Immunoinformatics Approach to Design a Chimeric CD70-Peptide Vaccine against Renal Cell Carcinoma by Haideh Namdari, Farhad Rezaei, Fatemeh Heidarnejad, Mohammad Yaghoubzad-Maleki, Maryam Karamigolbaghi

“…To enhance immunogenicity, sequences of cell-penetrating peptide (CPP), penetratin (pAntp), along with the entire sequence of tumor necrosis factor-α (TNF-α), were attached to the N-terminal and C-terminal of the CD70 epitopes. Computational assessments were performed on these chimeric vaccines for antigenicity, allergenicity, peptide toxicity, population coverage, and physicochemical properties. …”
Get full text

Design of retrofit flue gas (CO2) scrubber for dependable clean energy at the Duvha Coal Power Plant by Hlamalani Innocent Baloyi, Leonard U. Okonye, Jianwei Ren

“…This study is based on chemical absorption, and explores the mechanistic design of the scrubber, which was accomplished through simple computations and Ansys simulations. The approach for developing a wet CO2 scrubber and LSTG system is based on chemical absorption and is integrated with a pilot plant. …”
Get full text

Location Information-Based Routing Protocol for Energy Harvesting Cognitive Radio Wireless Sensor Network by Mohamad-Rida Mortada, Abbass Nasser, Alaaeddine Ramadan, Koffi-Clement Yao, Ali Mansour

Get full text

Fast 3D Transmission Tower Detection Based on Virtual Views by Liwei Zhou, Jiaying Tan, Jing Fu, Guiwei Shao

“…However, traditional 3D target detection techniques, which involve searching the entire 3D space, are marred by low accuracy and high computational demands. Although deep learning-based 3D target detection methods have significantly improved detection precision, they rely on a large volume of 3D target samples for training and are sensitive to point cloud data density. …”
Get full text

Fueling the development of elderly care services in China with digital technology: A provincial panel data analysis by Jiaxin He, Dangchen Sui, Lingpeng Li, Xinyan Lv

“…Objective: This study aims to investigate the transformative potential of digital technology, which includes innovations such as e-commerce, cloud computing, and artificial intelligence, on elderly care cervices in China. …”
Get full text

Synthesis of Copper Oxide Nanoparticles Using Plant Leaf Extract of Catha edulis and Its Antibacterial Activity by Worku Wubet Andualem, Fedlu Kedir Sabir, Endale Tsegaye Mohammed, Hadgu Hailekiros Belay, Bedasa Abdisa Gonfa

Get full text

Identification of a Robust Five-Gene Risk Model in Prostate Cancer: A Robust Likelihood-Based Survival Analysis by Yutao Wang, Jiaxing Lin, Kexin Yan, Jianfeng Wang

“…FAM72D, ARHGAP33, TACR2, PLEK2, and FA2H were identified as independent prognosis factors in prostate cancer patients. We built the computing model as follows: CMU5 risk score = 1.158∗FAM72D + 1.737∗ARHGAP33 − 0.737∗TACR2 − 0.651∗PLEK2 − 0.793∗FA2H. …”
Get full text

Natural sampling and aliasing of marine geochemical signals by Andrew Curtis, Hugo Bloem, Rachel Wood, Fred Bowyer, Graham A. Shields, Ying Zhou, Mariana Yilales, Daniel Tetzlaff

“…Without absolute age constraints of sufficient resolution, the temporal correlation of spatially disjunct records is therefore problematic and uncertain, but these effects have rarely been analysed quantitatively using signal processing methods. Here we use a computational process model to illustrate and analyse how spatial and temporal geochemical records can be biased by the inherent, heterogenous processes of marine sedimentation and preservation. …”
Get full text

Development and validation of a tool for advising primiparous women during early labour: study protocol for the GebStart Study by Mechthild M Gross, Susanne Grylka-Baeschlin, Antonia N Mueller, Jessica Pehlke-Milde

“…Internal consistency of the tool will be assessed using Cronbach’s alpha and convergent validity computing correlations of items of the tool with the German versions of the Childbirth Self-Efficacy Inventory and the Cambridge-Worry Scale. …”
Get full text

A menu of standards for green infrastructure in England: effective and equitable or a race to the bottom? by Mike Grace, Alison Smith, Ian Mell, Jane Houghton, Peter Neal

Get full text

The Impact of the Internet of Things (IoT) on Healthcare Delivery: A Systematic Literature Review by Bismark Atta Frimpong, Cláudia Barbosa, Raed A Abd-Alhameed

Get full text

NIGWO-iCaps NN: A Method for the Fault Diagnosis of Fiber Optic Gyroscopes Based on Capsule Neural Networks by Nan Lu, Huaqiang Zhang, Chunmei Dong, Hongtao Li, Yu Chen

“…Traditional diagnostic models often encounter challenges in terms of reliability and accuracy, for example, difficulties in feature extraction, high computational cost, and long training time. To address these challenges, this paper proposes a new fault diagnostic model that performs a fault diagnosis of gyroscopes using the enhanced capsule neural network (iCaps NN) optimized by the improved gray wolf algorithm (NIGWO). …”
Get full text

Energy feature extraction and visualization of voltage sags using wavelet packet analysis for enhanced power quality monitoring by M. S. Priyadarshini, Mohit Bajaj, Ievgen Zaitsev

“…This study contributes to the development of advanced PQ monitoring systems by offering a more precise and computationally efficient method for voltage sag analysis, ultimately helping to protect electrical systems from potential damage and reducing operational costs. …”
Get full text

Estimating pros and cons of statistical downscaling based on EQM bias adjustment as a complementary method to dynamical downscaling by Alfredo Reder, Giusy Fedele, Ilenia Manco, Paola Mercogliano

“…Abstract The increasing availability of coarse-scale climate simulations and the need for ready-to-use high-resolution variables drive the climate community to the challenge of reducing computational resources and time for downscaling purposes. …”
Get full text

Analysis of water based Casson hybrid nanofluid (NiZnFe2O4+MnZnFe2O4) flow over an electromagnetic actuator with Cattaneo–Christov heat-mass flux: A modified Buongiorno model by S. Baskaran, R. Sowrirajan, S. Divya, S. Eswaramoorthi, K. Loganathan

Get full text

Explication of Pharmacological Proficiency of Phytoconstituents from Adansonia digitata Bark: An In Vitro and In Silico Approaches by Sangavi P., Gowtham Kumar S., Nachammai KT., Chandrabose Selvaraj, Langeswaran K.

“…The GC-MS and FT-IR studies revealed phytocompounds, which were then analyzed for their potential therapeutic properties. Computational studies were conducted on the phytocompounds against Pseudomonas aeruginosa and C2 kinase (antioxidant). …”
Get full text

Extending the Meshless Natural-Neighbour Radial-Point Interpolation Method to the Structural Optimization of an Automotive Part Using a Bi-Evolutionary Bone-Remodelling-Inspired Al... by Carlos Oliveira, Ana Pais, Jorge Belinha

“…Topological structural optimization is a powerful computational tool that enhances the structural efficiency of mechanical components. …”
Get full text

Definition of a Novel Cuproptosis-Relevant lncRNA Signature for Uncovering Distinct Survival, Genomic Alterations, and Treatment Implications in Lung Adenocarcinoma by Zhuning Wang, Junqiao Yao, Tengyu Dong, Xing Niu

“…Genomic alterations, immunological and stemness features, and therapeutic sensitivity were studied with a series of computational approaches. Results. Cuproptosis genes displayed aberrant expression and widespread genomic alterations across LUAD, potentially modulated by m6A/m5C/m1A RNA modification mechanisms. …”
Get full text

Modeling the Process of Obtaining Liquid Pyrolysis Products of Plant Biomass Taking into Account the Rate of their Cooling by S. V. Vasilevich, M. V. Malko, D. V. Degterov, A. N. Asadchy

“…The article presents the results of computational and experimental studies of thermochemical conversion of wood biomass to obtain liquid pyrolysis products taking into account their cooling rate. …”
Get full text

Impact of Post-Thaw Incubation Time of Frozen Embryos on Clinical Pregnancy Rate by G. Geovin Ranji, Kundavi Shankar, Yamini Asokan, Geetha Veerasigamani, Rashmi Gingade Vittal, Nithya M. Naaram, KR Hema Niveda

“…Statistical Analysis Used: Statistical analysis was performed using version 14 R software version 4.0.1 (2020-06-06) (R foundation for Statistical Computing, Vienna, Austria). A P < 0.05 is taken as significant. …”
Get full text