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55781
THE DANUBE DELTA BIOSPHERE RESERVE. GEOGRAPHY, BIODIVERSITY, PROTECTION, MANAGEMENT
Published 2009-12-01“…Dans les limites sont compris: le delta proprement-dit, le complexe lacustre Razim-Sinoie, les eaux marines côtières, la plaine inondable du Danube entre Isaccea et Tulcea, le lit du Danube entre Cotul Pisicii (le Tournant du Chat) et Isaccea jusqu´à la frontière avec l’Ukraine.…”
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55782
Role of the Notch signaling pathway in porcine oocyte maturation
Published 2025-01-01“…Methods Reverse transcription-polymerase chain reaction (RT-PCR) and immunocytochemical assays were used to determine the existence of Notch signaling pathway-related transcripts and proteins in porcine cumulus–oocyte complexes (COCs). In vitro maturation (IVM) and parthenogenetic activation of oocytes were employed to examine the effects of Notch signaling inhibition on meiotic progression and embryogenesis of COCs using RO4929097 (RO), an inhibitor of γ secretase. …”
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55783
Larviciding for malaria control and elimination in Africa
Published 2025-01-01“…However, malaria programmes hoping to implement larviciding face significant barriers, including (1) poor global technical, policy, and funding support; (2) fragmented implementation and experience; (3) high complexity of delivery and impact evaluation; and (4) limited access to the full range of WHO prequalified larvicide products. …”
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55784
Le tourisme et l’imaginaire érotique à Paris durant la guerre : Français et Allemands pendant l’Occupation, 1940-1944
Published 2018-05-01“…En abordant les intersections complexes du tourisme, de la guerre et de l’érotisme, il cherche à encourager de futures recherches sur les relations qu’ils entretiennent.…”
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55785
Smart Pharmaceutical Monitoring System With Personalized Medication Schedules and Self-Management Programs for Patients With Diabetes: Development and Evaluation Study
Published 2025-02-01“…However, its effectiveness is often hindered by factors such as treatment complexity, polypharmacy, and poor patient adherence. …”
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55786
Les installations portuaires romaines d’Incarville (Eure)
Published 2020-12-01“…Three architectural complexes on stone foundations in particular testify to buildings that probably functioned mainly as warehouses. …”
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55787
Prevalence and health consequences of nonmedical use of tramadol in Africa: A systematic scoping review.
Published 2024-01-01“…The prevalence of misuse varies within sub-populations, indicating the complexity of the issue. Professional and academic groups have different rates of misuse across regions. …”
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55788
Comparative analysis of Sentinel-2 and PlanetScope imagery for chlorophyll-a prediction using machine learning models
Published 2025-03-01“…The findings contribute to advancing our understanding of the complexities associated with remote sensing technologies and their applications in water quality assessments, ultimately facilitating improved monitoring and management strategies for small inland water bodies.…”
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55789
Bioinformatics insights into mitochondrial and immune gene regulation in Alzheimer's disease
Published 2025-02-01“…After platform removal, there was a notable increase in the path complexity and time required to reach the target quadrant, suggesting a reduction in spatial memory capacity in AD mice. …”
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55790
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55791
Development and Evaluation of a Mental Health Chatbot Using ChatGPT 4.0: Mixed Methods User Experience Study With Korean Users
Published 2025-01-01“…However, areas for improvement were noted in professionalism (mean 7.0, SD 2.0), complexity of content (mean 7.4, SD 2.0), and personalization (mean 7.4, SD 2.4). …”
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55792
Analysis of the structure and function of the tomato <i>Solanum lycopersicum</i> L. MADS-box gene <i>SlMADS5</i>
Published 2021-09-01“…The E-proteins SEPALLATA are the central hub of the MADS-complexes, which determine the identity of the floral organs. …”
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55793
Optimizing composite ecological networks through Synergistic risk Management, ecological Conservation, and recreational Integration: A case study of Beijing’s shallow mountain regi...
Published 2025-01-01“…Key findings include: (1) The study identified 49 ecological source sites and 43 recreational source sites, along with 105 ecological corridors and 80 recreational corridors; (2) This research selected 54 ecological pinch points, 137 intersections between ecological and recreational corridors, and 283 alternative composite source points combining ecological and recreational resources; (3) This paper selected 140 composite source points and the construction of 128 composite corridors, 161 potential corridors, 371.82 km2 of risk prevention area, and 468.74 km2 of ecological protection area; (4) Network analysis revealed that the composite ecological network demonstrated superior closure, complexity, and connectivity compared to traditional methods; (5) This study proposed an optimization strategy for ecological spatial networks, based on the “patch-corridor-substrate” theory of landscape ecology, emphasizing 3 levels: ecological restoration, ecological protection, and the development of recreational systems. …”
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55794
Evolutionary and functional divergence of Sfx, a plasmid-encoded H-NS homolog, underlies the regulation of IncX plasmid conjugation
Published 2025-02-01“…Surprisingly, the loss of Sfx does not negatively affect the stability or dissemination of R6K in laboratory conditions, reflecting the complexity of selective pressures favoring conjugation repression. …”
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55795
Bacterial interactions underpin worsening lung function in cystic fibrosis-associated infections
Published 2025-01-01“…This work highlights the need to understand the interactive landscapes of the microbiomes to fully appreciate the complexity and treat chronic lung infections. Furthermore, this presents testable hypotheses for manipulative experiments in model systems to elucidate key mechanisms to driving disease progression.…”
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55796
Combating COVID-19 and its co-infection by Aspergillus tamarii SP73-EGY using in vitro and in silico Studies
Published 2025-01-01“…Molecular dynamics simulations were employed to examine the structural stability and flexibility of these complexes. This confirmed the high binding affinities of Kojic acid and 4(4-Methylbenzylidene)cyclohexane-1,3-dione, thereby proving their potential as novel anti-SARS-CoV-2.…”
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55798
Application of GUHA data mining method in cohort data to explore paths associated with premature death: a 29-year follow-up study
Published 2025-01-01“…This highlights the complexity of premature mortality and the need for comprehensive models considering multiple interacting factors.…”
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55799
Development of a Web-Based Intervention for Middle Managers to Enhance Resilience at the Individual, Team, and Organizational Levels in Health Care Systems: Multiphase Study
Published 2025-02-01“… BackgroundHealth care institutions face high systemic risk due to the inherent uncertainty and complexity of their operations. This often leads to stressful incidents impacting the well-being of health care professionals, which can compromise the effectiveness of health care systems. …”
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55800
Assessing institutional sanitation and its impact at a citywide level: an exploration of school sanitation in the Accra Metropolitan Area, Ghana
Published 2025-01-01“…However, current SFDGs assume that individuals use only home toilets, overlooking the complexity of toilet usage, including public and workplace facilities. …”
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