Applying the Block-Based Programming Language ALICE for Developing Programming Competencies in University Students by Mariuxi Vinueza-Morales, Jesennia Cardenas-Cobo, Jessica Cabezas-Quinto, Cristian Vidal-Silva

“…Today’s world needs professionals with computing competencies. Higher education programming classes usually use text-based programming languages to develop programming competencies, usually without success for all students. …”
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Exploring Zinc C295 as a Dual HIV-1 Integrase Inhibitor: From Strand Transfer to 3′-Processing Suppression by Sharif Karim Sayyed, Marzuqa Quraishi, D. S. Prabakaran, Balaji Chandrasekaran, Thiyagarajan Ramesh, Satish Kumar Rajasekharan, Chaitany Jayprakash Raorane, Tareeka Sonawane, Vinothkannan Ravichandran

“…<b>Results</b>: Zinc C295 demonstrated significant inhibition of HIV-1 integrase 3′P activity in in vitro assays (IC50 = 4.709 ± 0.97 µM). Computational analyses revealed key interactions of Zinc C295 within the enzyme’s allosteric site, providing insights into its dual inhibitory mechanism. …”
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Precision Analysis of Multi-Parameter Multi-Epoch Emitter Localization Radar in Three-Satellite Formation by Yiming Lian, Yuxuan Wu, Yaowen Chen, Xian Liu, Liming Jiang

“…Additionally, the results verify that an accumulated almanac element duration of 20 s ensures high positioning accuracy while maintaining a low computational cost. The combined multi-parameter multi-epoch method shows substantial advantages in improving both accuracy and robustness, providing valuable insights for future satellite-based emitter localization technologies.…”
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Pharmacophore-based approach for the identification of prospective UDP-2,3-diacylglucosamine hydrolase (LpxH) inhibitor from natural product database against Salmonella Typhi by Divyapriya Karthikeyan, Sanjit Kumar, NS Jayaprakash

“…This study illustrates how computational techniques, such as MD simulations and pharmacophore modeling, can speed up drug discovery, especially in the fight against antibiotic resistance.…”
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A Model of an Integrated Research and Education Program in Space Weather at a Community College by M. C. Damas, C. M. Ngwira, T. D. Cheung, P. Marchese, M. Kuznetsova, Y. Zheng, A. Chulaki, A. Mohamed

“…Space weather's impact on Earth's geospace environment, life, and society also provides a compelling real‐world hook to engage students in activities that have a number of impacts including (1) long‐term integration of space weather into the undergraduate curricula; (2) experience in analyzing large geospace data sets, which increases students' computational, critical thinking, and analytical skills, useful for any career; and (3) increase in students' interest in and motivation to study STEM, as well as preparing them for choosing a career path in space science and related fields. …”
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Technology first, sustainability later: a systematic review on the literature on the policy development of China’s smart city strategy by Ke Ge, Felix Creutzig, Marie Josefine Hintz

“…Unlike other countries, China pursued a smart city strategy since 2008 with substantial funding and intermediate goals, resulting in high data and computational-intensive digital infrastructures in some cities. …”
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Association between the exposure to brominated flame retardants and psoriasis risk among U.S. adults: A population-based study by Jingbo Zhang, Xiangyun Shi, Genlong Bai, Jin Chen, Yidian Fu, Aijun Chen

“…Multivariable logistic regression, restricted cubic splines (RCS), weighted quantile sum (WQS) regression, quantile-based g computation (Qgcomp) regression, and Bayesian kernel machine regression (BKMR) models were performed to estimate the associations. …”
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Numerical investigation on heat transfer and flow mechanism in microchannel heat sink having V shape ribs by Naushad Ali, Injamamul Haque, Tabish Alam, Tauseef Uddin Siddiqui, Mushtaq Ahmad Ansari, Jagmohan Yadav, Shivam Srivastava, Erdem Cuce, Intesaaf Ashraf, Dan Dobrotă

“…This research comprehensively examines the influence of the V-shaped rib angle of attack on the thermal and hydraulic efficacy of microchannel heat sinks (MCHS), employing Computational Fluid Dynamics (CFD) simulations over Reynolds numbers ranging from 100 to 900. …”
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Rapid and non-destructive classification of rice seeds with different flavors: an approach based on HPFasterNet by Helong Yu, Helong Yu, Zhenyang Chen, Shaozhong Song, Shaozhong Song, Shaozhong Song, Chunyan Qi, Junling Liu, Chenglin Yang

“…The results show that HPFasterNet has the highest classification accuracy of 92%, which is 5.22% better than the original model FasterNet_T0, and the number of parameters and computation is significantly reduced compared to the original model, which is more suitable for resource-limited environments. …”
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Influence of bio-filter configurations on hydraulic aspects while enhancing the sustainable self-purification of agricultural drainage water by Raid Alrowais, Raid Alrowais, Ashraf Jatwary, Marcela Bindzarova Gergelova, Mohammad Akrami, Bandar Alwushayh, Elsayed Elkamhawy, Elsayed Elkamhawy

“…This study assessed the hydraulic impacts of installing these bioreactors in polluted waterways using three-dimensional numerical models based on computational fluid dynamics. Results indicated that relative heading-up will increase with the Froude number, demonstrating a direct relationship between flow velocity and heading-up. …”
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Well-Production Forecasting Using Machine Learning with Feature Selection and Automatic Hyperparameter Optimization by Ruibin Zhu, Ning Li, Yongqiang Duan, Gaofeng Li, Guohua Liu, Fengjiao Qu, Changjun Long, Xin Wang, Qinzhuo Liao, Gensheng Li

“…Traditional methods, such as numerical simulations, require substantial computational effort, while empirical models tend to exhibit poor accuracy. …”
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An approach for accurate identification and monitoring of species in mangrove forests based on multi-source spectral data and deep learning by Monterrubio-Martínez Erandi, Trujillo-Acatitla Rubicel, Tuxpan-Vargas José, Moreno-Casasola Patricia

“…Furthermore, the multispectral data obtained from the Sentinel-2 satellite was employed for the training of multilayer perceptron models (MLP) that are capable of accurately mapping mixed and monospecific mangrove forests. The computational experiments for MLP models involve different number of neurons and hidden layers. …”
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The Study of Viral RNA Diversity in Bird Samples Using De Novo Designed Multiplex Genus-Specific Primer Panels by Andrey A. Ayginin, Ekaterina V. Pimkina, Alina D. Matsvay, Anna S. Speranskaya, Marina V. Safonova, Ekaterina A. Blinova, Ilya V. Artyushin, Vladimir G. Dedkov, German A. Shipulin, Kamil Khafizov

“…In this study, we have developed a computational pipeline for designing the oligonucleotides capable of covering a significant number of known viruses within various taxonomic orders, as well as their novel variants. …”
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Optimization of Reasonable Finished State for Cable-Stayed Bridge with Steel Box Girder Based on Multiplier Path Following Method by Jiapeng Shi, Yu Tao, Qingyun Xu, Jie Dai, Jin Di, Fengjiang Qin

“…The multiplier path following optimization algorithm is computationally efficient, exhibiting good convergence and insensitivity to the problem size. …”
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Divergence of alpine plant populations of three Gentianaceae species in the Qinling sky Island by Peng-Cheng Fu, Bing-Jie Mo, He-Xin Wan, Shu-Wen Yang, Rui Xing, Shan-Shan Sun

“…Divergence time estimation based on plastomes and approximate Bayesian computation based on genomic SNPs showed that Qinling populations of the three Gentianaceae species originated at different periods under various patterns including primary source and hybridization. …”
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Identifying time patterns in Huntington’s disease trajectories using dynamic time warping-based clustering on multi-modal data by Alexia Giannoula, Audrey E. De Paepe, Ferran Sanz, Laura I. Furlong, Estela Camara

“…However, extracting meaningful information from Real-World Data, such as Electronic Health Records, still remains challenging due to methodological and computational issues. A Dynamic Time Warping-based unsupervised-clustering methodology is presented in this paper for the clustering of patient trajectories of multi-modal health data on the basis of shared temporal characteristics. …”
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Inerting Strategy for a Demonstration-Scale Hot Cell Facility Based on Experiences from Pilot-Scale Argon Cell Facility Operation and CFD Analysis by Seungnam Yu, Jaehoon Lim, Ilje Cho, Jonghui Han

“…The study applies the inerting strategy to a demonstration-scale hot cell facility beyond that of the currently existing pilot-scale hot cell facility and performs computational fluid dynamics (CFD) simulation with various flow rates to determine an appropriate approach for inerting the target facility. …”
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Semiclassical Estimates of Pressure-induced Line Widths for Infrared Absorption in Hot (Exo)planetary Atmospheres by Jeanna Buldyreva, Kathleen Stehlin, Sergei N. Yurchenko, Elizabeth R. Guest, Jonathan Tennyson

“…Advanced theoretical approaches (classical, semiclassical, and quantum mechanical), without mentioning their high computational cost, are also impracticable due to the lack of potential energy surfaces. …”
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The clinical application of artificial intelligence in cancer precision treatment by Jinyu Wang, Ziyi Zeng, Zehua Li, Guangyue Liu, Shunhong Zhang, Chenchen Luo, Saidi Hu, Siran Wan, Linyong Zhao

“…Abstract Background Artificial intelligence has made significant contributions to oncology through the availability of high-dimensional datasets and advances in computing and deep learning. Cancer precision medicine aims to optimize therapeutic outcomes and reduce side effects for individual cancer patients. …”
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How to Achieve Efficiency and Accuracy in Discrete Element Simulation of Asphalt Mixture: A DRF-Based Equivalent Model for Asphalt Sand Mortar by Yu Liu, Peifeng Su, Miaomiao Li, Hui Yao, Junfu Liu, Mei Xu, Xiaodong Zhou, Zhanping You

“…However, modelling of asphalt sand mortar in this method remains to be a problem due to computing capacity. Larger-sized balls (generally 2.0–2.36 mm) were usually used to model the smaller particles and asphalt binder, but this replacement may result in the mixture’s unrealistic volumetric features. …”
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