56 giant icings with an area ≥ 1 km2. …”
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